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The map label for this gene is blaR1 [H]

Identifier: 116620159

GI number: 116620159

Start: 1276257

End: 1278287

Strand: Direct

Name: blaR1 [H]

Synonym: Acid_1032

Alternate gene names: 116620159

Gene position: 1276257-1278287 (Clockwise)

Preceding gene: 116620158

Following gene: 116620162

Centisome position: 12.81

GC content: 64.7

Gene sequence:

>2031_bases
ATGAGCACCCATCTCATCTGGGACAACCTGGTGGCCTACAGCATGCAGATCGGCCTGCTGATCGGGCTCGCCGCGTTCGT
TCCCGCATTGCTCCGCCTCAAAGTCCCGCATACGAAACTCGCCTACTGGCAGATCCTGCTGGCCACTTGTCTGCTGCTGC
CCGCGGTGCGTCCGTGGAAGCAGGCGATGCTCACCGTCAGCCGTCCCGTGTTCAGCAACATCGCCGACCTGCCGCCCATG
CAACCCATGCCCCCCACTTCGCTCTCCACGAGCGAGATCGCACTCGCGATCCTGGGCGCCGGGATCGTCCTTCGCCTGTG
CTGGTTCGCCGTGGCTTTCCTGCGCCTGGGCCGCCTGCGCCACCACTCGCAGCCGCTAACCCCGCCGACCGCCTGGAGCG
TGGAGGCCGATATCCGCGTCTCCGAGGCCATCTCCAGCCCGGTCACCTTCGGCTTTCTGCGTCCCGTGGTTCTTCTGCCA
GCGAATTTCTCCGAGCTGGACGTGCAGATTCAGGACGCCATTCTCTGCCACGAAGTTCTTCACGTCCGCCGCCGCGACTG
GCTCTTCACGCTCGGCGAAGAGCTGGTTCGCAGCCTGTTCTGGTTTCATCCCGCGATCTGGTGGCTGCTTGGCGAGATCG
GTCTCGCCCGCGAGCAGGAAGTGGATCGCCTGGTGGTCGAGCTAACCAAATCGCGCGAGGGCTATGTGGACGCCCTGCTC
GCGATTGCCGGCGCAGCTCCCCGGCTCGACCTGGCCCCCGCGCCGCTCTTCTTGCGCAAGCGGCACTTAAAGCAGCGAGT
AGTCTCGATCATGAAGGAGGTACGAATGTCGAAAACGAGATCATTTTCCGCGCTCGCCGCGGGGCTGGGTTTCCTGGCCG
CCGCGTGCTGGCTCGTCACCGCAACTTTCCCGCTGGCGGCCGCGCCGCAGAGCGTTAACGATTTTCCCGGAGTCACGGTC
GATACCGGCGGCCCCGTTATGCACCGCACTGCCGTCATTTACCCGGACGCGGCGCGGCTCCACAACATTCAGGGCGTCGT
GGTCGTGGAAGCTTCGCTCGATAGCAGCGGCAACGTCACCGACACCCGCGTCCTTAGCGGTCCGCCCGAACTCCGCCGCG
CCGCCCAGCAGGCCGTATTGCAATGGCACTTCTCGATGGAAGGCTCTTCCAACACGCGGCAGGTGAAGATCAACTTCGAG
CTGCCTTCCGGGCAGCGTGCCCCAGCCACCGTCGTCACCGTGAATCCTCCCGCCATGGGCGCCGTGAACGATCCCGAAAA
GATCGCCGCCGCCGAAGCCAAAATCCGCGCGTTGCGTTCCCAGATCACCGACCAGACCGCCGCGCTCCGCTCCTCGCAGG
ACGAGGCCGCGCGCCAGCAGGCCGCCGCCAAATTGAGCGAGCTGCAGGAAAACGTCAGCAACCTGCAGCGCAATCTCGGC
CCCGCCTCCCTGGCCGGCAAGCGCCTCGCACGCATTAACGTCATGGGTCTGAGCGACCAGGTCCGCGACCAGTTGCTGTC
GCGCCTCCCCGTCCACACGGGCGACACTCTGTCCGCCGATTCCTACGACCTCACCAGCAAGGCCGTCAGGGAATTCGACG
AGCACATGTTCGTCAGCCAGAGCGCCAATTCCCAAACCGGCGAAGTGGCCTTCACCATCGTGCAGGGCGGCGGCAGCATC
GCCTCCGTGAGCATGACCGCACCGACCACACCCGCGACTCCCGGCGTCAAGCGCATCACCATCGGCGGCAACGTCCAGCA
GACAAAACTGGTCTCCCAGGCTCGCCCGGTGTATCCCCCGCTCGCCAAGCAGGCGCGCATCTCCGGCGTAGTCCACCTGC
AAGCCGTCATCGCCAAGGACGGCAACGTGATGGATCTCAAAGTGATCAGCGGACATCCCCTGCTCATCCCCGCCGCGCTC
GAGGCGGTGAAAACATGGGTCTATCAGACCACTCTCCTCAACGGCGAACCTGTCGAAGTGGTCACCCAAATCGACGTCAA
CTTCACCCTCTCCGAAGAAGGCGGCAACTAA

Upstream 100 bases:

>100_bases
TTTTCAACGGCTCGGCCGAGCCCCTGCTGGTGCACCTGGTCGAAGAGCACGATCTCTCTCCGGAAGAACTCGACGAGATC
GCGCGCATACGGAGGAAGCC

Downstream 100 bases:

>100_bases
CTCACAACGAGCCGCGACCGTGAGGGAGCGCTACCCGGAAGCGCTCCCTCACGGTCGCGGCTCGTTCTTTACTCGTACCT
CAGCACTTCCGCCGGCGCGA

Product: TonB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MSTHLIWDNLVAYSMQIGLLIGLAAFVPALLRLKVPHTKLAYWQILLATCLLLPAVRPWKQAMLTVSRPVFSNIADLPPM
QPMPPTSLSTSEIALAILGAGIVLRLCWFAVAFLRLGRLRHHSQPLTPPTAWSVEADIRVSEAISSPVTFGFLRPVVLLP
ANFSELDVQIQDAILCHEVLHVRRRDWLFTLGEELVRSLFWFHPAIWWLLGEIGLAREQEVDRLVVELTKSREGYVDALL
AIAGAAPRLDLAPAPLFLRKRHLKQRVVSIMKEVRMSKTRSFSALAAGLGFLAAACWLVTATFPLAAAPQSVNDFPGVTV
DTGGPVMHRTAVIYPDAARLHNIQGVVVVEASLDSSGNVTDTRVLSGPPELRRAAQQAVLQWHFSMEGSSNTRQVKINFE
LPSGQRAPATVVTVNPPAMGAVNDPEKIAAAEAKIRALRSQITDQTAALRSSQDEAARQQAAAKLSELQENVSNLQRNLG
PASLAGKRLARINVMGLSDQVRDQLLSRLPVHTGDTLSADSYDLTSKAVREFDEHMFVSQSANSQTGEVAFTIVQGGGSI
ASVSMTAPTTPATPGVKRITIGGNVQQTKLVSQARPVYPPLAKQARISGVVHLQAVIAKDGNVMDLKVISGHPLLIPAAL
EAVKTWVYQTTLLNGEPVEVVTQIDVNFTLSEEGGN

Sequences:

>Translated_676_residues
MSTHLIWDNLVAYSMQIGLLIGLAAFVPALLRLKVPHTKLAYWQILLATCLLLPAVRPWKQAMLTVSRPVFSNIADLPPM
QPMPPTSLSTSEIALAILGAGIVLRLCWFAVAFLRLGRLRHHSQPLTPPTAWSVEADIRVSEAISSPVTFGFLRPVVLLP
ANFSELDVQIQDAILCHEVLHVRRRDWLFTLGEELVRSLFWFHPAIWWLLGEIGLAREQEVDRLVVELTKSREGYVDALL
AIAGAAPRLDLAPAPLFLRKRHLKQRVVSIMKEVRMSKTRSFSALAAGLGFLAAACWLVTATFPLAAAPQSVNDFPGVTV
DTGGPVMHRTAVIYPDAARLHNIQGVVVVEASLDSSGNVTDTRVLSGPPELRRAAQQAVLQWHFSMEGSSNTRQVKINFE
LPSGQRAPATVVTVNPPAMGAVNDPEKIAAAEAKIRALRSQITDQTAALRSSQDEAARQQAAAKLSELQENVSNLQRNLG
PASLAGKRLARINVMGLSDQVRDQLLSRLPVHTGDTLSADSYDLTSKAVREFDEHMFVSQSANSQTGEVAFTIVQGGGSI
ASVSMTAPTTPATPGVKRITIGGNVQQTKLVSQARPVYPPLAKQARISGVVHLQAVIAKDGNVMDLKVISGHPLLIPAAL
EAVKTWVYQTTLLNGEPVEVVTQIDVNFTLSEEGGN
>Mature_675_residues
STHLIWDNLVAYSMQIGLLIGLAAFVPALLRLKVPHTKLAYWQILLATCLLLPAVRPWKQAMLTVSRPVFSNIADLPPMQ
PMPPTSLSTSEIALAILGAGIVLRLCWFAVAFLRLGRLRHHSQPLTPPTAWSVEADIRVSEAISSPVTFGFLRPVVLLPA
NFSELDVQIQDAILCHEVLHVRRRDWLFTLGEELVRSLFWFHPAIWWLLGEIGLAREQEVDRLVVELTKSREGYVDALLA
IAGAAPRLDLAPAPLFLRKRHLKQRVVSIMKEVRMSKTRSFSALAAGLGFLAAACWLVTATFPLAAAPQSVNDFPGVTVD
TGGPVMHRTAVIYPDAARLHNIQGVVVVEASLDSSGNVTDTRVLSGPPELRRAAQQAVLQWHFSMEGSSNTRQVKINFEL
PSGQRAPATVVTVNPPAMGAVNDPEKIAAAEAKIRALRSQITDQTAALRSSQDEAARQQAAAKLSELQENVSNLQRNLGP
ASLAGKRLARINVMGLSDQVRDQLLSRLPVHTGDTLSADSYDLTSKAVREFDEHMFVSQSANSQTGEVAFTIVQGGGSIA
SVSMTAPTTPATPGVKRITIGGNVQQTKLVSQARPVYPPLAKQARISGVVHLQAVIAKDGNVMDLKVISGHPLLIPAALE
AVKTWVYQTTLLNGEPVEVVTQIDVNFTLSEEGGN

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 73319; Mature: 73188

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHLIWDNLVAYSMQIGLLIGLAAFVPALLRLKVPHTKLAYWQILLATCLLLPAVRPWK
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHH
QAMLTVSRPVFSNIADLPPMQPMPPTSLSTSEIALAILGAGIVLRLCWFAVAFLRLGRLR
HHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHSQPLTPPTAWSVEADIRVSEAISSPVTFGFLRPVVLLPANFSELDVQIQDAILCHEVL
HCCCCCCCCCCCCEEECCCHHHHHCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHH
HVRRRDWLFTLGEELVRSLFWFHPAIWWLLGEIGLAREQEVDRLVVELTKSREGYVDALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
AIAGAAPRLDLAPAPLFLRKRHLKQRVVSIMKEVRMSKTRSFSALAAGLGFLAAACWLVT
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATFPLAAAPQSVNDFPGVTVDTGGPVMHRTAVIYPDAARLHNIQGVVVVEASLDSSGNVT
HHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHCCCCEEEEEEECCCCCCCCC
DTRVLSGPPELRRAAQQAVLQWHFSMEGSSNTRQVKINFELPSGQRAPATVVTVNPPAMG
CCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCC
AVNDPEKIAAAEAKIRALRSQITDQTAALRSSQDEAARQQAAAKLSELQENVSNLQRNLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PASLAGKRLARINVMGLSDQVRDQLLSRLPVHTGDTLSADSYDLTSKAVREFDEHMFVSQ
CHHHHCCHHHEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
SANSQTGEVAFTIVQGGGSIASVSMTAPTTPATPGVKRITIGGNVQQTKLVSQARPVYPP
CCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCC
LAKQARISGVVHLQAVIAKDGNVMDLKVISGHPLLIPAALEAVKTWVYQTTLLNGEPVEV
CHHHHHHHHHEEEEEEEECCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHEECCCCCEEE
VTQIDVNFTLSEEGGN
EEEEEEEEEECCCCCC
>Mature Secondary Structure 
STHLIWDNLVAYSMQIGLLIGLAAFVPALLRLKVPHTKLAYWQILLATCLLLPAVRPWK
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHH
QAMLTVSRPVFSNIADLPPMQPMPPTSLSTSEIALAILGAGIVLRLCWFAVAFLRLGRLR
HHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHSQPLTPPTAWSVEADIRVSEAISSPVTFGFLRPVVLLPANFSELDVQIQDAILCHEVL
HCCCCCCCCCCCCEEECCCHHHHHCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHH
HVRRRDWLFTLGEELVRSLFWFHPAIWWLLGEIGLAREQEVDRLVVELTKSREGYVDALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
AIAGAAPRLDLAPAPLFLRKRHLKQRVVSIMKEVRMSKTRSFSALAAGLGFLAAACWLVT
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATFPLAAAPQSVNDFPGVTVDTGGPVMHRTAVIYPDAARLHNIQGVVVVEASLDSSGNVT
HHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHCCCCEEEEEEECCCCCCCCC
DTRVLSGPPELRRAAQQAVLQWHFSMEGSSNTRQVKINFELPSGQRAPATVVTVNPPAMG
CCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCC
AVNDPEKIAAAEAKIRALRSQITDQTAALRSSQDEAARQQAAAKLSELQENVSNLQRNLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PASLAGKRLARINVMGLSDQVRDQLLSRLPVHTGDTLSADSYDLTSKAVREFDEHMFVSQ
CHHHHCCHHHEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
SANSQTGEVAFTIVQGGGSIASVSMTAPTTPATPGVKRITIGGNVQQTKLVSQARPVYPP
CCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCC
LAKQARISGVVHLQAVIAKDGNVMDLKVISGHPLLIPAALEAVKTWVYQTTLLNGEPVEV
CHHHHHHHHHEEEEEEEECCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHEECCCCCEEE
VTQIDVNFTLSEEGGN
EEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]