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The map label for this gene is rnhA [H]

Identifier: 116496073

GI number: 116496073

Start: 2630372

End: 2630854

Strand: Direct

Name: rnhA [H]

Synonym: LSEI_2646

Alternate gene names: 116496073

Gene position: 2630372-2630854 (Clockwise)

Preceding gene: 116496070

Following gene: 116496075

Centisome position: 90.85

GC content: 46.58

Gene sequence:

>483_bases
ATGGCTGAATCAATTGTACTTTATACAGATGGCGGTAATCGCAATACAGGAAATCAGGCGGGTGGATCGGTTCGCCCCAC
GGATAAAAGCGCATGGGCCGCATTGCTGATCTACGGAGATCACGAAAAAATGCTATCTGACGGCGACTATGGCCGAACGA
ATAATTATATGGAAATTATGGCCGTTATTCAAGGCTTAAAAGCCCTCAAACGCACAGATATTCCCGTCGATGTTTATTCC
GACTCTGCTTACGTCATCAACACCATGCAGCAACGTTGGTGGGTAAAATGGCAACAAAACAATTGGCGCAACCATGGCAA
ACCAGTTAAAAATGCCGAGCTTTGGCAGGCCTTGTTGCACCAAGTCAATCGCTTTGAAACGATTACCTTTCACAAGGTCA
AAGGCCATGCCACCAATCGCAACAACAATCGCGTCGATGCGGCCTTGAATCAAACCATGGACCAGCTTGACGATCATGTT
TAA

Upstream 100 bases:

>100_bases
CCATGCAGCAGCCTCTTTTCAAAATTTTTTCTTAGTGATGTGTCTAGCCATCTAAAACGCGTTCCCCTACAATAGATAGC
AGTTAGAAAGCGAGGAAATC

Downstream 100 bases:

>100_bases
CTATTTTACCCCTGATGGCCGAGAAATGCTTCACCATAAGTCTCAGCTAAGAAACTATGAATCACCTGCTGCATGCGCTG
CACAGAAGGTGATTTTTTTA

Product: RNase H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MAESIVLYTDGGNRNTGNQAGGSVRPTDKSAWAALLIYGDHEKMLSDGDYGRTNNYMEIMAVIQGLKALKRTDIPVDVYS
DSAYVINTMQQRWWVKWQQNNWRNHGKPVKNAELWQALLHQVNRFETITFHKVKGHATNRNNNRVDAALNQTMDQLDDHV

Sequences:

>Translated_160_residues
MAESIVLYTDGGNRNTGNQAGGSVRPTDKSAWAALLIYGDHEKMLSDGDYGRTNNYMEIMAVIQGLKALKRTDIPVDVYS
DSAYVINTMQQRWWVKWQQNNWRNHGKPVKNAELWQALLHQVNRFETITFHKVKGHATNRNNNRVDAALNQTMDQLDDHV
>Mature_159_residues
AESIVLYTDGGNRNTGNQAGGSVRPTDKSAWAALLIYGDHEKMLSDGDYGRTNNYMEIMAVIQGLKALKRTDIPVDVYSD
SAYVINTMQQRWWVKWQQNNWRNHGKPVKNAELWQALLHQVNRFETITFHKVKGHATNRNNNRVDAALNQTMDQLDDHV

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786408, Length=160, Percent_Identity=35.625, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 18315; Mature: 18184

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESIVLYTDGGNRNTGNQAGGSVRPTDKSAWAALLIYGDHEKMLSDGDYGRTNNYMEIM
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCHHHHH
AVIQGLKALKRTDIPVDVYSDSAYVINTMQQRWWVKWQQNNWRNHGKPVKNAELWQALLH
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHH
QVNRFETITFHKVKGHATNRNNNRVDAALNQTMDQLDDHV
HHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AESIVLYTDGGNRNTGNQAGGSVRPTDKSAWAALLIYGDHEKMLSDGDYGRTNNYMEIM
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCCHHHHH
AVIQGLKALKRTDIPVDVYSDSAYVINTMQQRWWVKWQQNNWRNHGKPVKNAELWQALLH
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHH
QVNRFETITFHKVKGHATNRNNNRVDAALNQTMDQLDDHV
HHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA