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The map label for this gene is tolB [C]

Identifier: 116620550

GI number: 116620550

Start: 1756088

End: 1758643

Strand: Reverse

Name: tolB [C]

Synonym: Acid_1428

Alternate gene names: 116620550

Gene position: 1758643-1756088 (Counterclockwise)

Preceding gene: 116620551

Following gene: 116620549

Centisome position: 17.65

GC content: 62.83

Gene sequence:

>2556_bases
GTGAGCGACATTAAATTAGATTTCCTCAGCAATGAAGCCGTGTCCGGCGAGTTGCTCTCGGAGAGGCTGGCGAGGGGACC
CGTCTCAGCCGATGAGACGTTGCGTCTTGCCATTGAAATTGGAGCTGCGCTGCAGAAGGTGCACAACCGCGGGCGGATCC
ACGGTCAGATTTCTCCGTTTTGCATCGCGATCACGCAACAGGGCGCGCGCATTCTAAAACCGGCTGCCTCGCCTCAGGAC
GCAGCGGCATACCGTGCGCCCGAACAATTGCGGGGCGAAGAACCGGATGTGCGCAGCGACGTATTCTCGTATGGCGCGGT
GGTCTATGAGATCGCGAGCGGCCAGCGCGCATTTTCGGGGAGCGGCGCGGAGTTGGCGCAGCGGATCGCGAAGCAGACTC
CGGCGGTGCTCGGCGGACAATCGCCGGTTTACTGCACGTTGGAAAAGGTGATCGCAGGCTGCATGGAAAAGGAAGCCGGC
CGCCGGCGGCAGCGAGTGCAAAATGCTGTGATCGAGTTGAAGTTGTCGGGCGCGCAGCCGCGCTCCACCGAGCTCGTTTT
GCAGCGGCCGATCTACCACGCGCCGTCGCCCTCCCCAATACTAAAAGAAGAAGTGCTGCCTCCGCTGCCTCCGCCTTCGC
TGGAGAACGTCGAGGCGATGGCCCCGCCGGTTGCTTTACCGAAGCCGCAGGCGCCAGCCATGCCGCATCCGGCTATCCAT
GTCCCACACCCGGCACTTGCGTATGCGGCGCAGGCGAGGGCGGTTTACGGCACGACATTCCGACGGCGTTTCGGAACGAT
CGGTGTCGCGATACTGGCACTGGCGGCCACTTCGGTAGCGGCGGTCATCTACCTGAACAAGAAGCCGGCGCCTCCGGTGG
TGAAGTTCTCAGTTTCGCAGCCCGAACACACCAGCTACCCCGGAATGCCCTCGGTTTCTCCGGACGGACGCTATCTGACT
TTTTCCGCGGTTGGCCCCGAAGGCAAGCGCATGTTGTGGCTGCGTCCGCTGGATGCGCTGCACGCCACGGTAATTCAGGG
GTCGGAGGGCGCATCGGCGCCGTTCTGGTCGCCAGATAGCCAGATGATCGCCTTCTTCGGCGGCAAGAACCTGATGAAGG
TGCGGATCTCGGGCGGCAGGCCGGAAACGATCTGTCCGGCGGAGGCCATGCCGGGCGGCGGAGCGTGGAACACGGACGGC
ACGATTCTATTTTCGCCGAGCCTCTCCGAAGGCTTTTACAAAGTCCCGGCGACGGGCGGCAAGCCGCAACTCGTCTTCAA
GCTGGATGAGAGCAAATCCGAGCGCGGCGATGTCTGGCCGCAGTTCCTCCCGGACAGCAAGCATTTCGTGTTCTACCAGC
AGACGGACCTGGCGGAGACCTCCGGCGTGTACGCGGGTTCGATGGATCCGCCGGAGTATCACCGGCTATTCGCCAGCCAG
ACCAACGCGGTGTATTCGGCTACGGACCCGAATTCGCCGAAGACGGGGCACCTGCTCTACATCAACGAGCGCAACTTGAC
GGCGATGGCGTTCAACGCCGGTAAATTGGAAGTCAGCGGTGACCCCATTACGCTGGCGACCGACATAGGCGCGGTGCGCA
GCCTGGCGCTGGCGCCGATCTCGGTATCGGCGACCGGCGTATTGGTGTATCAAGGAGTGGGGCAGCCCACGAGACAGATG
GTGTGGATGGATCGCAGCGGGAAGCAGATCGCATTGACGGGTGAACCGGGCGAGTGGGGTCCGGGCCGCATTTCTCCGGA
CGGAAACCGCGCCGCCGCCGGCAAGCTCGGGCCGGACGGCAGGAATGCGCATCTGTGGCTGCTGGACCTGAGCGGCGCCG
CCGAGCCGGTATCGTCGGAATCCGGGCCGCACGAAGGGTCGCCGGTGTGGTCTCCGGACGGCGCGAAGCTCGCGTATTTC
GCCAGGCAGGGTGACATCTACGACATTTACTCGCGGTCCGCGCTGCCGGGGAGTCGGCCGGAGCTACTGCTCAAGAGCGA
CGTGAACAAGTACCCGACGGACTGGACTCACGATGGCAAGTACCTGATCTATGGCCTCACAGGGCGAGGCACGCATCTCG
ATGTTTGGGGCCTTGCGGTTGGCGACCGGCGGTCTGCGCCGATTCTGGATACGGTTTTCTCGGAAGGCTTCGCCTCGGTA
TCGCCGGACGGCAAATGGCTGGCTTACCAATCCGATCAATCGGGACGCACTGAGGTCTACGTACAGCAATTCGACGGCTT
GAGCAACGGCACCAAGCGGCGATGGATGGTATCGAAGAGCGGCGGATTACCGCGCTGGCGCTCCGATAGCAACGAACTGT
TCTATATGACACCCGATGGGAGGATGATGAGCGTTGCGATTCGAATCGGCGCCGATGGCAGCATCGAAGCGGGCGCGCCG
CAGCCGCTGTTCCAGACACGCCCGGTTCCCAAGACCTGGAACCTTTACGACGTGTCACCAGACGGGCAGCGCTTCCTGCT
CAACCTTCCGCTTGAGTGGACCAGCTCCGCACCCATCACGGTGATCACCAACTGGACCGAAAAGCTCAAAGAGTAG

Upstream 100 bases:

>100_bases
CCAAAAGGTTATTGCTGTCGCAAAGGGCTCTTAAGTAAAATCGTTGGACGGAAAGAAATATTCCGGTTTTTCAGTTTGCC
GGAAGGAATTGTAAGGGGCC

Downstream 100 bases:

>100_bases
TTTATTTTCAACAGCTTAGACGCAACCTGAATAGTGCAGGGCGGGTGATATAATTAAAGAGCACCCCACCTGCACGGAAG
AGAGCTTGAAAACCGAAACG

Product: WD40 domain-containing protein

Products: NA

Alternate protein names: Protein Kinase; TPR Repeat-Containing Serine/Threonin Protein Kinase; WD40 Domain-Containing Protein; Serine/Threonine Protein Kinase-Like Protein; Serine/Threonine-Protein Kinase; Serine/Threonine Kinase; PASTA Domain-Containing Serine/Threonine Protein Kinase; Serine-Threonine Protein Kinase; Tyrosine Protein KinaseSerine/Threonine Protein Kinase; Protein Tyrosine Kinase Family; WD-40 Repeat-Containing Serine/Threonin Protein Kinase

Number of amino acids: Translated: 851; Mature: 850

Protein sequence:

>851_residues
MSDIKLDFLSNEAVSGELLSERLARGPVSADETLRLAIEIGAALQKVHNRGRIHGQISPFCIAITQQGARILKPAASPQD
AAAYRAPEQLRGEEPDVRSDVFSYGAVVYEIASGQRAFSGSGAELAQRIAKQTPAVLGGQSPVYCTLEKVIAGCMEKEAG
RRRQRVQNAVIELKLSGAQPRSTELVLQRPIYHAPSPSPILKEEVLPPLPPPSLENVEAMAPPVALPKPQAPAMPHPAIH
VPHPALAYAAQARAVYGTTFRRRFGTIGVAILALAATSVAAVIYLNKKPAPPVVKFSVSQPEHTSYPGMPSVSPDGRYLT
FSAVGPEGKRMLWLRPLDALHATVIQGSEGASAPFWSPDSQMIAFFGGKNLMKVRISGGRPETICPAEAMPGGGAWNTDG
TILFSPSLSEGFYKVPATGGKPQLVFKLDESKSERGDVWPQFLPDSKHFVFYQQTDLAETSGVYAGSMDPPEYHRLFASQ
TNAVYSATDPNSPKTGHLLYINERNLTAMAFNAGKLEVSGDPITLATDIGAVRSLALAPISVSATGVLVYQGVGQPTRQM
VWMDRSGKQIALTGEPGEWGPGRISPDGNRAAAGKLGPDGRNAHLWLLDLSGAAEPVSSESGPHEGSPVWSPDGAKLAYF
ARQGDIYDIYSRSALPGSRPELLLKSDVNKYPTDWTHDGKYLIYGLTGRGTHLDVWGLAVGDRRSAPILDTVFSEGFASV
SPDGKWLAYQSDQSGRTEVYVQQFDGLSNGTKRRWMVSKSGGLPRWRSDSNELFYMTPDGRMMSVAIRIGADGSIEAGAP
QPLFQTRPVPKTWNLYDVSPDGQRFLLNLPLEWTSSAPITVITNWTEKLKE

Sequences:

>Translated_851_residues
MSDIKLDFLSNEAVSGELLSERLARGPVSADETLRLAIEIGAALQKVHNRGRIHGQISPFCIAITQQGARILKPAASPQD
AAAYRAPEQLRGEEPDVRSDVFSYGAVVYEIASGQRAFSGSGAELAQRIAKQTPAVLGGQSPVYCTLEKVIAGCMEKEAG
RRRQRVQNAVIELKLSGAQPRSTELVLQRPIYHAPSPSPILKEEVLPPLPPPSLENVEAMAPPVALPKPQAPAMPHPAIH
VPHPALAYAAQARAVYGTTFRRRFGTIGVAILALAATSVAAVIYLNKKPAPPVVKFSVSQPEHTSYPGMPSVSPDGRYLT
FSAVGPEGKRMLWLRPLDALHATVIQGSEGASAPFWSPDSQMIAFFGGKNLMKVRISGGRPETICPAEAMPGGGAWNTDG
TILFSPSLSEGFYKVPATGGKPQLVFKLDESKSERGDVWPQFLPDSKHFVFYQQTDLAETSGVYAGSMDPPEYHRLFASQ
TNAVYSATDPNSPKTGHLLYINERNLTAMAFNAGKLEVSGDPITLATDIGAVRSLALAPISVSATGVLVYQGVGQPTRQM
VWMDRSGKQIALTGEPGEWGPGRISPDGNRAAAGKLGPDGRNAHLWLLDLSGAAEPVSSESGPHEGSPVWSPDGAKLAYF
ARQGDIYDIYSRSALPGSRPELLLKSDVNKYPTDWTHDGKYLIYGLTGRGTHLDVWGLAVGDRRSAPILDTVFSEGFASV
SPDGKWLAYQSDQSGRTEVYVQQFDGLSNGTKRRWMVSKSGGLPRWRSDSNELFYMTPDGRMMSVAIRIGADGSIEAGAP
QPLFQTRPVPKTWNLYDVSPDGQRFLLNLPLEWTSSAPITVITNWTEKLKE
>Mature_850_residues
SDIKLDFLSNEAVSGELLSERLARGPVSADETLRLAIEIGAALQKVHNRGRIHGQISPFCIAITQQGARILKPAASPQDA
AAYRAPEQLRGEEPDVRSDVFSYGAVVYEIASGQRAFSGSGAELAQRIAKQTPAVLGGQSPVYCTLEKVIAGCMEKEAGR
RRQRVQNAVIELKLSGAQPRSTELVLQRPIYHAPSPSPILKEEVLPPLPPPSLENVEAMAPPVALPKPQAPAMPHPAIHV
PHPALAYAAQARAVYGTTFRRRFGTIGVAILALAATSVAAVIYLNKKPAPPVVKFSVSQPEHTSYPGMPSVSPDGRYLTF
SAVGPEGKRMLWLRPLDALHATVIQGSEGASAPFWSPDSQMIAFFGGKNLMKVRISGGRPETICPAEAMPGGGAWNTDGT
ILFSPSLSEGFYKVPATGGKPQLVFKLDESKSERGDVWPQFLPDSKHFVFYQQTDLAETSGVYAGSMDPPEYHRLFASQT
NAVYSATDPNSPKTGHLLYINERNLTAMAFNAGKLEVSGDPITLATDIGAVRSLALAPISVSATGVLVYQGVGQPTRQMV
WMDRSGKQIALTGEPGEWGPGRISPDGNRAAAGKLGPDGRNAHLWLLDLSGAAEPVSSESGPHEGSPVWSPDGAKLAYFA
RQGDIYDIYSRSALPGSRPELLLKSDVNKYPTDWTHDGKYLIYGLTGRGTHLDVWGLAVGDRRSAPILDTVFSEGFASVS
PDGKWLAYQSDQSGRTEVYVQQFDGLSNGTKRRWMVSKSGGLPRWRSDSNELFYMTPDGRMMSVAIRIGADGSIEAGAPQ
PLFQTRPVPKTWNLYDVSPDGQRFLLNLPLEWTSSAPITVITNWTEKLKE

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 91836; Mature: 91705

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIKLDFLSNEAVSGELLSERLARGPVSADETLRLAIEIGAALQKVHNRGRIHGQISPF
CCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEECCCCE
CIAITQQGARILKPAASPQDAAAYRAPEQLRGEEPDVRSDVFSYGAVVYEIASGQRAFSG
EEEEECCCCEEECCCCCCCHHHHHCCCHHHCCCCCCHHHHHHHHCEEEEEECCCCEECCC
SGAELAQRIAKQTPAVLGGQSPVYCTLEKVIAGCMEKEAGRRRQRVQNAVIELKLSGAQP
CCHHHHHHHHHHCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCC
RSTELVLQRPIYHAPSPSPILKEEVLPPLPPPSLENVEAMAPPVALPKPQAPAMPHPAIH
CCCEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEE
VPHPALAYAAQARAVYGTTFRRRFGTIGVAILALAATSVAAVIYLNKKPAPPVVKFSVSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEEEECCC
PEHTSYPGMPSVSPDGRYLTFSAVGPEGKRMLWLRPLDALHATVIQGSEGASAPFWSPDS
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHEEEEEECCCCCCCCCCCCCC
QMIAFFGGKNLMKVRISGGRPETICPAEAMPGGGAWNTDGTILFSPSLSEGFYKVPATGG
CEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCC
KPQLVFKLDESKSERGDVWPQFLPDSKHFVFYQQTDLAETSGVYAGSMDPPEYHRLFASQ
CCEEEEEECCCCCCCCCCCHHHCCCCCCEEEEEECCCCHHCCEEECCCCCHHHHHHHHHC
TNAVYSATDPNSPKTGHLLYINERNLTAMAFNAGKLEVSGDPITLATDIGAVRSLALAPI
CCEEEECCCCCCCCCCEEEEEECCCEEEEEEECCEEEECCCCEEEEECHHHHHHHHCCCE
SVSATGVLVYQGVGQPTRQMVWMDRSGKQIALTGEPGEWGPGRISPDGNRAAAGKLGPDG
EECCCEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCC
RNAHLWLLDLSGAAEPVSSESGPHEGSPVWSPDGAKLAYFARQGDIYDIYSRSALPGSRP
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCC
ELLLKSDVNKYPTDWTHDGKYLIYGLTGRGTHLDVWGLAVGDRRSAPILDTVFSEGFASV
CEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHCCCCCC
SPDGKWLAYQSDQSGRTEVYVQQFDGLSNGTKRRWMVSKSGGLPRWRSDSNELFYMTPDG
CCCCCEEEEECCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCC
RMMSVAIRIGADGSIEAGAPQPLFQTRPVPKTWNLYDVSPDGQRFLLNLPLEWTSSAPIT
CEEEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCEE
VITNWTEKLKE
EEECCHHHHCC
>Mature Secondary Structure 
SDIKLDFLSNEAVSGELLSERLARGPVSADETLRLAIEIGAALQKVHNRGRIHGQISPF
CCEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEECCCCE
CIAITQQGARILKPAASPQDAAAYRAPEQLRGEEPDVRSDVFSYGAVVYEIASGQRAFSG
EEEEECCCCEEECCCCCCCHHHHHCCCHHHCCCCCCHHHHHHHHCEEEEEECCCCEECCC
SGAELAQRIAKQTPAVLGGQSPVYCTLEKVIAGCMEKEAGRRRQRVQNAVIELKLSGAQP
CCHHHHHHHHHHCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCC
RSTELVLQRPIYHAPSPSPILKEEVLPPLPPPSLENVEAMAPPVALPKPQAPAMPHPAIH
CCCEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEE
VPHPALAYAAQARAVYGTTFRRRFGTIGVAILALAATSVAAVIYLNKKPAPPVVKFSVSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEEEECCC
PEHTSYPGMPSVSPDGRYLTFSAVGPEGKRMLWLRPLDALHATVIQGSEGASAPFWSPDS
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHEEEEEECCCCCCCCCCCCCC
QMIAFFGGKNLMKVRISGGRPETICPAEAMPGGGAWNTDGTILFSPSLSEGFYKVPATGG
CEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCCC
KPQLVFKLDESKSERGDVWPQFLPDSKHFVFYQQTDLAETSGVYAGSMDPPEYHRLFASQ
CCEEEEEECCCCCCCCCCCHHHCCCCCCEEEEEECCCCHHCCEEECCCCCHHHHHHHHHC
TNAVYSATDPNSPKTGHLLYINERNLTAMAFNAGKLEVSGDPITLATDIGAVRSLALAPI
CCEEEECCCCCCCCCCEEEEEECCCEEEEEEECCEEEECCCCEEEEECHHHHHHHHCCCE
SVSATGVLVYQGVGQPTRQMVWMDRSGKQIALTGEPGEWGPGRISPDGNRAAAGKLGPDG
EECCCEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCC
RNAHLWLLDLSGAAEPVSSESGPHEGSPVWSPDGAKLAYFARQGDIYDIYSRSALPGSRP
CCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCC
ELLLKSDVNKYPTDWTHDGKYLIYGLTGRGTHLDVWGLAVGDRRSAPILDTVFSEGFASV
CEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCHHHHHHHCCCCCC
SPDGKWLAYQSDQSGRTEVYVQQFDGLSNGTKRRWMVSKSGGLPRWRSDSNELFYMTPDG
CCCCCEEEEECCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCC
RMMSVAIRIGADGSIEAGAPQPLFQTRPVPKTWNLYDVSPDGQRFLLNLPLEWTSSAPIT
CEEEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCEE
VITNWTEKLKE
EEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA