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The map label for this gene is sdaAA [H]

Identifier: 116494694

GI number: 116494694

Start: 1181226

End: 1182092

Strand: Direct

Name: sdaAA [H]

Synonym: LSEI_1200

Alternate gene names: 116494694

Gene position: 1181226-1182092 (Clockwise)

Preceding gene: 116494693

Following gene: 116494695

Centisome position: 40.8

GC content: 51.21

Gene sequence:

>867_bases
ATGTTTTATACCGTCAAAGAATTGATTGAGCAAAGTCACGCGTTTCCATCTGTTGCTGCGTTAATGGTGCATACCGAGGT
TGAAAACTCGACACGGACGGAGGCACAAGTTCGCCATCTTATGAGCCGCAATCTGGAAGTGATGGAACGATCCGTCAAAG
AAGGCATCGCTGGCGTCAAAAGTGTTACCGGTTTGACTGGCGGCGAGGCGAAGAAATTAGACGCTTATGTCACCAGTGGT
CAGTTCATGAGCGGCAAGCCGATCATGGAGGCTGTTCGCAATGCGGTTGCTGTTAACGAGGTTAATGCCAAAATGGGCTT
GATTTGTGCCACACCCACTGCAGGATCAGCTGGCGTTTTAGCTGGTGTTCTGCTTGCTATGCGTGATCGGTTGCATCTAA
GTCATGATCAACAGTTGGATTTTCTTTTTACCGCTGGTGCGTTTGGCCTAGTGATTGCCAATAATGCGGGAATTGCAGGT
GCAGAAGGCGGCTGCCAAGAGGAAGTCGGTTCTGCGAGTGCAATGGCGGCAGCTGCGTTGGTAACGGCTAATGGCGGTAC
GGTGGAGCAAGCAGCGACTGCAGTTGCCATTACCTTACAGAACATGCTCGGGTTAGTCTGTGATCCAGTCGCTGGGTTAG
TTGAGGTGCCGTGTGTAAAACGCAACGCGCTGGGCGCCAGTCAGGCGATGATTTCTGCTGACATGGCGTTGGCTGGTTGC
ATCAGTGTTATTCCGGCTGATGAAGTGATTGAGGCTGTGAATCGTGTCGGGATGCAATTACCAGCGACCTTACGGGAAAC
AGGCGAAGGCGGCTTAGCAACGACACCAACCGGATTGCGTTTGAAAGAGGAAATTTTCGGTAAATAA

Upstream 100 bases:

>100_bases
GGCTAAGTTGAAACAATTGCCGCATATGGTGAATGTCACTTACTTCGAATGACAGTCGTTTTTAATTGTTGTCCCTGATG
TTTTGATAAAGGAGTCGCCT

Downstream 100 bases:

>100_bases
TCATTGTCAGTCTTGGCTATTTCAGGACGTGATATTTGTGGAGATGCCCCAAGCTGGGTGTTAGCGTCAGTTGCAGTTTA
AACGGAAACACAGGAGGAGC

Product: L-serine deaminase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MFYTVKELIEQSHAFPSVAALMVHTEVENSTRTEAQVRHLMSRNLEVMERSVKEGIAGVKSVTGLTGGEAKKLDAYVTSG
QFMSGKPIMEAVRNAVAVNEVNAKMGLICATPTAGSAGVLAGVLLAMRDRLHLSHDQQLDFLFTAGAFGLVIANNAGIAG
AEGGCQEEVGSASAMAAAALVTANGGTVEQAATAVAITLQNMLGLVCDPVAGLVEVPCVKRNALGASQAMISADMALAGC
ISVIPADEVIEAVNRVGMQLPATLRETGEGGLATTPTGLRLKEEIFGK

Sequences:

>Translated_288_residues
MFYTVKELIEQSHAFPSVAALMVHTEVENSTRTEAQVRHLMSRNLEVMERSVKEGIAGVKSVTGLTGGEAKKLDAYVTSG
QFMSGKPIMEAVRNAVAVNEVNAKMGLICATPTAGSAGVLAGVLLAMRDRLHLSHDQQLDFLFTAGAFGLVIANNAGIAG
AEGGCQEEVGSASAMAAAALVTANGGTVEQAATAVAITLQNMLGLVCDPVAGLVEVPCVKRNALGASQAMISADMALAGC
ISVIPADEVIEAVNRVGMQLPATLRETGEGGLATTPTGLRLKEEIFGK
>Mature_288_residues
MFYTVKELIEQSHAFPSVAALMVHTEVENSTRTEAQVRHLMSRNLEVMERSVKEGIAGVKSVTGLTGGEAKKLDAYVTSG
QFMSGKPIMEAVRNAVAVNEVNAKMGLICATPTAGSAGVLAGVLLAMRDRLHLSHDQQLDFLFTAGAFGLVIANNAGIAG
AEGGCQEEVGSASAMAAAALVTANGGTVEQAATAVAITLQNMLGLVCDPVAGLVEVPCVKRNALGASQAMISADMALAGC
ISVIPADEVIEAVNRVGMQLPATLRETGEGGLATTPTGLRLKEEIFGK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=285, Percent_Identity=32.9824561403509, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788116, Length=182, Percent_Identity=43.956043956044, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789161, Length=269, Percent_Identity=35.6877323420074, Blast_Score=120, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29695; Mature: 29695

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYTVKELIEQSHAFPSVAALMVHTEVENSTRTEAQVRHLMSRNLEVMERSVKEGIAGVK
CCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVTGLTGGEAKKLDAYVTSGQFMSGKPIMEAVRNAVAVNEVNAKMGLICATPTAGSAGVL
HHCCCCCCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
AGVLLAMRDRLHLSHDQQLDFLFTAGAFGLVIANNAGIAGAEGGCQEEVGSASAMAAAAL
HHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHE
VTANGGTVEQAATAVAITLQNMLGLVCDPVAGLVEVPCVKRNALGASQAMISADMALAGC
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
ISVIPADEVIEAVNRVGMQLPATLRETGEGGLATTPTGLRLKEEIFGK
HHHCCHHHHHHHHHHCCCCCCHHHHHCCCCCCEECCCCCEEHHHHCCC
>Mature Secondary Structure
MFYTVKELIEQSHAFPSVAALMVHTEVENSTRTEAQVRHLMSRNLEVMERSVKEGIAGVK
CCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVTGLTGGEAKKLDAYVTSGQFMSGKPIMEAVRNAVAVNEVNAKMGLICATPTAGSAGVL
HHCCCCCCCCHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
AGVLLAMRDRLHLSHDQQLDFLFTAGAFGLVIANNAGIAGAEGGCQEEVGSASAMAAAAL
HHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCHHHHCCHHHHHHHHE
VTANGGTVEQAATAVAITLQNMLGLVCDPVAGLVEVPCVKRNALGASQAMISADMALAGC
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
ISVIPADEVIEAVNRVGMQLPATLRETGEGGLATTPTGLRLKEEIFGK
HHHCCHHHHHHHHHHCCCCCCHHHHHCCCCCCEECCCCCEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]