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The map label for this gene is glsA [H]

Identifier: 116619585

GI number: 116619585

Start: 551155

End: 552240

Strand: Direct

Name: glsA [H]

Synonym: Acid_0446

Alternate gene names: 116619585

Gene position: 551155-552240 (Clockwise)

Preceding gene: 116619578

Following gene: 116619586

Centisome position: 5.53

GC content: 61.23

Gene sequence:

>1086_bases
ATGGCTCAAAATACGTCCTACAAACTGCTAGCTGCTGCAACCTTGCTGGCAACGGGGCTGGTGCTGACCAATCTTCCCGG
TGAGCAAGCCGCGGCCGGCCGGGCTGCCCGGCTTAGCACGAACCGCAGCCCGGTAGCTCCCGCGGACGCCCAGATCCAGG
CCGCCATCAATGAGGCCTACGCGCGCTATCGCAGCGACACAAGCGGCAAGAACGCCGATTACATTCCCTATCTCGCCCAG
GTGGACTCGAAGTTGTTCGGCATCGCCGCCGTCACTACCGACGGCCGCGTCTTCACCGCCGGCGACGTGGATTTTTCGTT
CTCCATGCAGTCCATTTCCAAAGTCTTTACGCTTGCCCTCGCCATGGAGGAATTGGGCGCGGACAAGGTCTTCGAACGGA
TCGGCGCCGAGCCCACCGGCCGGCCCTTCAACTCCGTCACCGCAGTCGAGGACATGCCGGGTCACACAGCCAATCCCTTC
GTCAACGCAGGCGCCATCGCCACCACCAGTCTCGTGTCAGGCTCCGACCCGAATGCCAAGTGGGATAAGATTCTCGCCTT
CTACAACAAGGTAGCGGGCGAAAAGCTCAAGCTGATCGACGACGTCTACAAATCGGAGGCCGCGACCAACATGCACAACA
AGGCCATCGCGACCCTGCTCGCCAGTTACGAGCGCATGTATTCCGACCCGCTCGAAGCTACTGACATTTACACCAGGCAG
TGCTCCGTCGGCGTAACCGCGAAAGAGCTTGCCGTAATGGGTGCCACGCTCGCCGATCAGGGCCGAAATCCGATCACCGG
CATACAGGTAATTAAGCCCGAGAATGTCCCGCACATCCTGGCCGTCATGTCGATGGCCGGCCTGTACGATGGCTCGGGCG
GCTGGGCCTGGAAGGTCGGTCTTCCCGCCAAGAGCGGTGTCGGCGGCGGCATCCTCGCCATTGTCCCCGGGAAGGGCGCG
ATCGTCGGCTTTGCTCCGCGCCTGGACAAAGCCGGCAATAGTGTGAAAGCGCAGAAGTCGATCGCCTATGTTGCAGACAA
GCTCGACATCAATTTGTATTCCCCGGGTTCGGTCGGCCTCAAGTGA

Upstream 100 bases:

>100_bases
TGGCGCAACCCCATCCACCCGGCATCGTGACACGCTGAGGGCAAGGTAACGGGACCCGCGGAAACTCATCCAGCGGCCAC
CAATCTTTAGGAGATCGACC

Downstream 100 bases:

>100_bases
ACCTCGTCCGTTTCCTGAGCGCCAAGTTCCGTTACCTGGCCTATCTCTGGAGTACGAACGTAGCCAGGGTCTGGCCGCTC
AAGTGGTGGTCGCCGGCATC

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAQNTSYKLLAAATLLATGLVLTNLPGEQAAAGRAARLSTNRSPVAPADAQIQAAINEAYARYRSDTSGKNADYIPYLAQ
VDSKLFGIAAVTTDGRVFTAGDVDFSFSMQSISKVFTLALAMEELGADKVFERIGAEPTGRPFNSVTAVEDMPGHTANPF
VNAGAIATTSLVSGSDPNAKWDKILAFYNKVAGEKLKLIDDVYKSEAATNMHNKAIATLLASYERMYSDPLEATDIYTRQ
CSVGVTAKELAVMGATLADQGRNPITGIQVIKPENVPHILAVMSMAGLYDGSGGWAWKVGLPAKSGVGGGILAIVPGKGA
IVGFAPRLDKAGNSVKAQKSIAYVADKLDINLYSPGSVGLK

Sequences:

>Translated_361_residues
MAQNTSYKLLAAATLLATGLVLTNLPGEQAAAGRAARLSTNRSPVAPADAQIQAAINEAYARYRSDTSGKNADYIPYLAQ
VDSKLFGIAAVTTDGRVFTAGDVDFSFSMQSISKVFTLALAMEELGADKVFERIGAEPTGRPFNSVTAVEDMPGHTANPF
VNAGAIATTSLVSGSDPNAKWDKILAFYNKVAGEKLKLIDDVYKSEAATNMHNKAIATLLASYERMYSDPLEATDIYTRQ
CSVGVTAKELAVMGATLADQGRNPITGIQVIKPENVPHILAVMSMAGLYDGSGGWAWKVGLPAKSGVGGGILAIVPGKGA
IVGFAPRLDKAGNSVKAQKSIAYVADKLDINLYSPGSVGLK
>Mature_360_residues
AQNTSYKLLAAATLLATGLVLTNLPGEQAAAGRAARLSTNRSPVAPADAQIQAAINEAYARYRSDTSGKNADYIPYLAQV
DSKLFGIAAVTTDGRVFTAGDVDFSFSMQSISKVFTLALAMEELGADKVFERIGAEPTGRPFNSVTAVEDMPGHTANPFV
NAGAIATTSLVSGSDPNAKWDKILAFYNKVAGEKLKLIDDVYKSEAATNMHNKAIATLLASYERMYSDPLEATDIYTRQC
SVGVTAKELAVMGATLADQGRNPITGIQVIKPENVPHILAVMSMAGLYDGSGGWAWKVGLPAKSGVGGGILAIVPGKGAI
VGFAPRLDKAGNSVKAQKSIAYVADKLDINLYSPGSVGLK

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=310, Percent_Identity=39.6774193548387, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI20336214, Length=296, Percent_Identity=37.1621621621622, Blast_Score=181, Evalue=7e-46,
Organism=Escherichia coli, GI1786693, Length=303, Percent_Identity=52.4752475247525, Blast_Score=324, Evalue=5e-90,
Organism=Escherichia coli, GI1787804, Length=288, Percent_Identity=38.1944444444444, Blast_Score=196, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17532727, Length=292, Percent_Identity=38.013698630137, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI193204073, Length=320, Percent_Identity=33.4375, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI193204075, Length=322, Percent_Identity=33.2298136645963, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17507019, Length=314, Percent_Identity=33.4394904458599, Blast_Score=171, Evalue=5e-43,
Organism=Drosophila melanogaster, GI281363241, Length=317, Percent_Identity=33.7539432176656, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24653162, Length=317, Percent_Identity=33.7539432176656, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653164, Length=317, Percent_Identity=33.7539432176656, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363239, Length=317, Percent_Identity=33.7539432176656, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653158, Length=306, Percent_Identity=34.3137254901961, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI116008307, Length=317, Percent_Identity=33.7539432176656, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653156, Length=306, Percent_Identity=34.3137254901961, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653166, Length=306, Percent_Identity=34.3137254901961, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 37825; Mature: 37694

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNTSYKLLAAATLLATGLVLTNLPGEQAAAGRAARLSTNRSPVAPADAQIQAAINEAY
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHEECCCCCCCCCCCHHHHHHHHHHH
ARYRSDTSGKNADYIPYLAQVDSKLFGIAAVTTDGRVFTAGDVDFSFSMQSISKVFTLAL
HHHCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCEEEEECCCCEEHHHHHHHHHHHHHH
AMEELGADKVFERIGAEPTGRPFNSVTAVEDMPGHTANPFVNAGAIATTSLVSGSDPNAK
HHHHHCHHHHHHHHCCCCCCCCCCCEEEHHCCCCCCCCCCCCCCCHHHHHEECCCCCCHH
WDKILAFYNKVAGEKLKLIDDVYKSEAATNMHNKAIATLLASYERMYSDPLEATDIYTRQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
CSVGVTAKELAVMGATLADQGRNPITGIQVIKPENVPHILAVMSMAGLYDGSGGWAWKVG
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCEECCCCEEEEEC
LPAKSGVGGGILAIVPGKGAIVGFAPRLDKAGNSVKAQKSIAYVADKLDINLYSPGSVGL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCC
K
C
>Mature Secondary Structure 
AQNTSYKLLAAATLLATGLVLTNLPGEQAAAGRAARLSTNRSPVAPADAQIQAAINEAY
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHEECCCCCCCCCCCHHHHHHHHHHH
ARYRSDTSGKNADYIPYLAQVDSKLFGIAAVTTDGRVFTAGDVDFSFSMQSISKVFTLAL
HHHCCCCCCCCCCCCHHHHHHCCCCEEEEEEECCCEEEEECCCCEEHHHHHHHHHHHHHH
AMEELGADKVFERIGAEPTGRPFNSVTAVEDMPGHTANPFVNAGAIATTSLVSGSDPNAK
HHHHHCHHHHHHHHCCCCCCCCCCCEEEHHCCCCCCCCCCCCCCCHHHHHEECCCCCCHH
WDKILAFYNKVAGEKLKLIDDVYKSEAATNMHNKAIATLLASYERMYSDPLEATDIYTRQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
CSVGVTAKELAVMGATLADQGRNPITGIQVIKPENVPHILAVMSMAGLYDGSGGWAWKVG
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCEECCCCEEEEEC
LPAKSGVGGGILAIVPGKGAIVGFAPRLDKAGNSVKAQKSIAYVADKLDINLYSPGSVGL
CCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA