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The map label for this gene is lnt [H]

Identifier: 116620623

GI number: 116620623

Start: 1839945

End: 1841396

Strand: Direct

Name: lnt [H]

Synonym: Acid_1502

Alternate gene names: 116620623

Gene position: 1839945-1841396 (Clockwise)

Preceding gene: 116620622

Following gene: 116620624

Centisome position: 18.46

GC content: 65.36

Gene sequence:

>1452_bases
ATGAACTGGCTCTTGGCGCTGGCGTCCGCCGGGATGCTGGTGCTGGCGTTTCCGCAATTCTCCCTGGTGTGGCTGGCTCC
GGTGGCATTGGCGCCGCTGCTGGTGGCGGTGGCGCGCGAGCCGGAATGGAAGCGTCGTTTCCTGCTGGGATGGGCGGCGG
GAGTGGTGTATTGGTTCGGCGTCTGCTACTGGATTCAGTTCGTGCTTGCGGTGCACGGCGGGGTGGGGAATGCCGCGGGG
TGGGCGTTGTTCCTGCTGTTCTGCGTGCTCAAGGCAATCCACATGGGCGTGTTCGCGGTCTTCGCGGGCATGCTGATGCA
GCGCTGGTGGGCGACTCCCACGGTCGCGGCGCTTTGGGTGGCGGTGGAGGCCACGCACGGATCGCTGGGCTTCGCGTGGC
TGGCGCTGGGGAATGCGGGAATCGACATGGCCAGCCCGCTGAGGTTGGCTCCGATTACCGGCGTCTACGGAATCTCTTTC
GTGTTCGCTCTCATGGGTACGGCGGTGGCGCTGGTGGTGCTGCGGCGCCCGCGCCGCGAACTGCTGTGGATTACTCCCAT
TCTGCTGCTGCCCTTGCTGCCGCAGATGCCTGCGGCGGAGCGCGGGCGCGAAGCGGCGCTGCTGCTGCAGCCCAACATCT
CCGAGACCGAGCAGTGGACCGCGGAGAGCCTGGACCAATTAAAGCGGCGGCAGGTCATGCTCTCACTACGCGGGGCGCTC
GGCGAACCGCAGCCCCCTTCGATTATCGTGTGGCCAGAGGTGCCGGCGCCCTTCTATTACACGGAGGACCCGGCTTTTCG
AGGCTACGTGAACAGCCTGGCGCGCACCGCGAAGGCCTATGTGCTGGCCGGGATTGTGGCCCATACGCCGGGCGGGGTAC
CGTTGAACTCGGCGGCGCTGATCTCTCCGGAGGGCACGCTGGTGAGCCGCTACGACAAAGTGAACCTGGTGCCGTTCGGC
GAGTTTGTGCCGTGGCCGTTCGGCCTGGCGGCCAACAAGATTTCGACCGAGGTGGGCGATTTCGCGGCGGGCTCGCAGGT
GGTGGTGTCGCCTGTGGGAAGTCATCGCATCGGCACGTTCATCTGCTACGAGAGCGTGTTCCCCGGCTTCGTCCGCAAGT
TCGCGGCGGGTGGTGCGGAAGTGTTGTTCAACATCTCCAACGACGGATGGTTCGGAAAAAGCGCGGCGCGCTGGCAGCAT
GTGAACATCGTCCGGATGCGCGCAGCGGAGAACCGGCGATGGATCCTGCGCTCCACGAACGACGGCATCACGGCGGCGAT
CGACCCGGCCGGCCGCTTGCGTGGCACACTCCCGCCGTTTGTGGAGTCGGCGTCGTATACGGGATTCAGTTACCAGAGCG
GGCAGACGATTTATACGCGATTTGGCGATTGGTTCGCGCTCTTGTGCGGCGCCATCGCGATTTTCGGATTGGTGGCGGAG
AGGGTAACGTGA

Upstream 100 bases:

>100_bases
ACGGCATGGGGCTGGGATTCCAGGCGGTATTCAGCGGTCCGTTGGTGCGTAGTTCGTATATGGCCGATCTGGTCAGCGAG
GAGGCCCAGCGGGGTCTCGG

Downstream 100 bases:

>100_bases
GGGCGTGGACCCCGGTGCCGGAAACGCATCAAGACTGCAGTTAGGGCCTTTTCTTATGGAGTGAACCCCAAAAGTGAGAC
AGGAGGAATAGACGCACTTT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MNWLLALASAGMLVLAFPQFSLVWLAPVALAPLLVAVAREPEWKRRFLLGWAAGVVYWFGVCYWIQFVLAVHGGVGNAAG
WALFLLFCVLKAIHMGVFAVFAGMLMQRWWATPTVAALWVAVEATHGSLGFAWLALGNAGIDMASPLRLAPITGVYGISF
VFALMGTAVALVVLRRPRRELLWITPILLLPLLPQMPAAERGREAALLLQPNISETEQWTAESLDQLKRRQVMLSLRGAL
GEPQPPSIIVWPEVPAPFYYTEDPAFRGYVNSLARTAKAYVLAGIVAHTPGGVPLNSAALISPEGTLVSRYDKVNLVPFG
EFVPWPFGLAANKISTEVGDFAAGSQVVVSPVGSHRIGTFICYESVFPGFVRKFAAGGAEVLFNISNDGWFGKSAARWQH
VNIVRMRAAENRRWILRSTNDGITAAIDPAGRLRGTLPPFVESASYTGFSYQSGQTIYTRFGDWFALLCGAIAIFGLVAE
RVT

Sequences:

>Translated_483_residues
MNWLLALASAGMLVLAFPQFSLVWLAPVALAPLLVAVAREPEWKRRFLLGWAAGVVYWFGVCYWIQFVLAVHGGVGNAAG
WALFLLFCVLKAIHMGVFAVFAGMLMQRWWATPTVAALWVAVEATHGSLGFAWLALGNAGIDMASPLRLAPITGVYGISF
VFALMGTAVALVVLRRPRRELLWITPILLLPLLPQMPAAERGREAALLLQPNISETEQWTAESLDQLKRRQVMLSLRGAL
GEPQPPSIIVWPEVPAPFYYTEDPAFRGYVNSLARTAKAYVLAGIVAHTPGGVPLNSAALISPEGTLVSRYDKVNLVPFG
EFVPWPFGLAANKISTEVGDFAAGSQVVVSPVGSHRIGTFICYESVFPGFVRKFAAGGAEVLFNISNDGWFGKSAARWQH
VNIVRMRAAENRRWILRSTNDGITAAIDPAGRLRGTLPPFVESASYTGFSYQSGQTIYTRFGDWFALLCGAIAIFGLVAE
RVT
>Mature_483_residues
MNWLLALASAGMLVLAFPQFSLVWLAPVALAPLLVAVAREPEWKRRFLLGWAAGVVYWFGVCYWIQFVLAVHGGVGNAAG
WALFLLFCVLKAIHMGVFAVFAGMLMQRWWATPTVAALWVAVEATHGSLGFAWLALGNAGIDMASPLRLAPITGVYGISF
VFALMGTAVALVVLRRPRRELLWITPILLLPLLPQMPAAERGREAALLLQPNISETEQWTAESLDQLKRRQVMLSLRGAL
GEPQPPSIIVWPEVPAPFYYTEDPAFRGYVNSLARTAKAYVLAGIVAHTPGGVPLNSAALISPEGTLVSRYDKVNLVPFG
EFVPWPFGLAANKISTEVGDFAAGSQVVVSPVGSHRIGTFICYESVFPGFVRKFAAGGAEVLFNISNDGWFGKSAARWQH
VNIVRMRAAENRRWILRSTNDGITAAIDPAGRLRGTLPPFVESASYTGFSYQSGQTIYTRFGDWFALLCGAIAIFGLVAE
RVT

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=496, Percent_Identity=29.6370967741936, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 52593; Mature: 52593

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWLLALASAGMLVLAFPQFSLVWLAPVALAPLLVAVAREPEWKRRFLLGWAAGVVYWFG
CCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VCYWIQFVLAVHGGVGNAAGWALFLLFCVLKAIHMGVFAVFAGMLMQRWWATPTVAALWV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEE
AVEATHGSLGFAWLALGNAGIDMASPLRLAPITGVYGISFVFALMGTAVALVVLRRPRRE
EEEECCCCCCEEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLWITPILLLPLLPQMPAAERGREAALLLQPNISETEQWTAESLDQLKRRQVMLSLRGAL
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GEPQPPSIIVWPEVPAPFYYTEDPAFRGYVNSLARTAKAYVLAGIVAHTPGGVPLNSAAL
CCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
ISPEGTLVSRYDKVNLVPFGEFVPWPFGLAANKISTEVGDFAAGSQVVVSPVGSHRIGTF
ECCCCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
ICYESVFPGFVRKFAAGGAEVLFNISNDGWFGKSAARWQHVNIVRMRAAENRRWILRSTN
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEECC
DGITAAIDPAGRLRGTLPPFVESASYTGFSYQSGQTIYTRFGDWFALLCGAIAIFGLVAE
CCCEEEECCHHHCCCCCCHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHH
RVT
HCC
>Mature Secondary Structure
MNWLLALASAGMLVLAFPQFSLVWLAPVALAPLLVAVAREPEWKRRFLLGWAAGVVYWFG
CCHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VCYWIQFVLAVHGGVGNAAGWALFLLFCVLKAIHMGVFAVFAGMLMQRWWATPTVAALWV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEE
AVEATHGSLGFAWLALGNAGIDMASPLRLAPITGVYGISFVFALMGTAVALVVLRRPRRE
EEEECCCCCCEEEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLWITPILLLPLLPQMPAAERGREAALLLQPNISETEQWTAESLDQLKRRQVMLSLRGAL
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GEPQPPSIIVWPEVPAPFYYTEDPAFRGYVNSLARTAKAYVLAGIVAHTPGGVPLNSAAL
CCCCCCCEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
ISPEGTLVSRYDKVNLVPFGEFVPWPFGLAANKISTEVGDFAAGSQVVVSPVGSHRIGTF
ECCCCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
ICYESVFPGFVRKFAAGGAEVLFNISNDGWFGKSAARWQHVNIVRMRAAENRRWILRSTN
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEECC
DGITAAIDPAGRLRGTLPPFVESASYTGFSYQSGQTIYTRFGDWFALLCGAIAIFGLVAE
CCCEEEECCHHHCCCCCCHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHH
RVT
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA