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The map label for this gene is 116620043

Identifier: 116620043

GI number: 116620043

Start: 1143245

End: 1144777

Strand: Direct

Name: 116620043

Synonym: Acid_0915

Alternate gene names: NA

Gene position: 1143245-1144777 (Clockwise)

Preceding gene: 116620042

Following gene: 116620044

Centisome position: 11.47

GC content: 59.95

Gene sequence:

>1533_bases
ATGACCGAGGTGCCCATGTCGTTTACCAGACGCAGTCTTTTTGGCCTTGCAGCCGCTGCTCCCGCGTTGCTTTTGCCGCG
CCGGTCCCAGGCGCAGGAAAGTATCCCCGAAATTGCGAAAGGCCCGTTCGACGGCGCCGAATCGCTCAAAAAGTACCGGA
TTCCCGAATGGTTCCGGGATTACAAGTTCGGCATGTGGGCCCACTGGGGGCCGCAATCCGCCGCGGAGTTCGGCGATTGG
TACGCGCGCAATATGTACATGCAGGACAGCCCGCAGAACAAGTATCACGTCGAGAAATACGGGCATCCCTCGAAATTTGG
CTTCAAAGACGTCGCTCTCACCTGGCACGGCAAGGATTTCGACGCCGATTACCTCATTCAGCTCTACAAAAAAGCCGGCG
CCAAATATTTCATGTCGATGGGCGTCCACCACGACAACTTCGATCTCTGGAACTCCAAATATCAGCCGCGCTGGAATGCC
GTAGCCACCGGCCCCAAGAAGGATATCGTCGGCCTGTTCGCGTCCGCAGCGCGCAAGCACGGGCTCAAGTTCGCGGTCAG
CGAACATCTCTCGAACAGCTACAACTGGCTCGCCGTCTCTCACGGCGCCGATAAGACCGGCCCTCTCGCCGGGGTGCCTT
ACGATGGAACTGACCCGGCCTATGCCGATCTCTATCATCCCTTCCCCAAGGACAAGCCGATTCCCACGCAGGCCATGAGC
CGCGAGGCTCCGGATTCCTGGAAGCGCCTCTACTTCCTGCGCATCCAGGACCTGATCGACAAGTACAAGCCCGACTTGCT
GTACACCGATGGCGGCATCCCCTTCGGCGAGTGGGGCTACAAGCTGGTTTCACACTATTACAATCAGGTGCCCAACGGCC
TGTACACCAGCAAGACCAGGAAGGATTGCGAAGAGGGAACCTGCGCACTCGATATCGAGCGCGGCGTGGCGGGCGATATC
CTGCCCAATCCCTGGCAGACCGATACCTGTATCGGCGGCTGGCACTACAAGAAGGGCGCGAAATACAAGACCGGGAAGAA
CGTGGTGGATCTGCTGTGCGACATCGTCAGCCGCAATGGCAACCTGATGCTCAATGTCCCGCTACCCAATAGCGGCAAGC
CAGACGACGACGAACTCAAGACCGTCGAGGAGATCACCAAGTGGATGGCGGTCAACAGCGAGGGCATCTACAGCACGCGC
CCCTGGAAGATCGCCGGCAGCGCAGCACCGCCCGTTACGGGCAATACGGCCTTCAATGAACGCAACCGCAAAGAGCTGAC
CGCGGCCGATGTTCGCTATACCGTCAAGAACGGAACGCTGTACGCCTTCGTGATGGGATGGCCGGAGCGTGAAGCCGTGA
TTCCGACGCTTGCGCTCGGCGGCGCCAACCAGGTGGGCAAGGTTCGTGGCGTGACCCTGCTGGGCCACCGCGGCAGCCTG
AAATTCACCCAGGACGAGCAATCGCTGCGCGTTACGCTGCCACCCGAGAAACCCTGCGAACACGCCGTCTGCTTCAAAAT
CGTGGGCGCCTGA

Upstream 100 bases:

>100_bases
AAACTGGTCCGAAGAAGTTCTGTAGCCGCGGCAGGCGCGTCCGCCCGCGGCGGCCGGCGAGGGGATGCGCCAGTTCCCGA
TTATTGCGCTAAAGTAAACG

Downstream 100 bases:

>100_bases
TTCAACCGGGATACTGCGACAGGGTTCACTGCGATACCCTGAGAACGGTGCGTCCCGTCCTGTTTATTCTGATTGCTGCG
CTCGCCGCCTGTCGCACCGC

Product: glycoside hydrolase family alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycosyl Hydrolase; Glycoside Hydrolase Family; Glycoside Hydrolase Family Alpha-L-Fucosidase; Family; Fucosidase; Alpha-L-Fucosidase Superfamily; Alpha-L-Fucosidase Protein

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTEVPMSFTRRSLFGLAAAAPALLLPRRSQAQESIPEIAKGPFDGAESLKKYRIPEWFRDYKFGMWAHWGPQSAAEFGDW
YARNMYMQDSPQNKYHVEKYGHPSKFGFKDVALTWHGKDFDADYLIQLYKKAGAKYFMSMGVHHDNFDLWNSKYQPRWNA
VATGPKKDIVGLFASAARKHGLKFAVSEHLSNSYNWLAVSHGADKTGPLAGVPYDGTDPAYADLYHPFPKDKPIPTQAMS
REAPDSWKRLYFLRIQDLIDKYKPDLLYTDGGIPFGEWGYKLVSHYYNQVPNGLYTSKTRKDCEEGTCALDIERGVAGDI
LPNPWQTDTCIGGWHYKKGAKYKTGKNVVDLLCDIVSRNGNLMLNVPLPNSGKPDDDELKTVEEITKWMAVNSEGIYSTR
PWKIAGSAAPPVTGNTAFNERNRKELTAADVRYTVKNGTLYAFVMGWPEREAVIPTLALGGANQVGKVRGVTLLGHRGSL
KFTQDEQSLRVTLPPEKPCEHAVCFKIVGA

Sequences:

>Translated_510_residues
MTEVPMSFTRRSLFGLAAAAPALLLPRRSQAQESIPEIAKGPFDGAESLKKYRIPEWFRDYKFGMWAHWGPQSAAEFGDW
YARNMYMQDSPQNKYHVEKYGHPSKFGFKDVALTWHGKDFDADYLIQLYKKAGAKYFMSMGVHHDNFDLWNSKYQPRWNA
VATGPKKDIVGLFASAARKHGLKFAVSEHLSNSYNWLAVSHGADKTGPLAGVPYDGTDPAYADLYHPFPKDKPIPTQAMS
REAPDSWKRLYFLRIQDLIDKYKPDLLYTDGGIPFGEWGYKLVSHYYNQVPNGLYTSKTRKDCEEGTCALDIERGVAGDI
LPNPWQTDTCIGGWHYKKGAKYKTGKNVVDLLCDIVSRNGNLMLNVPLPNSGKPDDDELKTVEEITKWMAVNSEGIYSTR
PWKIAGSAAPPVTGNTAFNERNRKELTAADVRYTVKNGTLYAFVMGWPEREAVIPTLALGGANQVGKVRGVTLLGHRGSL
KFTQDEQSLRVTLPPEKPCEHAVCFKIVGA
>Mature_509_residues
TEVPMSFTRRSLFGLAAAAPALLLPRRSQAQESIPEIAKGPFDGAESLKKYRIPEWFRDYKFGMWAHWGPQSAAEFGDWY
ARNMYMQDSPQNKYHVEKYGHPSKFGFKDVALTWHGKDFDADYLIQLYKKAGAKYFMSMGVHHDNFDLWNSKYQPRWNAV
ATGPKKDIVGLFASAARKHGLKFAVSEHLSNSYNWLAVSHGADKTGPLAGVPYDGTDPAYADLYHPFPKDKPIPTQAMSR
EAPDSWKRLYFLRIQDLIDKYKPDLLYTDGGIPFGEWGYKLVSHYYNQVPNGLYTSKTRKDCEEGTCALDIERGVAGDIL
PNPWQTDTCIGGWHYKKGAKYKTGKNVVDLLCDIVSRNGNLMLNVPLPNSGKPDDDELKTVEEITKWMAVNSEGIYSTRP
WKIAGSAAPPVTGNTAFNERNRKELTAADVRYTVKNGTLYAFVMGWPEREAVIPTLALGGANQVGKVRGVTLLGHRGSLK
FTQDEQSLRVTLPPEKPCEHAVCFKIVGA

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40068512, Length=477, Percent_Identity=27.0440251572327, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI119360348, Length=482, Percent_Identity=23.8589211618257, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71997700, Length=378, Percent_Identity=24.0740740740741, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24662717, Length=500, Percent_Identity=23.6, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78706642, Length=500, Percent_Identity=23.6, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 57237; Mature: 57106

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVPMSFTRRSLFGLAAAAPALLLPRRSQAQESIPEIAKGPFDGAESLKKYRIPEWFRD
CCCCCHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHH
YKFGMWAHWGPQSAAEFGDWYARNMYMQDSPQNKYHVEKYGHPSKFGFKDVALTWHGKDF
CCCCCEECCCCCHHHHHHHHHHHCCEECCCCCCCEEHHHCCCCCCCCCEEEEEEECCCCC
DADYLIQLYKKAGAKYFMSMGVHHDNFDLWNSKYQPRWNAVATGPKKDIVGLFASAARKH
CHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLKFAVSEHLSNSYNWLAVSHGADKTGPLAGVPYDGTDPAYADLYHPFPKDKPIPTQAMS
CCEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHC
REAPDSWKRLYFLRIQDLIDKYKPDLLYTDGGIPFGEWGYKLVSHYYNQVPNGLYTSKTR
CCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
KDCEEGTCALDIERGVAGDILPNPWQTDTCIGGWHYKKGAKYKTGKNVVDLLCDIVSRNG
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEECCCEECCCCCCCCCCHHHHHHHHHHCCCC
NLMLNVPLPNSGKPDDDELKTVEEITKWMAVNSEGIYSTRPWKIAGSAAPPVTGNTAFNE
CEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
RNRKELTAADVRYTVKNGTLYAFVMGWPEREAVIPTLALGGANQVGKVRGVTLLGHRGSL
CCCHHEEHHHEEEEEECCEEEEEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCE
KFTQDEQSLRVTLPPEKPCEHAVCFKIVGA
EEECCCCCEEEECCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TEVPMSFTRRSLFGLAAAAPALLLPRRSQAQESIPEIAKGPFDGAESLKKYRIPEWFRD
CCCCHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHH
YKFGMWAHWGPQSAAEFGDWYARNMYMQDSPQNKYHVEKYGHPSKFGFKDVALTWHGKDF
CCCCCEECCCCCHHHHHHHHHHHCCEECCCCCCCEEHHHCCCCCCCCCEEEEEEECCCCC
DADYLIQLYKKAGAKYFMSMGVHHDNFDLWNSKYQPRWNAVATGPKKDIVGLFASAARKH
CHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLKFAVSEHLSNSYNWLAVSHGADKTGPLAGVPYDGTDPAYADLYHPFPKDKPIPTQAMS
CCEEEHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHC
REAPDSWKRLYFLRIQDLIDKYKPDLLYTDGGIPFGEWGYKLVSHYYNQVPNGLYTSKTR
CCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHH
KDCEEGTCALDIERGVAGDILPNPWQTDTCIGGWHYKKGAKYKTGKNVVDLLCDIVSRNG
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEECCCEECCCCCCCCCCHHHHHHHHHHCCCC
NLMLNVPLPNSGKPDDDELKTVEEITKWMAVNSEGIYSTRPWKIAGSAAPPVTGNTAFNE
CEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
RNRKELTAADVRYTVKNGTLYAFVMGWPEREAVIPTLALGGANQVGKVRGVTLLGHRGSL
CCCHHEEHHHEEEEEECCEEEEEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCE
KFTQDEQSLRVTLPPEKPCEHAVCFKIVGA
EEECCCCCEEEECCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA