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The map label for this gene is accC [H]

Identifier: 116619994

GI number: 116619994

Start: 1075779

End: 1079294

Strand: Reverse

Name: accC [H]

Synonym: Acid_0866

Alternate gene names: 116619994

Gene position: 1079294-1075779 (Counterclockwise)

Preceding gene: 116619995

Following gene: 116619993

Centisome position: 10.83

GC content: 65.1

Gene sequence:

>3516_bases
ATGTTCCGGAAGGTCCTGATCGCCAACCGCGGCGCGATCGCCTGCCGCATCATTCGCACGCTGCGCGCCATGGAGGTGGG
ATCGGTGGCGGTGTATTCCGCGGCCGACCGCCACTCGGTGCATGTCCGGCAAGCCGATGAAGCCATCGAGATCGGACCCG
CGCCGGCGTCGCAGAGCTACCTCTCGATCGACGCTTTGCTCAATGCCGCCGAGATGACCGGTGCGGAGGCAATTCATCCG
GGTTACGGATTCCTGAGCGAGAACGCGGATTTCGCCGAGGAGTGCACGCTGCGCGGCATCGCCTTCATCGGGCCTACGCC
GGCGCAGATGCGCGCTTTCGGGCTTAAGCATACGGCCCGCGAAATCGCAGCGAAGAATGGCGTTCCGCTCGCGCCCGGCA
GCGGACTGCTCGCATCCGTCGAAGAAGCGCTAATGTCGGTGGAGCGCATTGGATACCCGGTCATGCTTAAGAGCACCGCC
GGAGGAGGCGGCATTGGCATGCGCCTGTGCCGCGACGAGAGTGAACTGCGCGAGGGATATACCGCGGTGGAGCGTCTGGG
GCGAGCCAACTTCGGGGCAGCGGGACTCTATCTGGAAAAGTTCACTGCCAACGCGCGGCACATCGAGGTCCAGATCTTCG
GAGATGGCATGGGCGAAGTCATCGCTCTCGGCGAGCGCGATTGTTCGGCCCAGCGCCGCAATCAAAAAGTGATTGAAGAG
ACACCGGCGCCGGGGATTTCCCCCGGGGTGCGCGAGCGTCTGTTCGATGCCGCGCTGCGGCTGGGCCGCGCCGTGCGCTA
TCGCTCGGCCGGCACGGTGGAGTTTATCTACGACAACGACACCGCGCAGTTCCACTTTCTGGAAGTCAATACGCGGCTGC
AGGTGGAGCACGGCGTCACCGAGGAAGTGACGGGAATCGATCTGGTGGAGTGGATGGTCCGGCTGGCGGCGCACGAGTTG
CCGCCACTGGAGAGACTTGCGGTTCGACCGTGCGGCGCTTCCATCCAGATTCGCATTTACGCAGAAGACCCGGCGAAGGA
GTTTCAGCCCGGCGCCGGACGGCTCACGCACGTTGCGTGGCCGGCCGGGGCCCGCGTGGAAAGCTGGGTGGAAGCCGGAA
GCGAGGTGACGCCGTATTACGACCCAATGCTTGCCAAGATTATCGTGCGCGGCGGGGATCGGACCGAGGCGCTCTCGAGG
CTTCGCGCTGCGCTGGAGGCAACGCGCCTCGCCGGAATCGAGACGAATCTCGAGTATCTACGCCAGGTCGCCGCGGGCGA
GGTATTCGCCGCCGGCGGTATCACGACCGCTTCACTCGGCGCCTTCGATTACCGGCGCAGCGCAATCGATGTGGTCGATG
GCGGCGTGCAGACTACTGTGCAGGATTATCCCGGGCGCCTCGGCTACTGGCACGTGGGAGTGCCGCCCTCGGGTCCGATG
GATCCGCTGGCGTTCCGGCTCGCTAATCGCGCGACCGGCAATCCCGAGACCGCCGCAGGCCTGGAGATCGCCGTGGTCGG
GCCGACGCTTCGCTTTGCCTGCGACACGGTGATTGCGGTCACGGGCGCCAACTTCGATGCGCGGCTCGACGGCGTTCCGA
TTCCACGGTGGGCGGCCGTGTCGGTCAAGGGCGGCTCGTTGTTAACGATGACTACGGCGCAATCCGCGGGGGCGCGCGCT
TATCTCGCGATCGCGGGCGGCATCGATGTCCCTGAGTATCTGGGGAGCGGCAGCACTTTCATCCTCGGGAAGTTTGGCGG
CCACGCGGGCCGGTCGCTTCGCGCCGGGGACGTGCTCCACCTCGGAGCGGCCGCGGGTGATGCGCGCAGCATTTCGGCGC
CGCCCGAGTACACCAACGAGTGGGAGATCGGAGTACTTTACGGGCCACACGGCGCGCCCGATTTCTTCACGGCCGAAGAC
ATCGAGATGTTCTTCTCCACGGCGTGGAAAGTGCATCACAATTCCGACCGCACCGGCACGCGGCTCATAGGACCGAAGCC
GAAATGGGCGCGGCCCGACGGCGGCGAAGCGGGGCTGCACCCTTCCAATATCCACGACAATGCGTACGCGATCGGCACAG
TGGATTTCACGGGCGACATGCCGGTGATTCTGGGCCCCGACGGTCCGAGTCTTGGTGGGTTCGTGTGCCCCGCCACGGTG
GTCCACGCGGAGCTTTGGAAGGTCGGTCAACTCCGGCCGGGAGATTCCGTGCGGTTCCGTGCGCTGACGCATGAGCAGGC
CGTGCGGATGGAGACTTCCCTGCCCCAGCCACCGGTGGCGCCGGTCGATCCCATCCTGCACTCCGCGCCGGGGGTGGTGG
TCCGCGCGGATGGCGACCGTTACCTGCTCGTCGAATACGGGCACAACGTGCTCGACCTCAATCTGCGCTTCCGTGTACAC
GCGCTGGAAGATCAGGTACGCGCGCTTGGACTGCGCGGCATCATCGACATCACGCCCGGTGTCCGTTCCTTACATATCCA
TTACGACACTGGCAGTCTTTCCCGCGAGGCACTGCTCGAAGCTCTGGATGCGTGCGAGCGCCAAATCCCGGAGCTCGACA
ACCTGGTCGCGCCGTCGCGCACAGTGCACCTTCCGCTCTCCTGGGATGACCCGGCAACGCAGTTGGCGATCCGCAAGTAC
ATGCAGGGCGTTCGCCCCGATGCGCCGTGGTGCCCGAGCAACATCGAATTCATACGTCGGATCAACGGGCTGGACTCCAT
CGAGGATGTGCGCGAGGTCGTGTTTGCCGCCAACTACCTGGTGCTCGGGCTCGGCGATGTCTATCTGGGGGCGCCGGTGG
CCACTCCGGTGGATCCGCGGCATCGACTGGTGACCACCAAGTACAATCCCGCGCGCACGTGGACCCCGGAGAATGCGGTC
GGCATTGGCGGCGCGTATCTGTGCGTTTACGGCATGGAGGGTCCAGGCGGATATCAATTCGTGGGCCGCACGGTGCAGAT
GTGGAATACCTTCCGCGGCTCGCCACCCTGGCTGCTTCGCTGTTTCGACCAGATCCGCTTCTATCCGGTCAGCGCAGCGG
AACTGCTGGAGATGCGCGAGGCCTTCCCTCATGGCGGCTGTCCGCTGAAGATCGAGGACGGCGAGTTTCGCCTGCGCGAC
TATCATGCGTTTCAACGATCGATCGAGCGCGAAGCTGCGGCGGCCAAGTCGCGGCAGCAAGCCGCGTTCGACGCGGAGCG
GGAACGCTGGACACTAGCCGGCGCAGATCGCTTCGTGGCGGCAGACGATTCCGGTTCCGGCGGCGCTCTGCTGGAGGACG
TGTTGCCCGATGGATGCCGGCCGGTGTGTTCGCCGGTCGCGGCCAGCGTGTGGAACGTTTCCGTGGAGACGGGGCAGCGA
GTGGAAGCGGGCCAAAAGCTCCTGGTTTTGGAGGCGATGAAAATGGAAATCGCGGTCGCCGCGCCTAGCGCAGGGGTTAT
CGAAATGGTGAATTGCATACCCGGAGCGCTGGTCTCGGCGGGCCAGCGATTGGTGACTTTAAGGCGGGAGATATGA

Upstream 100 bases:

>100_bases
TGCTGGCTATGATCAGCAACTGCCCTCAACTCAACAATCCCTGCAACGCGTATGACCCGACTCCAGTGCAGGTGCTGATC
TGGAACGGGCAGGGCGACTG

Downstream 100 bases:

>100_bases
CGATGAAGACCGAGATTCGTCTGGACCTCGCGTCCCTGCGCGAGTTGTACAAGTCCGGCAGAGCCACGCCTTCCGACGTA
ATCAGCGCGATTTACGATCG

Product: urea amidolyase-like protein

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A; ACC [H]

Number of amino acids: Translated: 1171; Mature: 1171

Protein sequence:

>1171_residues
MFRKVLIANRGAIACRIIRTLRAMEVGSVAVYSAADRHSVHVRQADEAIEIGPAPASQSYLSIDALLNAAEMTGAEAIHP
GYGFLSENADFAEECTLRGIAFIGPTPAQMRAFGLKHTAREIAAKNGVPLAPGSGLLASVEEALMSVERIGYPVMLKSTA
GGGGIGMRLCRDESELREGYTAVERLGRANFGAAGLYLEKFTANARHIEVQIFGDGMGEVIALGERDCSAQRRNQKVIEE
TPAPGISPGVRERLFDAALRLGRAVRYRSAGTVEFIYDNDTAQFHFLEVNTRLQVEHGVTEEVTGIDLVEWMVRLAAHEL
PPLERLAVRPCGASIQIRIYAEDPAKEFQPGAGRLTHVAWPAGARVESWVEAGSEVTPYYDPMLAKIIVRGGDRTEALSR
LRAALEATRLAGIETNLEYLRQVAAGEVFAAGGITTASLGAFDYRRSAIDVVDGGVQTTVQDYPGRLGYWHVGVPPSGPM
DPLAFRLANRATGNPETAAGLEIAVVGPTLRFACDTVIAVTGANFDARLDGVPIPRWAAVSVKGGSLLTMTTAQSAGARA
YLAIAGGIDVPEYLGSGSTFILGKFGGHAGRSLRAGDVLHLGAAAGDARSISAPPEYTNEWEIGVLYGPHGAPDFFTAED
IEMFFSTAWKVHHNSDRTGTRLIGPKPKWARPDGGEAGLHPSNIHDNAYAIGTVDFTGDMPVILGPDGPSLGGFVCPATV
VHAELWKVGQLRPGDSVRFRALTHEQAVRMETSLPQPPVAPVDPILHSAPGVVVRADGDRYLLVEYGHNVLDLNLRFRVH
ALEDQVRALGLRGIIDITPGVRSLHIHYDTGSLSREALLEALDACERQIPELDNLVAPSRTVHLPLSWDDPATQLAIRKY
MQGVRPDAPWCPSNIEFIRRINGLDSIEDVREVVFAANYLVLGLGDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAV
GIGGAYLCVYGMEGPGGYQFVGRTVQMWNTFRGSPPWLLRCFDQIRFYPVSAAELLEMREAFPHGGCPLKIEDGEFRLRD
YHAFQRSIEREAAAAKSRQQAAFDAERERWTLAGADRFVAADDSGSGGALLEDVLPDGCRPVCSPVAASVWNVSVETGQR
VEAGQKLLVLEAMKMEIAVAAPSAGVIEMVNCIPGALVSAGQRLVTLRREI

Sequences:

>Translated_1171_residues
MFRKVLIANRGAIACRIIRTLRAMEVGSVAVYSAADRHSVHVRQADEAIEIGPAPASQSYLSIDALLNAAEMTGAEAIHP
GYGFLSENADFAEECTLRGIAFIGPTPAQMRAFGLKHTAREIAAKNGVPLAPGSGLLASVEEALMSVERIGYPVMLKSTA
GGGGIGMRLCRDESELREGYTAVERLGRANFGAAGLYLEKFTANARHIEVQIFGDGMGEVIALGERDCSAQRRNQKVIEE
TPAPGISPGVRERLFDAALRLGRAVRYRSAGTVEFIYDNDTAQFHFLEVNTRLQVEHGVTEEVTGIDLVEWMVRLAAHEL
PPLERLAVRPCGASIQIRIYAEDPAKEFQPGAGRLTHVAWPAGARVESWVEAGSEVTPYYDPMLAKIIVRGGDRTEALSR
LRAALEATRLAGIETNLEYLRQVAAGEVFAAGGITTASLGAFDYRRSAIDVVDGGVQTTVQDYPGRLGYWHVGVPPSGPM
DPLAFRLANRATGNPETAAGLEIAVVGPTLRFACDTVIAVTGANFDARLDGVPIPRWAAVSVKGGSLLTMTTAQSAGARA
YLAIAGGIDVPEYLGSGSTFILGKFGGHAGRSLRAGDVLHLGAAAGDARSISAPPEYTNEWEIGVLYGPHGAPDFFTAED
IEMFFSTAWKVHHNSDRTGTRLIGPKPKWARPDGGEAGLHPSNIHDNAYAIGTVDFTGDMPVILGPDGPSLGGFVCPATV
VHAELWKVGQLRPGDSVRFRALTHEQAVRMETSLPQPPVAPVDPILHSAPGVVVRADGDRYLLVEYGHNVLDLNLRFRVH
ALEDQVRALGLRGIIDITPGVRSLHIHYDTGSLSREALLEALDACERQIPELDNLVAPSRTVHLPLSWDDPATQLAIRKY
MQGVRPDAPWCPSNIEFIRRINGLDSIEDVREVVFAANYLVLGLGDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAV
GIGGAYLCVYGMEGPGGYQFVGRTVQMWNTFRGSPPWLLRCFDQIRFYPVSAAELLEMREAFPHGGCPLKIEDGEFRLRD
YHAFQRSIEREAAAAKSRQQAAFDAERERWTLAGADRFVAADDSGSGGALLEDVLPDGCRPVCSPVAASVWNVSVETGQR
VEAGQKLLVLEAMKMEIAVAAPSAGVIEMVNCIPGALVSAGQRLVTLRREI
>Mature_1171_residues
MFRKVLIANRGAIACRIIRTLRAMEVGSVAVYSAADRHSVHVRQADEAIEIGPAPASQSYLSIDALLNAAEMTGAEAIHP
GYGFLSENADFAEECTLRGIAFIGPTPAQMRAFGLKHTAREIAAKNGVPLAPGSGLLASVEEALMSVERIGYPVMLKSTA
GGGGIGMRLCRDESELREGYTAVERLGRANFGAAGLYLEKFTANARHIEVQIFGDGMGEVIALGERDCSAQRRNQKVIEE
TPAPGISPGVRERLFDAALRLGRAVRYRSAGTVEFIYDNDTAQFHFLEVNTRLQVEHGVTEEVTGIDLVEWMVRLAAHEL
PPLERLAVRPCGASIQIRIYAEDPAKEFQPGAGRLTHVAWPAGARVESWVEAGSEVTPYYDPMLAKIIVRGGDRTEALSR
LRAALEATRLAGIETNLEYLRQVAAGEVFAAGGITTASLGAFDYRRSAIDVVDGGVQTTVQDYPGRLGYWHVGVPPSGPM
DPLAFRLANRATGNPETAAGLEIAVVGPTLRFACDTVIAVTGANFDARLDGVPIPRWAAVSVKGGSLLTMTTAQSAGARA
YLAIAGGIDVPEYLGSGSTFILGKFGGHAGRSLRAGDVLHLGAAAGDARSISAPPEYTNEWEIGVLYGPHGAPDFFTAED
IEMFFSTAWKVHHNSDRTGTRLIGPKPKWARPDGGEAGLHPSNIHDNAYAIGTVDFTGDMPVILGPDGPSLGGFVCPATV
VHAELWKVGQLRPGDSVRFRALTHEQAVRMETSLPQPPVAPVDPILHSAPGVVVRADGDRYLLVEYGHNVLDLNLRFRVH
ALEDQVRALGLRGIIDITPGVRSLHIHYDTGSLSREALLEALDACERQIPELDNLVAPSRTVHLPLSWDDPATQLAIRKY
MQGVRPDAPWCPSNIEFIRRINGLDSIEDVREVVFAANYLVLGLGDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAV
GIGGAYLCVYGMEGPGGYQFVGRTVQMWNTFRGSPPWLLRCFDQIRFYPVSAAELLEMREAFPHGGCPLKIEDGEFRLRD
YHAFQRSIEREAAAAKSRQQAAFDAERERWTLAGADRFVAADDSGSGGALLEDVLPDGCRPVCSPVAASVWNVSVETGQR
VEAGQKLLVLEAMKMEIAVAAPSAGVIEMVNCIPGALVSAGQRLVTLRREI

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=437, Percent_Identity=48.9702517162471, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI189095269, Length=444, Percent_Identity=45.945945945946, Blast_Score=382, Evalue=1e-105,
Organism=Homo sapiens, GI65506442, Length=444, Percent_Identity=45.945945945946, Blast_Score=382, Evalue=1e-105,
Organism=Homo sapiens, GI295821183, Length=444, Percent_Identity=45.945945945946, Blast_Score=382, Evalue=1e-105,
Organism=Homo sapiens, GI106049528, Length=443, Percent_Identity=41.7607223476298, Blast_Score=323, Evalue=8e-88,
Organism=Homo sapiens, GI106049295, Length=443, Percent_Identity=41.7607223476298, Blast_Score=323, Evalue=8e-88,
Organism=Homo sapiens, GI106049292, Length=443, Percent_Identity=41.7607223476298, Blast_Score=323, Evalue=8e-88,
Organism=Homo sapiens, GI38679960, Length=502, Percent_Identity=29.8804780876494, Blast_Score=207, Evalue=5e-53,
Organism=Homo sapiens, GI38679977, Length=502, Percent_Identity=29.8804780876494, Blast_Score=207, Evalue=5e-53,
Organism=Homo sapiens, GI38679967, Length=502, Percent_Identity=29.8804780876494, Blast_Score=207, Evalue=5e-53,
Organism=Homo sapiens, GI38679974, Length=502, Percent_Identity=29.8804780876494, Blast_Score=207, Evalue=5e-53,
Organism=Homo sapiens, GI38679971, Length=502, Percent_Identity=29.8804780876494, Blast_Score=207, Evalue=7e-53,
Organism=Homo sapiens, GI134142062, Length=514, Percent_Identity=30.1556420233463, Blast_Score=204, Evalue=4e-52,
Organism=Escherichia coli, GI1789654, Length=443, Percent_Identity=44.0180586907449, Blast_Score=344, Evalue=2e-95,
Organism=Escherichia coli, GI1786930, Length=304, Percent_Identity=31.9078947368421, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71987519, Length=437, Percent_Identity=46.6819221967963, Blast_Score=384, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17567343, Length=443, Percent_Identity=44.920993227991, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17562816, Length=498, Percent_Identity=39.7590361445783, Blast_Score=325, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI133931226, Length=484, Percent_Identity=29.5454545454545, Blast_Score=202, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI71997168, Length=450, Percent_Identity=29.3333333333333, Blast_Score=184, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71997163, Length=450, Percent_Identity=29.3333333333333, Blast_Score=183, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6319685, Length=1200, Percent_Identity=45.9166666666667, Blast_Score=1098, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=441, Percent_Identity=40.3628117913832, Blast_Score=289, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6319695, Length=441, Percent_Identity=39.4557823129252, Blast_Score=285, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6323863, Length=453, Percent_Identity=31.1258278145695, Blast_Score=214, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6324343, Length=506, Percent_Identity=30.0395256916996, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24651757, Length=437, Percent_Identity=44.8512585812357, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24651759, Length=401, Percent_Identity=43.640897755611, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24652212, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652210, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652214, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI19921944, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652216, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI281363050, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652224, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652222, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652220, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24652218, Length=443, Percent_Identity=42.4379232505643, Blast_Score=323, Evalue=4e-88,
Organism=Drosophila melanogaster, GI161076409, Length=503, Percent_Identity=29.8210735586481, Blast_Score=194, Evalue=4e-49,
Organism=Drosophila melanogaster, GI161076407, Length=503, Percent_Identity=29.8210735586481, Blast_Score=194, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24586460, Length=503, Percent_Identity=29.8210735586481, Blast_Score=194, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24586458, Length=503, Percent_Identity=29.8210735586481, Blast_Score=194, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 126280; Mature: 126280

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKVLIANRGAIACRIIRTLRAMEVGSVAVYSAADRHSVHVRQADEAIEIGPAPASQSY
CCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCEEEECCCCCCCCC
LSIDALLNAAEMTGAEAIHPGYGFLSENADFAEECTLRGIAFIGPTPAQMRAFGLKHTAR
EEHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHCEEEEECCCHHHHHHHHHHHHHH
EIAAKNGVPLAPGSGLLASVEEALMSVERIGYPVMLKSTAGGGGIGMRLCRDESELREGY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHH
TAVERLGRANFGAAGLYLEKFTANARHIEVQIFGDGMGEVIALGERDCSAQRRNQKVIEE
HHHHHHCCCCCCHHHEEEEEECCCCEEEEEEEECCCCCCEEEECCCCCHHHHHCCHHHHH
TPAPGISPGVRERLFDAALRLGRAVRYRSAGTVEFIYDNDTAQFHFLEVNTRLQVEHGVT
CCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCEEEEEEECCEEEECCCCC
EEVTGIDLVEWMVRLAAHELPPLERLAVRPCGASIQIRIYAEDPAKEFQPGAGRLTHVAW
HHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEEECCCHHHCCCCCCCEEEEEC
PAGARVESWVEAGSEVTPYYDPMLAKIIVRGGDRTEALSRLRAALEATRLAGIETNLEYL
CCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RQVAAGEVFAAGGITTASLGAFDYRRSAIDVVDGGVQTTVQDYPGRLGYWHVGVPPSGPM
HHHHCCCEEECCCCCCHHCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCC
DPLAFRLANRATGNPETAAGLEIAVVGPTLRFACDTVIAVTGANFDARLDGVPIPRWAAV
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCEEEEEECCCCCCEECCCCCCCEEEE
SVKGGSLLTMTTAQSAGARAYLAIAGGIDVPEYLGSGSTFILGKFGGHAGRSLRAGDVLH
EECCCCEEEEEECCCCCCEEEEEEECCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
LGAAAGDARSISAPPEYTNEWEIGVLYGPHGAPDFFTAEDIEMFFSTAWKVHHNSDRTGT
EECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCC
RLIGPKPKWARPDGGEAGLHPSNIHDNAYAIGTVDFTGDMPVILGPDGPSLGGFVCPATV
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCEECHHHH
VHAELWKVGQLRPGDSVRFRALTHEQAVRMETSLPQPPVAPVDPILHSAPGVVVRADGDR
HHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEECCCE
YLLVEYGHNVLDLNLRFRVHALEDQVRALGLRGIIDITPGVRSLHIHYDTGSLSREALLE
EEEEECCCCEEEEEEEEEEEHHHHHHHHHCCCCEEECCCCCEEEEEEECCCCCCHHHHHH
ALDACERQIPELDNLVAPSRTVHLPLSWDDPATQLAIRKYMQGVRPDAPWCPSNIEFIRR
HHHHHHHHCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
INGLDSIEDVREVVFAANYLVLGLGDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAV
HCCCCHHHHHHHHHHHHCEEEEECCCHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
GIGGAYLCVYGMEGPGGYQFVGRTVQMWNTFRGSPPWLLRCFDQIRFYPVSAAELLEMRE
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHH
AFPHGGCPLKIEDGEFRLRDYHAFQRSIEREAAAAKSRQQAAFDAERERWTLAGADRFVA
HCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEE
ADDSGSGGALLEDVLPDGCRPVCSPVAASVWNVSVETGQRVEAGQKLLVLEAMKMEIAVA
ECCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEEECCCCCCHHCCCEEEEEEEEEEEEEEE
APSAGVIEMVNCIPGALVSAGQRLVTLRREI
CCCCCHHHHHHHCCHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MFRKVLIANRGAIACRIIRTLRAMEVGSVAVYSAADRHSVHVRQADEAIEIGPAPASQSY
CCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCEEEECCCCCCCCC
LSIDALLNAAEMTGAEAIHPGYGFLSENADFAEECTLRGIAFIGPTPAQMRAFGLKHTAR
EEHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHCEEEEECCCHHHHHHHHHHHHHH
EIAAKNGVPLAPGSGLLASVEEALMSVERIGYPVMLKSTAGGGGIGMRLCRDESELREGY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHHHHHH
TAVERLGRANFGAAGLYLEKFTANARHIEVQIFGDGMGEVIALGERDCSAQRRNQKVIEE
HHHHHHCCCCCCHHHEEEEEECCCCEEEEEEEECCCCCCEEEECCCCCHHHHHCCHHHHH
TPAPGISPGVRERLFDAALRLGRAVRYRSAGTVEFIYDNDTAQFHFLEVNTRLQVEHGVT
CCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCEEEEEEECCEEEECCCCC
EEVTGIDLVEWMVRLAAHELPPLERLAVRPCGASIQIRIYAEDPAKEFQPGAGRLTHVAW
HHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEEECCCHHHCCCCCCCEEEEEC
PAGARVESWVEAGSEVTPYYDPMLAKIIVRGGDRTEALSRLRAALEATRLAGIETNLEYL
CCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RQVAAGEVFAAGGITTASLGAFDYRRSAIDVVDGGVQTTVQDYPGRLGYWHVGVPPSGPM
HHHHCCCEEECCCCCCHHCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCC
DPLAFRLANRATGNPETAAGLEIAVVGPTLRFACDTVIAVTGANFDARLDGVPIPRWAAV
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCEEEEEECCCCCCEECCCCCCCEEEE
SVKGGSLLTMTTAQSAGARAYLAIAGGIDVPEYLGSGSTFILGKFGGHAGRSLRAGDVLH
EECCCCEEEEEECCCCCCEEEEEEECCCCCHHHHCCCCEEEEECCCCCCCCCCCCCCEEE
LGAAAGDARSISAPPEYTNEWEIGVLYGPHGAPDFFTAEDIEMFFSTAWKVHHNSDRTGT
EECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCC
RLIGPKPKWARPDGGEAGLHPSNIHDNAYAIGTVDFTGDMPVILGPDGPSLGGFVCPATV
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCEECHHHH
VHAELWKVGQLRPGDSVRFRALTHEQAVRMETSLPQPPVAPVDPILHSAPGVVVRADGDR
HHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEECCCE
YLLVEYGHNVLDLNLRFRVHALEDQVRALGLRGIIDITPGVRSLHIHYDTGSLSREALLE
EEEEECCCCEEEEEEEEEEEHHHHHHHHHCCCCEEECCCCCEEEEEEECCCCCCHHHHHH
ALDACERQIPELDNLVAPSRTVHLPLSWDDPATQLAIRKYMQGVRPDAPWCPSNIEFIRR
HHHHHHHHCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
INGLDSIEDVREVVFAANYLVLGLGDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAV
HCCCCHHHHHHHHHHHHCEEEEECCCHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCC
GIGGAYLCVYGMEGPGGYQFVGRTVQMWNTFRGSPPWLLRCFDQIRFYPVSAAELLEMRE
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEECCCHHHHHHHHH
AFPHGGCPLKIEDGEFRLRDYHAFQRSIEREAAAAKSRQQAAFDAERERWTLAGADRFVA
HCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEE
ADDSGSGGALLEDVLPDGCRPVCSPVAASVWNVSVETGQRVEAGQKLLVLEAMKMEIAVA
ECCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEEECCCCCCHHCCCEEEEEEEEEEEEEEE
APSAGVIEMVNCIPGALVSAGQRLVTLRREI
CCCCCHHHHHHHCCHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]