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The map label for this gene is hslO

Identifier: 116515969

GI number: 116515969

Start: 1992975

End: 1993847

Strand: Direct

Name: hslO

Synonym: SPD_2015

Alternate gene names: 116515969

Gene position: 1992975-1993847 (Clockwise)

Preceding gene: 116516488

Following gene: 116516462

Centisome position: 97.4

GC content: 45.36

Gene sequence:

>873_bases
ATGGATAAAATTATTAAAACTATATCAGAAAGCGGAGCCTTTCGTGCTTTTGTCCTTGATAGCACTGAAACCGTCCGCAC
TGCTCAAGAAAAACATCAAACCCAAGCTAGCTCAACTGTAGCGCTTGGTCGAACTCTTATCGCCAGCCAGATTCTCGCAG
CCAATGAAAAAGGAAATACCAAACTTACAGTTAAGGTGTTGGGATCTAGCTCTCTAGGTGCTATTATCACCGTCGCTGAT
ACCAAGGGGAACGTCAAAGGCTATGTTCAAAATCCTGGTGTTGACATCAAAAAGACTGCGACTGGTGAAGTCCTAGTCGG
ACCTTTTGTTGGAAATGGTCAATTCCTCGTTATCACAGACTACGGTACTGGAAATCCTTACAACTCTATAACTCCCCTCA
TCTCTGGAGAAATCGGTGAAGACCTTGCCTTTTACCTTACTGAAAGCCAACAAACGCCTTCAGCGGTCGGCCTCAATGTC
CTTTTGGACGAGGAAGACAAGGTCAAGGTTGCAGGTGGTTTCCTAGTTCAAGTCTTGCCAGGAGCCAAGAAAGAAGAGAT
TGCTCGCTTTGAAAAACGCATCCAAGAAATGCCAGCTATCTCTACTCTTCTCGAAAGCGACGACCATATCGAAGCCCTCC
TCAAGGCTATCTACGGGGACGAAGCCTACAAGCGTCTTTCTGAAGAAGAAATCCGTTTCCAATGTGACTGTAGCCATGAA
CGCTTTATGAACGCTCTTGCCAGCCTTCCAAGCTCAGACTTACAGGAAATGAAAGAGGAAGACCACGGGGCAGAAATCAC
TTGTCAATTCTGCCAAACTACTTACAACTTTGATGAAAAGGACCTGGAGGAACTCATTCGTGACAAATCTTAA

Upstream 100 bases:

>100_bases
TTTCTCTTTTTATTTTCATGCTGATTTCCTGGTCCATTATCCTGAAAATCAGTAAACACACGGCTCCCCCTTTGGGCATT
TTTATGCTAAAATAGTAGCT

Downstream 100 bases:

>100_bases
TACACCTTTTATGATTGGCAATATTGAGATTCCCAATCGTACCGTTTTAGCGCCTATGGCTGGCGTGACCAACTCAGCCT
TTCGTACCATCGCAAAAGAG

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVAD
TKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHE
RFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS

Sequences:

>Translated_290_residues
MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVAD
TKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHE
RFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
>Mature_290_residues
MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVAD
TKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHE
RFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=296, Percent_Identity=23.6486486486486, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_STRP2 (Q04HY8)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817400.1
- ProteinModelPortal:   Q04HY8
- SMR:   Q04HY8
- STRING:   Q04HY8
- PhosSite:   Q04HY8
- EnsemblBacteria:   EBSTRT00000020344
- GeneID:   4441411
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_2015
- eggNOG:   COG1281
- GeneTree:   EBGT00050000027836
- HOGENOM:   HBG286231
- OMA:   GYIQNPG
- ProtClustDB:   PRK00114
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31663; Mature: 31663

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNT
CCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITD
EEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCEEECCCCCEEEEEEECCCEEEEEEE
YGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDEEDKVKVAGGFLVQVLP
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHCEEEEECCCCCEEEECCEEEEECC
GAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHE
CCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCHHHHHCCHHHEEEEECCCHH
RFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
HHHHHHHHCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNT
CCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITD
EEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCEEECCCCCEEEEEEECCCEEEEEEE
YGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDEEDKVKVAGGFLVQVLP
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHCEEEEECCCCCEEEECCEEEEECC
GAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHE
CCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCHHHHHCCHHHEEEEECCCHH
RFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
HHHHHHHHCCCHHHHHHHHHCCCCEEEEEEHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA