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The map label for this gene is macB [H]

Identifier: 116621574

GI number: 116621574

Start: 3119977

End: 3122376

Strand: Reverse

Name: macB [H]

Synonym: Acid_2456

Alternate gene names: 116621574

Gene position: 3122376-3119977 (Counterclockwise)

Preceding gene: 116621575

Following gene: 116621573

Centisome position: 31.33

GC content: 67.04

Gene sequence:

>2400_bases
GTGGCAATTCTCACGATCGGGATCGGCATCGGCGCCAACACCACGGTGTTCAGCTGGATGCACGGGCTGCTGCTGAATCC
GCTCCCGGGGGCGGCGGAGCCGGAGCGCGTGGTGATGGTGGAGAGCGTGGCGGCGAATGGCGATCCGCTGACGACGTCTT
ACCTGGACTACCGGGATTTCCGGGACCACCTGCGCTCTTTTGAGAACCTCAGCCTGTTTGCTCCCGCGGTATTTGCGGTC
GGGGACGATGAGCGAACGCAGCGCGTGTGGGGTGAGTTCGTATCGGGCAACTACTTCGACGCGATGCGGGTGCAGGCGGC
AGCGGGACGGTTCTTTTCGGGGGCGGAGCGCGATGATGCGCAGAACGTGCACTCCGTGCTGGTGATCAGCCACGCGTTTT
GGAAGGCGCGTTACAACCTGAGCGAGTCGGCAATCGGCGCCACGGTGCGGATTAACCGCACTCCGTTTACGATCATCGGC
GTGGCGGCACCGGCGTTCCATGGCTCGCAAAGCGGGTTGAGTTTCGACCTGTGGGTTCCGGCGACGATGTACGGGCAGGT
GACGCACACGGGCACCTGGATGCTGCGCGACCGCAATACGCGCAACTTCACGATGCTGGCGCGGCTGAGGCCGGCCGTGA
CGATCGCGCAGGCGCGGGAGGAAACGCGCGCCCTGGCGGGCCGGATGGCGGTGCTGGACGCGGACACGAATCAGGGTGTG
GGCGCGGAGGTGCTGCCGGTGTGGAAAGGGCACTTCACGCCGCAAGCGGTGATCCTGGCGCCGATCTCGATTCTGATGGG
TGCGGCCGGGCTCTTTCTTTTGATCGTGTGTGCCAATGTGGCGAACCTGCTGCTGGCGCGGGCAACCGGGCGGCGGAAGG
AATTCAGCATCCGGCTGGCGCTGGGTGCGCGTCCGGCGCGGCTGGTGCGGCAACTGCTGACGGAGACGCTGCTGCTGGCG
GTGGCGGGAGGCGCGGCGGGACTGGCGATCGCGAACTGGCTGGGCGGGTCTTTGCGCTGGTTATTGCCCCGAGTGGCGGC
GCCGGCGATTCTGCAGCCGGAACTCGACCCCGGCGTATTGCTGTTCACGACGGCCGCGGCATTCGCGGTGGCGATTCTGG
CCGGCACGGGTCCGGCGCTGACGGCGGCGCGCGCCAACGTCAACGACGTCTTGAAGCAGGGAGGACGGAGCGGAGCGTCG
GTTCCATCTGGCCGTTTGCGCGGGCCGCTGGTGGTGGGCGAAGTCGCGCTCGCGGTGATCGCACTGGTGGGCGGCGGACT
GCTGATGAAAAGCTTCGCACAGGCTCGCTCGATCCATCCGGGTTTCACGGCCGAGGGAGTGGCGCTGACGCGCTTCGACC
TCTCGTCGGCGGGTTACAACGCGCAGCAGGCCGACGCGTTTTGCCGGCGGCTGCGGGAGAGTCTGGAGCGGACTCCGGGT
GTGACGGCGGTGAGCTACGACGATTCGCCGCCGCTGGGATTCCAGGGCGGGAACTGGGAGCCGATCGAGGTAGAGGGCTA
TGTCGCGGGGCGCAGCGAGAACATGAAGATCAATCGCGACATGATCTCGCCGGGGTACTTCGAGCTGATGAAGATCCCGC
TCTTGGCGGGGCGGGATTTCGACCTGGGCGATACGGCGACGAAGCTGCACAACGATCCGGCGTACCGGAAGGTAATGATA
GTGAACCAGGAGTTCGCGCGGCGGTTCTTTGCGGGGCGCGACCCGATCGGACGCAAGGTGCGCGGATGGGGCGAATGGTT
CACGGTGGTGGGCGTCGCGGGGAATATCAAGTATCAACGGCTCACGGAGGGACCGCGGCCATTCGTCTATATTCCTATCC
GGCAGGTCTACCGGCCGGAGTACGGGCTGACGTTCCACGTGCGCACGGTGGGACCAGTGGCGGAGGCGATCGCGGCGATT
CGCCGCGAGGCGGCTGCGATCGACCGGGGGCTGATGATCTTCGACAGCATGGAGATGAAGGAGTACATTTCGGCGTCGTT
GTACGGGCAGAAGGTCGGAGCGATTCTGCTGAATGTGCTGGGCGGGCTGGGACTGCTGATGGCGGCGCTGGGGCTGTACA
GCGTGATGGCCTACTCGGTGGCGCAGCGCGAGGCGGAGATCGGCATCCGGATGGCGATGGGCGCCAAGCCGCGGGATATG
ATGCTGCTGGTGCTGCGGCAAGGGCTGGGGTTCGCGATGGCGGGACTGGCGTTGGGAGCGCTGGCGTCGGCGGCGCTGGG
GCGGGTGTTAGCGGCCGTGCTGGTCTCGGTGAGCCCGGCCGACCCTGGCGTTTACGCAGGGGCGGCAGCGTTCACGGTCG
CGGTGGCGGTGTTCTCGGCGGGGATACCGGCGTGGCGGGCGCTGCGGGTGGATCCGGTGGTGGCGCTGCGCTCCGAGTAG

Upstream 100 bases:

>100_bases
GAATAGCGCGTGCGGTTCGACCCAGGCGAATATGAACACATTCAGCCAGGACCTTCGTTATGCCCTGCGTGGCCTTTCCC
GGAACCGGGGATTCACCGCA

Downstream 100 bases:

>100_bases
AGATGTAGATCGCTCCCTCACGGTCGCGGTTCGCTGTGCGGACCGAGGAGTTTGCGGAGCAGATCGTCGCCATTTTCGGT
GTCGTCGGGGAGGCTGTGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 799; Mature: 798

Protein sequence:

>799_residues
MAILTIGIGIGANTTVFSWMHGLLLNPLPGAAEPERVVMVESVAANGDPLTTSYLDYRDFRDHLRSFENLSLFAPAVFAV
GDDERTQRVWGEFVSGNYFDAMRVQAAAGRFFSGAERDDAQNVHSVLVISHAFWKARYNLSESAIGATVRINRTPFTIIG
VAAPAFHGSQSGLSFDLWVPATMYGQVTHTGTWMLRDRNTRNFTMLARLRPAVTIAQAREETRALAGRMAVLDADTNQGV
GAEVLPVWKGHFTPQAVILAPISILMGAAGLFLLIVCANVANLLLARATGRRKEFSIRLALGARPARLVRQLLTETLLLA
VAGGAAGLAIANWLGGSLRWLLPRVAAPAILQPELDPGVLLFTTAAAFAVAILAGTGPALTAARANVNDVLKQGGRSGAS
VPSGRLRGPLVVGEVALAVIALVGGGLLMKSFAQARSIHPGFTAEGVALTRFDLSSAGYNAQQADAFCRRLRESLERTPG
VTAVSYDDSPPLGFQGGNWEPIEVEGYVAGRSENMKINRDMISPGYFELMKIPLLAGRDFDLGDTATKLHNDPAYRKVMI
VNQEFARRFFAGRDPIGRKVRGWGEWFTVVGVAGNIKYQRLTEGPRPFVYIPIRQVYRPEYGLTFHVRTVGPVAEAIAAI
RREAAAIDRGLMIFDSMEMKEYISASLYGQKVGAILLNVLGGLGLLMAALGLYSVMAYSVAQREAEIGIRMAMGAKPRDM
MLLVLRQGLGFAMAGLALGALASAALGRVLAAVLVSVSPADPGVYAGAAAFTVAVAVFSAGIPAWRALRVDPVVALRSE

Sequences:

>Translated_799_residues
MAILTIGIGIGANTTVFSWMHGLLLNPLPGAAEPERVVMVESVAANGDPLTTSYLDYRDFRDHLRSFENLSLFAPAVFAV
GDDERTQRVWGEFVSGNYFDAMRVQAAAGRFFSGAERDDAQNVHSVLVISHAFWKARYNLSESAIGATVRINRTPFTIIG
VAAPAFHGSQSGLSFDLWVPATMYGQVTHTGTWMLRDRNTRNFTMLARLRPAVTIAQAREETRALAGRMAVLDADTNQGV
GAEVLPVWKGHFTPQAVILAPISILMGAAGLFLLIVCANVANLLLARATGRRKEFSIRLALGARPARLVRQLLTETLLLA
VAGGAAGLAIANWLGGSLRWLLPRVAAPAILQPELDPGVLLFTTAAAFAVAILAGTGPALTAARANVNDVLKQGGRSGAS
VPSGRLRGPLVVGEVALAVIALVGGGLLMKSFAQARSIHPGFTAEGVALTRFDLSSAGYNAQQADAFCRRLRESLERTPG
VTAVSYDDSPPLGFQGGNWEPIEVEGYVAGRSENMKINRDMISPGYFELMKIPLLAGRDFDLGDTATKLHNDPAYRKVMI
VNQEFARRFFAGRDPIGRKVRGWGEWFTVVGVAGNIKYQRLTEGPRPFVYIPIRQVYRPEYGLTFHVRTVGPVAEAIAAI
RREAAAIDRGLMIFDSMEMKEYISASLYGQKVGAILLNVLGGLGLLMAALGLYSVMAYSVAQREAEIGIRMAMGAKPRDM
MLLVLRQGLGFAMAGLALGALASAALGRVLAAVLVSVSPADPGVYAGAAAFTVAVAVFSAGIPAWRALRVDPVVALRSE
>Mature_798_residues
AILTIGIGIGANTTVFSWMHGLLLNPLPGAAEPERVVMVESVAANGDPLTTSYLDYRDFRDHLRSFENLSLFAPAVFAVG
DDERTQRVWGEFVSGNYFDAMRVQAAAGRFFSGAERDDAQNVHSVLVISHAFWKARYNLSESAIGATVRINRTPFTIIGV
AAPAFHGSQSGLSFDLWVPATMYGQVTHTGTWMLRDRNTRNFTMLARLRPAVTIAQAREETRALAGRMAVLDADTNQGVG
AEVLPVWKGHFTPQAVILAPISILMGAAGLFLLIVCANVANLLLARATGRRKEFSIRLALGARPARLVRQLLTETLLLAV
AGGAAGLAIANWLGGSLRWLLPRVAAPAILQPELDPGVLLFTTAAAFAVAILAGTGPALTAARANVNDVLKQGGRSGASV
PSGRLRGPLVVGEVALAVIALVGGGLLMKSFAQARSIHPGFTAEGVALTRFDLSSAGYNAQQADAFCRRLRESLERTPGV
TAVSYDDSPPLGFQGGNWEPIEVEGYVAGRSENMKINRDMISPGYFELMKIPLLAGRDFDLGDTATKLHNDPAYRKVMIV
NQEFARRFFAGRDPIGRKVRGWGEWFTVVGVAGNIKYQRLTEGPRPFVYIPIRQVYRPEYGLTFHVRTVGPVAEAIAAIR
REAAAIDRGLMIFDSMEMKEYISASLYGQKVGAILLNVLGGLGLLMAALGLYSVMAYSVAQREAEIGIRMAMGAKPRDMM
LLVLRQGLGFAMAGLALGALASAALGRVLAAVLVSVSPADPGVYAGAAAFTVAVAVFSAGIPAWRALRVDPVVALRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=302, Percent_Identity=25.8278145695364, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 85514; Mature: 85383

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILTIGIGIGANTTVFSWMHGLLLNPLPGAAEPERVVMVESVAANGDPLTTSYLDYRDF
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEHHHHHHHH
RDHLRSFENLSLFAPAVFAVGDDERTQRVWGEFVSGNYFDAMRVQAAAGRFFSGAERDDA
HHHHHHHCCCEEECCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCH
QNVHSVLVISHAFWKARYNLSESAIGATVRINRTPFTIIGVAAPAFHGSQSGLSFDLWVP
HHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCEEEEEEC
ATMYGQVTHTGTWMLRDRNTRNFTMLARLRPAVTIAQAREETRALAGRMAVLDADTNQGV
HHHCCCEEECEEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHHHHHCCEEEEECCCCCCC
GAEVLPVWKGHFTPQAVILAPISILMGAAGLFLLIVCANVANLLLARATGRRKEFSIRLA
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
LGARPARLVRQLLTETLLLAVAGGAAGLAIANWLGGSLRWLLPRVAAPAILQPELDPGVL
ECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCEECCCCCCCEE
LFTTAAAFAVAILAGTGPALTAARANVNDVLKQGGRSGASVPSGRLRGPLVVGEVALAVI
EHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALVGGGLLMKSFAQARSIHPGFTAEGVALTRFDLSSAGYNAQQADAFCRRLRESLERTPG
HHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
VTAVSYDDSPPLGFQGGNWEPIEVEGYVAGRSENMKINRDMISPGYFELMKIPLLAGRDF
CEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCEECCCCCCCCHHHHHHHHHCCCCCC
DLGDTATKLHNDPAYRKVMIVNQEFARRFFAGRDPIGRKVRGWGEWFTVVGVAGNIKYQR
CCCCHHHHHCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEEEE
LTEGPRPFVYIPIRQVYRPEYGLTFHVRTVGPVAEAIAAIRREAAAIDRGLMIFDSMEMK
CCCCCCCEEEEEHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECHHHH
EYISASLYGQKVGAILLNVLGGLGLLMAALGLYSVMAYSVAQREAEIGIRMAMGAKPRDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHH
MLLVLRQGLGFAMAGLALGALASAALGRVLAAVLVSVSPADPGVYAGAAAFTVAVAVFSA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
GIPAWRALRVDPVVALRSE
CCCHHHEEECCCEEEECCC
>Mature Secondary Structure 
AILTIGIGIGANTTVFSWMHGLLLNPLPGAAEPERVVMVESVAANGDPLTTSYLDYRDF
EEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEHHHHHHHH
RDHLRSFENLSLFAPAVFAVGDDERTQRVWGEFVSGNYFDAMRVQAAAGRFFSGAERDDA
HHHHHHHCCCEEECCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCH
QNVHSVLVISHAFWKARYNLSESAIGATVRINRTPFTIIGVAAPAFHGSQSGLSFDLWVP
HHHHHHHHHHHHHHHHHCCCCHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCEEEEEEC
ATMYGQVTHTGTWMLRDRNTRNFTMLARLRPAVTIAQAREETRALAGRMAVLDADTNQGV
HHHCCCEEECEEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHHHHHCCEEEEECCCCCCC
GAEVLPVWKGHFTPQAVILAPISILMGAAGLFLLIVCANVANLLLARATGRRKEFSIRLA
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
LGARPARLVRQLLTETLLLAVAGGAAGLAIANWLGGSLRWLLPRVAAPAILQPELDPGVL
ECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCEECCCCCCCEE
LFTTAAAFAVAILAGTGPALTAARANVNDVLKQGGRSGASVPSGRLRGPLVVGEVALAVI
EHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALVGGGLLMKSFAQARSIHPGFTAEGVALTRFDLSSAGYNAQQADAFCRRLRESLERTPG
HHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
VTAVSYDDSPPLGFQGGNWEPIEVEGYVAGRSENMKINRDMISPGYFELMKIPLLAGRDF
CEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCEECCCCCCCCHHHHHHHHHCCCCCC
DLGDTATKLHNDPAYRKVMIVNQEFARRFFAGRDPIGRKVRGWGEWFTVVGVAGNIKYQR
CCCCHHHHHCCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEEEE
LTEGPRPFVYIPIRQVYRPEYGLTFHVRTVGPVAEAIAAIRREAAAIDRGLMIFDSMEMK
CCCCCCCEEEEEHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEECHHHH
EYISASLYGQKVGAILLNVLGGLGLLMAALGLYSVMAYSVAQREAEIGIRMAMGAKPRDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHH
MLLVLRQGLGFAMAGLALGALASAALGRVLAAVLVSVSPADPGVYAGAAAFTVAVAVFSA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHC
GIPAWRALRVDPVVALRSE
CCCHHHEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA