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The map label for this gene is yohM [C]

Identifier: 116621489

GI number: 116621489

Start: 3021676

End: 3023034

Strand: Reverse

Name: yohM [C]

Synonym: Acid_2371

Alternate gene names: 116621489

Gene position: 3023034-3021676 (Counterclockwise)

Preceding gene: 116621493

Following gene: 116621484

Centisome position: 30.33

GC content: 66.89

Gene sequence:

>1359_bases
ATGACGAAAAGACTCCCGCTGCTTGCGGCCCTTTGCGCCGCCCTCGCCGCCGGCCACCCGATGGGCAATTTCAGCGTCAA
CCACTACGCCCGCTTCGAGCCCTCCGCGCGCGGCCTGGCCATTCGTTATGTCATGGATCTCGCCGAGATCCCCACCTTCG
AGCTCTTCCAGCAGTGGGGCCCGGGCGCGGACCCGAAGGCGAAGGCCCTCGACCAGGCCCGCGAATGGGCCGCCCACCTG
GCGATCACGGTGGCCGGTAAGCCCGTCAAAGCGCGCGTCGAGCACGCCGCCATCGTGCTCGCCGAGGGCGCCGGCAACAT
GCAGGTCGCGCGCATCACCGCCGACCTGATCGTCGATGCCGCGGGCGGCCGCGTCGCCTTCGAAGATCGCAACTACGAAG
GCCGCAGCGGCTGGAAGGAAATCGTCCGCCCTGGCGCGGCGGATCGCAGCGCCGGGTTGACTGCCTATCCCAGCGACCCG
ATGCTTGCTCCGCCGCAGGACGTCAAGACATCCTTCTTATGGACGGTCGCTCCGGCCTCGCCGCGCGTGGAAACGCCGGT
CGCCGCTCCTCCGCCACCACCACCGCCCGGAACCGTGGTGAAGGGAGACTATCTTTCGACGCTGCTCCGCCGCAGCGAAA
TCGGCTGGCAGCTGACCCTGATCGGCATCGCGGTGGCGTTCGGGCTCGGCGCCATGCACGCGATGTCGCCGGGCCATGGA
AAGACCATCGTCGCGGCTTATCTGGTGGGTTCGCGCGGCACCTTCAAACACGCGATCTTCCTCGGCGGCATGGTGACGTT
CACCCACACCGCCAGCGTTTTCGCGCTGGGTTTCGTGACGCTCTTTCTCTCCCGCTACGTGCTGCCCGAAACGCTCTTCC
CGATCCTCGGCGCGATTTCCGGCCTGAGCATCGTGTGGGTCGGGGCCATGCTTTTCTTCCGCCGCCTGCACCGCCACGGA
CATGATCATCACCATCATCATGGGGATGGCCACACGCACTCGCACTCCCACGTTCCGGAAGGTGAGATCACCATGGGCAG
CCTGATCGCCCTCGGCGCCAGCGGAGGCCTCGTTCCCTGCCCTTCCGCGCTGGTGCTTCTGTTGAGCGCCATCTCGCTCG
GACGCGTCGGCCTGGGCATGCTTCTCTTGGTAGGCTTCAGCGCGGGCCTCGCAACGGTCCTCATGGGAATGGGCGTGCTG
GTTCTTTGCGTCGGGAATCTCCTTCCAGCGACGCAGAAGTTCACGGCGACCCGGGCCTTCCGACTGCTGCCCGCCGCCTC
CGCGGCCCTCATCACCTGCGTCGGCCTGGTGATGACGTGCGTTTCGCTCGGCATCATCCGGCCCTTCGCGATTGGATAG

Upstream 100 bases:

>100_bases
CTGGAATTGCGGAAGCGAAGTTACAAAAAAGAAGGCGACCAACAGATTTCGCAGCATCCGATACCATCCATTTTCGCACT
TCCGCTCGTATACCAGTCAA

Downstream 100 bases:

>100_bases
TCCGCAGGGCGCAGTTGTGCCATTAGTTGGGGGAATACTTGTTCGTTGCGGCGGCCGGGGACATACGGTCTTATCGCCGG
GTGGGGCCCGGCCGCCAGTG

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTKRLPLLAALCAALAAGHPMGNFSVNHYARFEPSARGLAIRYVMDLAEIPTFELFQQWGPGADPKAKALDQAREWAAHL
AITVAGKPVKARVEHAAIVLAEGAGNMQVARITADLIVDAAGGRVAFEDRNYEGRSGWKEIVRPGAADRSAGLTAYPSDP
MLAPPQDVKTSFLWTVAPASPRVETPVAAPPPPPPPGTVVKGDYLSTLLRRSEIGWQLTLIGIAVAFGLGAMHAMSPGHG
KTIVAAYLVGSRGTFKHAIFLGGMVTFTHTASVFALGFVTLFLSRYVLPETLFPILGAISGLSIVWVGAMLFFRRLHRHG
HDHHHHHGDGHTHSHSHVPEGEITMGSLIALGASGGLVPCPSALVLLLSAISLGRVGLGMLLLVGFSAGLATVLMGMGVL
VLCVGNLLPATQKFTATRAFRLLPAASAALITCVGLVMTCVSLGIIRPFAIG

Sequences:

>Translated_452_residues
MTKRLPLLAALCAALAAGHPMGNFSVNHYARFEPSARGLAIRYVMDLAEIPTFELFQQWGPGADPKAKALDQAREWAAHL
AITVAGKPVKARVEHAAIVLAEGAGNMQVARITADLIVDAAGGRVAFEDRNYEGRSGWKEIVRPGAADRSAGLTAYPSDP
MLAPPQDVKTSFLWTVAPASPRVETPVAAPPPPPPPGTVVKGDYLSTLLRRSEIGWQLTLIGIAVAFGLGAMHAMSPGHG
KTIVAAYLVGSRGTFKHAIFLGGMVTFTHTASVFALGFVTLFLSRYVLPETLFPILGAISGLSIVWVGAMLFFRRLHRHG
HDHHHHHGDGHTHSHSHVPEGEITMGSLIALGASGGLVPCPSALVLLLSAISLGRVGLGMLLLVGFSAGLATVLMGMGVL
VLCVGNLLPATQKFTATRAFRLLPAASAALITCVGLVMTCVSLGIIRPFAIG
>Mature_451_residues
TKRLPLLAALCAALAAGHPMGNFSVNHYARFEPSARGLAIRYVMDLAEIPTFELFQQWGPGADPKAKALDQAREWAAHLA
ITVAGKPVKARVEHAAIVLAEGAGNMQVARITADLIVDAAGGRVAFEDRNYEGRSGWKEIVRPGAADRSAGLTAYPSDPM
LAPPQDVKTSFLWTVAPASPRVETPVAAPPPPPPPGTVVKGDYLSTLLRRSEIGWQLTLIGIAVAFGLGAMHAMSPGHGK
TIVAAYLVGSRGTFKHAIFLGGMVTFTHTASVFALGFVTLFLSRYVLPETLFPILGAISGLSIVWVGAMLFFRRLHRHGH
DHHHHHGDGHTHSHSHVPEGEITMGSLIALGASGGLVPCPSALVLLLSAISLGRVGLGMLLLVGFSAGLATVLMGMGVLV
LCVGNLLPATQKFTATRAFRLLPAASAALITCVGLVMTCVSLGIIRPFAIG

Specific function: Efflux system for nickel and cobalt (Potential) [H]

COG id: COG2215

COG function: function code R; ABC-type uncharacterized transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

Organism=Escherichia coli, GI1788423, Length=247, Percent_Identity=29.5546558704453, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 47531; Mature: 47400

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRLPLLAALCAALAAGHPMGNFSVNHYARFEPSARGLAIRYVMDLAEIPTFELFQQWG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHC
PGADPKAKALDQAREWAAHLAITVAGKPVKARVEHAAIVLAEGAGNMQVARITADLIVDA
CCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHCEEEEEEEECCCCEEEEEEEEEHHEEC
AGGRVAFEDRNYEGRSGWKEIVRPGAADRSAGLTAYPSDPMLAPPQDVKTSFLWTVAPAS
CCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHHCCEEEEEECCCC
PRVETPVAAPPPPPPPGTVVKGDYLSTLLRRSEIGWQLTLIGIAVAFGLGAMHAMSPGHG
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHCCCCCC
KTIVAAYLVGSRGTFKHAIFLGGMVTFTHTASVFALGFVTLFLSRYVLPETLFPILGAIS
CEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSIVWVGAMLFFRRLHRHGHDHHHHHGDGHTHSHSHVPEGEITMGSLIALGASGGLVPC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCC
PSALVLLLSAISLGRVGLGMLLLVGFSAGLATVLMGMGVLVLCVGNLLPATQKFTATRAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RLLPAASAALITCVGLVMTCVSLGIIRPFAIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKRLPLLAALCAALAAGHPMGNFSVNHYARFEPSARGLAIRYVMDLAEIPTFELFQQWG
CCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHC
PGADPKAKALDQAREWAAHLAITVAGKPVKARVEHAAIVLAEGAGNMQVARITADLIVDA
CCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHCEEEEEEEECCCCEEEEEEEEEHHEEC
AGGRVAFEDRNYEGRSGWKEIVRPGAADRSAGLTAYPSDPMLAPPQDVKTSFLWTVAPAS
CCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCEECCCCCCCCCCHHHCCEEEEEECCCC
PRVETPVAAPPPPPPPGTVVKGDYLSTLLRRSEIGWQLTLIGIAVAFGLGAMHAMSPGHG
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHCCCCCC
KTIVAAYLVGSRGTFKHAIFLGGMVTFTHTASVFALGFVTLFLSRYVLPETLFPILGAIS
CEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSIVWVGAMLFFRRLHRHGHDHHHHHGDGHTHSHSHVPEGEITMGSLIALGASGGLVPC
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCC
PSALVLLLSAISLGRVGLGMLLLVGFSAGLATVLMGMGVLVLCVGNLLPATQKFTATRAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RLLPAASAALITCVGLVMTCVSLGIIRPFAIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]