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The map label for this gene is algU [H]

Identifier: 116619828

GI number: 116619828

Start: 871997

End: 872575

Strand: Direct

Name: algU [H]

Synonym: Acid_0698

Alternate gene names: 116619828

Gene position: 871997-872575 (Clockwise)

Preceding gene: 116619827

Following gene: 116619829

Centisome position: 8.75

GC content: 62.69

Gene sequence:

>579_bases
ATGGAACGAGGGCGTTCGTCGAGGCTGGCCAGGGTAGACTGCGATTCAGGCGCCAGTGAGCGGGAGGACTTCGATTCGCT
GGTGCGCCTGCACCGGCCGCGGATCTTCCGGTTCATTCTGGCTTCGTTGCGCGACCGGGAGACGGCGGAGAACCTGACTC
AGGACTGTTTTATCCGGGCGTACCAGGCGCGGGAACAGTTTCGCGGCGCCTCCAGCATCGCAACCTGGTTCATGCAAATT
GCGGCGAACCTGGTGCGCAATCACGAATCCAGCAGCCGCCTGAAGTTCTGGAGGCGGTCGCTGCACTCCGATACGGATGT
TGCCGATCTGGGGAACTCCCTGGCGGACCGGCAGCAGTCTCCGGAAGCGGAAGTACTGATCCGGGAGCAGGTAGAGGCAA
TCTGGACGGCCGCGGCGCATCTGCCCGCGCGGCAGCGGACCGTCTTCCTGCTCCGGTTTGTGGAAGACATGGACCTTCTG
GAGATCGCCGAAGTAACGGGGATGAAAGAAGGCACGGTAAAGGCACACCTCTTTCGGGCGCTGCATTCGGTGCGCGCCAG
GCTGGAGGCAACCAAATGA

Upstream 100 bases:

>100_bases
TCGCATTATGGGCGGGACGGCGGCGGAAGCCTACGGGTTGTGAGCCTCTCCTTACATTGCGTGTAAACCCAAACCGCCCG
GAATCGGTCTATACCTTCGA

Downstream 100 bases:

>100_bases
GCAAACATTTTTCTGAACATTTTACTGAGCACTTTTCTGAACAAGGAGTCCTTATGTACCTCATCGGCGACAGCACTGTG
GAAGAACGTAAACACGCGGA

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MERGRSSRLARVDCDSGASEREDFDSLVRLHRPRIFRFILASLRDRETAENLTQDCFIRAYQAREQFRGASSIATWFMQI
AANLVRNHESSSRLKFWRRSLHSDTDVADLGNSLADRQQSPEAEVLIREQVEAIWTAAAHLPARQRTVFLLRFVEDMDLL
EIAEVTGMKEGTVKAHLFRALHSVRARLEATK

Sequences:

>Translated_192_residues
MERGRSSRLARVDCDSGASEREDFDSLVRLHRPRIFRFILASLRDRETAENLTQDCFIRAYQAREQFRGASSIATWFMQI
AANLVRNHESSSRLKFWRRSLHSDTDVADLGNSLADRQQSPEAEVLIREQVEAIWTAAAHLPARQRTVFLLRFVEDMDLL
EIAEVTGMKEGTVKAHLFRALHSVRARLEATK
>Mature_192_residues
MERGRSSRLARVDCDSGASEREDFDSLVRLHRPRIFRFILASLRDRETAENLTQDCFIRAYQAREQFRGASSIATWFMQI
AANLVRNHESSSRLKFWRRSLHSDTDVADLGNSLADRQQSPEAEVLIREQVEAIWTAAAHLPARQRTVFLLRFVEDMDLL
EIAEVTGMKEGTVKAHLFRALHSVRARLEATK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=145, Percent_Identity=28.2758620689655, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22098; Mature: 22098

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERGRSSRLARVDCDSGASEREDFDSLVRLHRPRIFRFILASLRDRETAENLTQDCFIRA
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQAREQFRGASSIATWFMQIAANLVRNHESSSRLKFWRRSLHSDTDVADLGNSLADRQQS
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PEAEVLIREQVEAIWTAAAHLPARQRTVFLLRFVEDMDLLEIAEVTGMKEGTVKAHLFRA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LHSVRARLEATK
HHHHHHHHHCCC
>Mature Secondary Structure
MERGRSSRLARVDCDSGASEREDFDSLVRLHRPRIFRFILASLRDRETAENLTQDCFIRA
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YQAREQFRGASSIATWFMQIAANLVRNHESSSRLKFWRRSLHSDTDVADLGNSLADRQQS
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PEAEVLIREQVEAIWTAAAHLPARQRTVFLLRFVEDMDLLEIAEVTGMKEGTVKAHLFRA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LHSVRARLEATK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]