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The map label for this gene is iolG [H]

Identifier: 116619556

GI number: 116619556

Start: 519360

End: 520337

Strand: Direct

Name: iolG [H]

Synonym: Acid_0417

Alternate gene names: 116619556

Gene position: 519360-520337 (Clockwise)

Preceding gene: 116619554

Following gene: 116619557

Centisome position: 5.21

GC content: 66.77

Gene sequence:

>978_bases
TTGCGAGCGGCGATCGTGGGCTGCGGTCTGATTGGGCGGAAGCGCGCCGGCGCTCTTCCGGCGGGCACGGTCACAGTCTG
CTGCGACGTGAGCGCCGAACGCGCCACTCAACTGGCCGCCGCAACCCGGGGCGCGGCCCCTTCCGTCGATTGGGAAGCGA
CCGTCTGCCGAGGCGATGTGGATGCCGTCTTCGTGGCTACGACGCACGATCAACTGGCGCCGGTGGCGGCCGCGGCTGCT
GCCGCTGGGAAGCACGTGCTGATAGAGAAGCCAGGCGCGCGCTCCGTAGGCGAGCTGGACGCGGTCGCCGCTGCCGCCGC
GAAATCGGGAGCCCTGGTGCGGGTCGGGTTCAATCACCGGTATCACCGCGCCTTTCGGAAGGCCCGCGAGATCTTCGAGA
GCGGAGCGCTGGGCGAGATGATGTTCATCCGCGGCCGTTACGGACATGGCGGCCGCCCGGGCTACGATCGCGAATGGCGT
GCCGTGCCCGCGCTCTCCGGCGGCGGTGAGCTGATCGATCAAGGGGCGCACCTGATCGACCTCTCCCGCTGGTTCCTCGG
CGATTTCCCCGGCGTCCGCGGCAGCGCCCGTACGTATTTCTGGGATATGCCGGTGGAGGACAACGGATTTCTGCTGCTCG
AAACCGCGCGCGGACAGGTGGCCTTCCTCCACGCCAGTTGGACCGAGTGGAAGAATCTCTTCAGCTTCGAAATCTCCGGC
CGCGCCGGCAAGCTGGAAATCAGCGGCCTCGGCGGCAGCTATGGTCCGGAGCGCCTGACCTGGTACAAAATGTCCGCCGA
GATGGGACCACCAGAAACCTCCGCGTGGGAGTATCCCATGGCGGATGACTCCTGGCATGCCGAGAACACCGCCTTCCTTG
AAGATATCCGGCTTGTCCGGCAGCCCGACCCAGGCATTGCCGACGCACAGGCAGCCCTGCGAATTATCGAATCCGTCTAC
CGCGAGCCGCACGCATGA

Upstream 100 bases:

>100_bases
CATGCCTCAATTCGAGCAGCGGCCATACCGGACCGCCACGCCACTCGCCCAATCAGAGTCCGCCCACCAGTTACAATGCA
TTTTGACTCCGAAACCATCT

Downstream 100 bases:

>100_bases
TCATCACCCGCACCCCTTTGCGCATTTCCCTTGGAGGCGGCGGCACCGACCTCCCTTCGTATTACCGCGAGCACGGAGGC
TTCGTGCTTTCCGCGGCCAT

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRAAIVGCGLIGRKRAGALPAGTVTVCCDVSAERATQLAAATRGAAPSVDWEATVCRGDVDAVFVATTHDQLAPVAAAAA
AAGKHVLIEKPGARSVGELDAVAAAAAKSGALVRVGFNHRYHRAFRKAREIFESGALGEMMFIRGRYGHGGRPGYDREWR
AVPALSGGGELIDQGAHLIDLSRWFLGDFPGVRGSARTYFWDMPVEDNGFLLLETARGQVAFLHASWTEWKNLFSFEISG
RAGKLEISGLGGSYGPERLTWYKMSAEMGPPETSAWEYPMADDSWHAENTAFLEDIRLVRQPDPGIADAQAALRIIESVY
REPHA

Sequences:

>Translated_325_residues
MRAAIVGCGLIGRKRAGALPAGTVTVCCDVSAERATQLAAATRGAAPSVDWEATVCRGDVDAVFVATTHDQLAPVAAAAA
AAGKHVLIEKPGARSVGELDAVAAAAAKSGALVRVGFNHRYHRAFRKAREIFESGALGEMMFIRGRYGHGGRPGYDREWR
AVPALSGGGELIDQGAHLIDLSRWFLGDFPGVRGSARTYFWDMPVEDNGFLLLETARGQVAFLHASWTEWKNLFSFEISG
RAGKLEISGLGGSYGPERLTWYKMSAEMGPPETSAWEYPMADDSWHAENTAFLEDIRLVRQPDPGIADAQAALRIIESVY
REPHA
>Mature_325_residues
MRAAIVGCGLIGRKRAGALPAGTVTVCCDVSAERATQLAAATRGAAPSVDWEATVCRGDVDAVFVATTHDQLAPVAAAAA
AAGKHVLIEKPGARSVGELDAVAAAAAKSGALVRVGFNHRYHRAFRKAREIFESGALGEMMFIRGRYGHGGRPGYDREWR
AVPALSGGGELIDQGAHLIDLSRWFLGDFPGVRGSARTYFWDMPVEDNGFLLLETARGQVAFLHASWTEWKNLFSFEISG
RAGKLEISGLGGSYGPERLTWYKMSAEMGPPETSAWEYPMADDSWHAENTAFLEDIRLVRQPDPGIADAQAALRIIESVY
REPHA

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=253, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 35013; Mature: 35013

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAIVGCGLIGRKRAGALPAGTVTVCCDVSAERATQLAAATRGAAPSVDWEATVCRGDV
CCCEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCEEEECCCC
DAVFVATTHDQLAPVAAAAAAAGKHVLIEKPGARSVGELDAVAAAAAKSGALVRVGFNHR
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCH
YHRAFRKAREIFESGALGEMMFIRGRYGHGGRPGYDREWRAVPALSGGGELIDQGAHLID
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCHHHHCCCCEEE
LSRWFLGDFPGVRGSARTYFWDMPVEDNGFLLLETARGQVAFLHASWTEWKNLFSFEISG
HHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCEEEEEEECHHHHCCEEEEEECC
RAGKLEISGLGGSYGPERLTWYKMSAEMGPPETSAWEYPMADDSWHAENTAFLEDIRLVR
CCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
QPDPGIADAQAALRIIESVYREPHA
CCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRAAIVGCGLIGRKRAGALPAGTVTVCCDVSAERATQLAAATRGAAPSVDWEATVCRGDV
CCCEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCEEEECCCC
DAVFVATTHDQLAPVAAAAAAAGKHVLIEKPGARSVGELDAVAAAAAKSGALVRVGFNHR
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCH
YHRAFRKAREIFESGALGEMMFIRGRYGHGGRPGYDREWRAVPALSGGGELIDQGAHLID
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCHHHHCCCCEEE
LSRWFLGDFPGVRGSARTYFWDMPVEDNGFLLLETARGQVAFLHASWTEWKNLFSFEISG
HHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCEEEEEEECHHHHCCEEEEEECC
RAGKLEISGLGGSYGPERLTWYKMSAEMGPPETSAWEYPMADDSWHAENTAFLEDIRLVR
CCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
QPDPGIADAQAALRIIESVYREPHA
CCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA