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The map label for this gene is galE-1 [H]

Identifier: 116516336

GI number: 116516336

Start: 1448258

End: 1449277

Strand: Reverse

Name: galE-1 [H]

Synonym: SPD_1432

Alternate gene names: 116516336

Gene position: 1449277-1448258 (Counterclockwise)

Preceding gene: 116516255

Following gene: 116515490

Centisome position: 70.83

GC content: 43.43

Gene sequence:

>1020_bases
ATGCAAGAAAAGATTTTGGTAACTGGTGGTGCCGGTTTTATTGGAACCCACACTGTTATTGAATTGATCCAAGCAGGTCA
TCAAGTTGTTGTGGTGGATAATCTTGTCAATAGCAATCGTAAGAGTTTAGAAGTTGTTGAAAGAATCACAGGAGTTGAGA
TTCCTTTCTATGAGGCAGATATTCGTGACACAGATACCCTCAGAGATATTTTCAAGCAGGAAGAACCGACTGGTGTCATT
CACTTTGCTGGTTTGAAGGCTGTTGGCGAATCAACACGTATCCCTCTTGCCTACTATGACAACAATATCGCTGGAACTGT
CAGCCTTTTGAAAGCCATGGAAGAAAACAACTGTAAAAACATCATCTTCAGTTCTTCTGCGACAGTTTACGGGGATCCGC
ACACAGTGCCCATCTTGGAAGATTTCCCACTTTCAGTGACCAACCCATACGGTCGTACTAAGCTCATGCTAGAGGAAATT
TTGACTGATATTTACAAAGCAGACTCAGAATGGAATGTTGTCTTGCTTCGTTACTTTAACCCAATCGGAGCCCATGAGAG
TGGTGATTTGGGAGAAAATCCAAACGGTATTCCAAACAATCTCTTGCCATATGTGACTCAAGTAGCCGTTGGAAAATTAG
AGCAAGTGCAAGTGTTTGGAGACGATTACGATACGGAAGATGGAACAGGTGTTCGTGACTATATCCACGTTGTCGATTTG
GCTAAGGGTCACGTTGCAGCTTTGAAAAAAATCCAAAAAGGTTCAGGACTAAACGTTTATAACCTTGGAACTGGTAAAGG
TTACTCAGTTCTTGAAATTATCCAAAACATGGAAAAAGCGGTGGGATGTCCTATTCCTTACCGCATCGTAGAACGTCGCC
CAGGTGATATCGCTGCCTGCTACTCAGACCCAGCAAAGGCTAAAGCAGAACTCGGTTGGGAAGCAGAACTCGACATCACC
CAAATGTGTGAAGACGCATGGCGTTGGCAGAGCAAGCATCCAAATGGATTTGAAGACTAA

Upstream 100 bases:

>100_bases
ATTTTACTGAAATTTTATCAGGTAGTTTAGGATGGCAAATGACATTCCCTGTCAAAAATGGTAAAATAAGAAAAAATAAT
CTGAGAATCGAGGAAAAAAG

Downstream 100 bases:

>100_bases
GATGATGATTTCAATCATCGTCCCTTGTTTAAACGAAGAGGAAGTACTTCCTCTTTTTTATCAGGCTCTGGAAGCTTTAC
TTCCAGATTTGGAAACAGAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVI
HFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGCPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDIT
QMCEDAWRWQSKHPNGFED

Sequences:

>Translated_339_residues
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVI
HFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGCPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDIT
QMCEDAWRWQSKHPNGFED
>Mature_339_residues
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVI
HFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGCPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDIT
QMCEDAWRWQSKHPNGFED

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=57.5581395348837, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=57.5581395348837, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=57.5581395348837, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=25.1798561151079, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI42516563, Length=318, Percent_Identity=25.7861635220126, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=53.1157270029674, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=28.4431137724551, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788353, Length=346, Percent_Identity=29.4797687861272, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=52.0348837209302, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=51.7341040462428, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17568069, Length=338, Percent_Identity=24.5562130177515, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=53.3527696793003, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=53.4883720930233, Blast_Score=390, Evalue=1e-109,
Organism=Drosophila melanogaster, GI21356223, Length=323, Percent_Identity=24.1486068111455, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37426; Mature: 37426

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEAD
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECHHCCCHHHHHHHHHHHCCCCCEEECC
IRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKN
CCCHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCE
IIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEILTDIYKADSEWNVVLLRYFN
EEEECCEEEECCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
PIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGCPIPYRIVERRPGDIAAC
CCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEE
YSDPAKAKAELGWEAELDITQMCEDAWRWQSKHPNGFED
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLEVVERITGVEIPFYEAD
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECHHCCCHHHHHHHHHHHCCCCCEEECC
IRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNNIAGTVSLLKAMEENNCKN
CCCHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCE
IIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEILTDIYKADSEWNVVLLRYFN
EEEECCEEEECCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECC
PIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQVFGDDYDTEDGTGVRDYIHVVDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
AKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQNMEKAVGCPIPYRIVERRPGDIAAC
CCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEE
YSDPAKAKAELGWEAELDITQMCEDAWRWQSKHPNGFED
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]