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The map label for this gene is aroC

Identifier: 116621862

GI number: 116621862

Start: 3482778

End: 3483947

Strand: Direct

Name: aroC

Synonym: Acid_2745

Alternate gene names: 116621862

Gene position: 3482778-3483947 (Clockwise)

Preceding gene: 116621860

Following gene: 116621863

Centisome position: 34.95

GC content: 65.21

Gene sequence:

>1170_bases
ATGCTGCGATTTGAGACGGCCGGAGAGTCCCACGGCGAGTGCCTGGTGGCCACCATGAACGGGCTCCCTGCCGGAATACC
CATATCTTTGGAAACCGTCAACCGCGAACTGTGGCGCCGCCAGCAAGGCTACGGACGCGGGGGACGCATGAAGATCGAAA
CCGACAAGGCCGAGATCGTCGCCGGAGTGCGCCATTCCCGGACTATCGGCGCTCCCCTCGCCATCATCATCCGTAACAAG
GACTGGCAGAACTGGACCGAAATCCTTCCCGTCGAGGATGCCGGTAGCGGCGCTGACCGCAAACCCGTCACCCGTCCGCG
ACCCGGCCATGCCGACCTTGCCGGAGCCATCAAGTATAACTTCCACGATGCGCGCTACATCCTGGAACGGGCCAGCGCCC
GCGAAACCACCGCCCGCGTCGCCGTCGGCGCCATCGCCAAGGCCCTGCTCGCCGAGTTCGGAATCCAGGTCCTCAGCCAC
GTGATCGCAGTCGGGTCCGTCCGGCTGGAGCGCGCCGCCTCCTGGGACGAACTCGTCGCCCTCAGCCTCCGCGACCAGGT
CCTGCTGGGCTGCGTCGATGCCGAAACCGAAGCCCGCATGAAGGAAGTGGTGGATGAGGCCTACCGCACCGGCGACACCG
TCGGCGGCGTCTTCGAAGTCGTCGCCCGCGGCCTTCCCATCGGCCTCGGCTCCCACGTCACCTGGGATTCGCGCCTCGAT
GGCCGCCTCGCCCAGGCCATCGTCAGCATGCAGGCCGTCAAGGGCGTGGAAGTCGGTTTTGCCGCCGAAGGCGCGGCCAG
TTTTGGTTCCAAAGTGCAGGACACGATCCACTACGATCGCGAGGCACACCACTTCACCCGCGGCGCCAATCGCGCCGGCG
GTATCGAAGGCGGCATGACTAACGGCCAGGACATCCTGGTTCGCGGCATGCTCAAGCCCATCTCCACCCTGCGCCGCCCC
TTGGAATCGGTGGATCTTTTGACCCGCGAACCGTCGCCCGCCGCCTACGAGCGCAGCGACGTGTGCGTGGTCCCGGCGGC
CGGTGTCATTGGCGAAGCCATGGTGGCGATCGTCCTGGCACAGGCCTTTTTGGAAAAGTTCGGCGGCGATTCCCTGACCG
AAACGCGCCGCAATTTCGATAGCTACCTGGAACAGGTGAAGAACTACTAA

Upstream 100 bases:

>100_bases
ATGCACCACAAGAGGAACTTCATCGTCTCGGTCTCCCGTTAGCTTCTACGCACAAAGGCAAGGAAATGTTCGAGTCTGGT
ACCATTAAAATCTTACCTTA

Downstream 100 bases:

>100_bases
TAGCGATATGGTTTATCCGATTGTGAAGTTTGGCGACCCCGTGCTCGAACGCGAGGCCGATACCGTAACTGAGTTCGATA
CTCCGGAACTGCACAAGTTC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLRFETAGESHGECLVATMNGLPAGIPISLETVNRELWRRQQGYGRGGRMKIETDKAEIVAGVRHSRTIGAPLAIIIRNK
DWQNWTEILPVEDAGSGADRKPVTRPRPGHADLAGAIKYNFHDARYILERASARETTARVAVGAIAKALLAEFGIQVLSH
VIAVGSVRLERAASWDELVALSLRDQVLLGCVDAETEARMKEVVDEAYRTGDTVGGVFEVVARGLPIGLGSHVTWDSRLD
GRLAQAIVSMQAVKGVEVGFAAEGAASFGSKVQDTIHYDREAHHFTRGANRAGGIEGGMTNGQDILVRGMLKPISTLRRP
LESVDLLTREPSPAAYERSDVCVVPAAGVIGEAMVAIVLAQAFLEKFGGDSLTETRRNFDSYLEQVKNY

Sequences:

>Translated_389_residues
MLRFETAGESHGECLVATMNGLPAGIPISLETVNRELWRRQQGYGRGGRMKIETDKAEIVAGVRHSRTIGAPLAIIIRNK
DWQNWTEILPVEDAGSGADRKPVTRPRPGHADLAGAIKYNFHDARYILERASARETTARVAVGAIAKALLAEFGIQVLSH
VIAVGSVRLERAASWDELVALSLRDQVLLGCVDAETEARMKEVVDEAYRTGDTVGGVFEVVARGLPIGLGSHVTWDSRLD
GRLAQAIVSMQAVKGVEVGFAAEGAASFGSKVQDTIHYDREAHHFTRGANRAGGIEGGMTNGQDILVRGMLKPISTLRRP
LESVDLLTREPSPAAYERSDVCVVPAAGVIGEAMVAIVLAQAFLEKFGGDSLTETRRNFDSYLEQVKNY
>Mature_389_residues
MLRFETAGESHGECLVATMNGLPAGIPISLETVNRELWRRQQGYGRGGRMKIETDKAEIVAGVRHSRTIGAPLAIIIRNK
DWQNWTEILPVEDAGSGADRKPVTRPRPGHADLAGAIKYNFHDARYILERASARETTARVAVGAIAKALLAEFGIQVLSH
VIAVGSVRLERAASWDELVALSLRDQVLLGCVDAETEARMKEVVDEAYRTGDTVGGVFEVVARGLPIGLGSHVTWDSRLD
GRLAQAIVSMQAVKGVEVGFAAEGAASFGSKVQDTIHYDREAHHFTRGANRAGGIEGGMTNGQDILVRGMLKPISTLRRP
LESVDLLTREPSPAAYERSDVCVVPAAGVIGEAMVAIVLAQAFLEKFGGDSLTETRRNFDSYLEQVKNY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=369, Percent_Identity=35.230352303523, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321290, Length=372, Percent_Identity=31.7204301075269, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SOLUE (Q023V7)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_824018.1
- ProteinModelPortal:   Q023V7
- SMR:   Q023V7
- STRING:   Q023V7
- GeneID:   4429103
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_2745
- NMPDR:   fig|234267.9.peg.2621
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42108; Mature: 42108

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFETAGESHGECLVATMNGLPAGIPISLETVNRELWRRQQGYGRGGRMKIETDKAEIV
CCEECCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
AGVRHSRTIGAPLAIIIRNKDWQNWTEILPVEDAGSGADRKPVTRPRPGHADLAGAIKYN
HHHHHCCCCCCCEEEEEECCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCCCCHHHEEEC
FHDARYILERASARETTARVAVGAIAKALLAEFGIQVLSHVIAVGSVRLERAASWDELVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LSLRDQVLLGCVDAETEARMKEVVDEAYRTGDTVGGVFEVVARGLPIGLGSHVTWDSRLD
HHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
GRLAQAIVSMQAVKGVEVGFAAEGAASFGSKVQDTIHYDREAHHFTRGANRAGGIEGGMT
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCC
NGQDILVRGMLKPISTLRRPLESVDLLTREPSPAAYERSDVCVVPAAGVIGEAMVAIVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHH
QAFLEKFGGDSLTETRRNFDSYLEQVKNY
HHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRFETAGESHGECLVATMNGLPAGIPISLETVNRELWRRQQGYGRGGRMKIETDKAEIV
CCEECCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
AGVRHSRTIGAPLAIIIRNKDWQNWTEILPVEDAGSGADRKPVTRPRPGHADLAGAIKYN
HHHHHCCCCCCCEEEEEECCCCCCHHHEECCCCCCCCCCCCCCCCCCCCCCCCHHHEEEC
FHDARYILERASARETTARVAVGAIAKALLAEFGIQVLSHVIAVGSVRLERAASWDELVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LSLRDQVLLGCVDAETEARMKEVVDEAYRTGDTVGGVFEVVARGLPIGLGSHVTWDSRLD
HHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
GRLAQAIVSMQAVKGVEVGFAAEGAASFGSKVQDTIHYDREAHHFTRGANRAGGIEGGMT
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCC
NGQDILVRGMLKPISTLRRPLESVDLLTREPSPAAYERSDVCVVPAAGVIGEAMVAIVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHH
QAFLEKFGGDSLTETRRNFDSYLEQVKNY
HHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA