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The map label for this gene is kdgR [H]

Identifier: 116621854

GI number: 116621854

Start: 3474444

End: 3475214

Strand: Direct

Name: kdgR [H]

Synonym: Acid_2737

Alternate gene names: 116621854

Gene position: 3474444-3475214 (Clockwise)

Preceding gene: 116621848

Following gene: 116621855

Centisome position: 34.86

GC content: 62.0

Gene sequence:

>771_bases
ATGAGCATGCTTCCGGCGGAGACTTCGGGTGTTCGGGTCCTGCACAAGACGCTCGATATCCTGGAAAAAATCAAGAGCAC
CGAGTCGGGCTACAAGCTGGCCGACCTGGCGCGCAAGGTGGAATTGCCGAAAGCCACCGTGTATCGCATCCTGACCACGC
TCGAAGGGCGCGGCTACCTGGATCGTGCTTCCGATGGCAGTTACCGGATGGCCAAGAAACTCTTCGATCTGCAGCGCACC
GCGTCGCTCGAGCAGACGCTGCATCGCGTTTCCCAGCCCATCATGGAGCGCCTGGTCGCGGCCTGCAAGGAAACCGTGAA
CCTCGGCATACTCGATGCCGGCGAAGTCGTCGTGATCAACACGGTGGAAAGTCCGCAGGCCGTGCGCATGTCATCGAAGA
TCGGCAACCGCCGCTACCTGCACTCCACCGCGATCGGCAAGGTGCTGCTCGGCGGCATGCCCGATAAAGAAGTGCAGCGC
CTGCTCCGTATGAAGGGAATTCCCAAACTCACCGATGAGACCATCACGGCACGGCCCGCGGTGCTGGCGGAAATCCAAAA
GGTGCGCCAGCAGGGCTGGGCACTGGATAACCAGGAAAACGAAATCGAGGGCCGCTGCATCGGGGCGCCGATCGCAGGGC
CCGAGGACACCATAGTCGCCGCGCTCAGCATTTCCGGGCCCGTCTTCCGCATGGATATCGAACGCGCCCGCTCGCTGGTT
CCACACCTGAAGGCGGCATGCGCGGAGATTTCGGCGGCAATCCGCAATTAG

Upstream 100 bases:

>100_bases
ATATAGATCAGATTCCGTACCATAGAATAGGTGCATTTCACCAGCGAGTCAATGAGATCTTCGGCATATTCTGAACCGCG
CTGTACTACAATGTGGAACG

Downstream 100 bases:

>100_bases
GCCATTGCCTATTTAAGAGCGATTGGTCCTATAATCGCTCTATGCGAAATCTGTTGGCGTACTTATTGCTGGTGTCGATG
GTCGCGTTGACGTCCCTCGT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSMLPAETSGVRVLHKTLDILEKIKSTESGYKLADLARKVELPKATVYRILTTLEGRGYLDRASDGSYRMAKKLFDLQRT
ASLEQTLHRVSQPIMERLVAACKETVNLGILDAGEVVVINTVESPQAVRMSSKIGNRRYLHSTAIGKVLLGGMPDKEVQR
LLRMKGIPKLTDETITARPAVLAEIQKVRQQGWALDNQENEIEGRCIGAPIAGPEDTIVAALSISGPVFRMDIERARSLV
PHLKAACAEISAAIRN

Sequences:

>Translated_256_residues
MSMLPAETSGVRVLHKTLDILEKIKSTESGYKLADLARKVELPKATVYRILTTLEGRGYLDRASDGSYRMAKKLFDLQRT
ASLEQTLHRVSQPIMERLVAACKETVNLGILDAGEVVVINTVESPQAVRMSSKIGNRRYLHSTAIGKVLLGGMPDKEVQR
LLRMKGIPKLTDETITARPAVLAEIQKVRQQGWALDNQENEIEGRCIGAPIAGPEDTIVAALSISGPVFRMDIERARSLV
PHLKAACAEISAAIRN
>Mature_255_residues
SMLPAETSGVRVLHKTLDILEKIKSTESGYKLADLARKVELPKATVYRILTTLEGRGYLDRASDGSYRMAKKLFDLQRTA
SLEQTLHRVSQPIMERLVAACKETVNLGILDAGEVVVINTVESPQAVRMSSKIGNRRYLHSTAIGKVLLGGMPDKEVQRL
LRMKGIPKLTDETITARPAVLAEIQKVRQQGWALDNQENEIEGRCIGAPIAGPEDTIVAALSISGPVFRMDIERARSLVP
HLKAACAEISAAIRN

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=223, Percent_Identity=37.219730941704, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=30.2040816326531, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082359, Length=249, Percent_Identity=27.710843373494, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786715, Length=251, Percent_Identity=26.6932270916335, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790752, Length=221, Percent_Identity=27.1493212669683, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789999, Length=248, Percent_Identity=29.0322580645161, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788581, Length=242, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28108; Mature: 27977

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMLPAETSGVRVLHKTLDILEKIKSTESGYKLADLARKVELPKATVYRILTTLEGRGYL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
DRASDGSYRMAKKLFDLQRTASLEQTLHRVSQPIMERLVAACKETVNLGILDAGEVVVIN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEE
TVESPQAVRMSSKIGNRRYLHSTAIGKVLLGGMPDKEVQRLLRMKGIPKLTDETITARPA
ECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHCCHH
VLAEIQKVRQQGWALDNQENEIEGRCIGAPIAGPEDTIVAALSISGPVFRMDIERARSLV
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHH
PHLKAACAEISAAIRN
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMLPAETSGVRVLHKTLDILEKIKSTESGYKLADLARKVELPKATVYRILTTLEGRGYL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
DRASDGSYRMAKKLFDLQRTASLEQTLHRVSQPIMERLVAACKETVNLGILDAGEVVVIN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEEEE
TVESPQAVRMSSKIGNRRYLHSTAIGKVLLGGMPDKEVQRLLRMKGIPKLTDETITARPA
ECCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHCCHH
VLAEIQKVRQQGWALDNQENEIEGRCIGAPIAGPEDTIVAALSISGPVFRMDIERARSLV
HHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHH
PHLKAACAEISAAIRN
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]