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The map label for this gene is dapA [H]

Identifier: 116621377

GI number: 116621377

Start: 2885407

End: 2886420

Strand: Reverse

Name: dapA [H]

Synonym: Acid_2258

Alternate gene names: 116621377

Gene position: 2886420-2885407 (Counterclockwise)

Preceding gene: 116621382

Following gene: 116621376

Centisome position: 28.96

GC content: 64.99

Gene sequence:

>1014_bases
ATGCCAGCCAAACTGGAAGGTATCTTCACACCCACGCTCGTCCCGCTCGATGATCGCGGCGAAATCAACGAAGGGGAGCT
GCGCCGTTTTGTCTCCTGGCTGATCGAGCGCGGCGTACACGGGCTTTATCCGAATGGGTCCACCGGCGAGTTCACGCGCT
TCAGCGAAGCCGAGCGGCGGCGGATCGTGCAGATCACGTGCGACGAAGCGCGCGGACGCGTCCCGATCCTGGCCGGCGCG
GCCGAAGCCAATGTGAAAGAGACCCTCGCGGCCTGCGAGGCTTACGCGGGGATGGGCGCGCGCGCGGTGGCGATTGTCTC
GCCGTTTTACTTCCGCCTCTCGCCGGAATCGGTCTACGCTTACTTCGCAGAAATCGCCAGCCATACGCCGATCGACGTCA
CGCTGTACAACATCCCGATGTTCGCGAGCCCCATAGACGTACCGACCATCCGGCGCCTGGCCGAGTTCCCGCGCATCGTC
GGCATCAAGGATTCCTCGGGCGACCTGGCCTTCATGATGCGCCTGATCGCAGCGGTGCGCCCCTCGCGCCCCGACTTCAC
CTTCCTCACCGGCTGGGAAGCAGTGCTGGCGCCGATGATCCTGGTCGGCTGCGATGGCGGCACCAACGCCAGCAGCAACG
CTGTGCCCGAAGTCACGCGCCGCATCTACGAACTTGCGAAGGCGGGGAAATACGAAGAGGCGATGAAGTGGCAGTACCGC
ATCACGGAACTCTTCGATGCCATGCTGTTCCCCTTTGAGTTTCCGGATGGCTTCCGCGCCGCCGCCGAATTCCGCGGCTT
CCGTTTCGGCCGCGGCCGCCTGCCGCAGACCACGGCGCAGCGCACCGACCGCGAAGCGCTCGCCAAAGTGCTGCAATGCA
TCCTGGCCGATTTCGAACTGGTGAATCCGCCGGCCGCCGGCTGCGCTCCCCGGACCGCCCAACCCGCTGCGGACAAGATG
GAGCAGGTGGTGCTCGAGGTGCTCCATGAGCTCGAGAAGCGGGGGATCTTTTGA

Upstream 100 bases:

>100_bases
GGACATGCCGCGAGTACCTCCCAAAGAGTTCCCGCTCATAATAACAACTCTCGCCGTGGCCCTTCGGTACCGTGAGTTAA
ACTCTTAAGGACGCCTGCAC

Downstream 100 bases:

>100_bases
ACGAAGGCGCGCTCGCCTTGGTCGAAATCGGCGGCTGGTCGCCCGGCATGGTGCTGCTGGACGCCATGGAGAAGGCCGCC
GGCGTCAGCATTTTGCAGAC

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MPAKLEGIFTPTLVPLDDRGEINEGELRRFVSWLIERGVHGLYPNGSTGEFTRFSEAERRRIVQITCDEARGRVPILAGA
AEANVKETLAACEAYAGMGARAVAIVSPFYFRLSPESVYAYFAEIASHTPIDVTLYNIPMFASPIDVPTIRRLAEFPRIV
GIKDSSGDLAFMMRLIAAVRPSRPDFTFLTGWEAVLAPMILVGCDGGTNASSNAVPEVTRRIYELAKAGKYEEAMKWQYR
ITELFDAMLFPFEFPDGFRAAAEFRGFRFGRGRLPQTTAQRTDREALAKVLQCILADFELVNPPAAGCAPRTAQPAADKM
EQVVLEVLHELEKRGIF

Sequences:

>Translated_337_residues
MPAKLEGIFTPTLVPLDDRGEINEGELRRFVSWLIERGVHGLYPNGSTGEFTRFSEAERRRIVQITCDEARGRVPILAGA
AEANVKETLAACEAYAGMGARAVAIVSPFYFRLSPESVYAYFAEIASHTPIDVTLYNIPMFASPIDVPTIRRLAEFPRIV
GIKDSSGDLAFMMRLIAAVRPSRPDFTFLTGWEAVLAPMILVGCDGGTNASSNAVPEVTRRIYELAKAGKYEEAMKWQYR
ITELFDAMLFPFEFPDGFRAAAEFRGFRFGRGRLPQTTAQRTDREALAKVLQCILADFELVNPPAAGCAPRTAQPAADKM
EQVVLEVLHELEKRGIF
>Mature_336_residues
PAKLEGIFTPTLVPLDDRGEINEGELRRFVSWLIERGVHGLYPNGSTGEFTRFSEAERRRIVQITCDEARGRVPILAGAA
EANVKETLAACEAYAGMGARAVAIVSPFYFRLSPESVYAYFAEIASHTPIDVTLYNIPMFASPIDVPTIRRLAEFPRIVG
IKDSSGDLAFMMRLIAAVRPSRPDFTFLTGWEAVLAPMILVGCDGGTNASSNAVPEVTRRIYELAKAGKYEEAMKWQYRI
TELFDAMLFPFEFPDGFRAAAEFRGFRFGRGRLPQTTAQRTDREALAKVLQCILADFELVNPPAAGCAPRTAQPAADKME
QVVLEVLHELEKRGIF

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=287, Percent_Identity=27.5261324041812, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI13540533, Length=249, Percent_Identity=24.0963855421687, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI87082415, Length=243, Percent_Identity=28.8065843621399, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786463, Length=244, Percent_Identity=28.2786885245902, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789620, Length=251, Percent_Identity=29.0836653386454, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788823, Length=288, Percent_Identity=26.3888888888889, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 37392; Mature: 37261

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKLEGIFTPTLVPLDDRGEINEGELRRFVSWLIERGVHGLYPNGSTGEFTRFSEAERR
CCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCC
RIVQITCDEARGRVPILAGAAEANVKETLAACEAYAGMGARAVAIVSPFYFRLSPESVYA
EEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHEECCHHEEECHHHHHH
YFAEIASHTPIDVTLYNIPMFASPIDVPTIRRLAEFPRIVGIKDSSGDLAFMMRLIAAVR
HHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHC
PSRPDFTFLTGWEAVLAPMILVGCDGGTNASSNAVPEVTRRIYELAKAGKYEEAMKWQYR
CCCCCEEEECCHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
ITELFDAMLFPFEFPDGFRAAAEFRGFRFGRGRLPQTTAQRTDREALAKVLQCILADFEL
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
VNPPAAGCAPRTAQPAADKMEQVVLEVLHELEKRGIF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PAKLEGIFTPTLVPLDDRGEINEGELRRFVSWLIERGVHGLYPNGSTGEFTRFSEAERR
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCC
RIVQITCDEARGRVPILAGAAEANVKETLAACEAYAGMGARAVAIVSPFYFRLSPESVYA
EEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHEECCHHEEECHHHHHH
YFAEIASHTPIDVTLYNIPMFASPIDVPTIRRLAEFPRIVGIKDSSGDLAFMMRLIAAVR
HHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHC
PSRPDFTFLTGWEAVLAPMILVGCDGGTNASSNAVPEVTRRIYELAKAGKYEEAMKWQYR
CCCCCEEEECCHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
ITELFDAMLFPFEFPDGFRAAAEFRGFRFGRGRLPQTTAQRTDREALAKVLQCILADFEL
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
VNPPAAGCAPRTAQPAADKMEQVVLEVLHELEKRGIF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]