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The map label for this gene is xylR [H]

Identifier: 116621796

GI number: 116621796

Start: 3391467

End: 3392630

Strand: Direct

Name: xylR [H]

Synonym: Acid_2678

Alternate gene names: 116621796

Gene position: 3391467-3392630 (Clockwise)

Preceding gene: 116621794

Following gene: 116621797

Centisome position: 34.03

GC content: 64.95

Gene sequence:

>1164_bases
ATGCCGGTAAGCGCCAAGCGGCCCCAAGGGGCTTCTAGCGAAGTGGTTCGCGACATCAACCGCCGGATCGTCCTCAATTT
GGTGCGCACCCGGCAGCCCATTTCGCGCGCCGACCTGGCGCGGGCCTCGGGACTGCAGCGCAGCACTATTTCGCTGATCG
TCGAACAGTTGATCGAGGAGAACTGGGTGCTCGAAGGTCCCACGGGCCGCTTGCCGCGCGGGCGCCGGCCCACGTTCCTT
CGGCTCAATGACGACCGTGTCATCATCGGCGTCGATATCCGTCCTATTCAGACTACGGTCGCGCTCGCCGACGCCAACGG
CAAGTTCACCTCGCAGGAGGTGATGAGCACGCCGGGCGATCCGAAACTCGCCTTGACGCAGTTGATCGCCGCCATCAAGC
GCATCAAGAGCACCTGCCGCGGCAAAATGATCGAGGGCATCGGCATCAGTCTGCCGGGGCGTTTCGACCATTCTTCGAAC
CGCCTCGTGTTCGCCCCGAACCTGAAGTGGACCGATATCGATATCCGCGACCCGATCGTGGAGCAGACCGGGCTCGACGT
CGAACTCGAGAACGCCGCCAACGCCTGTGTGCTGGCCGAGGTCTGGTTCGACCGCGTGCATGAGTGCCGCAACCTTGTCG
TGGTGACCGTTTCCGAGGGCATCGGCACGGGCGTGCTCGCCAACGGCGCCCTGGTGCGCGGACTCAGCGGCATGGCCGGG
GAGTTCGGCCACGTGCCGCTCGATCCCACAGGTCCTACGTGCGGTTGTGGCAGCCGCGGCTGCTGGGAGATCTTCGCCTC
CAACCGCGCGGCCCTGCGCTATTACCTGGAAACCGGGTCCACCGAGACTGGCTTGAGCTTTACAGATCTGCTCAGCCGCG
CCGATCAGGGCGATAGCCGCGCCGAAAAAGCGCTCGACATGATGGCCCACTACCTGGGACGCGGCATGCGCATGATCGTT
GCCGGCCTTGCTCCCGAGCGGATCGTGGTGGTCGGCGACCTGACCCGCTCCTGGCAGCGTTTCGGCAGCGTGATCGAAGC
CGAGATACAGGCCCAGGTCCTTCCCGGAGGCGTGGTCCCCAAGTTGGTCCCGGCCTTCGAAGACGGCATGGCCCGCCTCC
GCGGCACCGTAGCCCTGGTCCTTCAAAAACACTTCAGCGTGTAG

Upstream 100 bases:

>100_bases
TTCCTTATATGCTTGCATGGAACCGGCCGCGCTCTGCTAGGCTATATTGTTTGAGGTTCAAAGCATTCGCATGGATTCCG
CGAGAATGGTGGCTGATGGC

Downstream 100 bases:

>100_bases
TCTCTTCGCCGAGTCTCCCTTTGATTCGCGAGTGCCATCGGGTATAGTTGTAATCCACAACTATATGCCTCGGCCCGCCA
AAATTGAGCCGTACCGAAAC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPVSAKRPQGASSEVVRDINRRIVLNLVRTRQPISRADLARASGLQRSTISLIVEQLIEENWVLEGPTGRLPRGRRPTFL
RLNDDRVIIGVDIRPIQTTVALADANGKFTSQEVMSTPGDPKLALTQLIAAIKRIKSTCRGKMIEGIGISLPGRFDHSSN
RLVFAPNLKWTDIDIRDPIVEQTGLDVELENAANACVLAEVWFDRVHECRNLVVVTVSEGIGTGVLANGALVRGLSGMAG
EFGHVPLDPTGPTCGCGSRGCWEIFASNRAALRYYLETGSTETGLSFTDLLSRADQGDSRAEKALDMMAHYLGRGMRMIV
AGLAPERIVVVGDLTRSWQRFGSVIEAEIQAQVLPGGVVPKLVPAFEDGMARLRGTVALVLQKHFSV

Sequences:

>Translated_387_residues
MPVSAKRPQGASSEVVRDINRRIVLNLVRTRQPISRADLARASGLQRSTISLIVEQLIEENWVLEGPTGRLPRGRRPTFL
RLNDDRVIIGVDIRPIQTTVALADANGKFTSQEVMSTPGDPKLALTQLIAAIKRIKSTCRGKMIEGIGISLPGRFDHSSN
RLVFAPNLKWTDIDIRDPIVEQTGLDVELENAANACVLAEVWFDRVHECRNLVVVTVSEGIGTGVLANGALVRGLSGMAG
EFGHVPLDPTGPTCGCGSRGCWEIFASNRAALRYYLETGSTETGLSFTDLLSRADQGDSRAEKALDMMAHYLGRGMRMIV
AGLAPERIVVVGDLTRSWQRFGSVIEAEIQAQVLPGGVVPKLVPAFEDGMARLRGTVALVLQKHFSV
>Mature_386_residues
PVSAKRPQGASSEVVRDINRRIVLNLVRTRQPISRADLARASGLQRSTISLIVEQLIEENWVLEGPTGRLPRGRRPTFLR
LNDDRVIIGVDIRPIQTTVALADANGKFTSQEVMSTPGDPKLALTQLIAAIKRIKSTCRGKMIEGIGISLPGRFDHSSNR
LVFAPNLKWTDIDIRDPIVEQTGLDVELENAANACVLAEVWFDRVHECRNLVVVTVSEGIGTGVLANGALVRGLSGMAGE
FGHVPLDPTGPTCGCGSRGCWEIFASNRAALRYYLETGSTETGLSFTDLLSRADQGDSRAEKALDMMAHYLGRGMRMIVA
GLAPERIVVVGDLTRSWQRFGSVIEAEIQAQVLPGGVVPKLVPAFEDGMARLRGTVALVLQKHFSV

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=26.7657992565056, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI190014632, Length=269, Percent_Identity=26.7657992565056, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=26.7657992565056, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=26.7657992565056, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786891, Length=359, Percent_Identity=25.9052924791086, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787878, Length=356, Percent_Identity=25.8426966292135, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787363, Length=313, Percent_Identity=25.2396166134185, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082127, Length=335, Percent_Identity=22.089552238806, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081733, Length=273, Percent_Identity=26.7399267399267, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42052; Mature: 41921

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSAKRPQGASSEVVRDINRRIVLNLVRTRQPISRADLARASGLQRSTISLIVEQLIEE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHC
NWVLEGPTGRLPRGRRPTFLRLNDDRVIIGVDIRPIQTTVALADANGKFTSQEVMSTPGD
CCEEECCCCCCCCCCCCCEEEECCCEEEEEECCEEEEEEEEEECCCCCCCHHHHHCCCCC
PKLALTQLIAAIKRIKSTCRGKMIEGIGISLPGRFDHSSNRLVFAPNLKWTDIDIRDPIV
CHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCHH
EQTGLDVELENAANACVLAEVWFDRVHECRNLVVVTVSEGIGTGVLANGALVRGLSGMAG
HHCCCCEEECCCCCEEEHHHHHHHHHHHHCCEEEEEECCCCCCCHHCCCHHHHCCCCCCC
EFGHVPLDPTGPTCGCGSRGCWEIFASNRAALRYYLETGSTETGLSFTDLLSRADQGDSR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCHHH
AEKALDMMAHYLGRGMRMIVAGLAPERIVVVGDLTRSWQRFGSVIEAEIQAQVLPGGVVP
HHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHEEECCCCCHH
KLVPAFEDGMARLRGTVALVLQKHFSV
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVSAKRPQGASSEVVRDINRRIVLNLVRTRQPISRADLARASGLQRSTISLIVEQLIEE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHC
NWVLEGPTGRLPRGRRPTFLRLNDDRVIIGVDIRPIQTTVALADANGKFTSQEVMSTPGD
CCEEECCCCCCCCCCCCCEEEECCCEEEEEECCEEEEEEEEEECCCCCCCHHHHHCCCCC
PKLALTQLIAAIKRIKSTCRGKMIEGIGISLPGRFDHSSNRLVFAPNLKWTDIDIRDPIV
CHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCHH
EQTGLDVELENAANACVLAEVWFDRVHECRNLVVVTVSEGIGTGVLANGALVRGLSGMAG
HHCCCCEEECCCCCEEEHHHHHHHHHHHHCCEEEEEECCCCCCCHHCCCHHHHCCCCCCC
EFGHVPLDPTGPTCGCGSRGCWEIFASNRAALRYYLETGSTETGLSFTDLLSRADQGDSR
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCHHH
AEKALDMMAHYLGRGMRMIVAGLAPERIVVVGDLTRSWQRFGSVIEAEIQAQVLPGGVVP
HHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHEEECCCCCHH
KLVPAFEDGMARLRGTVALVLQKHFSV
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]