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The map label for this gene is rsbS [H]

Identifier: 116619665

GI number: 116619665

Start: 639246

End: 639641

Strand: Direct

Name: rsbS [H]

Synonym: Acid_0528

Alternate gene names: 116619665

Gene position: 639246-639641 (Clockwise)

Preceding gene: 116619664

Following gene: 116619666

Centisome position: 6.41

GC content: 60.86

Gene sequence:

>396_bases
ATGGGAAGATTCCTCCTGGTCACCATCCAGGTGGATATGCACGATCGTCTTGCCATGACCTTGCAGGACGACCTGACCAC
CATGATCTCCAAGATCTCAGCGCGCGGCGTGCTCCTCGATATCTCCGCGCTCGAAATGGTCGATTCCTTCATCGGGCGAG
TCATCGGCAACATCGCCTCCATGTCGCGCATCCTGGACGCGCAGACCGTGGTCGTCGGCATGCGTCCCGCGGTCGCCATC
ACTCTCGTGGAGCTCGGCCTCTCCCTCCCCGGCGTGCGTACTGCTCTCAATGTGGAAAAGGGGATGGATCTCCTTCGCCG
CTCGCTGGCCGCGGAAGAGGGGAAAGAAGCGTCGGAGCAATTGTACGCGGGGGAAATCGGGAGTGACTTCGAGTGA

Upstream 100 bases:

>100_bases
GCGTTTCGACTCGCCCTGCGCCGCCTTGGTCTGGCTGTGAAAATTGCGCCGCAAAATCTCCCCGTCAAGGAAACTCATGG
AACGGATTCCAATACTTAAG

Downstream 100 bases:

>100_bases
ATGGCGGCGCCGGATCCGAATCCCTGCCAGTCCAATCCAGTGAAGACATCGTGCTGGTCCGCCAGCGCGTCCGCACCCGC
GCCATCCGGGAGGGCTTCAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MGRFLLVTIQVDMHDRLAMTLQDDLTTMISKISARGVLLDISALEMVDSFIGRVIGNIASMSRILDAQTVVVGMRPAVAI
TLVELGLSLPGVRTALNVEKGMDLLRRSLAAEEGKEASEQLYAGEIGSDFE

Sequences:

>Translated_131_residues
MGRFLLVTIQVDMHDRLAMTLQDDLTTMISKISARGVLLDISALEMVDSFIGRVIGNIASMSRILDAQTVVVGMRPAVAI
TLVELGLSLPGVRTALNVEKGMDLLRRSLAAEEGKEASEQLYAGEIGSDFE
>Mature_130_residues
GRFLLVTIQVDMHDRLAMTLQDDLTTMISKISARGVLLDISALEMVDSFIGRVIGNIASMSRILDAQTVVVGMRPAVAIT
LVELGLSLPGVRTALNVEKGMDLLRRSLAAEEGKEASEQLYAGEIGSDFE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 14150; Mature: 14019

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRFLLVTIQVDMHDRLAMTLQDDLTTMISKISARGVLLDISALEMVDSFIGRVIGNIAS
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
MSRILDAQTVVVGMRPAVAITLVELGLSLPGVRTALNVEKGMDLLRRSLAAEEGKEASEQ
HHHHHHHHHHEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LYAGEIGSDFE
HHHCCCCCCCC
>Mature Secondary Structure 
GRFLLVTIQVDMHDRLAMTLQDDLTTMISKISARGVLLDISALEMVDSFIGRVIGNIAS
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHH
MSRILDAQTVVVGMRPAVAITLVELGLSLPGVRTALNVEKGMDLLRRSLAAEEGKEASEQ
HHHHHHHHHHEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LYAGEIGSDFE
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]