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The map label for this gene is pimA [H]

Identifier: 116619445

GI number: 116619445

Start: 403641

End: 404696

Strand: Direct

Name: pimA [H]

Synonym: Acid_0304

Alternate gene names: 116619445

Gene position: 403641-404696 (Clockwise)

Preceding gene: 116619439

Following gene: 116619448

Centisome position: 4.05

GC content: 65.15

Gene sequence:

>1056_bases
ATGATGGATACCTTGACGTTTCGCTTTCTCACCTCGACGCCCCAGGACATTACCCGCGGCAGCGGCACGTATGTCGGCAT
CTCGGTTCTCGCCGGGGCCTTGCGCGACCTCGGCCACCAGGTCGATTTTGAATCGCCGCGCCGCCACTTTCCTGTCTACA
CGGTGGAGCGGCTGTGGTTTAATCGGGGCCTCCGCCCTTCCCCACGGCACAACATTACGGTGGGCTACGACATGGATGGC
TACCGCATCGCAGGCGAGCCGGGACACGTGGCGTCGCTGAAGGGTGTGATTGCCGACGAGGTGCGGTTCGAAAGCGGCCT
GACCCGCGCTACGATGTCGCTGCAGGCGCGCTGCGAGCGTTTGCACGTCCGCCGCGCATCGCGCGTCGTGGTCACCAGCC
GCTACTCCGGCGAGCGGGCGCAGGAAATGTACGGTCTTCCTGATTTTCCAATCGTGGTGCCGGAACTGATTGATTTGCAG
ACCTGGCGCCGCCATCTGGACGCAGCGCCGGCCGCGGAATCCAGTCGCTTCACGGTGCTCTATGTGGGACGATTCTACCG
GCGCAAGCGCGTCAACCTGCTGCTCGATGCGGCTGTCGAACTGCGCGCCGCGATACCTGAACTCGAGATCCGCATCGTCG
GCAATGGCCCTTGCGATGCGGCGTGGCGCGCGCACTCGGCCCAATCCAAGTTGGAGGGGACCGTGACCTGGCTGGGAGAC
GTATCGCGTGCAGCCCTCGCGGCGGAATACAGCCGCGCTGATGTTTTCTGCCTGCCGAGCGTGCAGGAGGGTTTTGGCAT
CGTGCTGTTGGAGGCGATGGCGGCCGGCAAGGCGATTGTCGCGGCGCGGGCCGCCGCGATCCCGGAGGTCGTGCCCCATG
CGACGCTGGTCGATCGGGAAAGTGGGAGTGCGCTGGCGGAGGGGATTCTCAATCTCTACGCCTCGCCTGCTTTGCGCTCC
AGCCAATCCGCGCATGGGCTCGTTCGCGTAGAGCAGTTCGACGCCCGGTGCGTGGCACGCCTCTTCGTGGAGGCGGTCAG
CGGTAAGTCAGGGTGA

Upstream 100 bases:

>100_bases
TAAGAAGGCAGACGGCATTAGGCATTACGATTCCAGTGTAGCGTTGGAATGCGGAAACTCGATTCTGACGGCTTCGGCAG
TCCCGGCAAGCGATGCCAAA

Downstream 100 bases:

>100_bases
TCGGCTGCACCACCTGCTGTGGCGAAGCACCCTGGAGGGCTCCCGCGACCGCGTAGGTCGCGCGATCCTGCTCGGCCACT
GTCTCTACGAGGTTGACGCG

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MMDTLTFRFLTSTPQDITRGSGTYVGISVLAGALRDLGHQVDFESPRRHFPVYTVERLWFNRGLRPSPRHNITVGYDMDG
YRIAGEPGHVASLKGVIADEVRFESGLTRATMSLQARCERLHVRRASRVVVTSRYSGERAQEMYGLPDFPIVVPELIDLQ
TWRRHLDAAPAAESSRFTVLYVGRFYRRKRVNLLLDAAVELRAAIPELEIRIVGNGPCDAAWRAHSAQSKLEGTVTWLGD
VSRAALAAEYSRADVFCLPSVQEGFGIVLLEAMAAGKAIVAARAAAIPEVVPHATLVDRESGSALAEGILNLYASPALRS
SQSAHGLVRVEQFDARCVARLFVEAVSGKSG

Sequences:

>Translated_351_residues
MMDTLTFRFLTSTPQDITRGSGTYVGISVLAGALRDLGHQVDFESPRRHFPVYTVERLWFNRGLRPSPRHNITVGYDMDG
YRIAGEPGHVASLKGVIADEVRFESGLTRATMSLQARCERLHVRRASRVVVTSRYSGERAQEMYGLPDFPIVVPELIDLQ
TWRRHLDAAPAAESSRFTVLYVGRFYRRKRVNLLLDAAVELRAAIPELEIRIVGNGPCDAAWRAHSAQSKLEGTVTWLGD
VSRAALAAEYSRADVFCLPSVQEGFGIVLLEAMAAGKAIVAARAAAIPEVVPHATLVDRESGSALAEGILNLYASPALRS
SQSAHGLVRVEQFDARCVARLFVEAVSGKSG
>Mature_351_residues
MMDTLTFRFLTSTPQDITRGSGTYVGISVLAGALRDLGHQVDFESPRRHFPVYTVERLWFNRGLRPSPRHNITVGYDMDG
YRIAGEPGHVASLKGVIADEVRFESGLTRATMSLQARCERLHVRRASRVVVTSRYSGERAQEMYGLPDFPIVVPELIDLQ
TWRRHLDAAPAAESSRFTVLYVGRFYRRKRVNLLLDAAVELRAAIPELEIRIVGNGPCDAAWRAHSAQSKLEGTVTWLGD
VSRAALAAEYSRADVFCLPSVQEGFGIVLLEAMAAGKAIVAARAAAIPEVVPHATLVDRESGSALAEGILNLYASPALRS
SQSAHGLVRVEQFDARCVARLFVEAVSGKSG

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 38473; Mature: 38473

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDTLTFRFLTSTPQDITRGSGTYVGISVLAGALRDLGHQVDFESPRRHFPVYTVERLWF
CCCCEEEEEECCCCHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
NRGLRPSPRHNITVGYDMDGYRIAGEPGHVASLKGVIADEVRFESGLTRATMSLQARCER
HCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LHVRRASRVVVTSRYSGERAQEMYGLPDFPIVVPELIDLQTWRRHLDAAPAAESSRFTVL
HHHHHHCEEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
YVGRFYRRKRVNLLLDAAVELRAAIPELEIRIVGNGPCDAAWRAHSAQSKLEGTVTWLGD
EEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCHHHHHCEEEEEHHH
VSRAALAAEYSRADVFCLPSVQEGFGIVLLEAMAAGKAIVAARAAAIPEVVPHATLVDRE
HHHHHHHHHHCCCCEEECCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHCCCCEEEECC
SGSALAEGILNLYASPALRSSQSAHGLVRVEQFDARCVARLFVEAVSGKSG
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMDTLTFRFLTSTPQDITRGSGTYVGISVLAGALRDLGHQVDFESPRRHFPVYTVERLWF
CCCCEEEEEECCCCHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
NRGLRPSPRHNITVGYDMDGYRIAGEPGHVASLKGVIADEVRFESGLTRATMSLQARCER
HCCCCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LHVRRASRVVVTSRYSGERAQEMYGLPDFPIVVPELIDLQTWRRHLDAAPAAESSRFTVL
HHHHHHCEEEEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
YVGRFYRRKRVNLLLDAAVELRAAIPELEIRIVGNGPCDAAWRAHSAQSKLEGTVTWLGD
EEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCHHHHHCEEEEEHHH
VSRAALAAEYSRADVFCLPSVQEGFGIVLLEAMAAGKAIVAARAAAIPEVVPHATLVDRE
HHHHHHHHHHCCCCEEECCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHCCCCEEEECC
SGSALAEGILNLYASPALRSSQSAHGLVRVEQFDARCVARLFVEAVSGKSG
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]