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The map label for this gene is soxB [H]

Identifier: 116620986

GI number: 116620986

Start: 2324316

End: 2325473

Strand: Reverse

Name: soxB [H]

Synonym: Acid_1867

Alternate gene names: 116620986

Gene position: 2325473-2324316 (Counterclockwise)

Preceding gene: 116620987

Following gene: 116620985

Centisome position: 23.33

GC content: 64.85

Gene sequence:

>1158_bases
TTGAGGTCGGCGGACGTCATTATCATTGGGGCCGGGATTGTCGGTTCGAGCATTGCGTATCACCTGACCGAGGCGGGGTG
CACTAACGTTCTTGTTCTCGAACGCGAAACCAGCCAAGGCAAGGGATCCACGGGCAAGAGCATGGGCGGCGTGCGCGCGC
AGTTCGCCACGCCCGTCAACATCCGCATGTCCATGTACTCCATCCCTTTCTTCGCAGCCTTCGATGAAGTCATGGGCCAC
CCCGCGGGTTACCGTCCGCAAGGGTATCTCTTCGTCGCCACCAAGCCGGCGCACATGGATTATCTCCGCGAAAACTACCG
CGCCCAAGTCGAAGCCGGGCTCAAGGACGTCCACCTGCTCGACCCCGCCGGCGTCTCCCGGCTCGCCCCCGAACTGCGGA
GCGACGATATCATCGGCGGCAGTTTCTGCGCGACCGACGGCTTCGTGGATCCGCACAGCGTGATGACCGGCTTCATGCTC
AAAGCCATGGAGCGCGGCGTCGAGCTGCTGCGCGACACCGAAGTCACCGGCATTCGCACCGACGCCGCCGGTGTCTGCGG
CGTCGAAACCTCCGCGGGATTCCTCTCCAGCCGGACAGTAGTCAACGCCACTGGCGCATGGGCCGGCAGCGTCGCCCGAC
TGGCCGGCGTGGACCTTCCGGTAGAACCCCTGCGCCGCATGCTGGTGCCCACCGAGCCCTTCGACAAGGTCTCGCACGAA
TCGCCCATGGTGGTCGATATGAACACCGGCTTCCACTACCGCCCCGAGGGCCGCGGGCTTCTGCTCGCCTGGAACGACCC
GGAAGAAACCCCCGGCTTCAAGCTCAACTTCGACCGCGCGTTCATCGAAAAAGTGCTGACCCGCGGCGTGGACCGCTTGC
CCTGCCTGGAAGAGGCCGAGGTCAACCCCAAGCGCGCCTGGGCCGGCCTCTATGAAATGACACCCGACCACCACCCGGTG
ATCGGCCCGGTCAAATCACTGCCTGGCTTTTTTCTGGCCAACGGCTTCAGCGGTCACGGCGTCATGCACTCGCCTGCCAC
CGGACGCATCCTCGCGGACCTGATCGTTCACGGCCGCTGCGACCTGGTGGACACGGACCTCCTCGGCTTCGATCGCTTCG
CCGCCGGCCGCCTGCTCCATGAGACCGCAGTACTTTAG

Upstream 100 bases:

>100_bases
CCCTCTCGCCGGCAACGCCGACGCCGAAGAAGCCAAATCCCAGCGGTAACAATGCCGTGTCGTTTTAGTAGAATGTGTAA
GCGCTTTCCAGGAGGCATAT

Downstream 100 bases:

>100_bases
GAAGGAGTTTCGCATGCTGTATACAAGACGGGATCTCGGAAAGCTCGCCGTGGCCGCCGGGACCGCGGGCAGGCTGCTGG
CGTCGAAGCCGAGTTCGAAT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MRSADVIIIGAGIVGSSIAYHLTEAGCTNVLVLERETSQGKGSTGKSMGGVRAQFATPVNIRMSMYSIPFFAAFDEVMGH
PAGYRPQGYLFVATKPAHMDYLRENYRAQVEAGLKDVHLLDPAGVSRLAPELRSDDIIGGSFCATDGFVDPHSVMTGFML
KAMERGVELLRDTEVTGIRTDAAGVCGVETSAGFLSSRTVVNATGAWAGSVARLAGVDLPVEPLRRMLVPTEPFDKVSHE
SPMVVDMNTGFHYRPEGRGLLLAWNDPEETPGFKLNFDRAFIEKVLTRGVDRLPCLEEAEVNPKRAWAGLYEMTPDHHPV
IGPVKSLPGFFLANGFSGHGVMHSPATGRILADLIVHGRCDLVDTDLLGFDRFAAGRLLHETAVL

Sequences:

>Translated_385_residues
MRSADVIIIGAGIVGSSIAYHLTEAGCTNVLVLERETSQGKGSTGKSMGGVRAQFATPVNIRMSMYSIPFFAAFDEVMGH
PAGYRPQGYLFVATKPAHMDYLRENYRAQVEAGLKDVHLLDPAGVSRLAPELRSDDIIGGSFCATDGFVDPHSVMTGFML
KAMERGVELLRDTEVTGIRTDAAGVCGVETSAGFLSSRTVVNATGAWAGSVARLAGVDLPVEPLRRMLVPTEPFDKVSHE
SPMVVDMNTGFHYRPEGRGLLLAWNDPEETPGFKLNFDRAFIEKVLTRGVDRLPCLEEAEVNPKRAWAGLYEMTPDHHPV
IGPVKSLPGFFLANGFSGHGVMHSPATGRILADLIVHGRCDLVDTDLLGFDRFAAGRLLHETAVL
>Mature_385_residues
MRSADVIIIGAGIVGSSIAYHLTEAGCTNVLVLERETSQGKGSTGKSMGGVRAQFATPVNIRMSMYSIPFFAAFDEVMGH
PAGYRPQGYLFVATKPAHMDYLRENYRAQVEAGLKDVHLLDPAGVSRLAPELRSDDIIGGSFCATDGFVDPHSVMTGFML
KAMERGVELLRDTEVTGIRTDAAGVCGVETSAGFLSSRTVVNATGAWAGSVARLAGVDLPVEPLRRMLVPTEPFDKVSHE
SPMVVDMNTGFHYRPEGRGLLLAWNDPEETPGFKLNFDRAFIEKVLTRGVDRLPCLEEAEVNPKRAWAGLYEMTPDHHPV
IGPVKSLPGFFLANGFSGHGVMHSPATGRILADLIVHGRCDLVDTDLLGFDRFAAGRLLHETAVL

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=384, Percent_Identity=29.6875, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI21361378, Length=384, Percent_Identity=29.6875, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24797151, Length=386, Percent_Identity=27.979274611399, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI8923708, Length=416, Percent_Identity=29.5673076923077, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI194306651, Length=397, Percent_Identity=24.6851385390428, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1787559, Length=388, Percent_Identity=23.9690721649485, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71994045, Length=400, Percent_Identity=25.25, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17541536, Length=429, Percent_Identity=27.5058275058275, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71994052, Length=407, Percent_Identity=24.8157248157248, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32563613, Length=406, Percent_Identity=26.8472906403941, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129729, Length=416, Percent_Identity=32.9326923076923, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571104, Length=384, Percent_Identity=27.34375, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20130091, Length=384, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17985989, Length=416, Percent_Identity=27.8846153846154, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41625; Mature: 41625

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSADVIIIGAGIVGSSIAYHLTEAGCTNVLVLERETSQGKGSTGKSMGGVRAQFATPVN
CCCCCEEEEECCHHHCHHHEEEHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCEE
IRMSMYSIPFFAAFDEVMGHPAGYRPQGYLFVATKPAHMDYLRENYRAQVEAGLKDVHLL
EEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEE
DPAGVSRLAPELRSDDIIGGSFCATDGFVDPHSVMTGFMLKAMERGVELLRDTEVTGIRT
CCCCHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
DAAGVCGVETSAGFLSSRTVVNATGAWAGSVARLAGVDLPVEPLRRMLVPTEPFDKVSHE
CCCCCCCCCCCCCHHCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHCCC
SPMVVDMNTGFHYRPEGRGLLLAWNDPEETPGFKLNFDRAFIEKVLTRGVDRLPCLEEAE
CCEEEEECCCEEECCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCC
VNPKRAWAGLYEMTPDHHPVIGPVKSLPGFFLANGFSGHGVMHSPATGRILADLIVHGRC
CCHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEECCCCCCCEEECCCCHHHHHHHHHCCCC
DLVDTDLLGFDRFAAGRLLHETAVL
CEECCCHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSADVIIIGAGIVGSSIAYHLTEAGCTNVLVLERETSQGKGSTGKSMGGVRAQFATPVN
CCCCCEEEEECCHHHCHHHEEEHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCEE
IRMSMYSIPFFAAFDEVMGHPAGYRPQGYLFVATKPAHMDYLRENYRAQVEAGLKDVHLL
EEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEE
DPAGVSRLAPELRSDDIIGGSFCATDGFVDPHSVMTGFMLKAMERGVELLRDTEVTGIRT
CCCCHHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
DAAGVCGVETSAGFLSSRTVVNATGAWAGSVARLAGVDLPVEPLRRMLVPTEPFDKVSHE
CCCCCCCCCCCCCHHCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHCCC
SPMVVDMNTGFHYRPEGRGLLLAWNDPEETPGFKLNFDRAFIEKVLTRGVDRLPCLEEAE
CCEEEEECCCEEECCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCC
VNPKRAWAGLYEMTPDHHPVIGPVKSLPGFFLANGFSGHGVMHSPATGRILADLIVHGRC
CCHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEECCCCCCCEEECCCCHHHHHHHHHCCCC
DLVDTDLLGFDRFAAGRLLHETAVL
CEECCCHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]