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The map label for this gene is atpA

Identifier: 116619602

GI number: 116619602

Start: 566934

End: 568472

Strand: Direct

Name: atpA

Synonym: Acid_0463

Alternate gene names: 116619602

Gene position: 566934-568472 (Clockwise)

Preceding gene: 116619601

Following gene: 116619603

Centisome position: 5.69

GC content: 61.27

Gene sequence:

>1539_bases
ATGGCTCACATTCGAGCGGACGAAATTACCAGTATTCTGCGCCAGGAGATTGAGAATTACGAGCGCGCGATCGATGTCTC
CGAGGTTGGCTCGGTGATCTCGGTGGGCGACGGTATCGCCCGCATCCATGGCCTCGAGAAGGTCATGGCCGGCGAACTCA
TCGAATTCCCGCACGACGTGGCGGGCATCGCCATGAACCTGGAAGAAGACCAGGTCGGCGCCGTGCTGCTGGGCGATTAC
ACCCTCATCAAGGAAGGCGACGAGGTCAAGCGTACCAAGCGCATCATGAGCGTTCCGGTAGGCGAAGCTCTGATCGGCCG
CGTCGTCAATGCACTCGGACAGCCGATCGATGGCAAGGGACCGATCAACGCAACGCAGTTCAACCCCATCGAACGCCTCG
CGCCAGGCGTGGTCGCGCGCCAGCCCGTGAAAGAGCCGATGATGACCGGCATCAAGGCCGTGGACGCCATGATCCCCATC
GGCCGCGGACAGCGCGAGCTGATCATCGGCGACCGCCAGACCGGTAAGACCGCAATCGCCCTCGACGCCATCATCAACCA
GAAGGGCGGCGACATGATTTGTATCTATGTCGCCATCGGCCAGAAACGTTCCACCGTCGCGCAGGTGGTGAAGACGCTCG
AAGACAACGGCGCGATGGAGTATTCCATTGTGGTGGTGGCCTCGGCCTCCGACCCCGCGCCCATGCAGTACCTGGCGCCG
TTCTCGGGCTGCGCCATCGGCGAGTATTTCCGCGATTCCAAACGCCACGCGCTCTGCATCTACGACGATCTTTCCAAGCA
CGCCGCGGCCTACCGCGAAATCTCGCTGCTGCTGCGCCGTCCTCCGGGGCGCGAAGCCTTCCCGGGCGACGTCTTCTACC
TTCACAGCCGCCTGCTGGAGCGCGCCGCCAAATTGAACAACGAACACGGCGCCGGCTCGCTGACCGCCCTGCCGTTCATT
GAAACCCAGGCGGGCGACGTTTCGGCCTACATTCCGACCAACGTGATTTCGATTACCGACGGCCAGATCTTCCTCGAAGC
CGATCTCTTCAATTCCAACCAGCGTCCCGCCATCAACGTCGGCATCTCCGTGAGCCGCGTCGGCGGCAACGCGCAGACCA
AGGCGATGAAATCGATCGCCGGCGGCTTGCGCCTGGATCTCGCGCAGTACCGCGAACTGGCGGCCTTCGCCCAGTTCGGC
AGCGACCTCGACAAATCGTCACAGGCGCAGTTGAATCGCGGACGCCACCTGGTGGAGATCCTCAAGCAGGATCAATATCA
GCCGCTACCGCTTGAAAAACAGATCATGATCATCTGGGCCGGCACCAAAGGCTATTTGGATGACATTCCAGTGGAGTTGT
GCCGCAAGTTCGAAGCCGAACTGTACCGCTTCAGCGAGAATGCGCACCGCCCCGTGCTGGACGAAATCAAAACCAAGAAG
GCTCTGGATCCCGACCTCACCGCCAAGGTGAAAGGCATCGTCGAAGAATTCAAGGGCCGCTTCATGGCGGAGAACGCACC
GGCTAAAGCCCATGCCTAG

Upstream 100 bases:

>100_bases
GGTCGCGCGGATCGGCTCCACGGTTTACGACGGCAGTGTGCGCGGCCAGTTGCAGACGCTGGAACGGCGCCTCAGTACGG
AACGATAATCGGAAGGAAAT

Downstream 100 bases:

>100_bases
CTTGATCGACATCCGGCGGCGCATTCGCTCCGTCAAGAATACGCAGCAGATCACCAAGGCCATGAAGATGGTCTCGGCGG
CCAAACTGCGCCGGGCGCAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAHIRADEITSILRQEIENYERAIDVSEVGSVISVGDGIARIHGLEKVMAGELIEFPHDVAGIAMNLEEDQVGAVLLGDY
TLIKEGDEVKRTKRIMSVPVGEALIGRVVNALGQPIDGKGPINATQFNPIERLAPGVVARQPVKEPMMTGIKAVDAMIPI
GRGQRELIIGDRQTGKTAIALDAIINQKGGDMICIYVAIGQKRSTVAQVVKTLEDNGAMEYSIVVVASASDPAPMQYLAP
FSGCAIGEYFRDSKRHALCIYDDLSKHAAAYREISLLLRRPPGREAFPGDVFYLHSRLLERAAKLNNEHGAGSLTALPFI
ETQAGDVSAYIPTNVISITDGQIFLEADLFNSNQRPAINVGISVSRVGGNAQTKAMKSIAGGLRLDLAQYRELAAFAQFG
SDLDKSSQAQLNRGRHLVEILKQDQYQPLPLEKQIMIIWAGTKGYLDDIPVELCRKFEAELYRFSENAHRPVLDEIKTKK
ALDPDLTAKVKGIVEEFKGRFMAENAPAKAHA

Sequences:

>Translated_512_residues
MAHIRADEITSILRQEIENYERAIDVSEVGSVISVGDGIARIHGLEKVMAGELIEFPHDVAGIAMNLEEDQVGAVLLGDY
TLIKEGDEVKRTKRIMSVPVGEALIGRVVNALGQPIDGKGPINATQFNPIERLAPGVVARQPVKEPMMTGIKAVDAMIPI
GRGQRELIIGDRQTGKTAIALDAIINQKGGDMICIYVAIGQKRSTVAQVVKTLEDNGAMEYSIVVVASASDPAPMQYLAP
FSGCAIGEYFRDSKRHALCIYDDLSKHAAAYREISLLLRRPPGREAFPGDVFYLHSRLLERAAKLNNEHGAGSLTALPFI
ETQAGDVSAYIPTNVISITDGQIFLEADLFNSNQRPAINVGISVSRVGGNAQTKAMKSIAGGLRLDLAQYRELAAFAQFG
SDLDKSSQAQLNRGRHLVEILKQDQYQPLPLEKQIMIIWAGTKGYLDDIPVELCRKFEAELYRFSENAHRPVLDEIKTKK
ALDPDLTAKVKGIVEEFKGRFMAENAPAKAHA
>Mature_511_residues
AHIRADEITSILRQEIENYERAIDVSEVGSVISVGDGIARIHGLEKVMAGELIEFPHDVAGIAMNLEEDQVGAVLLGDYT
LIKEGDEVKRTKRIMSVPVGEALIGRVVNALGQPIDGKGPINATQFNPIERLAPGVVARQPVKEPMMTGIKAVDAMIPIG
RGQRELIIGDRQTGKTAIALDAIINQKGGDMICIYVAIGQKRSTVAQVVKTLEDNGAMEYSIVVVASASDPAPMQYLAPF
SGCAIGEYFRDSKRHALCIYDDLSKHAAAYREISLLLRRPPGREAFPGDVFYLHSRLLERAAKLNNEHGAGSLTALPFIE
TQAGDVSAYIPTNVISITDGQIFLEADLFNSNQRPAINVGISVSRVGGNAQTKAMKSIAGGLRLDLAQYRELAAFAQFGS
DLDKSSQAQLNRGRHLVEILKQDQYQPLPLEKQIMIIWAGTKGYLDDIPVELCRKFEAELYRFSENAHRPVLDEIKTKKA
LDPDLTAKVKGIVEEFKGRFMAENAPAKAHA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=61.1111111111111, Blast_Score=619, Evalue=1e-177,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=61.1111111111111, Blast_Score=619, Evalue=1e-177,
Organism=Homo sapiens, GI19913426, Length=308, Percent_Identity=29.8701298701299, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI19913428, Length=308, Percent_Identity=29.2207792207792, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI32189394, Length=372, Percent_Identity=24.4623655913978, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI19913424, Length=265, Percent_Identity=27.9245283018868, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1790172, Length=507, Percent_Identity=57.0019723865878, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1788251, Length=361, Percent_Identity=28.2548476454294, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790170, Length=363, Percent_Identity=25.068870523416, Blast_Score=101, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=509, Percent_Identity=60.7072691552063, Blast_Score=633, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=509, Percent_Identity=60.7072691552063, Blast_Score=630, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=509, Percent_Identity=56.7779960707269, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17570191, Length=307, Percent_Identity=30.9446254071661, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=387, Percent_Identity=27.1317829457364, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=415, Percent_Identity=23.855421686747, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=66.6666666666667, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988068, Length=79, Percent_Identity=43.0379746835443, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=264, Percent_Identity=26.8939393939394, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=59.7609561752988, Blast_Score=607, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319603, Length=363, Percent_Identity=28.6501377410468, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6322581, Length=408, Percent_Identity=24.0196078431373, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=60.3960396039604, Blast_Score=613, Evalue=1e-175,
Organism=Drosophila melanogaster, GI281361666, Length=307, Percent_Identity=29.3159609120521, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24646341, Length=307, Percent_Identity=29.3159609120521, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17136796, Length=307, Percent_Identity=29.3159609120521, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24638766, Length=411, Percent_Identity=24.0875912408759, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574560, Length=385, Percent_Identity=25.1948051948052, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583992, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI20129479, Length=258, Percent_Identity=29.0697674418605, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24583988, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583986, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583984, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_SOLUE (Q02BU3)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_821758.1
- ProteinModelPortal:   Q02BU3
- SMR:   Q02BU3
- STRING:   Q02BU3
- GeneID:   4431466
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0463
- NMPDR:   fig|234267.9.peg.436
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q02BU3
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55877; Mature: 55746

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHIRADEITSILRQEIENYERAIDVSEVGSVISVGDGIARIHGLEKVMAGELIEFPHDV
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCH
AGIAMNLEEDQVGAVLLGDYTLIKEGDEVKRTKRIMSVPVGEALIGRVVNALGQPIDGKG
HHEEEECCCCCCCEEEECCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PINATQFNPIERLAPGVVARQPVKEPMMTGIKAVDAMIPIGRGQRELIIGDRQTGKTAIA
CCCCCCCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEE
LDAIINQKGGDMICIYVAIGQKRSTVAQVVKTLEDNGAMEYSIVVVASASDPAPMQYLAP
EHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHCC
FSGCAIGEYFRDSKRHALCIYDDLSKHAAAYREISLLLRRPPGREAFPGDVFYLHSRLLE
CCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLNNEHGAGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLEADLFNSNQRPAINV
HHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEECCCCCCCEEEE
GISVSRVGGNAQTKAMKSIAGGLRLDLAQYRELAAFAQFGSDLDKSSQAQLNRGRHLVEI
CEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LKQDQYQPLPLEKQIMIIWAGTKGYLDDIPVELCRKFEAELYRFSENAHRPVLDEIKTKK
HHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ALDPDLTAKVKGIVEEFKGRFMAENAPAKAHA
CCCCCHHHHHHHHHHHHCCCEEECCCCCCCCC
>Mature Secondary Structure 
AHIRADEITSILRQEIENYERAIDVSEVGSVISVGDGIARIHGLEKVMAGELIEFPHDV
CCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCH
AGIAMNLEEDQVGAVLLGDYTLIKEGDEVKRTKRIMSVPVGEALIGRVVNALGQPIDGKG
HHEEEECCCCCCCEEEECCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
PINATQFNPIERLAPGVVARQPVKEPMMTGIKAVDAMIPIGRGQRELIIGDRQTGKTAIA
CCCCCCCCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEE
LDAIINQKGGDMICIYVAIGQKRSTVAQVVKTLEDNGAMEYSIVVVASASDPAPMQYLAP
EHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHCC
FSGCAIGEYFRDSKRHALCIYDDLSKHAAAYREISLLLRRPPGREAFPGDVFYLHSRLLE
CCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLNNEHGAGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLEADLFNSNQRPAINV
HHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEECCCCCCCEEEE
GISVSRVGGNAQTKAMKSIAGGLRLDLAQYRELAAFAQFGSDLDKSSQAQLNRGRHLVEI
CEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LKQDQYQPLPLEKQIMIIWAGTKGYLDDIPVELCRKFEAELYRFSENAHRPVLDEIKTKK
HHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ALDPDLTAKVKGIVEEFKGRFMAENAPAKAHA
CCCCCHHHHHHHHHHHHCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA