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The map label for this gene is argS

Identifier: 116516539

GI number: 116516539

Start: 1876583

End: 1878274

Strand: Direct

Name: argS

Synonym: SPD_1905

Alternate gene names: 116516539

Gene position: 1876583-1878274 (Clockwise)

Preceding gene: 116516118

Following gene: 116515391

Centisome position: 91.71

GC content: 42.38

Gene sequence:

>1692_bases
ATGAATACAAAAGAATTGATTGCTAGCGAATTATCTAGCATCATTGATAGCCTGGACCAAGAGGCTATTTTAAAGTTACT
GGAAACCCCTAAAAACTCAGAAATGGGAGACATTGCTTTCCCTGCTTTTTCTCTTGCAAAAGTCGAACGTAAAGCACCAC
AAATGATTGCGGCTGAACTGGCTGAAAAAATGAACAGCCAAGCCTTTGAAAAAGTTGTCGCAACAGGACCTTACGTTAAC
TTTTTCCTTGATAAATCTGCCATTTCTGCTCAAGTATTGCAAGCTGTTACCACTGAAAAAGAACACTATGCTGACCAAAA
TATTGGCAAACAAGAAAATGTTGTTATCGACATGTCTAGTCCGAATATCGCTAAACCATTTTCTATTGGCCACCTGCGTT
CAACTGTTATCGGAGATAGCTTGTCACATATTTTCCAAAAAATCGGTTATCAAACGGTCAAGGTCAACCATTTGGGAGAC
TGGGGTAAACAATTTGGGATGTTGATTGTTGCCTACAAAAAATGGGGCGACGAAGAAGCTGTAAAAGCTCATCCAATCGA
TGAACTCCTTAAACTCTATGTCCGCATCAACGCTGAAGCTGAAAATGACCCTAGCTTGGATGAAGAAGCGCGCGAATGGT
TCCGTAAACTTGAAAATGGAGATGAGGAAGCTCTCGCTCTTTGGCAATGGTTCCGCGATGAAAGTTTAGTGGAATTTAAC
CGCCTTTACAATGAATTGAAGGTTGAATTTGACAGCTATAACGGAGAAGCCTTCTACAATGATAAGATGGATGCAGTTGT
AGACATTCTTTCTGAAAAAGGACTACTTCTTGAATCAGAAGGTGCCCAAGTTGTGAATCTTGAGAAATATGGAATTGAAC
ATCCAGCCCTCATCAAGAAGTCTGATGGTGCAACTCTCTATATCACACGTGACTTGGCTGCAGCCCTCTACCGTAAAAAT
GAATACCAATTTGCTAAATCTATCTACGTCGTTGGTCAAGAGCAATCTGCCCACTTTAAACAACTCAAAGCTGTCTTGCA
AGAGATGGGCTACGATTGGAGTGACGACATTACCCACGTTCCTTTTGGTCTGGTTACAAAAGAAGGGAAGAAGCTCTCTA
CTCGTAAAGGGAATGTCATCTTGCTAGAGCCTACTGTTGCAGAGGCTGTTAGCCGTGCCAAGGTCCAAATCGAGGCTAAA
AATCCTGAACTAGAAAACAAAGACCAAGTAGCACATGCTGTTGGGGTTGGAGCCATTAAATTCTATGACCTCAAAACTGA
CCGTACAAATGGATACGACTTCGACCTAGAAGCTATGGTATCCTTCGAGGGTGAAACTGGACCTTACGTTCAATATGCCT
ACGCTCGTATCCAATCTATCTTACGCAAAGCCGATTTCAAACCAGAAACAGCTGGCAACTATAGCTTGAATGATACTGAA
AGCTGGGAAATCATTAAACTCATTCAAGACTTCCCACGTATTATCAACCGTGCGGCAGATAACTTTGAACCTTCTATCAT
TGCTAAATTTGCAATTAGCCTGGCTCAATCCTTTAACAAATACTATGCACATACACGTATCTTGGATGAAAGCCCAGAAC
GCGACAGCCGTCTAGCCCTCAGCTACGCAACCGCAGTCGTTCTCAAAGAAGCCCTTCGCTTGCTTGGAGTAGAAGCGCCA
GAGAAGATGTAA

Upstream 100 bases:

>100_bases
ATAACCATATTATACCAAAAAAACAGGAGATTTCAAAAATTTTTTCTTCTTTCTTTAAAATTGTGATAAAATAGTAGAAA
AGTCCAAAAAGGAGCTCTTA

Downstream 100 bases:

>100_bases
ATCGCCAAAGTTACTTGATTGCAAAGCAATCTAAGTAACTAACGCCAAATCCTATTCGGACTTTGGCTAGGCGCTTCACT
AGTTTTAGGACATAAATATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVN
FFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKN
EYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAK
NPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAP
EKM

Sequences:

>Translated_563_residues
MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVN
FFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKN
EYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAK
NPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAP
EKM
>Mature_563_residues
MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVN
FFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKN
EYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAK
NPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAP
EKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI197100773, Length=584, Percent_Identity=33.9041095890411, Blast_Score=330, Evalue=3e-90,
Organism=Homo sapiens, GI15149476, Length=556, Percent_Identity=29.3165467625899, Blast_Score=237, Evalue=2e-62,
Organism=Escherichia coli, GI1788184, Length=538, Percent_Identity=34.0148698884758, Blast_Score=289, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI71985061, Length=574, Percent_Identity=31.184668989547, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI71985068, Length=551, Percent_Identity=31.0344827586207, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17532153, Length=497, Percent_Identity=27.1629778672032, Blast_Score=176, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6320548, Length=578, Percent_Identity=35.9861591695502, Blast_Score=379, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321883, Length=568, Percent_Identity=34.1549295774648, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI18859963, Length=545, Percent_Identity=31.3761467889908, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI28571570, Length=469, Percent_Identity=31.7697228144989, Blast_Score=224, Evalue=9e-59,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_STRP2 (Q04I94)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817294.1
- ProteinModelPortal:   Q04I94
- SMR:   Q04I94
- STRING:   Q04I94
- EnsemblBacteria:   EBSTRT00000019977
- GeneID:   4441042
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1905
- eggNOG:   COG0018
- GeneTree:   EBGT00050000028153
- HOGENOM:   HBG695395
- OMA:   AYKKWGN
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63458; Mature: 63458

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAEL
CCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
AEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSS
HHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
PNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGDWGKQFGMLIVAYKKWGDEEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCEEEEEEECCCCCCC
VKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
CCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKK
HHHHHHEEEEECCCCCEEECCHHHHHHHHHHCCCCEEECCCCCEEEHHHHCCCCCCEEEE
SDGATLYITRDLAAALYRKNEYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHV
CCCCEEEEEHHHHHHHHHCCHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
PFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAKNPELENKDQVAHAVGVGAIK
CCCEEECCCCEEECCCCCEEEECCHHHHHHHHCEEEEEECCCCCCCHHHHHHHHCCCEEE
FYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLAL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYATAVVLKEALRLLGVEAPEKM
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAEL
CCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
AEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSS
HHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
PNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGDWGKQFGMLIVAYKKWGDEEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCEEEEEEECCCCCCC
VKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
CCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKK
HHHHHHEEEEECCCCCEEECCHHHHHHHHHHCCCCEEECCCCCEEEHHHHCCCCCCEEEE
SDGATLYITRDLAAALYRKNEYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHV
CCCCEEEEEHHHHHHHHHCCHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
PFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAKNPELENKDQVAHAVGVGAIK
CCCEEECCCCEEECCCCCEEEECCHHHHHHHHCEEEEEECCCCCCCHHHHHHHHCCCEEE
FYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLAL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYATAVVLKEALRLLGVEAPEKM
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA