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The map label for this gene is cyaA [H]

Identifier: 116620542

GI number: 116620542

Start: 1747197

End: 1748147

Strand: Direct

Name: cyaA [H]

Synonym: Acid_1420

Alternate gene names: 116620542

Gene position: 1747197-1748147 (Clockwise)

Preceding gene: 116620540

Following gene: 116620544

Centisome position: 17.53

GC content: 63.09

Gene sequence:

>951_bases
GTGACTCCAGCCGTTTTTAATCCGTTCCTGACAGTGGAAGCCAACGGCCGCCGATTTCCGCTCGGCGAGGGACAATCCTG
GGCGATCGGCCGCGGCGACGGCTGCGCTGTCATGCTCGACAGCCGTTCGGTCTCGCGCCTGCATGCCCTCATTCAGCGCC
GCGATACCGGCGACCTCGCCCTGGTAGACCTGGGGAGCCGCAACGGTTCCTTCGTGAATGGCCGCCGCGTCAGCTTTCCC
GTGGTACTCAATGATAGCGACAAACTGGTCTTCGGCGACCAGGACCTCGTCTTCCGCAACCCGGCTGGTTCCGAAGCCGT
ACTCCGCAACTCCGGAGTTGACCTGAGAAACGAACCCACCACCGCGCTCCACACCAACAGCCTGACTACCATCATGGTGG
TGGATATCCGCGATTTCACCCCGCTCGCGCGCACACTGCCGGAAGCCCTGCTTTCGCAGACGATCGGTACCTGGTTTTTG
CGCAGCGGACAGATCGTGCAGCGCCTTGGCAGCTGGGCCCAGAAATATATCGGCGATGCGGTGATGGCGGTGTGGGTTCA
CGATCAGCGCGAACAATTGGGCGCCGACCTGGTGCGCGTGTTGCGCGCCGTCACCGAGATCAGCGCCGCTACTGCCGAGA
TCAGCCGGACCCTGGAACTCCCCGTTCCGCTGCGCATTGGCGCCGGCGTCAATACCGGGCTGGCGATCCTGGGTGGCACG
GATTACACCGTGCTCGGCGATACCGTGAACGTGGCTTTCCGCCTGGAATCGGCCACCAAGTCGATCGGCTTGGGCGTCGC
GATCGGCGCGCCTTCCTATTTGGGTCTCGGCGAAACCGCCCGCGCAGGCTTCGTCCGCAAGGAAGTGGAGCTCAAGGGCT
ACGAAGGCTCCAGCATCGCATGGGCGATTTCTTTCGAAGACCTGAAAAACAACCTGTACCGCGCCGGCTAA

Upstream 100 bases:

>100_bases
TACCTCTTGTTCTAGTACAAAACACTGGATTTAGTCCTTTTGCCCGGTATTCCCGGGAGCCAACAAGCGAATTCAACCCT
GGCTTGCTAAATTGGGTCTA

Downstream 100 bases:

>100_bases
GTTGTTTTCACCGCGGCGCCGAAGCCTTGGCCGAACTCAATCCGCGCAACTGCTCCAGTTTTCGGTTCTTGCGCAAGTCG
TAGACGTACATCGACCAACC

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTPAVFNPFLTVEANGRRFPLGEGQSWAIGRGDGCAVMLDSRSVSRLHALIQRRDTGDLALVDLGSRNGSFVNGRRVSFP
VVLNDSDKLVFGDQDLVFRNPAGSEAVLRNSGVDLRNEPTTALHTNSLTTIMVVDIRDFTPLARTLPEALLSQTIGTWFL
RSGQIVQRLGSWAQKYIGDAVMAVWVHDQREQLGADLVRVLRAVTEISAATAEISRTLELPVPLRIGAGVNTGLAILGGT
DYTVLGDTVNVAFRLESATKSIGLGVAIGAPSYLGLGETARAGFVRKEVELKGYEGSSIAWAISFEDLKNNLYRAG

Sequences:

>Translated_316_residues
MTPAVFNPFLTVEANGRRFPLGEGQSWAIGRGDGCAVMLDSRSVSRLHALIQRRDTGDLALVDLGSRNGSFVNGRRVSFP
VVLNDSDKLVFGDQDLVFRNPAGSEAVLRNSGVDLRNEPTTALHTNSLTTIMVVDIRDFTPLARTLPEALLSQTIGTWFL
RSGQIVQRLGSWAQKYIGDAVMAVWVHDQREQLGADLVRVLRAVTEISAATAEISRTLELPVPLRIGAGVNTGLAILGGT
DYTVLGDTVNVAFRLESATKSIGLGVAIGAPSYLGLGETARAGFVRKEVELKGYEGSSIAWAISFEDLKNNLYRAG
>Mature_315_residues
TPAVFNPFLTVEANGRRFPLGEGQSWAIGRGDGCAVMLDSRSVSRLHALIQRRDTGDLALVDLGSRNGSFVNGRRVSFPV
VLNDSDKLVFGDQDLVFRNPAGSEAVLRNSGVDLRNEPTTALHTNSLTTIMVVDIRDFTPLARTLPEALLSQTIGTWFLR
SGQIVQRLGSWAQKYIGDAVMAVWVHDQREQLGADLVRVLRAVTEISAATAEISRTLELPVPLRIGAGVNTGLAILGGTD
YTVLGDTVNVAFRLESATKSIGLGVAIGAPSYLGLGETARAGFVRKEVELKGYEGSSIAWAISFEDLKNNLYRAG

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 34026; Mature: 33895

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50006 FHA_DOMAIN ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAVFNPFLTVEANGRRFPLGEGQSWAIGRGDGCAVMLDSRSVSRLHALIQRRDTGDLA
CCCCEECCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCEE
LVDLGSRNGSFVNGRRVSFPVVLNDSDKLVFGDQDLVFRNPAGSEAVLRNSGVDLRNEPT
EEEECCCCCCEECCCEEEEEEEECCCCCEEECCCCEEEECCCCCCCEEECCCCCCCCCCC
TALHTNSLTTIMVVDIRDFTPLARTLPEALLSQTIGTWFLRSGQIVQRLGSWAQKYIGDA
CEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCE
VMAVWVHDQREQLGADLVRVLRAVTEISAATAEISRTLELPVPLRIGAGVNTGLAILGGT
EEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCCEEEECCC
DYTVLGDTVNVAFRLESATKSIGLGVAIGAPSYLGLGETARAGFVRKEVELKGYEGSSIA
CEEEECCEEEEEEEEECCCHHCCCEEEECCCCCCCCCCHHHCCCEEEEEEEECCCCCEEE
WAISFEDLKNNLYRAG
EEEEHHHHHHHHCCCC
>Mature Secondary Structure 
TPAVFNPFLTVEANGRRFPLGEGQSWAIGRGDGCAVMLDSRSVSRLHALIQRRDTGDLA
CCCEECCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCEE
LVDLGSRNGSFVNGRRVSFPVVLNDSDKLVFGDQDLVFRNPAGSEAVLRNSGVDLRNEPT
EEEECCCCCCEECCCEEEEEEEECCCCCEEECCCCEEEECCCCCCCEEECCCCCCCCCCC
TALHTNSLTTIMVVDIRDFTPLARTLPEALLSQTIGTWFLRSGQIVQRLGSWAQKYIGDA
CEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCE
VMAVWVHDQREQLGADLVRVLRAVTEISAATAEISRTLELPVPLRIGAGVNTGLAILGGT
EEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEECCCCCCCEEEECCC
DYTVLGDTVNVAFRLESATKSIGLGVAIGAPSYLGLGETARAGFVRKEVELKGYEGSSIA
CEEEECCEEEEEEEEECCCHHCCCEEEECCCCCCCCCCHHHCCCEEEEEEEECCCCCEEE
WAISFEDLKNNLYRAG
EEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]