Click here to switch to the map view.

The map label for this gene is xpt

Identifier: 116515812

GI number: 116515812

Start: 1642851

End: 1643432

Strand: Direct

Name: xpt

Synonym: SPD_1628

Alternate gene names: 116515812

Gene position: 1642851-1643432 (Clockwise)

Preceding gene: 116516049

Following gene: 116516978

Centisome position: 80.29

GC content: 44.16

Gene sequence:

>582_bases
ATGAAATTATTAGAAGAGCGCATCCTCAAGGATGGGCATATCTTGGATGATAACATCCTCAAGGTAGATTCCTTTTTAAC
CCACCAAGTTGACTTTAGCTTGATGCGAGAGATTGGTAAGGTTTTTGCGGAAAAATTTGCTGCTACTGGCATTACCAAGG
TCGTAACCATTGAAGCGTCGGGTATTGCCCCAGCCGTTTTTACAGCTGAAGCCTTAAACGTTCCCATGATTTTCGCCAAA
AAAGCTAAGAACATCACCATGAACGAAGGCATCTTAACTGCTCAAGTCTACTCCTTTACCAAGCAGGTGACCAGCACTGT
TTCTATCGCTGGAAAATTCCTCTCACCAGAGGACAAGGTTTTGATTATCGACGATTTCCTTGCTAATGGCCAAGCTGCTA
AAGGCTTGATTCAAATCATCGAACAGGCCGGTGCCACAGTCCAAGCTATCGGTATCGTGATTGAGAAATCCTTCCAAGAT
GGTCGTGATTTGCTTGAAAAAGCAGGCTACCCTGTCCTATCACTTGCTCGCTTGGATCGTTTTGAAAATGGTCAGGTCGT
ATTTAAGGAGGCAGATCTCTAA

Upstream 100 bases:

>100_bases
GCTCGTAATAGTTTTATCAAATATATAGTATTAGCAAAAGGGATCACTATAGAAATATTTAAACAACAAGTAAATTAACT
TTTAGACTTTAGGAGGTCTT

Downstream 100 bases:

>100_bases
TGCAAACTCAAGAAAAACACTCGCAAGCAGCCGTTCTGGGCTTGCAGCACTTACTAGCCATGTACTCAGGATCTATCCTG
GTTCCCATCATGATTGCGAC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAK
KAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL

Sequences:

>Translated_193_residues
MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAK
KAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL
>Mature_193_residues
MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAK
KAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_STRP2 (Q04IV9)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817079.1
- ProteinModelPortal:   Q04IV9
- SMR:   Q04IV9
- STRING:   Q04IV9
- EnsemblBacteria:   EBSTRT00000020184
- GeneID:   4442859
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1628
- eggNOG:   COG0503
- GeneTree:   EBGT00050000026781
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21044; Mature: 21044

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEAS
CCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKV
CCCCHHEEHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDR
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHCHHHHHHHHHHCCCCEEHHHHHHC
FENGQVVFKEADL
CCCCCEEEEECCC
>Mature Secondary Structure
MKLLEERILKDGHILDDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEAS
CCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKV
CCCCHHEEHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDR
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHCHHHHHHHHHHCCCCEEHHHHHHC
FENGQVVFKEADL
CCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA