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The map label for this gene is yogA [H]

Identifier: 116621558

GI number: 116621558

Start: 3102555

End: 3103583

Strand: Direct

Name: yogA [H]

Synonym: Acid_2440

Alternate gene names: 116621558

Gene position: 3102555-3103583 (Clockwise)

Preceding gene: 116621554

Following gene: 116621559

Centisome position: 31.13

GC content: 62.0

Gene sequence:

>1029_bases
ATGAAAGTCGCACGGATTCACCAGCACGGCGGCCCTGAAGTGCTCGTCTACGAGGATGTTCCCGAGCCGAAGATCAAAGC
CAATCAGGTGCTCATTCGCGTCCGCGCCTGCGCCTTGAACCACCTGGATCTCTTCGTCCGCGCCGGAATCCCGGGGATGA
AGTTCTCCATGCCCCACGTGCTGGGCAGCGATATTGCGGGTGAAGTCGTAGAGGTCGGCGAACTCTGCGAGCGCGTCAAG
CCGGGCTGGCGCGTGCTTCTGGCCCCCGGTGTCAGCTGCCGCCAGTGCGAGCAGTGCCTCTCCGGCAAGGACAACTTCTG
CCGCAAGTTCACCAATCTCGGCTACGGCGTGGATGGCGGCAATACGGAACTCCTTGCCGTTTCCGAGTACAGCGTCATTC
AGATCCCCGACGATATGAGCTTCGAGGATGCCGCCGCAGCCCCGCTGGTCTTCCTCACCGCCTGGCACATGCTGATGAGC
CGCGCCCGCCTGCAGGCCGGCGAAGACGTGCTCGTGCTTTCCGCCTCCAGCGGCGTGGGCACGGCCGCCATCCAGATTGC
GAAATTATTCCACTGCCGCGTGATCGCGACCGCGGGTAATGAACAGAAACTCGCCAAGGCGCGCGAACTCGGCGCGGACC
ATGTGATCGATCACTACCAGCAGGATATTTCCGCCGAGGTCAGAAAATTCACCGGCAAGCGCGGCGTGGACGTGGTCGTC
GAGCATGTGGGCCTCGCCACCTGGCAGAAGAGCCTCGAATCCCTCGCGCTGGGAGGACGCCTGATTACCTGCGGCGCCAC
CACCGGCTACGACGCGCGCGTCGATCTGCGCTTCCTCTTCAGCAAACAGTGGAGCCTGCTCGGGTCCTTCATGGGAACTC
TCGGCGAACTCCACCAGGTATTGAAATTCGTCTTCCGCAAACAACTGCACCCCGTCATCGATCGGGCGTTTCCGCTCTCC
GGGATCGCCGAAGCTCACCGCTATCTGGAAAACAAGGAGCAGTTCGGCAAAGTGATCCTCACGGTATGA

Upstream 100 bases:

>100_bases
AGAAGCCAGTTTCTTGCTTCTCTGCGTTACTCTGCGGCTCTGCGTCTCTGCGAGAAATATTCTTTCGGCCCGTCCAGCCC
GCCCGTGCTAGCCTTTCCTC

Downstream 100 bases:

>100_bases
GTCCAACAATGATTCTTGGCCTCGTGGTACTGGCCGCTTCGTGGCTCGCGTGGTTCTGGCCGTTCGCTTTCCGCGCTCCG
CACAATCAGCGGCGGCCCTC

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKVARIHQHGGPEVLVYEDVPEPKIKANQVLIRVRACALNHLDLFVRAGIPGMKFSMPHVLGSDIAGEVVEVGELCERVK
PGWRVLLAPGVSCRQCEQCLSGKDNFCRKFTNLGYGVDGGNTELLAVSEYSVIQIPDDMSFEDAAAAPLVFLTAWHMLMS
RARLQAGEDVLVLSASSGVGTAAIQIAKLFHCRVIATAGNEQKLAKARELGADHVIDHYQQDISAEVRKFTGKRGVDVVV
EHVGLATWQKSLESLALGGRLITCGATTGYDARVDLRFLFSKQWSLLGSFMGTLGELHQVLKFVFRKQLHPVIDRAFPLS
GIAEAHRYLENKEQFGKVILTV

Sequences:

>Translated_342_residues
MKVARIHQHGGPEVLVYEDVPEPKIKANQVLIRVRACALNHLDLFVRAGIPGMKFSMPHVLGSDIAGEVVEVGELCERVK
PGWRVLLAPGVSCRQCEQCLSGKDNFCRKFTNLGYGVDGGNTELLAVSEYSVIQIPDDMSFEDAAAAPLVFLTAWHMLMS
RARLQAGEDVLVLSASSGVGTAAIQIAKLFHCRVIATAGNEQKLAKARELGADHVIDHYQQDISAEVRKFTGKRGVDVVV
EHVGLATWQKSLESLALGGRLITCGATTGYDARVDLRFLFSKQWSLLGSFMGTLGELHQVLKFVFRKQLHPVIDRAFPLS
GIAEAHRYLENKEQFGKVILTV
>Mature_342_residues
MKVARIHQHGGPEVLVYEDVPEPKIKANQVLIRVRACALNHLDLFVRAGIPGMKFSMPHVLGSDIAGEVVEVGELCERVK
PGWRVLLAPGVSCRQCEQCLSGKDNFCRKFTNLGYGVDGGNTELLAVSEYSVIQIPDDMSFEDAAAAPLVFLTAWHMLMS
RARLQAGEDVLVLSASSGVGTAAIQIAKLFHCRVIATAGNEQKLAKARELGADHVIDHYQQDISAEVRKFTGKRGVDVVV
EHVGLATWQKSLESLALGGRLITCGATTGYDARVDLRFLFSKQWSLLGSFMGTLGELHQVLKFVFRKQLHPVIDRAFPLS
GIAEAHRYLENKEQFGKVILTV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=348, Percent_Identity=30.4597701149425, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI13236495, Length=348, Percent_Identity=30.4597701149425, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI22538446, Length=362, Percent_Identity=30.6629834254144, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI22538444, Length=362, Percent_Identity=30.6629834254144, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI194239676, Length=348, Percent_Identity=27.8735632183908, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI18379349, Length=336, Percent_Identity=26.7857142857143, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI47519420, Length=379, Percent_Identity=25.065963060686, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24308257, Length=356, Percent_Identity=27.247191011236, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=32.6315789473684, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI41872631, Length=170, Percent_Identity=34.1176470588235, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI67078404, Length=300, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI34577061, Length=360, Percent_Identity=28.3333333333333, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI156627571, Length=335, Percent_Identity=25.6716417910448, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI28557745, Length=282, Percent_Identity=28.0141843971631, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI67078406, Length=272, Percent_Identity=27.5735294117647, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI71565152, Length=377, Percent_Identity=24.6684350132626, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4501939, Length=369, Percent_Identity=26.2872628726287, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI156523966, Length=369, Percent_Identity=26.2872628726287, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4501933, Length=360, Percent_Identity=27.2222222222222, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790485, Length=346, Percent_Identity=28.6127167630058, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081918, Length=318, Percent_Identity=26.7295597484277, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790045, Length=334, Percent_Identity=26.9461077844311, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788073, Length=275, Percent_Identity=30.9090909090909, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI226510992, Length=336, Percent_Identity=27.3809523809524, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082401, Length=346, Percent_Identity=26.0115606936416, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082125, Length=336, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788075, Length=263, Percent_Identity=25.4752851711027, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787863, Length=333, Percent_Identity=23.7237237237237, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786518, Length=319, Percent_Identity=26.6457680250784, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786825, Length=396, Percent_Identity=24.4949494949495, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788407, Length=332, Percent_Identity=25.6024096385542, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI226510941, Length=122, Percent_Identity=33.6065573770492, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=351, Percent_Identity=26.4957264957265, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17562876, Length=335, Percent_Identity=26.865671641791, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562584, Length=315, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562878, Length=341, Percent_Identity=26.3929618768328, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=340, Percent_Identity=23.8235294117647, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=295, Percent_Identity=25.0847457627119, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=225, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=353, Percent_Identity=26.628895184136, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324486, Length=332, Percent_Identity=28.6144578313253, Blast_Score=108, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6323961, Length=332, Percent_Identity=27.4096385542169, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=332, Percent_Identity=26.5060240963855, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=25, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322619, Length=340, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=340, Percent_Identity=26.4705882352941, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323099, Length=341, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323980, Length=323, Percent_Identity=25.077399380805, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319258, Length=273, Percent_Identity=24.9084249084249, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221330659, Length=222, Percent_Identity=25.6756756756757, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920632, Length=222, Percent_Identity=25.6756756756757, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17137530, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581345, Length=222, Percent_Identity=23.8738738738739, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17737897, Length=220, Percent_Identity=29.0909090909091, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 37516; Mature: 37516

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVARIHQHGGPEVLVYEDVPEPKIKANQVLIRVRACALNHLDLFVRAGIPGMKFSMPHV
CCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
LGSDIAGEVVEVGELCERVKPGWRVLLAPGVSCRQCEQCLSGKDNFCRKFTNLGYGVDGG
HCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCC
NTELLAVSEYSVIQIPDDMSFEDAAAAPLVFLTAWHMLMSRARLQAGEDVLVLSASSGVG
CEEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
TAAIQIAKLFHCRVIATAGNEQKLAKARELGADHVIDHYQQDISAEVRKFTGKRGVDVVV
HHHHHHHHHHHHEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EHVGLATWQKSLESLALGGRLITCGATTGYDARVDLRFLFSKQWSLLGSFMGTLGELHQV
HHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LKFVFRKQLHPVIDRAFPLSGIAEAHRYLENKEQFGKVILTV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHCCEEEEC
>Mature Secondary Structure
MKVARIHQHGGPEVLVYEDVPEPKIKANQVLIRVRACALNHLDLFVRAGIPGMKFSMPHV
CCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
LGSDIAGEVVEVGELCERVKPGWRVLLAPGVSCRQCEQCLSGKDNFCRKFTNLGYGVDGG
HCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCC
NTELLAVSEYSVIQIPDDMSFEDAAAAPLVFLTAWHMLMSRARLQAGEDVLVLSASSGVG
CEEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
TAAIQIAKLFHCRVIATAGNEQKLAKARELGADHVIDHYQQDISAEVRKFTGKRGVDVVV
HHHHHHHHHHHHEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EHVGLATWQKSLESLALGGRLITCGATTGYDARVDLRFLFSKQWSLLGSFMGTLGELHQV
HHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LKFVFRKQLHPVIDRAFPLSGIAEAHRYLENKEQFGKVILTV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]