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The map label for this gene is yieG [C]

Identifier: 116621674

GI number: 116621674

Start: 3235694

End: 3237016

Strand: Direct

Name: yieG [C]

Synonym: Acid_2556

Alternate gene names: 116621674

Gene position: 3235694-3237016 (Clockwise)

Preceding gene: 116621673

Following gene: 116621675

Centisome position: 32.47

GC content: 61.68

Gene sequence:

>1323_bases
ATGGCCTTCATGCCGCTGCGTGCCACGCTGGAGGAGTACTTTGAATTCAAGCCGCTCGGCGCCGAGTGGAAGACCGAGAT
ACTGGCCGGCTTCACCACCTTCATGACGATGGCGTACATCGTCTTCGTGAATCCCGCAATCCTGCACGAGACGGGTATGC
CGCTGGCGGCGGTCACTGCCGCCACCTGCCTTTCGGCGGCCGCGGGAAGTTTCCTGATGGGCGGCTTCGCGAAATACCCG
ATCGCGCTGGCTCCCGGGATGGGGCTCAATGCGTACTTCACGTACGCGGTGGTGAAGGGGATGGGTGTGCCGTGGCAGGC
CGCACTGGGAGCGGTCTTCATTTCCGGTGTCGCGTTTCTGCTGCTCACCGCGCTCGGTGTGCGGCAGTTGATTGTCTCGG
CGATTCCGCACGAGCTTTATGCGGCGGTGGCGGCGGGCGTAGGGCTCTTCATCGCGTTCATCGGGTTTCGCAATTCCGGC
ATTATCGTGCCGCATCCGGCGACCACGGTGACGCTCGGAAACCTGCGCGATCCGGCTTCTGCGCTGGCGCTCTTCGGATT
GCTGCTGATTGCGGCGCTGCTGGCTTGGAGGGTGCGCGCGGCGATGCTGATCGGGATTCTGGCGACTACGCTGGTGGGAT
TAGTCACGGGTGTCGCCAAGTGGGCGCCGCAATCTTATAGCCTGGGCGATCTTTCGGCCACCGCAGGTAAGTTGGACATC
GGCGGCGCGGTACGGCTCGGCTTCGTGGAGATTATCTTTGTGTTTCTGTTCATCGATTTATTCGATAACATCGGCACCCT
GGTCGCGGTGGGCAAGAAGGCGAATCTATTCGACGAGGCGCGCCAGATCCCGCGGCTCAACCGCATTCTGTTTTCTGATG
CGATCGCCACCATCGTGGGGGCGTTCTCCGGTACATCGACGGTAGTGAGTTACATCGAAAGCGCGGCGGGCGTAGCGGTG
GGCGGCCGCACCGGGGTCACCGCGATCGTCACTGGGATGTTGTTTCTCGTGGCGTTGTTCGTCGCGCCGGTGGTGGGAGC
GATCCCCGCCGCCGCCACCGCTCCGGCGTTGATCGTGGTGGGCAGCATGATGGTTTCCGTGGTGGGCGAGATCGCGTGGA
GCGATCCGGAGATCGCCATCCCGGCGTTCCTGACAATGATGACGATCCCGTTGACTTTCAGTATTGCCAACGGCCTGGCA
TTCGGTTTCACGGCATATAGCCTGCTCAAGGTATCGCGCGGTAAGTTCCGCGAAGTGAATTGGTTCGTGTATCTGCTGAC
GGCGTTGTTTATCGCTCGCTTCCTCTATCTCGGGCGGGGATAA

Upstream 100 bases:

>100_bases
GGTGAGCGTAGTGGATAAGACTGCGCCGCCCGGCGCGCCGCGGACCGCCAGCCGCTTCATCGATTTCCATCTACGCGACT
GAAGGCGCCGGCGGGTTAAG

Downstream 100 bases:

>100_bases
GATCGCGGTTTGAGATCGCTTCCTGACGGTCGCGGTTCGCGGCGCGGCCGCCGGTAACTCCGGGCCGCAGCGCACTGCGA
GGGTTAGGGAACGACCCAGG

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAFMPLRATLEEYFEFKPLGAEWKTEILAGFTTFMTMAYIVFVNPAILHETGMPLAAVTAATCLSAAAGSFLMGGFAKYP
IALAPGMGLNAYFTYAVVKGMGVPWQAALGAVFISGVAFLLLTALGVRQLIVSAIPHELYAAVAAGVGLFIAFIGFRNSG
IIVPHPATTVTLGNLRDPASALALFGLLLIAALLAWRVRAAMLIGILATTLVGLVTGVAKWAPQSYSLGDLSATAGKLDI
GGAVRLGFVEIIFVFLFIDLFDNIGTLVAVGKKANLFDEARQIPRLNRILFSDAIATIVGAFSGTSTVVSYIESAAGVAV
GGRTGVTAIVTGMLFLVALFVAPVVGAIPAAATAPALIVVGSMMVSVVGEIAWSDPEIAIPAFLTMMTIPLTFSIANGLA
FGFTAYSLLKVSRGKFREVNWFVYLLTALFIARFLYLGRG

Sequences:

>Translated_440_residues
MAFMPLRATLEEYFEFKPLGAEWKTEILAGFTTFMTMAYIVFVNPAILHETGMPLAAVTAATCLSAAAGSFLMGGFAKYP
IALAPGMGLNAYFTYAVVKGMGVPWQAALGAVFISGVAFLLLTALGVRQLIVSAIPHELYAAVAAGVGLFIAFIGFRNSG
IIVPHPATTVTLGNLRDPASALALFGLLLIAALLAWRVRAAMLIGILATTLVGLVTGVAKWAPQSYSLGDLSATAGKLDI
GGAVRLGFVEIIFVFLFIDLFDNIGTLVAVGKKANLFDEARQIPRLNRILFSDAIATIVGAFSGTSTVVSYIESAAGVAV
GGRTGVTAIVTGMLFLVALFVAPVVGAIPAAATAPALIVVGSMMVSVVGEIAWSDPEIAIPAFLTMMTIPLTFSIANGLA
FGFTAYSLLKVSRGKFREVNWFVYLLTALFIARFLYLGRG
>Mature_439_residues
AFMPLRATLEEYFEFKPLGAEWKTEILAGFTTFMTMAYIVFVNPAILHETGMPLAAVTAATCLSAAAGSFLMGGFAKYPI
ALAPGMGLNAYFTYAVVKGMGVPWQAALGAVFISGVAFLLLTALGVRQLIVSAIPHELYAAVAAGVGLFIAFIGFRNSGI
IVPHPATTVTLGNLRDPASALALFGLLLIAALLAWRVRAAMLIGILATTLVGLVTGVAKWAPQSYSLGDLSATAGKLDIG
GAVRLGFVEIIFVFLFIDLFDNIGTLVAVGKKANLFDEARQIPRLNRILFSDAIATIVGAFSGTSTVVSYIESAAGVAVG
GRTGVTAIVTGMLFLVALFVAPVVGAIPAAATAPALIVVGSMMVSVVGEIAWSDPEIAIPAFLTMMTIPLTFSIANGLAF
GFTAYSLLKVSRGKFREVNWFVYLLTALFIARFLYLGRG

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=431, Percent_Identity=42.4593967517401, Blast_Score=352, Evalue=2e-98,
Organism=Escherichia coli, GI87082309, Length=422, Percent_Identity=43.1279620853081, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1790499, Length=421, Percent_Identity=34.6793349168646, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=34.4827586206897, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46129; Mature: 45998

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFMPLRATLEEYFEFKPLGAEWKTEILAGFTTFMTMAYIVFVNPAILHETGMPLAAVTA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHH
ATCLSAAAGSFLMGGFAKYPIALAPGMGLNAYFTYAVVKGMGVPWQAALGAVFISGVAFL
HHHHHHHHHHHHHCCHHHCCEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LLTALGVRQLIVSAIPHELYAAVAAGVGLFIAFIGFRNSGIIVPHPATTVTLGNLRDPAS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCHHH
ALALFGLLLIAALLAWRVRAAMLIGILATTLVGLVTGVAKWAPQSYSLGDLSATAGKLDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GGAVRLGFVEIIFVFLFIDLFDNIGTLVAVGKKANLFDEARQIPRLNRILFSDAIATIVG
CCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
AFSGTSTVVSYIESAAGVAVGGRTGVTAIVTGMLFLVALFVAPVVGAIPAAATAPALIVV
HCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GSMMVSVVGEIAWSDPEIAIPAFLTMMTIPLTFSIANGLAFGFTAYSLLKVSRGKFREVN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
WFVYLLTALFIARFLYLGRG
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFMPLRATLEEYFEFKPLGAEWKTEILAGFTTFMTMAYIVFVNPAILHETGMPLAAVTA
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHH
ATCLSAAAGSFLMGGFAKYPIALAPGMGLNAYFTYAVVKGMGVPWQAALGAVFISGVAFL
HHHHHHHHHHHHHCCHHHCCEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LLTALGVRQLIVSAIPHELYAAVAAGVGLFIAFIGFRNSGIIVPHPATTVTLGNLRDPAS
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCCHHH
ALALFGLLLIAALLAWRVRAAMLIGILATTLVGLVTGVAKWAPQSYSLGDLSATAGKLDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GGAVRLGFVEIIFVFLFIDLFDNIGTLVAVGKKANLFDEARQIPRLNRILFSDAIATIVG
CCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHH
AFSGTSTVVSYIESAAGVAVGGRTGVTAIVTGMLFLVALFVAPVVGAIPAAATAPALIVV
HCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GSMMVSVVGEIAWSDPEIAIPAFLTMMTIPLTFSIANGLAFGFTAYSLLKVSRGKFREVN
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
WFVYLLTALFIARFLYLGRG
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]