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The map label for this gene is exuT [H]

Identifier: 116619803

GI number: 116619803

Start: 843872

End: 845122

Strand: Direct

Name: exuT [H]

Synonym: Acid_0673

Alternate gene names: 116619803

Gene position: 843872-845122 (Clockwise)

Preceding gene: 116619802

Following gene: 116619804

Centisome position: 8.47

GC content: 63.95

Gene sequence:

>1251_bases
ATGTTCAGCGCCTCGGAAGCATCGACGAAAGCCGCACCGGGCAGGCTGCCGGGGGCGCTGTGGGGAGTACTGGCTCTATT
GGTGATTTCGGTCGCGATCAATTACATCGATCGCGGCAACCTCTCCATCGCGGCCCCGCTGCTGAAAGAGGAACTGAGGA
TTTCTCCGGCGCAGCTGGGCCTGCTGCTCTCCTCGTTCTTCTGGACCTACTCGACATTTCAGATCGTCTCCGGTTGGCTG
GTGGACCGGTTCGACGTGAACCGGGTCATCGCCGCGGGCTTCCTGCTCTGGTCGGCCGCGACCGCTGCGACCGGATGGAT
CCACAGCTTCGAAATGCTAGTGGTCCTCCGTCTCGTGCTGGGTATCGGCGAGTCGGTGGCGTACCCGTGTTATTCCAAAA
TCCTTGCCGGCCACTTCCCGGAGCATCATCGGGGTTTGGCGAATTCCTTGATCGATGCCGGCACCAAGTGTGGTCCGGCA
CTGGGCACGCTGGCGGGCGGATTGCTGATGGCGCGCTTTGGATGGCGACCCTTCTTCGTCATCCTAGGACTTGGCAGCCT
CGTGTGGCTGCCGCTGTGGTTCCGCTGGATGCCGCGCGGGCAAGGCGCTGCCGCCAGGCGCGCGGCGGATGCGCCGGGCA
TCTCCGACATCCTGCGTCATCGCGCTGCATGGGCTACCTTCGGCGGACATTTCTGCGGCAACTACTTCTGGTATTTCCTG
CTCACCTGGCTGCCGTTCTATCTGGTTCGCGAGCGCCATTTTTCAATGCGGGAGATGGCGTCGCTGGGGTCTCTCGCGTA
TCTCGTGACCGCCGCCGCGACCACGGCGGCGGGTTGGTTATCCGATCGCGCCATCGCGGCCGGAAGCGCGCCCAGTCGCG
TGCGCAAGACCTGCACCGGTTTCGGCCTGGGCTTCGCCACCATCATTCTCGGCGTCACCGCGATTCCCAACGAGACCGCG
TCCCTGGTCCTACTGCTGTTGGCCTGCGCCTCGTACGGCGTCTTCGCATCCAGTCATTGGGCCATCACCCAAACTCTGGC
CGGACCCCTTGCCGCCGGCAAGTGGACAGGCCTGCAGAATTTTGTCGCCAATCTCGCGGGGGTAGCGGCGCCGGCGATCA
CAGGCTTCGTGGTCGATTCAACCGGTCAATTCTTTTGGGCCTTCGCGGTGTCCGCCGGTGTGGCGCTCGCCGGGGCCATC
ATCTACACCTTCGGCCTGGGAAAGGTCGCGCCCGTGGAATGGGCCGAGTAA

Upstream 100 bases:

>100_bases
GGCAACGCGCTCGGGCGCGCCGAAAAGCCAACCGAAGAATCGGCAAAGACCTATACGCTCACGCCCGAGAGTCCCACCGA
AAAGCAGTAGTCTGGGAAAC

Downstream 100 bases:

>100_bases
ACAGGGGGAAAGCATGTCGCATTCGATTCGCACGCACTTACGTCAGGTGATCCTGCTTGCTTTGCCGTGTTGTATTCTGA
GCGCGGGATCCGGGCGGCAG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFSASEASTKAAPGRLPGALWGVLALLVISVAINYIDRGNLSIAAPLLKEELRISPAQLGLLLSSFFWTYSTFQIVSGWL
VDRFDVNRVIAAGFLLWSAATAATGWIHSFEMLVVLRLVLGIGESVAYPCYSKILAGHFPEHHRGLANSLIDAGTKCGPA
LGTLAGGLLMARFGWRPFFVILGLGSLVWLPLWFRWMPRGQGAAARRAADAPGISDILRHRAAWATFGGHFCGNYFWYFL
LTWLPFYLVRERHFSMREMASLGSLAYLVTAAATTAAGWLSDRAIAAGSAPSRVRKTCTGFGLGFATIILGVTAIPNETA
SLVLLLLACASYGVFASSHWAITQTLAGPLAAGKWTGLQNFVANLAGVAAPAITGFVVDSTGQFFWAFAVSAGVALAGAI
IYTFGLGKVAPVEWAE

Sequences:

>Translated_416_residues
MFSASEASTKAAPGRLPGALWGVLALLVISVAINYIDRGNLSIAAPLLKEELRISPAQLGLLLSSFFWTYSTFQIVSGWL
VDRFDVNRVIAAGFLLWSAATAATGWIHSFEMLVVLRLVLGIGESVAYPCYSKILAGHFPEHHRGLANSLIDAGTKCGPA
LGTLAGGLLMARFGWRPFFVILGLGSLVWLPLWFRWMPRGQGAAARRAADAPGISDILRHRAAWATFGGHFCGNYFWYFL
LTWLPFYLVRERHFSMREMASLGSLAYLVTAAATTAAGWLSDRAIAAGSAPSRVRKTCTGFGLGFATIILGVTAIPNETA
SLVLLLLACASYGVFASSHWAITQTLAGPLAAGKWTGLQNFVANLAGVAAPAITGFVVDSTGQFFWAFAVSAGVALAGAI
IYTFGLGKVAPVEWAE
>Mature_416_residues
MFSASEASTKAAPGRLPGALWGVLALLVISVAINYIDRGNLSIAAPLLKEELRISPAQLGLLLSSFFWTYSTFQIVSGWL
VDRFDVNRVIAAGFLLWSAATAATGWIHSFEMLVVLRLVLGIGESVAYPCYSKILAGHFPEHHRGLANSLIDAGTKCGPA
LGTLAGGLLMARFGWRPFFVILGLGSLVWLPLWFRWMPRGQGAAARRAADAPGISDILRHRAAWATFGGHFCGNYFWYFL
LTWLPFYLVRERHFSMREMASLGSLAYLVTAAATTAAGWLSDRAIAAGSAPSRVRKTCTGFGLGFATIILGVTAIPNETA
SLVLLLLACASYGVFASSHWAITQTLAGPLAAGKWTGLQNFVANLAGVAAPAITGFVVDSTGQFFWAFAVSAGVALAGAI
IYTFGLGKVAPVEWAE

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=390, Percent_Identity=26.4102564102564, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI9966811, Length=418, Percent_Identity=24.6411483253589, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21322234, Length=393, Percent_Identity=23.9185750636132, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4885441, Length=392, Percent_Identity=24.7448979591837, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI9945322, Length=404, Percent_Identity=25, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI6912666, Length=381, Percent_Identity=25.1968503937008, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI223718438, Length=372, Percent_Identity=23.9247311827957, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1789515, Length=425, Percent_Identity=27.5294117647059, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI2367379, Length=400, Percent_Identity=28, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082320, Length=427, Percent_Identity=27.6346604215457, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789152, Length=448, Percent_Identity=26.1160714285714, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI2367193, Length=408, Percent_Identity=23.2843137254902, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081723, Length=214, Percent_Identity=28.9719626168224, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535049, Length=407, Percent_Identity=24.3243243243243, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17552542, Length=401, Percent_Identity=24.1895261845387, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=389, Percent_Identity=22.107969151671, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=389, Percent_Identity=22.107969151671, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24580790, Length=364, Percent_Identity=26.0989010989011, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI28573299, Length=455, Percent_Identity=26.5934065934066, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920686, Length=402, Percent_Identity=24.6268656716418, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648416, Length=398, Percent_Identity=24.8743718592965, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21356189, Length=398, Percent_Identity=24.8743718592965, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24639764, Length=457, Percent_Identity=25.8205689277899, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583789, Length=421, Percent_Identity=23.2779097387173, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI62484226, Length=388, Percent_Identity=25, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24584153, Length=383, Percent_Identity=22.7154046997389, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24658658, Length=436, Percent_Identity=23.394495412844, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641682, Length=416, Percent_Identity=24.2788461538462, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44369; Mature: 44369

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00626 RCC1_2 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]