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The map label for this gene is 116620779

Identifier: 116620779

GI number: 116620779

Start: 2057045

End: 2058208

Strand: Direct

Name: 116620779

Synonym: Acid_1660

Alternate gene names: NA

Gene position: 2057045-2058208 (Clockwise)

Preceding gene: 116620776

Following gene: 116620780

Centisome position: 20.64

GC content: 61.43

Gene sequence:

>1164_bases
ATGTATATCAAAAAACAACGTTTATTGACTCCTGGCCCGACTCCCCTCTATCCGCCGGCCTTGCACGCAATGATGGCTTC
GGATATGCACCACCGGACCGAGGATTTCCGCAAGGTCTATCGGGCGTGCCTGGCCGATCTCAAGGAGGTCATGGGGACGT
CCAACGACGTGCTCATGTTCGCCGGGTCGGGAACGGGCGCGATGGACGCGTCGGTCTCAAACTTGTTTTCCAAGGGCGAT
AAGGTCATCGTCTGCGTCGCCGGAAAGTTCGGCGAGCGCTGGGCGGACATCGTCAAGGCGTACGGGCTCGATGCCCGCGT
CATCACGGTGCCCTACGGACAGGCAGTGCAGGCGGAGCAGGTGGAAGCCGCGCTCAAGGCCGAGTCCGGCGCAAAGGGTG
TATTCGTACAGGCGTCGGAGACCTCCACCGGCGCGGCGCACGACGTGGAAGCCATGGGGCGCGCGGTGGCGAAGACCGAT
GCCATCTTCGTGGTGGACGCGATCACGGGCTTGGGCACAATGCCGCTCGATATAGACAAGTGGGGCCTCGACGTGGTGAT
CGGTGGATCGCAGAAGGCCTTCATGATCCCGCCGGGACTGGCGTTCATGTCCATCAGTCCCAAGGCGTGGAAGCTCGGCG
AGAGCGGGAACCTGCCGCATTATTACTTCAACCTGAAGAAGGAAAAGAAGAGCGGTGACGCAGGCGAATCCAGCTGGACG
CCCGCGACCTCGCTGATTCTGGCGCTGGGCGAAGCGTTGAAATATGTCAAGCAGATCGGCATGGGGAACCTGATCGCGAA
TGCGCAGATGCTGGCGCACGCCACGCGACTCGCGGCCGGCAAACTCGGACTGGAGCTGTTCTCGGCGGCATCGCCCGGTT
CTTCGGTGACGGCGATCACCGCTCCCAAGGGGCTGGATTCCGGCGTGATCGTGAAGGAATTCCGCAGCCGTTTTGGTTCG
ATCATCGCCAACGGGCAGGGCTCCATGAAGGGACAGATTTTCCGCATCGCGCACCTCGGATACTTCGATTTCGCGGATCT
GTTCGCCATGCTCGCCGGGCTGGAAATTATCTTGAACGCGAACGGTCACCCGGTGCAGTACGGGGCGGGCGTTGCCGCGG
CGCAGGAAGTATACGCACAGGCGACAGTACCAGCGTTGAAATAA

Upstream 100 bases:

>100_bases
AGCGGGCTGCGTCGCCGCTCTTCATGGCGGTGACCATTTCCTGCTGCACCTGATCAATGAGGGGCATGATGTCTGTTATT
CTAGAAGACTACTCCTCACG

Downstream 100 bases:

>100_bases
AATGAACATCCTCATCGCGGAGCCTCTCGCAGCTGCCGGGATCGAGTTATTCCAATCCCAGCCGGGCTGGAACGTCATCG
TTTCCAGTCCCAAGGAGTAC

Product: phosphoserine aminotransferase/L-aspartate aminotransferase

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MYIKKQRLLTPGPTPLYPPALHAMMASDMHHRTEDFRKVYRACLADLKEVMGTSNDVLMFAGSGTGAMDASVSNLFSKGD
KVIVCVAGKFGERWADIVKAYGLDARVITVPYGQAVQAEQVEAALKAESGAKGVFVQASETSTGAAHDVEAMGRAVAKTD
AIFVVDAITGLGTMPLDIDKWGLDVVIGGSQKAFMIPPGLAFMSISPKAWKLGESGNLPHYYFNLKKEKKSGDAGESSWT
PATSLILALGEALKYVKQIGMGNLIANAQMLAHATRLAAGKLGLELFSAASPGSSVTAITAPKGLDSGVIVKEFRSRFGS
IIANGQGSMKGQIFRIAHLGYFDFADLFAMLAGLEIILNANGHPVQYGAGVAAAQEVYAQATVPALK

Sequences:

>Translated_387_residues
MYIKKQRLLTPGPTPLYPPALHAMMASDMHHRTEDFRKVYRACLADLKEVMGTSNDVLMFAGSGTGAMDASVSNLFSKGD
KVIVCVAGKFGERWADIVKAYGLDARVITVPYGQAVQAEQVEAALKAESGAKGVFVQASETSTGAAHDVEAMGRAVAKTD
AIFVVDAITGLGTMPLDIDKWGLDVVIGGSQKAFMIPPGLAFMSISPKAWKLGESGNLPHYYFNLKKEKKSGDAGESSWT
PATSLILALGEALKYVKQIGMGNLIANAQMLAHATRLAAGKLGLELFSAASPGSSVTAITAPKGLDSGVIVKEFRSRFGS
IIANGQGSMKGQIFRIAHLGYFDFADLFAMLAGLEIILNANGHPVQYGAGVAAAQEVYAQATVPALK
>Mature_387_residues
MYIKKQRLLTPGPTPLYPPALHAMMASDMHHRTEDFRKVYRACLADLKEVMGTSNDVLMFAGSGTGAMDASVSNLFSKGD
KVIVCVAGKFGERWADIVKAYGLDARVITVPYGQAVQAEQVEAALKAESGAKGVFVQASETSTGAAHDVEAMGRAVAKTD
AIFVVDAITGLGTMPLDIDKWGLDVVIGGSQKAFMIPPGLAFMSISPKAWKLGESGNLPHYYFNLKKEKKSGDAGESSWT
PATSLILALGEALKYVKQIGMGNLIANAQMLAHATRLAAGKLGLELFSAASPGSSVTAITAPKGLDSGVIVKEFRSRFGS
IIANGQGSMKGQIFRIAHLGYFDFADLFAMLAGLEIILNANGHPVQYGAGVAAAQEVYAQATVPALK

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=350, Percent_Identity=28.2857142857143, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17536281, Length=350, Percent_Identity=28.8571428571429, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6321079, Length=355, Percent_Identity=26.7605633802817, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17530823, Length=350, Percent_Identity=26, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 40834; Mature: 40834

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIKKQRLLTPGPTPLYPPALHAMMASDMHHRTEDFRKVYRACLADLKEVMGTSNDVLMF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
AGSGTGAMDASVSNLFSKGDKVIVCVAGKFGERWADIVKAYGLDARVITVPYGQAVQAEQ
ECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHH
VEAALKAESGAKGVFVQASETSTGAAHDVEAMGRAVAKTDAIFVVDAITGLGTMPLDIDK
HHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCEECC
WGLDVVIGGSQKAFMIPPGLAFMSISPKAWKLGESGNLPHYYFNLKKEKKSGDAGESSWT
CCEEEEECCCCEEEEECCCCEEEEECCCCEECCCCCCCCEEEEEEEECCCCCCCCCCCCC
PATSLILALGEALKYVKQIGMGNLIANAQMLAHATRLAAGKLGLELFSAASPGSSVTAIT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
APKGLDSGVIVKEFRSRFGSIIANGQGSMKGQIFRIAHLGYFDFADLFAMLAGLEIILNA
CCCCCCCCHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEECC
NGHPVQYGAGVAAAQEVYAQATVPALK
CCCEEECCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYIKKQRLLTPGPTPLYPPALHAMMASDMHHRTEDFRKVYRACLADLKEVMGTSNDVLMF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
AGSGTGAMDASVSNLFSKGDKVIVCVAGKFGERWADIVKAYGLDARVITVPYGQAVQAEQ
ECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHH
VEAALKAESGAKGVFVQASETSTGAAHDVEAMGRAVAKTDAIFVVDAITGLGTMPLDIDK
HHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCEECC
WGLDVVIGGSQKAFMIPPGLAFMSISPKAWKLGESGNLPHYYFNLKKEKKSGDAGESSWT
CCEEEEECCCCEEEEECCCCEEEEECCCCEECCCCCCCCEEEEEEEECCCCCCCCCCCCC
PATSLILALGEALKYVKQIGMGNLIANAQMLAHATRLAAGKLGLELFSAASPGSSVTAIT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
APKGLDSGVIVKEFRSRFGSIIANGQGSMKGQIFRIAHLGYFDFADLFAMLAGLEIILNA
CCCCCCCCHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCHHHHHHHHCCEEEEECC
NGHPVQYGAGVAAAQEVYAQATVPALK
CCCEEECCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]