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The map label for this gene is yghA [C]

Identifier: 116494697

GI number: 116494697

Start: 1184012

End: 1184947

Strand: Direct

Name: yghA [C]

Synonym: LSEI_1203

Alternate gene names: 116494697

Gene position: 1184012-1184947 (Clockwise)

Preceding gene: 116494696

Following gene: 116494698

Centisome position: 40.89

GC content: 52.03

Gene sequence:

>936_bases
ATGCGGGAACCGATACGACATTGGACGCAAAAGAATATGCCTGATCTTCACGGCAGCTATGCGGTGGTAACAGGTGGTAC
CAGCGGAGTTGGGTTTGCAATGAGTGCTGCTTTGTTGCGGCACGGGGCGACGGTGATCATCGTTGGCAAACAGGCATCAA
AAGGCGTCACTGCTGCAGCCAAGTTAAGGGCGCAAACCGGTCAACAAAATGTCACGTTTATGGGCGCTGATCTGGCGGAT
CAAGCAGCCACTAAACACTTAGCCAACCGCCTGCTGAGGATGCTTCCTAAGCTGGATATTTTAATCAATAATGCCGGTGT
GATGATGCCCGCTAAACGTACCTTGACCCGTGACGGCCTCGAGCTGATGTGGGCAGTGAATTATTTTGCCGGATTTATCT
TAACAAGCGAACTGATGCCGCTACTATTGCGATCGGATCATGCCCGTGTGGTTAACGTTGCCTCAATCGCCATGGGTCGA
CCACATTTGACCTTTAATCAGTTTGATGGCCATGACTATCGCCCTTGGACGATTTATACGACTACCAAGCTGGCGCAAGC
GATGATGGTGGTTAAGCTCAATCAGCTATTGACAGAGGCAGGACAGTCGGTGACCGTGACTGGCTCAAGTCCGGGATTAG
CCGCAACGAGTTTGAAAACAATCAGCTCACGGAAAACTGCGTGGTTGATGCGAATGGGTGCGTTGAGTTTTCGCTTGCTG
CCGTTTCTCCGGCAGTCGCCAGATCAGGCGGCATTGCCAGCACTGTACGCCGCAACTGATCCCAATGCGCAAGGCGGCGT
GATTTATGCACCACATGCATGGCGTGGTTTGCGAGGTTACCCGGCATTATGGGCTTGGAATCAGCGGCCCGAATTACACG
ATCAGAAGTTGCTTGATCGTTTATATCGGGCTTCACGCAATGTAACTGGCGTATGA

Upstream 100 bases:

>100_bases
GCGTGCACAAGGCAACCTGCGGGTGATGTTGAAACGGCGTAAAAAGGCATAAATTCTTGCAGTCAAATGGCAGTTGTTGT
TGAAACGGAGGTAGTGGCCT

Downstream 100 bases:

>100_bases
TTGCCATTTTGGGTACGTTAGATTTTCTAAGAAGCGACTTTGCTAATGCCCCAAAAGCATCATTTCTGCTGATCCCATGC
TATTTTTGCTGTGATTAGCG

Product: Short-chain alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MREPIRHWTQKNMPDLHGSYAVVTGGTSGVGFAMSAALLRHGATVIIVGKQASKGVTAAAKLRAQTGQQNVTFMGADLAD
QAATKHLANRLLRMLPKLDILINNAGVMMPAKRTLTRDGLELMWAVNYFAGFILTSELMPLLLRSDHARVVNVASIAMGR
PHLTFNQFDGHDYRPWTIYTTTKLAQAMMVVKLNQLLTEAGQSVTVTGSSPGLAATSLKTISSRKTAWLMRMGALSFRLL
PFLRQSPDQAALPALYAATDPNAQGGVIYAPHAWRGLRGYPALWAWNQRPELHDQKLLDRLYRASRNVTGV

Sequences:

>Translated_311_residues
MREPIRHWTQKNMPDLHGSYAVVTGGTSGVGFAMSAALLRHGATVIIVGKQASKGVTAAAKLRAQTGQQNVTFMGADLAD
QAATKHLANRLLRMLPKLDILINNAGVMMPAKRTLTRDGLELMWAVNYFAGFILTSELMPLLLRSDHARVVNVASIAMGR
PHLTFNQFDGHDYRPWTIYTTTKLAQAMMVVKLNQLLTEAGQSVTVTGSSPGLAATSLKTISSRKTAWLMRMGALSFRLL
PFLRQSPDQAALPALYAATDPNAQGGVIYAPHAWRGLRGYPALWAWNQRPELHDQKLLDRLYRASRNVTGV
>Mature_311_residues
MREPIRHWTQKNMPDLHGSYAVVTGGTSGVGFAMSAALLRHGATVIIVGKQASKGVTAAAKLRAQTGQQNVTFMGADLAD
QAATKHLANRLLRMLPKLDILINNAGVMMPAKRTLTRDGLELMWAVNYFAGFILTSELMPLLLRSDHARVVNVASIAMGR
PHLTFNQFDGHDYRPWTIYTTTKLAQAMMVVKLNQLLTEAGQSVTVTGSSPGLAATSLKTISSRKTAWLMRMGALSFRLL
PFLRQSPDQAALPALYAATDPNAQGGVIYAPHAWRGLRGYPALWAWNQRPELHDQKLLDRLYRASRNVTGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI193804850, Length=301, Percent_Identity=32.2259136212625, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI146231950, Length=213, Percent_Identity=36.6197183098592, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI225579078, Length=299, Percent_Identity=29.4314381270903, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI166795268, Length=244, Percent_Identity=31.9672131147541, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI10190746, Length=265, Percent_Identity=30.188679245283, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI186928839, Length=298, Percent_Identity=29.1946308724832, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7706523, Length=294, Percent_Identity=27.5510204081633, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI19923931, Length=264, Percent_Identity=29.5454545454545, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87082160, Length=214, Percent_Identity=28.0373831775701, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=209, Percent_Identity=32.0574162679426, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17505416, Length=268, Percent_Identity=27.2388059701493, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532805, Length=261, Percent_Identity=26.8199233716475, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193207620, Length=260, Percent_Identity=26.5384615384615, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72001364, Length=260, Percent_Identity=27.3076923076923, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17532791, Length=305, Percent_Identity=24.2622950819672, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565532, Length=137, Percent_Identity=32.1167883211679, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533174, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533172, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992402, Length=260, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=212, Percent_Identity=27.3584905660377, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=145, Percent_Identity=33.7931034482759, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=279, Percent_Identity=26.8817204301075, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161076371, Length=258, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI22024069, Length=251, Percent_Identity=31.0756972111554, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586328, Length=251, Percent_Identity=30.2788844621514, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24656154, Length=265, Percent_Identity=29.811320754717, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19922628, Length=265, Percent_Identity=29.811320754717, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573296, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45554248, Length=271, Percent_Identity=28.7822878228782, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640117, Length=271, Percent_Identity=28.7822878228782, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921754, Length=259, Percent_Identity=28.1853281853282, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24647931, Length=273, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647946, Length=209, Percent_Identity=26.7942583732057, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45553409, Length=199, Percent_Identity=26.6331658291457, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647948, Length=199, Percent_Identity=26.6331658291457, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20129347, Length=255, Percent_Identity=25.4901960784314, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34085; Mature: 34085

Theoretical pI: Translated: 11.09; Mature: 11.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPIRHWTQKNMPDLHGSYAVVTGGTSGVGFAMSAALLRHGATVIIVGKQASKGVTAAA
CCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KLRAQTGQQNVTFMGADLADQAATKHLANRLLRMLPKLDILINNAGVMMPAKRTLTRDGL
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHCCH
ELMWAVNYFAGFILTSELMPLLLRSDHARVVNVASIAMGRPHLTFNQFDGHDYRPWTIYT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCEEECCCCCCCCCEEEEE
TTKLAQAMMVVKLNQLLTEAGQSVTVTGSSPGLAATSLKTISSRKTAWLMRMGALSFRLL
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLRQSPDQAALPALYAATDPNAQGGVIYAPHAWRGLRGYPALWAWNQRPELHDQKLLDR
HHHHCCCCCHHCCEEEECCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHH
LYRASRNVTGV
HHHHCCCCCCC
>Mature Secondary Structure
MREPIRHWTQKNMPDLHGSYAVVTGGTSGVGFAMSAALLRHGATVIIVGKQASKGVTAAA
CCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
KLRAQTGQQNVTFMGADLADQAATKHLANRLLRMLPKLDILINNAGVMMPAKRTLTRDGL
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHHCCH
ELMWAVNYFAGFILTSELMPLLLRSDHARVVNVASIAMGRPHLTFNQFDGHDYRPWTIYT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCEEECCCCCCCCCEEEEE
TTKLAQAMMVVKLNQLLTEAGQSVTVTGSSPGLAATSLKTISSRKTAWLMRMGALSFRLL
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFLRQSPDQAALPALYAATDPNAQGGVIYAPHAWRGLRGYPALWAWNQRPELHDQKLLDR
HHHHCCCCCHHCCEEEECCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHH
LYRASRNVTGV
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]