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The map label for this gene is nrdR

Identifier: 116619923

GI number: 116619923

Start: 991977

End: 992438

Strand: Direct

Name: nrdR

Synonym: Acid_0795

Alternate gene names: 116619923

Gene position: 991977-992438 (Clockwise)

Preceding gene: 116619922

Following gene: 116619924

Centisome position: 9.95

GC content: 53.03

Gene sequence:

>462_bases
TTGAAGTGTCCATTCTGCAACCATCTACATGACAAGGTAGTAGATTCACGGGAAAGCAAGGAGGGCGATGCCATTCGCCG
CCGTCGCGAGTGCCTGGAATGTACTCGGCGCTATACCACCTATGAGCGGATCGATGAAGTTCCCTACATGGTGGTCAAGA
AAGATGGGCGCCGCGAGAAGTTTGACCGGCAGAAGGTGTTGGGCGGCCTGCTCAAGGCCTGCGAAAAGCGTCCGGTGAGC
ATGGCCAAGCTCTCCGAACTGGTCAACCGGGTAGAGTACAAGGTGAGCGATTCACCAGACCGTGAGATATCTACTATAGA
TATAGGAGAATATCTGATGGAGAACCTGAGGGAGCTGGACAAGATCGCCTATGTCCGTTTCGCCTCGGTATACAGAGATT
TCCAGGATGAGCAGGCGTTTTTCAACGAGCTGAAGCACCTGATGCGCCAGAAGATGTCCTAA

Upstream 100 bases:

>100_bases
TTCTTACATTCGTAGCAATTGTACCGTTGGGCCTGATCGTAGCCCTTAAAGAGGGGCTCGACTGGCACAGCCTGCGCCGG
ATTGGGCAGGAGGAATCGCT

Downstream 100 bases:

>100_bases
AAGGGGCTAGGGGATATACCCCCTTTGTGCTGGCTGCTACCCGGTTCAGTGACTCTTTTGATTTTCTCTGTAACCTAAAC
GATTGTAAGACATCTTTAAA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MKCPFCNHLHDKVVDSRESKEGDAIRRRRECLECTRRYTTYERIDEVPYMVVKKDGRREKFDRQKVLGGLLKACEKRPVS
MAKLSELVNRVEYKVSDSPDREISTIDIGEYLMENLRELDKIAYVRFASVYRDFQDEQAFFNELKHLMRQKMS

Sequences:

>Translated_153_residues
MKCPFCNHLHDKVVDSRESKEGDAIRRRRECLECTRRYTTYERIDEVPYMVVKKDGRREKFDRQKVLGGLLKACEKRPVS
MAKLSELVNRVEYKVSDSPDREISTIDIGEYLMENLRELDKIAYVRFASVYRDFQDEQAFFNELKHLMRQKMS
>Mature_153_residues
MKCPFCNHLHDKVVDSRESKEGDAIRRRRECLECTRRYTTYERIDEVPYMVVKKDGRREKFDRQKVLGGLLKACEKRPVS
MAKLSELVNRVEYKVSDSPDREISTIDIGEYLMENLRELDKIAYVRFASVYRDFQDEQAFFNELKHLMRQKMS

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.2176870748299, Blast_Score=132, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_SOLUE (Q02AX2)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_822079.1
- STRING:   Q02AX2
- GeneID:   4431073
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0795
- NMPDR:   fig|234267.9.peg.746
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q02AX2
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18294; Mature: 18294

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCNHLHDKVVDSRESKEGDAIRRRRECLECTRRYTTYERIDEVPYMVVKKDGRREK
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHH
FDRQKVLGGLLKACEKRPVSMAKLSELVNRVEYKVSDSPDREISTIDIGEYLMENLRELD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KIAYVRFASVYRDFQDEQAFFNELKHLMRQKMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCNHLHDKVVDSRESKEGDAIRRRRECLECTRRYTTYERIDEVPYMVVKKDGRREK
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHH
FDRQKVLGGLLKACEKRPVSMAKLSELVNRVEYKVSDSPDREISTIDIGEYLMENLRELD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
KIAYVRFASVYRDFQDEQAFFNELKHLMRQKMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA