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The map label for this gene is nreC [H]

Identifier: 116621908

GI number: 116621908

Start: 3539998

End: 3540642

Strand: Direct

Name: nreC [H]

Synonym: Acid_2793

Alternate gene names: 116621908

Gene position: 3539998-3540642 (Clockwise)

Preceding gene: 116621907

Following gene: 116621909

Centisome position: 35.52

GC content: 54.57

Gene sequence:

>645_bases
TTGAGAAAATTGCGCATTCTGCTGGGAGATGACCATGCCATGATCCTGAGCGGGATCAAGGGACTGCTTGAAGGTCATTA
CGAGGTGATCGGGTCCGAGAAGAACGGCCGGGCTCTGATTGAGACAGCGGTGCGCCTGAAACCCGATCTGGTGGTTTTGG
ACGTGAGCATGCCGATTTTGAATGGGATCGATGCCGCGCGCGAGATCAAGAAGGCGCTTCCGGCGGCGAAGCTAATATTT
CTTACGATGCATACGAATGCAATTTATTTGCGAAAGGCATTGCATGCCGGCGCTTCGGGTTATGTGCTTAAGTCTGGCGC
GGCCGAGGAGCTACTCACCGCAATCGAAGAGGTTTGTAAAGGATACATCTATGTTGGCCCTGATTTTGGGCAGGATGTGA
TTGAGAGTATCCGGAGCACGGGAGACAGCCAGGGCGGGCTGCCCGCGTTGACAGACCGGCAGAGGCACATTCTTCAACTT
CTGGCCGAAGGCAAACAGAACAAAGAAATCGGAGAGATAGCGCATATTTCGGTGCGAACCGTGGAGTTTCACCGAAGCCG
CCTTATGTCCAGGCTAGGCGCGCACAGTGTTGCGGAACTCACCAGGTTCGCGATCCAGGAAGGTCTGATAGACGGCGAGA
CGTGA

Upstream 100 bases:

>100_bases
AGGAGCGGGTCAAAATGGCGAACGGAACTCTTTTGATCACCTCCCAGCCGGGACAAGGTACGGAGATTGTCGCCAGCGTT
CCACTAACGGGAGGAGCGGC

Downstream 100 bases:

>100_bases
GGTGAAATACCACAACGCTTATACGCGGGTAAGTTATCGCGCCGCCATTCGGCAAAACTAGTAATCTCACTAGGTGTCGT
TCAGCACATCGTCGATTAGA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRKLRILLGDDHAMILSGIKGLLEGHYEVIGSEKNGRALIETAVRLKPDLVVLDVSMPILNGIDAAREIKKALPAAKLIF
LTMHTNAIYLRKALHAGASGYVLKSGAAEELLTAIEEVCKGYIYVGPDFGQDVIESIRSTGDSQGGLPALTDRQRHILQL
LAEGKQNKEIGEIAHISVRTVEFHRSRLMSRLGAHSVAELTRFAIQEGLIDGET

Sequences:

>Translated_214_residues
MRKLRILLGDDHAMILSGIKGLLEGHYEVIGSEKNGRALIETAVRLKPDLVVLDVSMPILNGIDAAREIKKALPAAKLIF
LTMHTNAIYLRKALHAGASGYVLKSGAAEELLTAIEEVCKGYIYVGPDFGQDVIESIRSTGDSQGGLPALTDRQRHILQL
LAEGKQNKEIGEIAHISVRTVEFHRSRLMSRLGAHSVAELTRFAIQEGLIDGET
>Mature_214_residues
MRKLRILLGDDHAMILSGIKGLLEGHYEVIGSEKNGRALIETAVRLKPDLVVLDVSMPILNGIDAAREIKKALPAAKLIF
LTMHTNAIYLRKALHAGASGYVLKSGAAEELLTAIEEVCKGYIYVGPDFGQDVIESIRSTGDSQGGLPALTDRQRHILQL
LAEGKQNKEIGEIAHISVRTVEFHRSRLMSRLGAHSVAELTRFAIQEGLIDGET

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=32.3943661971831, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=28.5024154589372, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788712, Length=196, Percent_Identity=29.0816326530612, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=30.8056872037915, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=29.3532338308458, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=31.8681318681319, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23327; Mature: 23327

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLRILLGDDHAMILSGIKGLLEGHYEVIGSEKNGRALIETAVRLKPDLVVLDVSMPIL
CCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCHHH
NGIDAAREIKKALPAAKLIFLTMHTNAIYLRKALHAGASGYVLKSGAAEELLTAIEEVCK
HHHHHHHHHHHHCCHHHEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHC
GYIYVGPDFGQDVIESIRSTGDSQGGLPALTDRQRHILQLLAEGKQNKEIGEIAHISVRT
CEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHEEHHH
VEFHRSRLMSRLGAHSVAELTRFAIQEGLIDGET
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKLRILLGDDHAMILSGIKGLLEGHYEVIGSEKNGRALIETAVRLKPDLVVLDVSMPIL
CCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCHHH
NGIDAAREIKKALPAAKLIFLTMHTNAIYLRKALHAGASGYVLKSGAAEELLTAIEEVCK
HHHHHHHHHHHHCCHHHEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHC
GYIYVGPDFGQDVIESIRSTGDSQGGLPALTDRQRHILQLLAEGKQNKEIGEIAHISVRT
CEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHEEHHH
VEFHRSRLMSRLGAHSVAELTRFAIQEGLIDGET
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA