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The map label for this gene is macB [H]

Identifier: 116620887

GI number: 116620887

Start: 2196192

End: 2196716

Strand: Direct

Name: macB [H]

Synonym: Acid_1768

Alternate gene names: 116620887

Gene position: 2196192-2196716 (Clockwise)

Preceding gene: 116620885

Following gene: 116620888

Centisome position: 22.04

GC content: 67.24

Gene sequence:

>525_bases
GTGATCCGCACGCGCACGGACGCGGGGGCGATGGTGGAGACGCTCGGCGCCACCATCCGCGGTGTGGACCCGGAAATCCC
CACATACGACATGTTTGCGATGGAGGCGTTGGTGGAGCGCTCCACGGTGCAGCGGCGATTTGTGATGATGCTGCTCACCG
GGTTCGCACTGGCGGCGCTGCTGCTGGCGGGAGTCGGTATCTACGGTACGATTTCGCAGGCGGTGGCGCAGCGGACGCAG
GAGATCGGCGTGCGGATGGCGCTGGGCGCGTCTCCGGTCTCGATGATGGCAATGGTCTTCGGCGACGGCATGCGGCTCGC
GGGCGTGGGACTAGCGACGGGATGGATCGCCGGGGCGGCGTTGAGCGGGCTGATGCGCAGCCTACTCTTTGACGTGAAGC
CCTTCGATCCGCTGGTGTTCGGCGCGGGCGCGGCGGTACTGGCGGCCTTTGCTTTGCTGGCCTGCTACGTGCCGGCGCGG
CGCGCCACTCGGGTAGATCCCATGATCGCGTTAAGGCAGGAGTAA

Upstream 100 bases:

>100_bases
GTCACCCGGAAAGATCACGGTGTAGCCGGTGGATCCGGTGGCCGCCGCCGTGTAACCCCGGTAGACTTCGGCTCGCGGTT
CGCTCAGCGCGCCTATCCTG

Downstream 100 bases:

>100_bases
CGCAGTCACGCCGCATTGATTCAGCCCAAAGAAGTGCCTGACTAAGTACTCCTAGTACCTACGTCGCCACAGATAGAACT
CCGTTACTATTCAAGTTACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MIRTRTDAGAMVETLGATIRGVDPEIPTYDMFAMEALVERSTVQRRFVMMLLTGFALAALLLAGVGIYGTISQAVAQRTQ
EIGVRMALGASPVSMMAMVFGDGMRLAGVGLATGWIAGAALSGLMRSLLFDVKPFDPLVFGAGAAVLAAFALLACYVPAR
RATRVDPMIALRQE

Sequences:

>Translated_174_residues
MIRTRTDAGAMVETLGATIRGVDPEIPTYDMFAMEALVERSTVQRRFVMMLLTGFALAALLLAGVGIYGTISQAVAQRTQ
EIGVRMALGASPVSMMAMVFGDGMRLAGVGLATGWIAGAALSGLMRSLLFDVKPFDPLVFGAGAAVLAAFALLACYVPAR
RATRVDPMIALRQE
>Mature_174_residues
MIRTRTDAGAMVETLGATIRGVDPEIPTYDMFAMEALVERSTVQRRFVMMLLTGFALAALLLAGVGIYGTISQAVAQRTQ
EIGVRMALGASPVSMMAMVFGDGMRLAGVGLATGWIAGAALSGLMRSLLFDVKPFDPLVFGAGAAVLAAFALLACYVPAR
RATRVDPMIALRQE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 18373; Mature: 18373

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
7.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTRTDAGAMVETLGATIRGVDPEIPTYDMFAMEALVERSTVQRRFVMMLLTGFALAAL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGVGIYGTISQAVAQRTQEIGVRMALGASPVSMMAMVFGDGMRLAGVGLATGWIAGAA
HHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSGLMRSLLFDVKPFDPLVFGAGAAVLAAFALLACYVPARRATRVDPMIALRQE
HHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MIRTRTDAGAMVETLGATIRGVDPEIPTYDMFAMEALVERSTVQRRFVMMLLTGFALAAL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAGVGIYGTISQAVAQRTQEIGVRMALGASPVSMMAMVFGDGMRLAGVGLATGWIAGAA
HHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSGLMRSLLFDVKPFDPLVFGAGAAVLAAFALLACYVPARRATRVDPMIALRQE
HHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]