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The map label for this gene is macB [H]

Identifier: 116496311

GI number: 116496311

Start: 2876445

End: 2877635

Strand: Direct

Name: macB [H]

Synonym: LSEI_2895

Alternate gene names: 116496311

Gene position: 2876445-2877635 (Clockwise)

Preceding gene: 116496310

Following gene: 116496314

Centisome position: 99.35

GC content: 45.0

Gene sequence:

>1191_bases
ATGCGAATAACTGAATTAATTCGAATTTCCTTCCGTGCGCTAACTGCTAACAAACGCCGCAGCCTCCTAACCATGCTTGG
CATTGTCATCGGTATCACTTCTGTTGTAACCATCATGGCACTCGGTAACGGTATCAAAGCTGCCACACTCAAAAATTTGC
AAACTGATCAATCTGGCCAACATACGGCTGAAATCACCTTCCTTCCTGAAAGTAGCACTGCCTCCACTGCTGGTTTTAAG
GAAGATGATGTGGATCTCGCCTATCAAACCGCTCCAGACAAAATCAAAAAAGTGACTATCAAACATGAAAAAGAACGCCT
ACAACTGAATGGTCAGTTAGCCAATCAAGATACGATGCTATCTGCCACACTTGTTACATCTATGCCTAAAGTGCAACTTG
CAGCTGGGCATAAACTAAACCCTGATTCTTTACAAACAGATGGACATGATGTGCTTTTGTCGAAAAAGTTAGCTAAAAAG
GTCTTTCATGGCAATGCGGCCGCGTTGACGTCATCTGTTTTTATCGGGAAGCGAAGCTACAACATTGTTGGTATTTTCAA
CACGCCTAAAGAGTCCTATTCAGCTTTAGATGTTGACGTTTTAATTCCTGAAAAGGCTTATACCGCTGGCCAGTTAAACC
CAGGAGGGCAAAAATTGGCCATCACCTTCCAACGTGGCAGTGACATTTCCCAGTTGGCAAACGCCATCGTTCGTCAGTTG
AAGAAATCTGGTACTGAACGCCGCAATGGCTCGTACCAATATTTTGATTATGGTGAATTACTAAAGGGTATCGGTGATGT
GATCAGCGGTTTAACGTTGTTCGTCGGGGCCATTGCGGGTATTTCGCTACTGATCGCAGGTGTCGGTGTCATGAACATGA
TGTACATTTCCGCCTCCGAACGTTCACAGGAAATTGGCATCAGAATGGCCGTTGGCGCTACCCCAGCAGAAATTATGAAA
CAGTTTCTGTTAGAGTCAGTCATGCTGACATTAACCGGCGGCGTTGTGGGTCTTGTTCTCGGTGGCTTGATTGCCTGGAT
GATCACAGCGTTCTTGCCATTTAAACCCGTCATAACGCTTGGTTCCATCATCGGCACCTTTGCAATTTCCAGCATTGTCG
GCATTGTTTTTGGCATCCTGCCAGCTAAAAGTGCTGCCAATAAGAACCTGATCGATATTCTGAAATCATAA

Upstream 100 bases:

>100_bases
ACCATCATTATGGTGACGCATGATGAACACGTGGCGCTACAAAGTGATCGCATGATTAAAGTATTAGACGGGCAGATCAT
CAGTGACACGGAGGTTAGCC

Downstream 100 bases:

>100_bases
AAATGCTCCCATCTAAGTGGCAGCATGCAGCTTTCTATTTCTACATTGAAAGTTCTTGAACCAACGAAAAAACGGTTAGA
TCTGCGAGATCTAACCGTTT

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRITELIRISFRALTANKRRSLLTMLGIVIGITSVVTIMALGNGIKAATLKNLQTDQSGQHTAEITFLPESSTASTAGFK
EDDVDLAYQTAPDKIKKVTIKHEKERLQLNGQLANQDTMLSATLVTSMPKVQLAAGHKLNPDSLQTDGHDVLLSKKLAKK
VFHGNAAALTSSVFIGKRSYNIVGIFNTPKESYSALDVDVLIPEKAYTAGQLNPGGQKLAITFQRGSDISQLANAIVRQL
KKSGTERRNGSYQYFDYGELLKGIGDVISGLTLFVGAIAGISLLIAGVGVMNMMYISASERSQEIGIRMAVGATPAEIMK
QFLLESVMLTLTGGVVGLVLGGLIAWMITAFLPFKPVITLGSIIGTFAISSIVGIVFGILPAKSAANKNLIDILKS

Sequences:

>Translated_396_residues
MRITELIRISFRALTANKRRSLLTMLGIVIGITSVVTIMALGNGIKAATLKNLQTDQSGQHTAEITFLPESSTASTAGFK
EDDVDLAYQTAPDKIKKVTIKHEKERLQLNGQLANQDTMLSATLVTSMPKVQLAAGHKLNPDSLQTDGHDVLLSKKLAKK
VFHGNAAALTSSVFIGKRSYNIVGIFNTPKESYSALDVDVLIPEKAYTAGQLNPGGQKLAITFQRGSDISQLANAIVRQL
KKSGTERRNGSYQYFDYGELLKGIGDVISGLTLFVGAIAGISLLIAGVGVMNMMYISASERSQEIGIRMAVGATPAEIMK
QFLLESVMLTLTGGVVGLVLGGLIAWMITAFLPFKPVITLGSIIGTFAISSIVGIVFGILPAKSAANKNLIDILKS
>Mature_396_residues
MRITELIRISFRALTANKRRSLLTMLGIVIGITSVVTIMALGNGIKAATLKNLQTDQSGQHTAEITFLPESSTASTAGFK
EDDVDLAYQTAPDKIKKVTIKHEKERLQLNGQLANQDTMLSATLVTSMPKVQLAAGHKLNPDSLQTDGHDVLLSKKLAKK
VFHGNAAALTSSVFIGKRSYNIVGIFNTPKESYSALDVDVLIPEKAYTAGQLNPGGQKLAITFQRGSDISQLANAIVRQL
KKSGTERRNGSYQYFDYGELLKGIGDVISGLTLFVGAIAGISLLIAGVGVMNMMYISASERSQEIGIRMAVGATPAEIMK
QFLLESVMLTLTGGVVGLVLGGLIAWMITAFLPFKPVITLGSIIGTFAISSIVGIVFGILPAKSAANKNLIDILKS

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=408, Percent_Identity=29.1666666666667, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42269; Mature: 42269

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITELIRISFRALTANKRRSLLTMLGIVIGITSVVTIMALGNGIKAATLKNLQTDQSGQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
HTAEITFLPESSTASTAGFKEDDVDLAYQTAPDKIKKVTIKHEKERLQLNGQLANQDTML
CEEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCHHH
SATLVTSMPKVQLAAGHKLNPDSLQTDGHDVLLSKKLAKKVFHGNAAALTSSVFIGKRSY
HHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCC
NIVGIFNTPKESYSALDVDVLIPEKAYTAGQLNPGGQKLAITFQRGSDISQLANAIVRQL
EEEEEECCCCHHHCEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
KKSGTERRNGSYQYFDYGELLKGIGDVISGLTLFVGAIAGISLLIAGVGVMNMMYISASE
HHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
RSQEIGIRMAVGATPAEIMKQFLLESVMLTLTGGVVGLVLGGLIAWMITAFLPFKPVITL
CCHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
GSIIGTFAISSIVGIVFGILPAKSAANKNLIDILKS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MRITELIRISFRALTANKRRSLLTMLGIVIGITSVVTIMALGNGIKAATLKNLQTDQSGQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
HTAEITFLPESSTASTAGFKEDDVDLAYQTAPDKIKKVTIKHEKERLQLNGQLANQDTML
CEEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCEECCCCHHH
SATLVTSMPKVQLAAGHKLNPDSLQTDGHDVLLSKKLAKKVFHGNAAALTSSVFIGKRSY
HHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCC
NIVGIFNTPKESYSALDVDVLIPEKAYTAGQLNPGGQKLAITFQRGSDISQLANAIVRQL
EEEEEECCCCHHHCEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
KKSGTERRNGSYQYFDYGELLKGIGDVISGLTLFVGAIAGISLLIAGVGVMNMMYISASE
HHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
RSQEIGIRMAVGATPAEIMKQFLLESVMLTLTGGVVGLVLGGLIAWMITAFLPFKPVITL
CCHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
GSIIGTFAISSIVGIVFGILPAKSAANKNLIDILKS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA