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The map label for this gene is atpA [H]

Identifier: 116517209

GI number: 116517209

Start: 1352312

End: 1353817

Strand: Reverse

Name: atpA [H]

Synonym: SPD_1337

Alternate gene names: 116517209

Gene position: 1353817-1352312 (Counterclockwise)

Preceding gene: 116516143

Following gene: 116515905

Centisome position: 66.17

GC content: 44.36

Gene sequence:

>1506_bases
TTGGCAATTAACGCACAAGAAATCAGCGCTTTAATTAAGCAACAAATTGAAAATTTCAAACCCAATTTTGATGTGACTGA
AACAGGTGTTGTAACCTATATCGGGGACGGTATCGCGCGTGCTCACGGCCTTGAAAATGTCATGAGTGGAGAGTTGTTGA
ATTTTGAAAACGGCTCTTATGGTATGGCTCAAAACTTGGAGTCAACAGACGTTGGTATTATCATCCTAGGTGACTTTACA
GATATCCGTGAAGGCGATACAATCCGCCGTACAGGGAAAATCATGGAAGTCCCTGTAGGTGAAAGTCTGATTGGTCGTGT
TGTGGATCCGCTTGGTCGTCCAGTTGACGGTCTTGGAGAAATCCACACTGATAAAACTCGTCCAGTAGAAGCACCAGCTC
CTGGTGTTATGCAACGTAAGTCTGTTTCAGAACCATTGCAAACTGGTTTGAAAGCTATTGACGCCCTTGTACCGATTGGT
CGTGGTCAACGTGAGTTGATTATCGGTGACCGTCAGACAGGGAAAACAACCATTGCGATTGATACAATCTTGAACCAAAA
AGATCAAGATATGATCTGTATCTACGTCGCGATTGGACAAAAAGAATCAACAGTTCGTACGCAAGTAGAAACACTTCGTC
AGTACGGTGCCTTGGACTACACAATCGTTGTGACAGCCTCTGCTTCACAACCATCTCCATTGCTCTTCCTAGCTCCTTAT
GCTGGGGTTGCTATGGCGGAAGAATTTATGTATCAAGGTAAGCATGTTTTGATTGTATACGATGATCTATCAAAACAAGC
GGTAGCTTATCGTGAACTGTTGCTCTTGCTTCGTCGTCCTCCAGGTCGTGAAGCCTTCCCAGGGGATGTTTTCTATCTCC
ACAGCCGTTTGCTTGAGCGCTCAGCTAAAGTTTCTGATGAACTTGGTGGTGGATCAATTACAGCCCTACCATTTATCGAG
ACACAAGCAGGAGATATCTCAGCCTATATCGCAACCAACGTGATTTCTATCACTGATGGACAAATCTTCCTTGGCGATGG
CCTCTTCAATGCAGGTATTCGTCCAGCCATCGATGCGGGTTCATCTGTATCTCGTGTAGGTGGTTCTGCACAAATCAAAG
CCATGAAGAAGGTTGCTGGTACACTTCGTATCGACCTTGCTTCATACCGTGAGTTGGAAGCCTTTACTAAGTTTGGTTCT
GACTTGGACGCAGCAACACAGGCTAAGTTGAACCGTGGACGTCGTACCGTTGAGGTCTTGAAACAACCTGTTCACAAACC
ATTACCTGTTGAGAAACAAGTAACCATTCTTTATGCTTTGACACATGGTTTCTTGGATACTGTTCCAGTAGATGATATTG
TTCGTTTCGAGGAAGAGTTCCATGCCTTCTTTGATGCTCAACATCCAGAGATTTTGGAAACCATTCGTGATACAAAAGAC
TTGCCAGAAGAAGCAGTCTTGGATGCTGCGATTACAGAGTTTCTCAATCAATCTAGCTTCCAATAA

Upstream 100 bases:

>100_bases
GTGGTTTTGTCATTTTTGCCAATCACAAGACAATTGATGTGAGTATTAAACAACAACTTAAAGTTGTTAAAGAAAATTTG
AAATAGAAAGTGGTGTTCTT

Downstream 100 bases:

>100_bases
GAATAGAGGTGTCAGATGGCAGTATCTCTAAATGATATTAAAACAAAAATCGCCTCAACAAAAAATACGAGTCAAATCAC
TAATGCCATGCAAATGGTAT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFT
DIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELLLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGS
DLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
LPEEAVLDAAITEFLNQSSFQ

Sequences:

>Translated_501_residues
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFT
DIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELLLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIE
TQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGS
DLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
LPEEAVLDAAITEFLNQSSFQ
>Mature_500_residues
AINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTD
IREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGR
GQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYA
GVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELLLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIET
QAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSD
LDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKDL
PEEAVLDAAITEFLNQSSFQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=499, Percent_Identity=57.314629258517, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI4757810, Length=499, Percent_Identity=57.314629258517, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI19913426, Length=305, Percent_Identity=28.8524590163934, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI19913428, Length=301, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI32189394, Length=375, Percent_Identity=24, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1790172, Length=495, Percent_Identity=53.3333333333333, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=33.8235294117647, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790170, Length=383, Percent_Identity=24.8041775456919, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=56.5737051792829, Blast_Score=567, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=56.5737051792829, Blast_Score=566, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=52.5896414342629, Blast_Score=510, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17510931, Length=384, Percent_Identity=27.0833333333333, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=27.8523489932886, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=429, Percent_Identity=22.6107226107226, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=37.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565854, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=499, Percent_Identity=54.7094188376754, Blast_Score=548, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6319603, Length=305, Percent_Identity=28.8524590163934, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=372, Percent_Identity=24.1935483870968, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=55.8415841584158, Blast_Score=555, Evalue=1e-158,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=28.2392026578073, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=28.2392026578073, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=28.2392026578073, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24638766, Length=409, Percent_Identity=24.6943765281174, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574560, Length=391, Percent_Identity=24.8081841432225, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54672; Mature: 54541

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSY
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCC
GMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGE
HHHCCCCCCCEEEEEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCC
IHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
EHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELLLLLRRPPGREAFPGDVFYLHSRLLER
CHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAG
HHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCCCCCCCCCCC
SSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVL
CCHHHCCCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
HHHCCCCCCCCHHEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
LPEEAVLDAAITEFLNQSSFQ
CCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSY
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEECCCCCC
GMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGE
HHHCCCCCCCEEEEEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCCC
IHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPY
EHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCC
AGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELLLLLRRPPGREAFPGDVFYLHSRLLER
CHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
SAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAG
HHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCCCCCCCCCCC
SSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVL
CCHHHCCCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHH
KQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKD
HHHCCCCCCCCHHEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
LPEEAVLDAAITEFLNQSSFQ
CCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA