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The map label for this gene is eda [H]

Identifier: 116515570

GI number: 116515570

Start: 289533

End: 290162

Strand: Reverse

Name: eda [H]

Synonym: SPD_0289

Alternate gene names: 116515570

Gene position: 290162-289533 (Counterclockwise)

Preceding gene: 116516452

Following gene: 116516850

Centisome position: 14.18

GC content: 45.08

Gene sequence:

>630_bases
ATGACCAAATCAGATACGATTATTGAACTAAAAAAACAGAAAATTGTCGCTGTCATTCGAGGAAATACAAAGGAAGAAGG
ACTACAAGCCTCGATTGCTTGTATCAAGGGCGGTATCAAAGCTATTGAAATCGCCTATACCAATCAGTATGCAGGACAAA
TCATCAAGGAACTTGTAGACTTGTATCAGGACGATCAGAGTGTTTGTATCGGTGCAGGTACTGTGCTTGATGCCGTAACT
GCTAGAGATGCCATTCTAGCTGGAGCAAATTACGTTGTTTCTCCATCTTTCCATGCTGAAACTGCGAAAATGTGCAATCT
CTACAGCACACCGTACATTCCAGGCTGTATTACCCTCACAGAGATCACGACTGCACTTGAAGCCGGTAGTGAAATCATCA
AACTCTTCCCAGGTAGTGCTCTCAGTCCAGCATATATCTCTGCAGTCAAGGCACCGATCCCACAAGTTTCCGTAATGGTA
ACCGGAGGAGTCGACCTAAACAACATCCCTCAATGGTTCGCTGCTGGTGCAGATGCCGTTGGAATTGGTGGCGAACTCAA
TAAACTCGCTTCCCAAGGCAACTTTGACCGCATCAGCGAGATTGCCCAACAGTATGTTACACTCAGATAA

Upstream 100 bases:

>100_bases
TCTCAAATGCACTCTTCCAGGAGACCATCTCTCCACTTCCGCAACTAGTATTGAAAATTTACTGGCAAATGCACAAGATA
TCATTCGTTAGGAGAATTAC

Downstream 100 bases:

>100_bases
AATCATAACCACCCGTCAAACGGGTGGTTTATCCCAGAGCTATAAGCCCAAATCATCAGCCAGCGCCTAAAGACGCTGGC
TTTCACGTTGTTCAAGCCTT

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEIAYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVT
ARDAILAGANYVVSPSFHAETAKMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
TGGVDLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR

Sequences:

>Translated_209_residues
MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEIAYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVT
ARDAILAGANYVVSPSFHAETAKMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
TGGVDLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR
>Mature_208_residues
TKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEIAYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTA
RDAILAGANYVVSPSFHAETAKMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMVT
GGVDLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR

Specific function: D-galactonate degradation; first step. D-galactonate degradation; third step. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI48994954, Length=196, Percent_Identity=36.2244897959184, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788156, Length=186, Percent_Identity=26.3440860215054, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 22083; Mature: 21951

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEIAYTNQYAGQIIKELVD
CCCCCHHHEEHHCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHH
LYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETAKMCNLYSTPYIPGCITLT
HHCCCCCEEEECHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEHHH
EITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMVTGGVDLNNIPQWFAAGADAV
HHHHHHHCCCHHEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCE
GIGGELNKLASQGNFDRISEIAQQYVTLR
ECCHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEIAYTNQYAGQIIKELVD
CCCCHHHEEHHCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHH
LYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETAKMCNLYSTPYIPGCITLT
HHCCCCCEEEECHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEHHH
EITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMVTGGVDLNNIPQWFAAGADAV
HHHHHHHCCCHHEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCE
GIGGELNKLASQGNFDRISEIAQQYVTLR
ECCHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]