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The map label for this gene is aspC [H]

Identifier: 116620955

GI number: 116620955

Start: 2289345

End: 2290478

Strand: Reverse

Name: aspC [H]

Synonym: Acid_1836

Alternate gene names: 116620955

Gene position: 2290478-2289345 (Counterclockwise)

Preceding gene: 116620956

Following gene: 116620954

Centisome position: 22.98

GC content: 63.32

Gene sequence:

>1134_bases
GTGAAAATAGAACCATTCGAAATGGAGCGCATGCAATCGACCTGGGAGAACCTTGTCGAGTTCGACATGAGCGAGAGCGG
CGTGCGCCCGGTGAGTTTGCGCGAACTGGCGGAGATGGGGCTCGATCTGGATTCAATCCTCGATATGCCTCTCGGCTATA
GCCAGAGCAACGGCACTCTCGGGTTGCGCGAAGAGCTGACGCGCGTTTATCCCGGAGCGTCCGTGGACCAGATCGAAGTC
ACCAACGGGACCTCGGAAGCCAATTACCTGCTTGCGCTGGCGCTGCTTCGCGAGGGCGACGAGGTGGCGCTCGAAGTGCC
GAACTACATGCAGTATGGCGGAGTGCCTCGCAGCATGGGGGCGAAGATGAATCATTTCCGCCTGCGCATCGACGCCGATT
GGGAGCCGGATTGGGAGGAGTTCGAACGCGCGGTCAATCCGCGCACGCGCCTGGTCTATCTTTCGAACCCCAACAATCCG
AGCGGCAGTGTGCTGACGCCGGCGGCGATGGAGCGCATCGTGCGCCGCTGCGAGCAGGTAGGCGCGTATCTGCTGGCCGA
CGAAGTTTACCTCGGCGCCGAGATCCATCGCGAGCGGACGGCCAGCTTCTGGGGCATGAGCGATCGCGTGATCGTCACCA
GCGGGCTCTCCAAGGCGTATGGCATTCCCGGCGTGCGGATCGGCTGGATCGTGGGGCCGAAGGACGTGGTGGCGGAGTGC
TGGAGCCAGCACGATTACATTACGATCGGGCCGAACAAGATCTCCGACGCGGTGGCGCGGGTTGCCGTCCGCCCCGAAAA
TCGCGAGAAGCTTTACGCGCGCACACGCACAATTCTGCAGCAGAATCTGCCCGCGATGCGGCAGTGGGCGGAAAGCTTCG
ATGGCTTCCTCACCTTCCGGGAACCGCAGGCGGGCGCGCTTTGCCTGATGCGCTACGGGTCGCCGACGCCGAGCTATCAA
CTGGTGGAACGGATTCGGGTAAAGCAGAGCGTGCTGATTGTGCCCGGCTCTCACCTCGGCCTCGAAGGCTATCTGCGCGT
GTGGCTGGGCGGCAAGCCGGAGTTTCTCGCCGAGGGATTGCGGCGCATCGGCGTTGAGCTGCGTGCGGAGATCGGCCGCG
GAGCTCATGGCTGA

Upstream 100 bases:

>100_bases
CGCCCACGCTGGAGGACTCGGCCGGCATCACGGTCTGCGATTTCACCGGGCTGGGCGTGGAAGACTTGTATATCGCCGAA
TACTGCTACGAGAGGGCACA

Downstream 100 bases:

>100_bases
TACCGGCCCGGAGCTGAAGCGCGAACTCGGCCTGCGCGACGTCACGTTGTTCGCGATCGCGTGCATCGTGGGTACGCGCT
GGATCCCGGCGGCGGCGCAC

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKIEPFEMERMQSTWENLVEFDMSESGVRPVSLRELAEMGLDLDSILDMPLGYSQSNGTLGLREELTRVYPGASVDQIEV
TNGTSEANYLLALALLREGDEVALEVPNYMQYGGVPRSMGAKMNHFRLRIDADWEPDWEEFERAVNPRTRLVYLSNPNNP
SGSVLTPAAMERIVRRCEQVGAYLLADEVYLGAEIHRERTASFWGMSDRVIVTSGLSKAYGIPGVRIGWIVGPKDVVAEC
WSQHDYITIGPNKISDAVARVAVRPENREKLYARTRTILQQNLPAMRQWAESFDGFLTFREPQAGALCLMRYGSPTPSYQ
LVERIRVKQSVLIVPGSHLGLEGYLRVWLGGKPEFLAEGLRRIGVELRAEIGRGAHG

Sequences:

>Translated_377_residues
MKIEPFEMERMQSTWENLVEFDMSESGVRPVSLRELAEMGLDLDSILDMPLGYSQSNGTLGLREELTRVYPGASVDQIEV
TNGTSEANYLLALALLREGDEVALEVPNYMQYGGVPRSMGAKMNHFRLRIDADWEPDWEEFERAVNPRTRLVYLSNPNNP
SGSVLTPAAMERIVRRCEQVGAYLLADEVYLGAEIHRERTASFWGMSDRVIVTSGLSKAYGIPGVRIGWIVGPKDVVAEC
WSQHDYITIGPNKISDAVARVAVRPENREKLYARTRTILQQNLPAMRQWAESFDGFLTFREPQAGALCLMRYGSPTPSYQ
LVERIRVKQSVLIVPGSHLGLEGYLRVWLGGKPEFLAEGLRRIGVELRAEIGRGAHG
>Mature_377_residues
MKIEPFEMERMQSTWENLVEFDMSESGVRPVSLRELAEMGLDLDSILDMPLGYSQSNGTLGLREELTRVYPGASVDQIEV
TNGTSEANYLLALALLREGDEVALEVPNYMQYGGVPRSMGAKMNHFRLRIDADWEPDWEEFERAVNPRTRLVYLSNPNNP
SGSVLTPAAMERIVRRCEQVGAYLLADEVYLGAEIHRERTASFWGMSDRVIVTSGLSKAYGIPGVRIGWIVGPKDVVAEC
WSQHDYITIGPNKISDAVARVAVRPENREKLYARTRTILQQNLPAMRQWAESFDGFLTFREPQAGALCLMRYGSPTPSYQ
LVERIRVKQSVLIVPGSHLGLEGYLRVWLGGKPEFLAEGLRRIGVELRAEIGRGAHG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=340, Percent_Identity=24.4117647058824, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI56713254, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI56713256, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI95147551, Length=223, Percent_Identity=26.9058295964126, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI169881279, Length=223, Percent_Identity=26.9058295964126, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788627, Length=203, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790797, Length=301, Percent_Identity=26.578073089701, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788722, Length=289, Percent_Identity=26.9896193771626, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787710, Length=211, Percent_Identity=27.9620853080569, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=228, Percent_Identity=28.0701754385965, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=333, Percent_Identity=23.1231231231231, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=177, Percent_Identity=29.3785310734463, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994476, Length=177, Percent_Identity=29.3785310734463, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=207, Percent_Identity=27.536231884058, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573069, Length=299, Percent_Identity=27.4247491638796, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646114, Length=299, Percent_Identity=27.4247491638796, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573067, Length=299, Percent_Identity=27.4247491638796, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573065, Length=299, Percent_Identity=27.4247491638796, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859735, Length=348, Percent_Identity=23.5632183908046, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42319; Mature: 42319

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEPFEMERMQSTWENLVEFDMSESGVRPVSLRELAEMGLDLDSILDMPLGYSQSNGTL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
GLREELTRVYPGASVDQIEVTNGTSEANYLLALALLREGDEVALEVPNYMQYGGVPRSMG
CHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHC
AKMNHFRLRIDADWEPDWEEFERAVNPRTRLVYLSNPNNPSGSVLTPAAMERIVRRCEQV
CCCCEEEEEEECCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCEECHHHHHHHHHHHHHH
GAYLLADEVYLGAEIHRERTASFWGMSDRVIVTSGLSKAYGIPGVRIGWIVGPKDVVAEC
CHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCHHHCCCCCCEEEEEECCHHHHHHH
WSQHDYITIGPNKISDAVARVAVRPENREKLYARTRTILQQNLPAMRQWAESFDGFLTFR
HCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEE
EPQAGALCLMRYGSPTPSYQLVERIRVKQSVLIVPGSHLGLEGYLRVWLGGKPEFLAEGL
CCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCEEEEEEECCCHHHHHHHH
RRIGVELRAEIGRGAHG
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIEPFEMERMQSTWENLVEFDMSESGVRPVSLRELAEMGLDLDSILDMPLGYSQSNGTL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCC
GLREELTRVYPGASVDQIEVTNGTSEANYLLALALLREGDEVALEVPNYMQYGGVPRSMG
CHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHC
AKMNHFRLRIDADWEPDWEEFERAVNPRTRLVYLSNPNNPSGSVLTPAAMERIVRRCEQV
CCCCEEEEEEECCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCEECHHHHHHHHHHHHHH
GAYLLADEVYLGAEIHRERTASFWGMSDRVIVTSGLSKAYGIPGVRIGWIVGPKDVVAEC
CHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCHHHCCCCCCEEEEEECCHHHHHHH
WSQHDYITIGPNKISDAVARVAVRPENREKLYARTRTILQQNLPAMRQWAESFDGFLTFR
HCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEE
EPQAGALCLMRYGSPTPSYQLVERIRVKQSVLIVPGSHLGLEGYLRVWLGGKPEFLAEGL
CCCCCEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCCCCCCEEEEEEECCCHHHHHHHH
RRIGVELRAEIGRGAHG
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]