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The map label for this gene is hemK [C]

Identifier: 116619371

GI number: 116619371

Start: 309711

End: 311270

Strand: Direct

Name: hemK [C]

Synonym: Acid_0229

Alternate gene names: 116619371

Gene position: 309711-311270 (Clockwise)

Preceding gene: 116619370

Following gene: 116619373

Centisome position: 3.11

GC content: 64.94

Gene sequence:

>1560_bases
ATGCGGCGATGCTATCCTCTCCCCATGACACCGACGGACTCACAGCCGCACACCTGGCACCGGATCGCACCGCGACTGGG
CAGTGACGCGGAGTTCGCGGCGGTGCGCGGCATGCTGGCACAATGCGGCTTTACGCAAGAGCGGGTTTTCGAACGCCTGG
GCATTGCCGGAGCCGGCGAGTACAAGCCGGTTTGGCTGGGAGGCAGCAACCTGCCCGAGGCGAAGGATGCGCTGGGTGCC
CTGATCCTGCTGCTAATGGACGGTGACTTTGTGGCTGGCGAAACCCTGGCGCAGCTACTGCCGGTGGGCGCGGTCGAGCA
ACTGGAAGCGCTCCGGCTGATCGGCCGGGATCCGCAAAACCATGAGAGGTGGTTCGGCGGGTGCACCGTATTCCCTACGC
GCGGACTGCTGCTCGCGAGCGATCGGGCTTCGTCGCCGGACGGAGCCAGGCATCCCACAAGCGCAGACATGGTATACCCG
GCCGCTATCGACACTACCGCGGTTTTCATGTCCACGCTTCCCGAGATGCCGTGCGACGCCCTTCTGGACGTGGGCACCGG
CTCGGGAATTGCCGCACTCGATGGCGCCCGTTACGCGCGTCACGCGTGGGGCACGGATATCGCGGCCCGCTCCGTGCAAT
TTGCGGAATTCAACCGGCGCTTGAACGGTATCCAGAACGCCACCATGCTGCAGGGCGACCTCTACGTACCGGTGGAGGGA
TTGACCTTCGACCGAATCGTGGCCCATCCGCCGTACGTGCCGGTGCGGAAGAACGAGTTGATTTTTCGGGATGGCGGCGA
GGACGGAGAACAGATCCTGCGCCGCATTGTCGAAGGCCTCCCGCGATTTCTGCGCCCGGGCGGCAGGTTCTACACCATGG
TCACTGCGGCGGATTGCGAGGGCCAGGCGTTTGAAGATCGCTTGCGGCTCTGGCTGGGACCGGTGGCTGCGGAATTTGAT
CTGGTGCTGGTGGCGCACACGGCGCGGAGCCCGAAAGCCGTGGCTGTGGACTCATTTCTCGGCGGCAACACGTCAGTCGC
GGACATTCGCTACCGCCACGAGATGTGGGAGCGGCGGAAGACCAAGTCCTTGTTCCATGGCAGAGTCCTGGTGCGCCGGC
ATGAGGCACCGCGCCCGGCGTTTACGCAGCGCGTGCTGAGGGGACAGGGCTTCACGCAAGCGCATGTGGAATGGTTGCTG
GAATGGGGCACGGCATTCCACGATGCCGCGTCGCAGGAGCAACTCATGGACTTGCGGCCCCGCCTATCGCCGCATGCCGA
ATTGGACGTGATCCACCACGTCCGTAACGGCCGGTTCGCACCCGAGGGATTTTCACTGCGTTGCAGGCGCCCCTTCGATG
CGGAGCGCGTTCTGCCGCCGTGGCTGGCACAGATCATTGCGCAGTGCGATGGGCGGACCAGCTGGCAAGGCCAACTGGAG
AATGCCCGGAACGCGGGGCTGGTCTCGCGGGAGTTGACGGCCGCGGAGTTCCTGAGCGTGCTTGAGCGCCTGGTTTCAAA
CGCCCTGCTCTGGGTTGCGGAAAGGCCGCTTCCCGAGTAG

Upstream 100 bases:

>100_bases
ACCGGCCGGCGAGTTCCTGGCGATCCTGGAGCCCCTGGTCTCTAACGGTCTCCTGTGGATCGCGGAAAAGTCCCTTCCCG
GGTTGTCCGGCTGACGTCTG

Downstream 100 bases:

>100_bases
CGATCGCAGACTAAAGTCAGGCTATCAGCAAACCCCTTTCGGCGAGCAATTTCAGATTTTCCTGAATCCCCCGCGCCAAT
TCCGCCTCGGGCAGGTGGGA

Product: methyltransferase small

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MRRCYPLPMTPTDSQPHTWHRIAPRLGSDAEFAAVRGMLAQCGFTQERVFERLGIAGAGEYKPVWLGGSNLPEAKDALGA
LILLLMDGDFVAGETLAQLLPVGAVEQLEALRLIGRDPQNHERWFGGCTVFPTRGLLLASDRASSPDGARHPTSADMVYP
AAIDTTAVFMSTLPEMPCDALLDVGTGSGIAALDGARYARHAWGTDIAARSVQFAEFNRRLNGIQNATMLQGDLYVPVEG
LTFDRIVAHPPYVPVRKNELIFRDGGEDGEQILRRIVEGLPRFLRPGGRFYTMVTAADCEGQAFEDRLRLWLGPVAAEFD
LVLVAHTARSPKAVAVDSFLGGNTSVADIRYRHEMWERRKTKSLFHGRVLVRRHEAPRPAFTQRVLRGQGFTQAHVEWLL
EWGTAFHDAASQEQLMDLRPRLSPHAELDVIHHVRNGRFAPEGFSLRCRRPFDAERVLPPWLAQIIAQCDGRTSWQGQLE
NARNAGLVSRELTAAEFLSVLERLVSNALLWVAERPLPE

Sequences:

>Translated_519_residues
MRRCYPLPMTPTDSQPHTWHRIAPRLGSDAEFAAVRGMLAQCGFTQERVFERLGIAGAGEYKPVWLGGSNLPEAKDALGA
LILLLMDGDFVAGETLAQLLPVGAVEQLEALRLIGRDPQNHERWFGGCTVFPTRGLLLASDRASSPDGARHPTSADMVYP
AAIDTTAVFMSTLPEMPCDALLDVGTGSGIAALDGARYARHAWGTDIAARSVQFAEFNRRLNGIQNATMLQGDLYVPVEG
LTFDRIVAHPPYVPVRKNELIFRDGGEDGEQILRRIVEGLPRFLRPGGRFYTMVTAADCEGQAFEDRLRLWLGPVAAEFD
LVLVAHTARSPKAVAVDSFLGGNTSVADIRYRHEMWERRKTKSLFHGRVLVRRHEAPRPAFTQRVLRGQGFTQAHVEWLL
EWGTAFHDAASQEQLMDLRPRLSPHAELDVIHHVRNGRFAPEGFSLRCRRPFDAERVLPPWLAQIIAQCDGRTSWQGQLE
NARNAGLVSRELTAAEFLSVLERLVSNALLWVAERPLPE
>Mature_519_residues
MRRCYPLPMTPTDSQPHTWHRIAPRLGSDAEFAAVRGMLAQCGFTQERVFERLGIAGAGEYKPVWLGGSNLPEAKDALGA
LILLLMDGDFVAGETLAQLLPVGAVEQLEALRLIGRDPQNHERWFGGCTVFPTRGLLLASDRASSPDGARHPTSADMVYP
AAIDTTAVFMSTLPEMPCDALLDVGTGSGIAALDGARYARHAWGTDIAARSVQFAEFNRRLNGIQNATMLQGDLYVPVEG
LTFDRIVAHPPYVPVRKNELIFRDGGEDGEQILRRIVEGLPRFLRPGGRFYTMVTAADCEGQAFEDRLRLWLGPVAAEFD
LVLVAHTARSPKAVAVDSFLGGNTSVADIRYRHEMWERRKTKSLFHGRVLVRRHEAPRPAFTQRVLRGQGFTQAHVEWLL
EWGTAFHDAASQEQLMDLRPRLSPHAELDVIHHVRNGRFAPEGFSLRCRRPFDAERVLPPWLAQIIAQCDGRTSWQGQLE
NARNAGLVSRELTAAEFLSVLERLVSNALLWVAERPLPE

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 57670; Mature: 57670

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRCYPLPMTPTDSQPHTWHRIAPRLGSDAEFAAVRGMLAQCGFTQERVFERLGIAGAGE
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
YKPVWLGGSNLPEAKDALGALILLLMDGDFVAGETLAQLLPVGAVEQLEALRLIGRDPQN
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
HERWFGGCTVFPTRGLLLASDRASSPDGARHPTSADMVYPAAIDTTAVFMSTLPEMPCDA
CHHHCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCHHH
LLDVGTGSGIAALDGARYARHAWGTDIAARSVQFAEFNRRLNGIQNATMLQGDLYVPVEG
HHCCCCCCCEEHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECC
LTFDRIVAHPPYVPVRKNELIFRDGGEDGEQILRRIVEGLPRFLRPGGRFYTMVTAADCE
CCHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
GQAFEDRLRLWLGPVAAEFDLVLVAHTARSPKAVAVDSFLGGNTSVADIRYRHEMWERRK
CHHHHHHHHHHHCCHHHCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
TKSLFHGRVLVRRHEAPRPAFTQRVLRGQGFTQAHVEWLLEWGTAFHDAASQEQLMDLRP
HHHHHHHHHEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
RLSPHAELDVIHHVRNGRFAPEGFSLRCRRPFDAERVLPPWLAQIIAQCDGRTSWQGQLE
CCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHC
NARNAGLVSRELTAAEFLSVLERLVSNALLWVAERPLPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEHCCCCCCC
>Mature Secondary Structure
MRRCYPLPMTPTDSQPHTWHRIAPRLGSDAEFAAVRGMLAQCGFTQERVFERLGIAGAGE
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
YKPVWLGGSNLPEAKDALGALILLLMDGDFVAGETLAQLLPVGAVEQLEALRLIGRDPQN
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
HERWFGGCTVFPTRGLLLASDRASSPDGARHPTSADMVYPAAIDTTAVFMSTLPEMPCDA
CHHHCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCHHH
LLDVGTGSGIAALDGARYARHAWGTDIAARSVQFAEFNRRLNGIQNATMLQGDLYVPVEG
HHCCCCCCCEEHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECC
LTFDRIVAHPPYVPVRKNELIFRDGGEDGEQILRRIVEGLPRFLRPGGRFYTMVTAADCE
CCHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
GQAFEDRLRLWLGPVAAEFDLVLVAHTARSPKAVAVDSFLGGNTSVADIRYRHEMWERRK
CHHHHHHHHHHHCCHHHCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
TKSLFHGRVLVRRHEAPRPAFTQRVLRGQGFTQAHVEWLLEWGTAFHDAASQEQLMDLRP
HHHHHHHHHEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
RLSPHAELDVIHHVRNGRFAPEGFSLRCRRPFDAERVLPPWLAQIIAQCDGRTSWQGQLE
CCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHC
NARNAGLVSRELTAAEFLSVLERLVSNALLWVAERPLPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]