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The map label for this gene is xseA [H]

Identifier: 116619439

GI number: 116619439

Start: 398151

End: 399518

Strand: Direct

Name: xseA [H]

Synonym: Acid_0298

Alternate gene names: 116619439

Gene position: 398151-399518 (Clockwise)

Preceding gene: 116619438

Following gene: 116619445

Centisome position: 4.0

GC content: 64.91

Gene sequence:

>1368_bases
GTGGAGCAATTCGACCTGGGCTTCGAGCTCTTTCCGGAAAAGCGCGTCTACACCGTCGGGGAGTTGAACGGTGCGATTCG
AAAGGCGCTGGACGGCCAGTTCACCGATATCAGGGTTGCCGGCGAGATCTCAAATCTTAGACTGGCTGCCAGCGGCCACT
ATTATTTCAACCTGAAGGAACGCGACTCCATAGTCAAAGCAGTGGCCTACCGTTCCGCCGCACGGTTCTGGAAGTTCAAG
CCGCAAGACGGACTCGCGGTAATAGCACGCGGAAGCCTCGATATCTACGAAGTCCGCGGCGAGTATCAGCTTCAGGTTGA
ATCATTGGAGCCGCAAGGCCTCGGCGCGTTGCAACTCGCGTTCGAACAGCTCAAGAAAAAACTGGCAGCCGAAGGGTTGT
TCGCGGCCGAGCGCAAACGTCCGCTGCCGCGCTTCCCGCGCCGCATCGGCATCGTCACCTCGCCGCGCGGCGCGGCGATT
GCGGACATGATCCAGATTCTCTCGCGCCGTTTCCCGGGACTTCACATACGGCTCTTCCCGGCGCTGGTGCAGGGCGAAGG
CTCGGTGGAGGAGGTCTGCCGCGCGATCGAATATTTCAGCCGCACCGGGTGGGCGGACGTGTTGATCGTGGGCCGCGGGG
GAGGCTCTCTGGAAGACCTCTGGACCTTCAATACGGAAGCGGTGGCGCGCGCGATTGCGGCCTGTTCGGTGCCGGTGATT
TCCGCGGTGGGCCACGAAACCGATATCACGATCGCCGATTTTGTGGCCGACCTGCGCGCCCCTACGCCTTCGGCGGCCGC
CGAAATGGTAGTCTGCACGCGCGACGAGCTGCTGGACCGCATTGGGGCCGCGCGCGCCAAGGCCGCGCAGGGAGCACGCT
ACCGGATCGCCATGCTGGAACGCCGCCTGCGGCTGCAAGGCATCGACCGCGCGCTCGGGACCCTGCACCGGCGAGTGGGG
CGGGGGCTGCAGCGAATCGACGAACAGGAATACCGCATGCGGGAGCGGATCAGGATCGGGTTGGATGGGCGGGAGCGAGT
CCGCAGGGCGCTCGAACTGCGATTGCGCCGGTTCGATGTCCGGCCGCGCCTGGCCGCCGACCGGCGGCGCATGGAACTGG
CGCGGAACTCCGCCTTGCAGGTGATGCACGCACGTTTGGGGCAGGATCGAAACCGCCTCGGGCAACTGGCCGCGACTCTT
TCACAGCTCAGCCCCCTGCGCGTCCTGGAGAGGGGTTATGCGATCGTCTCCAACGACGGAGGCATTCTGAAGGACGCCGC
CGCGGTGCCCGCCAATTCCCAGATCCGAGTGCGTCTGGCAAAGGGCGGGCTGGAGGCGGTGGTGACGGCGTCGACGGAAG
CGGAATAA

Upstream 100 bases:

>100_bases
CTACGGATTGAAGGCCACCGTCTCTGGAGTTACTTCTCCGGATGGTGTGACGCTCTCGGTGAAGAAGTAGCCGGGCATCG
GCGCGGGTTACCATCGAGGA

Downstream 100 bases:

>100_bases
GTCCGGCTTACATCGCGTGCAGAAGTTCAATGTCGCCCAGTTTGCCGTCGCCGTTCTTGCCGAACCCGTCCATAACTCCG
CCGAATTCGTCGGCGGGGCC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MEQFDLGFELFPEKRVYTVGELNGAIRKALDGQFTDIRVAGEISNLRLAASGHYYFNLKERDSIVKAVAYRSAARFWKFK
PQDGLAVIARGSLDIYEVRGEYQLQVESLEPQGLGALQLAFEQLKKKLAAEGLFAAERKRPLPRFPRRIGIVTSPRGAAI
ADMIQILSRRFPGLHIRLFPALVQGEGSVEEVCRAIEYFSRTGWADVLIVGRGGGSLEDLWTFNTEAVARAIAACSVPVI
SAVGHETDITIADFVADLRAPTPSAAAEMVVCTRDELLDRIGAARAKAAQGARYRIAMLERRLRLQGIDRALGTLHRRVG
RGLQRIDEQEYRMRERIRIGLDGRERVRRALELRLRRFDVRPRLAADRRRMELARNSALQVMHARLGQDRNRLGQLAATL
SQLSPLRVLERGYAIVSNDGGILKDAAAVPANSQIRVRLAKGGLEAVVTASTEAE

Sequences:

>Translated_455_residues
MEQFDLGFELFPEKRVYTVGELNGAIRKALDGQFTDIRVAGEISNLRLAASGHYYFNLKERDSIVKAVAYRSAARFWKFK
PQDGLAVIARGSLDIYEVRGEYQLQVESLEPQGLGALQLAFEQLKKKLAAEGLFAAERKRPLPRFPRRIGIVTSPRGAAI
ADMIQILSRRFPGLHIRLFPALVQGEGSVEEVCRAIEYFSRTGWADVLIVGRGGGSLEDLWTFNTEAVARAIAACSVPVI
SAVGHETDITIADFVADLRAPTPSAAAEMVVCTRDELLDRIGAARAKAAQGARYRIAMLERRLRLQGIDRALGTLHRRVG
RGLQRIDEQEYRMRERIRIGLDGRERVRRALELRLRRFDVRPRLAADRRRMELARNSALQVMHARLGQDRNRLGQLAATL
SQLSPLRVLERGYAIVSNDGGILKDAAAVPANSQIRVRLAKGGLEAVVTASTEAE
>Mature_455_residues
MEQFDLGFELFPEKRVYTVGELNGAIRKALDGQFTDIRVAGEISNLRLAASGHYYFNLKERDSIVKAVAYRSAARFWKFK
PQDGLAVIARGSLDIYEVRGEYQLQVESLEPQGLGALQLAFEQLKKKLAAEGLFAAERKRPLPRFPRRIGIVTSPRGAAI
ADMIQILSRRFPGLHIRLFPALVQGEGSVEEVCRAIEYFSRTGWADVLIVGRGGGSLEDLWTFNTEAVARAIAACSVPVI
SAVGHETDITIADFVADLRAPTPSAAAEMVVCTRDELLDRIGAARAKAAQGARYRIAMLERRLRLQGIDRALGTLHRRVG
RGLQRIDEQEYRMRERIRIGLDGRERVRRALELRLRRFDVRPRLAADRRRMELARNSALQVMHARLGQDRNRLGQLAATL
SQLSPLRVLERGYAIVSNDGGILKDAAAVPANSQIRVRLAKGGLEAVVTASTEAE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=448, Percent_Identity=40.1785714285714, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50601; Mature: 50601

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFDLGFELFPEKRVYTVGELNGAIRKALDGQFTDIRVAGEISNLRLAASGHYYFNLKE
CCCCCCCCEECCCCCEEEEHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEEEHH
RDSIVKAVAYRSAARFWKFKPQDGLAVIARGSLDIYEVRGEYQLQVESLEPQGLGALQLA
HHHHHHHHHHHHHHHHEECCCCCCEEEEEECCEEEEEECCCEEEEEECCCCCCCHHHHHH
FEQLKKKLAAEGLFAAERKRPLPRFPRRIGIVTSPRGAAIADMIQILSRRFPGLHIRLFP
HHHHHHHHHHCCHHHHHHCCCCCCCHHHCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEH
ALVQGEGSVEEVCRAIEYFSRTGWADVLIVGRGGGSLEDLWTFNTEAVARAIAACSVPVI
HHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCHHH
SAVGHETDITIADFVADLRAPTPSAAAEMVVCTRDELLDRIGAARAKAAQGARYRIAMLE
HHCCCCCCCHHHHHHHHHCCCCCCHHHHEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHH
RRLRLQGIDRALGTLHRRVGRGLQRIDEQEYRMRERIRIGLDGRERVRRALELRLRRFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCC
RPRLAADRRRMELARNSALQVMHARLGQDRNRLGQLAATLSQLSPLRVLERGYAIVSNDG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCEEEECCC
GILKDAAAVPANSQIRVRLAKGGLEAVVTASTEAE
CEECCCCCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MEQFDLGFELFPEKRVYTVGELNGAIRKALDGQFTDIRVAGEISNLRLAASGHYYFNLKE
CCCCCCCCEECCCCCEEEEHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCEEEEEHH
RDSIVKAVAYRSAARFWKFKPQDGLAVIARGSLDIYEVRGEYQLQVESLEPQGLGALQLA
HHHHHHHHHHHHHHHHEECCCCCCEEEEEECCEEEEEECCCEEEEEECCCCCCCHHHHHH
FEQLKKKLAAEGLFAAERKRPLPRFPRRIGIVTSPRGAAIADMIQILSRRFPGLHIRLFP
HHHHHHHHHHCCHHHHHHCCCCCCCHHHCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEH
ALVQGEGSVEEVCRAIEYFSRTGWADVLIVGRGGGSLEDLWTFNTEAVARAIAACSVPVI
HHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCHHH
SAVGHETDITIADFVADLRAPTPSAAAEMVVCTRDELLDRIGAARAKAAQGARYRIAMLE
HHCCCCCCCHHHHHHHHHCCCCCCHHHHEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHH
RRLRLQGIDRALGTLHRRVGRGLQRIDEQEYRMRERIRIGLDGRERVRRALELRLRRFDV
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCC
RPRLAADRRRMELARNSALQVMHARLGQDRNRLGQLAATLSQLSPLRVLERGYAIVSNDG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCEEEECCC
GILKDAAAVPANSQIRVRLAKGGLEAVVTASTEAE
CEECCCCCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA