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The map label for this gene is atoS [C]

Identifier: 116621909

GI number: 116621909

Start: 3540862

End: 3542583

Strand: Direct

Name: atoS [C]

Synonym: Acid_2794

Alternate gene names: 116621909

Gene position: 3540862-3542583 (Clockwise)

Preceding gene: 116621908

Following gene: 116621910

Centisome position: 35.53

GC content: 60.34

Gene sequence:

>1722_bases
ATGGCCCGGAGGCCGCATGACAAGTCGCGTTATCGTGAGCGGGACCGCCGCGAGAAGGCGAACGAAAAAAATCACCTGGC
CGGCGTGCGCACGAACTTCCGAGGTGGACGGATGAGCCGGGAAGGGCGTGGGGCAGGAAATGAGTCCTCAGGAAGTGGGG
CCGCTGCCCGCGAGACTCGGGAGAGGCCGACCGTCCCGGGATTTCAGGCTCCCGCCGAAATGGCCGGCGCACTGCTGGAG
TCTGCCTCCCAGGCGATTGTCAGCGCAGATCAGGCCGGCACAATTGTTCTCGTGAACCGCCAGGCCGAGGAGATGTTCGG
CTACCACCGTGAAGAGCTTCTCGGCTCACCCATTGAGATCCTGCTGCCGGAAGTGAAGCGCGCAGCCCACGTTCAGATGC
GGGCCGAATATTTGCGGCGGCAAACCATCCGCCCGATGGGGAGCGGACTCGATTTGTCGGCCCGCCGAAAAGATGGCAGC
CAGTTTCCAGTCGAAGTGGGGCTCAGTCACATTAAAACCGCCAATGGCGTTTTTGCGATCGCGTTTATCAGTGACATCAG
CCAGCGGAAGCGGCTGGAACAACAGTTGCAGCTGGCTCAGAAGATGGAGGCTGTGGGTCGGCTGGCCGGCGGCATCGCCC
ACGATTTCAATAACATGCTTACGGTGATCGCCGGTTACGGATCCATGATCATGGAGAAATTGCAAGCGCAAGATCCGTTG
CGGGACCATGTGGAGGAGATTGTTGCAGCGACGACTCGAGCCGCGGCTCTGACGAGCCAATTGCTGGCGTTTAGCCGGCA
AGGACGGACGCGGCCCCAACCGATCAACCTGAATGAGTTGATCGCCAATATCGAGAAAATGCTGCGGCGGCTGATCCGTG
AGGACATTGCGCTGGAATTGATTCTTCAAGACGGGCTGCTGAGCGTGAAGGCTGATCCCGACCGGGTGGAACAGGCGATC
GTCAACCTGGTTGTGAACGCTCGGGACGCGATGCCGGGAGCGGGCCGGATCACAGTCGAAACCGCAAACGTGTACCTCGA
CGAGTCCTATGCCCGCTCGCACGTTGGGGTTCAGCCAGGGGAATTTGCGATGATCGCCGTGAGCGATACCGGGACGGGCA
TGGATCCGGAGGTGATGCGACGGATCTTCGAACCGTTTTTCACCACTAAGGCGCAGGGGAAAGGTGTCGGTTTGGGGCTT
GCCACGGTTTACGGAATGGTAAAGCAGGCCGGCGGTGGCATCTGGGTTTACAGCGAGCCTGGCAAAGGCACTACATTCAA
AGCATACTTTCCGATTGCGGGCGATACGGTCGCGACGTCATCGGCTGCGACTGTGCAGACAGCAGTACCCGGCGACGAGA
CGATTCTAGTGGTTGAGGACGACGCCTCGGTTCGAAGCGTAACCGTAAAGATGTTGGAGCAACTCGGATATGTGGCGCTG
GCGGCCGGCAATGGCGCAGAGGCCCTGGCGAAGAGCAAAGCCCACAGCGGGACGATCGCGCTGGTGGTCACCGATGTGGT
GATGCCGAATATGGGCGGATGCCAACTGGCGGCCGAGCTGGCCGGCACGCGGCCGGATATCAAAGTGCTCTACCTTTCGG
GATACACGGAGAGTGTTGCGATCCAAAGAGGCATGATCGACGGGACGGTCCCGTTCCTGGCCAAGCCGTTCAACCGCCAG
GTACTCGCAAAAACCATACGCTGCGTGCTGGATGGCAGGTAA

Upstream 100 bases:

>100_bases
TCTACGACGGGAATTGTCGTAAAGAAAAAACAAATTTGTATCTGTATCGCATGAAGCCCCAGGCTACGTGAGTTTCGCCG
GCCTTTCAGTGGTGGCTCTC

Downstream 100 bases:

>100_bases
TTTCCGCCTTAACCTGGACCGATGATTGGTATATCATCGTTGAACCTGGCCGGTGTCACGACGACGGCGAGCACATTCGA
ACGAAATCATCGCGGAGCAG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MARRPHDKSRYRERDRREKANEKNHLAGVRTNFRGGRMSREGRGAGNESSGSGAAARETRERPTVPGFQAPAEMAGALLE
SASQAIVSADQAGTIVLVNRQAEEMFGYHREELLGSPIEILLPEVKRAAHVQMRAEYLRRQTIRPMGSGLDLSARRKDGS
QFPVEVGLSHIKTANGVFAIAFISDISQRKRLEQQLQLAQKMEAVGRLAGGIAHDFNNMLTVIAGYGSMIMEKLQAQDPL
RDHVEEIVAATTRAAALTSQLLAFSRQGRTRPQPINLNELIANIEKMLRRLIREDIALELILQDGLLSVKADPDRVEQAI
VNLVVNARDAMPGAGRITVETANVYLDESYARSHVGVQPGEFAMIAVSDTGTGMDPEVMRRIFEPFFTTKAQGKGVGLGL
ATVYGMVKQAGGGIWVYSEPGKGTTFKAYFPIAGDTVATSSAATVQTAVPGDETILVVEDDASVRSVTVKMLEQLGYVAL
AAGNGAEALAKSKAHSGTIALVVTDVVMPNMGGCQLAAELAGTRPDIKVLYLSGYTESVAIQRGMIDGTVPFLAKPFNRQ
VLAKTIRCVLDGR

Sequences:

>Translated_573_residues
MARRPHDKSRYRERDRREKANEKNHLAGVRTNFRGGRMSREGRGAGNESSGSGAAARETRERPTVPGFQAPAEMAGALLE
SASQAIVSADQAGTIVLVNRQAEEMFGYHREELLGSPIEILLPEVKRAAHVQMRAEYLRRQTIRPMGSGLDLSARRKDGS
QFPVEVGLSHIKTANGVFAIAFISDISQRKRLEQQLQLAQKMEAVGRLAGGIAHDFNNMLTVIAGYGSMIMEKLQAQDPL
RDHVEEIVAATTRAAALTSQLLAFSRQGRTRPQPINLNELIANIEKMLRRLIREDIALELILQDGLLSVKADPDRVEQAI
VNLVVNARDAMPGAGRITVETANVYLDESYARSHVGVQPGEFAMIAVSDTGTGMDPEVMRRIFEPFFTTKAQGKGVGLGL
ATVYGMVKQAGGGIWVYSEPGKGTTFKAYFPIAGDTVATSSAATVQTAVPGDETILVVEDDASVRSVTVKMLEQLGYVAL
AAGNGAEALAKSKAHSGTIALVVTDVVMPNMGGCQLAAELAGTRPDIKVLYLSGYTESVAIQRGMIDGTVPFLAKPFNRQ
VLAKTIRCVLDGR
>Mature_572_residues
ARRPHDKSRYRERDRREKANEKNHLAGVRTNFRGGRMSREGRGAGNESSGSGAAARETRERPTVPGFQAPAEMAGALLES
ASQAIVSADQAGTIVLVNRQAEEMFGYHREELLGSPIEILLPEVKRAAHVQMRAEYLRRQTIRPMGSGLDLSARRKDGSQ
FPVEVGLSHIKTANGVFAIAFISDISQRKRLEQQLQLAQKMEAVGRLAGGIAHDFNNMLTVIAGYGSMIMEKLQAQDPLR
DHVEEIVAATTRAAALTSQLLAFSRQGRTRPQPINLNELIANIEKMLRRLIREDIALELILQDGLLSVKADPDRVEQAIV
NLVVNARDAMPGAGRITVETANVYLDESYARSHVGVQPGEFAMIAVSDTGTGMDPEVMRRIFEPFFTTKAQGKGVGLGLA
TVYGMVKQAGGGIWVYSEPGKGTTFKAYFPIAGDTVATSSAATVQTAVPGDETILVVEDDASVRSVTVKMLEQLGYVALA
AGNGAEALAKSKAHSGTIALVVTDVVMPNMGGCQLAAELAGTRPDIKVLYLSGYTESVAIQRGMIDGTVPFLAKPFNRQV
LAKTIRCVLDGR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=28.2548476454294, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=32.2448979591837, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI87081816, Length=273, Percent_Identity=28.9377289377289, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=30, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=290, Percent_Identity=26.551724137931, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=413, Percent_Identity=26.1501210653753, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=375, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786600, Length=370, Percent_Identity=27.8378378378378, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61879; Mature: 61748

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRPHDKSRYRERDRREKANEKNHLAGVRTNFRGGRMSREGRGAGNESSGSGAAARETR
CCCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHC
ERPTVPGFQAPAEMAGALLESASQAIVSADQAGTIVLVNRQAEEMFGYHREELLGSPIEI
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHCCCHHHHCCCCHHH
LLPEVKRAAHVQMRAEYLRRQTIRPMGSGLDLSARRKDGSQFPVEVGLSHIKTANGVFAI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEE
AFISDISQRKRLEQQLQLAQKMEAVGRLAGGIAHDFNNMLTVIAGYGSMIMEKLQAQDPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RDHVEEIVAATTRAAALTSQLLAFSRQGRTRPQPINLNELIANIEKMLRRLIREDIALEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILQDGLLSVKADPDRVEQAIVNLVVNARDAMPGAGRITVETANVYLDESYARSHVGVQPG
HHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCHHHHHCCCCCCC
EFAMIAVSDTGTGMDPEVMRRIFEPFFTTKAQGKGVGLGLATVYGMVKQAGGGIWVYSEP
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEECC
GKGTTFKAYFPIAGDTVATSSAATVQTAVPGDETILVVEDDASVRSVTVKMLEQLGYVAL
CCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCEEEE
AAGNGAEALAKSKAHSGTIALVVTDVVMPNMGGCQLAAELAGTRPDIKVLYLSGYTESVA
ECCCCHHHHHHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCHHHH
IQRGMIDGTVPFLAKPFNRQVLAKTIRCVLDGR
HHCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARRPHDKSRYRERDRREKANEKNHLAGVRTNFRGGRMSREGRGAGNESSGSGAAARETR
CCCCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHC
ERPTVPGFQAPAEMAGALLESASQAIVSADQAGTIVLVNRQAEEMFGYHREELLGSPIEI
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHCCCHHHHCCCCHHH
LLPEVKRAAHVQMRAEYLRRQTIRPMGSGLDLSARRKDGSQFPVEVGLSHIKTANGVFAI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEE
AFISDISQRKRLEQQLQLAQKMEAVGRLAGGIAHDFNNMLTVIAGYGSMIMEKLQAQDPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RDHVEEIVAATTRAAALTSQLLAFSRQGRTRPQPINLNELIANIEKMLRRLIREDIALEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILQDGLLSVKADPDRVEQAIVNLVVNARDAMPGAGRITVETANVYLDESYARSHVGVQPG
HHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCHHHHHCCCCCCC
EFAMIAVSDTGTGMDPEVMRRIFEPFFTTKAQGKGVGLGLATVYGMVKQAGGGIWVYSEP
CEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEECC
GKGTTFKAYFPIAGDTVATSSAATVQTAVPGDETILVVEDDASVRSVTVKMLEQLGYVAL
CCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCEEEE
AAGNGAEALAKSKAHSGTIALVVTDVVMPNMGGCQLAAELAGTRPDIKVLYLSGYTESVA
ECCCCHHHHHHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCHHHH
IQRGMIDGTVPFLAKPFNRQVLAKTIRCVLDGR
HHCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA