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The map label for this gene is pqqL [C]

Identifier: 116621267

GI number: 116621267

Start: 2748442

End: 2749749

Strand: Direct

Name: pqqL [C]

Synonym: Acid_2148

Alternate gene names: 116621267

Gene position: 2748442-2749749 (Clockwise)

Preceding gene: 116621263

Following gene: 116621268

Centisome position: 27.58

GC content: 57.8

Gene sequence:

>1308_bases
ATGCGGTTCTTCATCAGTCTGCTGATTTTCACGATGCTCGCGGGTGCGCAAAGCCTCGACGTTCAGACCACCACTCTCGA
CAATGGAATGAAAATTCTGGTCCAGCAGGATCGGAATATTCCCAATGTCGCCATGTATTTCTTTTATCGCATAGGCTCGC
GCAACGAAGCCCCGGGAACCACGGGAATCTCGCACTTCTTCGAACACATGATGTTCAACGGCGCGAAAAAATACGGCCCC
AAGCAGTTCGACAACGAAATGGAGAAGGCCGGCGGCAATAACAACGCGTCCACCGGCCAGGACCTGACGATCTACACCGA
CTGGTTCCCGAGCAGCGCGCTGGAGTTGATGATGGATATGGAGGGCGACCGCATCCGCGACCTGGCCTTCGATCCCAAGA
TAGTTCAGTCGGAACGCGGCGTGGTTTATTCCGAGCGGCGCACTTCGGTAGACAACAACAATTTCGGAATTCTCCACGAA
CAATTGCAGGCGGCTGCGTTTACCGCCCATCCCTATCACTGGCCCGTGGTCGGCTGGCCCTCCGACATCGAAGCCTGGAC
CATGCAGGACCTGAAGAATTATTTCGCCATCGGCTACGCGCCGAATAACTGCACCATGGTAGTGGTCGGCGATGTAACCG
CGGAGCGCGTGATCGCGCTCGCGAAAAAGTACATCGAGCCGATTCCCCGCCACGAACCCCCGCCGCCCGTCCGCACCAAA
GAGCCGGAGCAGCTTGGCGAACGCCGCGTGATCGTCAGGAAGCCCGCCCAGCTACCGCTCCAAATGATCGCCTTCCATGT
GCCCGAAGCCAGGAATCCCGATGCCAAGGTCCTGGATCTGATCGCTACCGTTCTCTCCACGGGCCAGAGTTCACGCCTGT
ACAAACGGATGGTGGACGAAGAGGCGCTGGCTCTCTCCGTGAATGGACGCGCCGGCGATTCATTCGATCCAACCCTGATG
ATCTTCACGATTCAGCCGCGCAGCGGTGTGGATCTGGCCAGAACCGAAAAGGCCTTGTACGACGAACTGGAGCGTCTGCA
AACAGCGGAGGTTCCCGCCAGGGAGTTGCAGAAAGCCAAAAACCAGATGCTCGCCGCCCAGTACCGGCAGATGAAGACCA
TCGCCGGGCGAGCCTCGATGTTGGGTCACTATGAGGTTGTTCTAGGGGACTACCGGAAGCTGTTTACGCTGGATAAGGAT
CTGGAAGCCGTGACGGCGGGCGACGTCCAGCGCGTTGCCAGGAAATACTTCCTCGAGAAGAATCGCACGGTTGCTACGTT
GATTCCCGAATCCAAGGAGGGCAAATAG

Upstream 100 bases:

>100_bases
TACTCATCCGGTCATCCATATAGTCTTTACGCACCTCAACGCGTTTAGGATACGGGGAGCAGCGTGCGTTCCAACTCGTA
TTCTGGTAGGTTTGTTTCCG

Downstream 100 bases:

>100_bases
GCAATGAAACCGCTCCTATTATTGGCCTTTGCTATGTCGCTCGCCTTCGGCCAGGCCAAGCTTCCTCCGTACACGCGCGA
GACGCTGCCCAACGGCGCGG

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MRFFISLLIFTMLAGAQSLDVQTTTLDNGMKILVQQDRNIPNVAMYFFYRIGSRNEAPGTTGISHFFEHMMFNGAKKYGP
KQFDNEMEKAGGNNNASTGQDLTIYTDWFPSSALELMMDMEGDRIRDLAFDPKIVQSERGVVYSERRTSVDNNNFGILHE
QLQAAAFTAHPYHWPVVGWPSDIEAWTMQDLKNYFAIGYAPNNCTMVVVGDVTAERVIALAKKYIEPIPRHEPPPPVRTK
EPEQLGERRVIVRKPAQLPLQMIAFHVPEARNPDAKVLDLIATVLSTGQSSRLYKRMVDEEALALSVNGRAGDSFDPTLM
IFTIQPRSGVDLARTEKALYDELERLQTAEVPARELQKAKNQMLAAQYRQMKTIAGRASMLGHYEVVLGDYRKLFTLDKD
LEAVTAGDVQRVARKYFLEKNRTVATLIPESKEGK

Sequences:

>Translated_435_residues
MRFFISLLIFTMLAGAQSLDVQTTTLDNGMKILVQQDRNIPNVAMYFFYRIGSRNEAPGTTGISHFFEHMMFNGAKKYGP
KQFDNEMEKAGGNNNASTGQDLTIYTDWFPSSALELMMDMEGDRIRDLAFDPKIVQSERGVVYSERRTSVDNNNFGILHE
QLQAAAFTAHPYHWPVVGWPSDIEAWTMQDLKNYFAIGYAPNNCTMVVVGDVTAERVIALAKKYIEPIPRHEPPPPVRTK
EPEQLGERRVIVRKPAQLPLQMIAFHVPEARNPDAKVLDLIATVLSTGQSSRLYKRMVDEEALALSVNGRAGDSFDPTLM
IFTIQPRSGVDLARTEKALYDELERLQTAEVPARELQKAKNQMLAAQYRQMKTIAGRASMLGHYEVVLGDYRKLFTLDKD
LEAVTAGDVQRVARKYFLEKNRTVATLIPESKEGK
>Mature_435_residues
MRFFISLLIFTMLAGAQSLDVQTTTLDNGMKILVQQDRNIPNVAMYFFYRIGSRNEAPGTTGISHFFEHMMFNGAKKYGP
KQFDNEMEKAGGNNNASTGQDLTIYTDWFPSSALELMMDMEGDRIRDLAFDPKIVQSERGVVYSERRTSVDNNNFGILHE
QLQAAAFTAHPYHWPVVGWPSDIEAWTMQDLKNYFAIGYAPNNCTMVVVGDVTAERVIALAKKYIEPIPRHEPPPPVRTK
EPEQLGERRVIVRKPAQLPLQMIAFHVPEARNPDAKVLDLIATVLSTGQSSRLYKRMVDEEALALSVNGRAGDSFDPTLM
IFTIQPRSGVDLARTEKALYDELERLQTAEVPARELQKAKNQMLAAQYRQMKTIAGRASMLGHYEVVLGDYRKLFTLDKD
LEAVTAGDVQRVARKYFLEKNRTVATLIPESKEGK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=419, Percent_Identity=21.2410501193317, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI46593007, Length=268, Percent_Identity=24.2537313432836, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1787770, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=230, Percent_Identity=25.2173913043478, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17553678, Length=418, Percent_Identity=22.2488038277512, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323192, Length=363, Percent_Identity=24.5179063360882, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357875, Length=423, Percent_Identity=23.4042553191489, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24646943, Length=423, Percent_Identity=23.4042553191489, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49118; Mature: 49118

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFISLLIFTMLAGAQSLDVQTTTLDNGMKILVQQDRNIPNVAMYFFYRIGSRNEAPGT
CHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
TGISHFFEHMMFNGAKKYGPKQFDNEMEKAGGNNNASTGQDLTIYTDWFPSSALELMMDM
CHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHC
EGDRIRDLAFDPKIVQSERGVVYSERRTSVDNNNFGILHEQLQAAAFTAHPYHWPVVGWP
CCCHHHHCCCCCHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCC
SDIEAWTMQDLKNYFAIGYAPNNCTMVVVGDVTAERVIALAKKYIEPIPRHEPPPPVRTK
CCCHHHHHHHHHHHEEEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EPEQLGERRVIVRKPAQLPLQMIAFHVPEARNPDAKVLDLIATVLSTGQSSRLYKRMVDE
CHHHHCCCEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
EALALSVNGRAGDSFDPTLMIFTIQPRSGVDLARTEKALYDELERLQTAEVPARELQKAK
CEEEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NQMLAAQYRQMKTIAGRASMLGHYEVVLGDYRKLFTLDKDLEAVTAGDVQRVARKYFLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
NRTVATLIPESKEGK
CCEEEEECCCCCCCC
>Mature Secondary Structure
MRFFISLLIFTMLAGAQSLDVQTTTLDNGMKILVQQDRNIPNVAMYFFYRIGSRNEAPGT
CHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
TGISHFFEHMMFNGAKKYGPKQFDNEMEKAGGNNNASTGQDLTIYTDWFPSSALELMMDM
CHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHC
EGDRIRDLAFDPKIVQSERGVVYSERRTSVDNNNFGILHEQLQAAAFTAHPYHWPVVGWP
CCCHHHHCCCCCHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCC
SDIEAWTMQDLKNYFAIGYAPNNCTMVVVGDVTAERVIALAKKYIEPIPRHEPPPPVRTK
CCCHHHHHHHHHHHEEEEEECCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
EPEQLGERRVIVRKPAQLPLQMIAFHVPEARNPDAKVLDLIATVLSTGQSSRLYKRMVDE
CHHHHCCCEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
EALALSVNGRAGDSFDPTLMIFTIQPRSGVDLARTEKALYDELERLQTAEVPARELQKAK
CEEEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NQMLAAQYRQMKTIAGRASMLGHYEVVLGDYRKLFTLDKDLEAVTAGDVQRVARKYFLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
NRTVATLIPESKEGK
CCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]