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The map label for this gene is ackA [H]

Identifier: 116622361

GI number: 116622361

Start: 4119480

End: 4120571

Strand: Reverse

Name: ackA [H]

Synonym: Acid_3255

Alternate gene names: 116622361

Gene position: 4120571-4119480 (Counterclockwise)

Preceding gene: 116622362

Following gene: 116622358

Centisome position: 41.35

GC content: 64.38

Gene sequence:

>1092_bases
ATGAACCTACTTATACCGAACCTGGGATCGACTTCCCTCAAGTATCAGATTCTGGAGATGCCGTCGGAAACGGCGATTGC
CAAGGGCCGGCTGGAGCGCGTCACAGATTATCGCGAGGCAATCGCGCAGATCTCTACCGCCGGCGCCGCGATCGACGGGA
TTGCCCTGAAGGCCGTACACGCGGGGCCGGAGTATCGTGGAACCTTCGTGGTGGACGCGGATCTGATGGCGGCGCTGCGG
CAGTTTCTGCCGGCGGCGCCGGCCCACAACGCGATTTACCTGACGGCGATCGAGGCCTTTCAGGAGGCGATGCCGGGAGT
GCCGATCGTGTGCGCGTTCGAACCGGAGTTCCACGCCACGATGCCGGAGTATGCGCGAATGTACGGCGTCCCCGGACAAT
GGCGGGAAGAAGGAGTGGTGAAGTACGGCTTCCACGGCGCGTCGCATCAGTTTATCGGCGAGCGCGTAACGGAGATGCTG
GGGCGCCCGGTGAAGCTGGTGAGCTGCCATCTGGGCGGAAGTTCGTCGATGTGCGCGATCGACCGCGGACGGTCAGTGGA
CACCACGATGGGATTCTCGCCGCAATCTGGCTTGGAGAACGCGACGCGGCACGGGGACCTGGATGTGTTCGCGGTGCTCT
ACATGATGGAGCGCCACGGATGGTGCGCGGACGAGGTCCGGCAGCAACTGGCGAAGGGCGGCGGATTAGCCGGACTATCC
GGCGTGCCAGGCGGCGACGTCCGCGACCTCGAGGCGGCCGGGACGGAGCGTGCCGCGCTGGCGCTCGAGGTGTTCGTGTA
CCAGGTGAAAAAGACGATCGGCGCGTACGCGGCTGCGATGGGTGGAATTGACGCAGTGGCCTTCACTGGCGGGATCGGCG
AGAACTCGGCACGGCTGCGGGAGAAATGCTGCGCGGGGCTGGAGTTCCTGGGGATCGAACTGGACGCGGAAAAGAATGCC
GGAACAGGGGACCGCGTGGTCTCACGCGGGAAGGTAGCGGTACTGGCGGTCGCCACGAATGAAGAGCTGGTAGTGGCAAG
GCGGGCGTACCGGTGTTTGGGAAAGGCTAAAGCAGAAATGGGCCGCGGATGA

Upstream 100 bases:

>100_bases
GGGCGCGAGAAGGCTGCGCTGACGAAGTTCGACGGCGACGAACCGGCGGCGAGTTTGAAGCAATTCGGGCTGGTGGAGTG
ATGCCTGCCCTGCGAGAACC

Downstream 100 bases:

>100_bases
ACACGGATCAACGCGGATAAAACAATGCTTCTTCTTATCTGCGTTTATCTGCGTTCATCTGCGGCCCGAAATTCTTTAGC
CGTCGCGGCGCTTTAAGGTC

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNLLIPNLGSTSLKYQILEMPSETAIAKGRLERVTDYREAIAQISTAGAAIDGIALKAVHAGPEYRGTFVVDADLMAALR
QFLPAAPAHNAIYLTAIEAFQEAMPGVPIVCAFEPEFHATMPEYARMYGVPGQWREEGVVKYGFHGASHQFIGERVTEML
GRPVKLVSCHLGGSSSMCAIDRGRSVDTTMGFSPQSGLENATRHGDLDVFAVLYMMERHGWCADEVRQQLAKGGGLAGLS
GVPGGDVRDLEAAGTERAALALEVFVYQVKKTIGAYAAAMGGIDAVAFTGGIGENSARLREKCCAGLEFLGIELDAEKNA
GTGDRVVSRGKVAVLAVATNEELVVARRAYRCLGKAKAEMGRG

Sequences:

>Translated_363_residues
MNLLIPNLGSTSLKYQILEMPSETAIAKGRLERVTDYREAIAQISTAGAAIDGIALKAVHAGPEYRGTFVVDADLMAALR
QFLPAAPAHNAIYLTAIEAFQEAMPGVPIVCAFEPEFHATMPEYARMYGVPGQWREEGVVKYGFHGASHQFIGERVTEML
GRPVKLVSCHLGGSSSMCAIDRGRSVDTTMGFSPQSGLENATRHGDLDVFAVLYMMERHGWCADEVRQQLAKGGGLAGLS
GVPGGDVRDLEAAGTERAALALEVFVYQVKKTIGAYAAAMGGIDAVAFTGGIGENSARLREKCCAGLEFLGIELDAEKNA
GTGDRVVSRGKVAVLAVATNEELVVARRAYRCLGKAKAEMGRG
>Mature_363_residues
MNLLIPNLGSTSLKYQILEMPSETAIAKGRLERVTDYREAIAQISTAGAAIDGIALKAVHAGPEYRGTFVVDADLMAALR
QFLPAAPAHNAIYLTAIEAFQEAMPGVPIVCAFEPEFHATMPEYARMYGVPGQWREEGVVKYGFHGASHQFIGERVTEML
GRPVKLVSCHLGGSSSMCAIDRGRSVDTTMGFSPQSGLENATRHGDLDVFAVLYMMERHGWCADEVRQQLAKGGGLAGLS
GVPGGDVRDLEAAGTERAALALEVFVYQVKKTIGAYAAAMGGIDAVAFTGGIGENSARLREKCCAGLEFLGIELDAEKNA
GTGDRVVSRGKVAVLAVATNEELVVARRAYRCLGKAKAEMGRG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=393, Percent_Identity=34.0966921119593, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1788633, Length=324, Percent_Identity=36.4197530864198, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 38614; Mature: 38614

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLIPNLGSTSLKYQILEMPSETAIAKGRLERVTDYREAIAQISTAGAAIDGIALKAVH
CCEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEEEEEE
AGPEYRGTFVVDADLMAALRQFLPAAPAHNAIYLTAIEAFQEAMPGVPIVCAFEPEFHAT
CCCCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCCCEEEEEECCCCCCC
MPEYARMYGVPGQWREEGVVKYGFHGASHQFIGERVTEMLGRPVKLVSCHLGGSSSMCAI
CHHHHHHCCCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
DRGRSVDTTMGFSPQSGLENATRHGDLDVFAVLYMMERHGWCADEVRQQLAKGGGLAGLS
CCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
GVPGGDVRDLEAAGTERAALALEVFVYQVKKTIGAYAAAMGGIDAVAFTGGIGENSARLR
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
EKCCAGLEFLGIELDAEKNAGTGDRVVSRGKVAVLAVATNEELVVARRAYRCLGKAKAEM
HHHHCCCEEEEEEEECCCCCCCHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHC
GRG
CCC
>Mature Secondary Structure
MNLLIPNLGSTSLKYQILEMPSETAIAKGRLERVTDYREAIAQISTAGAAIDGIALKAVH
CCEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEEEEEE
AGPEYRGTFVVDADLMAALRQFLPAAPAHNAIYLTAIEAFQEAMPGVPIVCAFEPEFHAT
CCCCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCCCEEEEEECCCCCCC
MPEYARMYGVPGQWREEGVVKYGFHGASHQFIGERVTEMLGRPVKLVSCHLGGSSSMCAI
CHHHHHHCCCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
DRGRSVDTTMGFSPQSGLENATRHGDLDVFAVLYMMERHGWCADEVRQQLAKGGGLAGLS
CCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
GVPGGDVRDLEAAGTERAALALEVFVYQVKKTIGAYAAAMGGIDAVAFTGGIGENSARLR
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
EKCCAGLEFLGIELDAEKNAGTGDRVVSRGKVAVLAVATNEELVVARRAYRCLGKAKAEM
HHHHCCCEEEEEEEECCCCCCCHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHC
GRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA