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The map label for this gene is msmR [H]

Identifier: 116516533

GI number: 116516533

Start: 1695670

End: 1696530

Strand: Direct

Name: msmR [H]

Synonym: SPD_1679

Alternate gene names: 116516533

Gene position: 1695670-1696530 (Clockwise)

Preceding gene: 116515994

Following gene: 116515717

Centisome position: 82.87

GC content: 36.7

Gene sequence:

>861_bases
ATGCTAGTTTTTTCAGAATACCAGACTGGAACAATTGACCTTGCCCTAAGCTTTTATGGATATGAGGAATGCACACCTAA
TTACTCTTTTGGTCCAGCCATTCGTGATACATACGTCCTACATTACATTAGTAAAGGACAAGGAAAATTTCATTACAAGG
GTAAAATTGTTGATTTAAAAGAAGGAGATTTCTTTCTATTAAAACCAGAGGAACTAACCTTTTATCAAGCAGATAGTAAA
GAACCTTGGGCCTACTACTGGTTAGGAATCACTGGAGGGAAATCCCCTGATTATTTTGCTCTTTCTCAAATTTCTGATCA
ATCCTATCTCATCCAATCTGAAACTTGTCATACCCAGACTACTGCAAAACTCATCTCAGACATTGTCCGCTTCGCTCAGA
TTACAAAATCAAGTGAATTAGCTCAACTCCATATCATGGGACAACTTCATGAACTGATGTTTCATCTGGGAACTATTGCT
CCCAATCAGAAAAAAAAGAATATTTCATCAACCCACCAACTCTATCTTGAATGCAAACGATTAATTGATAGCCACTATCC
TCAATCACTTACAATTCAAGATTTAGCAAAAGAACTATCCGTTCACAGAAGCTACTTATCAAGCGTATTCAAAGAATTTA
ATACCTTATCACCCAAAGAATACCTACTCTACGTTCGAATGCACCGAGCTAGACAACTTCTCGAAAATACCCAAGAGTCC
ATCAAGGTAATTGCATACTCGGTAGGTTTTTCAGATCCACTCCATTTTTCGAAAGCTTATAAACAATACTTTAATCAGTC
TCCAAGTCATACAAGAAAAGAATACTCTCAATACCAACTAGTGAGAAAGGCAACATTATGA

Upstream 100 bases:

>100_bases
ACCTCATCACTTTATTGATTATATTTTATCACCTGAAATCGCTTTCCAAAATAGAAAAATGTCTCAAGAATATGGTAAAA
TGTTAGGTAGGAGGTAGCAC

Downstream 100 bases:

>100_bases
AATCCTACCAAGCTGTCTACCAAATCCTATCTAAAGAAACCGACTATATCAGCGGAGAAAAAATCGCAGAAAAACTATCC
CTAAGCCGAACATCAATTTG

Product: msm operon regulatory protein MsmR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYISKGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSK
EPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
IKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYSQYQLVRKATL

Sequences:

>Translated_286_residues
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYISKGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSK
EPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
IKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYSQYQLVRKATL
>Mature_286_residues
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYISKGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSK
EPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
IKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYSQYQLVRKATL

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510985, Length=252, Percent_Identity=24.6031746031746, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33191; Mature: 33191

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYISKGQGKFHYKGKIVDLK
CEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHHHEEEEECCCCEEEECCEEEEEC
EGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQT
CCCEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCEEEECCCCCHHH
TAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIAPNQKKKNISSTHQLYLECKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHH
LIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYSQYQLVRKATL
HEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYISKGQGKFHYKGKIVDLK
CEEECCCCCCEEEEEEEECCHHHCCCCCCCCCCHHHHHHEEEEECCCCEEEECCEEEEEC
EGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALSQISDQSYLIQSETCHTQT
CCCEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCEEEECCCCCHHH
TAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIAPNQKKKNISSTHQLYLECKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHH
LIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSPKEYLLYVRMHRARQLLENTQES
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
IKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYSQYQLVRKATL
HEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]