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The map label for this gene is metI [H]

Identifier: 116494674

GI number: 116494674

Start: 1161530

End: 1162219

Strand: Direct

Name: metI [H]

Synonym: LSEI_1179

Alternate gene names: 116494674

Gene position: 1161530-1162219 (Clockwise)

Preceding gene: 116494673

Following gene: 116494675

Centisome position: 40.12

GC content: 49.28

Gene sequence:

>690_bases
ATGGGACAGTTCTTTACAAAATATTTTCCTAACGTGGTGCCTATCTGGTCGGGTGACGGCGGGGTGACTCAGGCAATCAA
CGAAACGTTGTATATGACTGTGTTGACAGCAGTTGTTGCCGGCATTCTCGGGATTGTTATTGGAATTCTGCTGGTTCTAA
CCGATGAAGATGGTTTACTAGCCAACCAACCGTTTTATTTTATCCTCGATAAACTGGTTAACATTTTTCGGGCGGTGCCA
TTCATCATCTTGCTGGCAATCATGACCCCTGTGACGCGAGCCATTGTCGGGACGGGGATCGGACCAACTGCAGCCTTGGT
TCCTTTAATTGCAGGGACCACACCGTTTTATGCACGGCAGGTTCAAAATGCCTTATTGACAGTTGATCCTGGCGTCATCG
AGGCAGCTGAAGCAATGGGTGTTTCGCCGCCTGGCATTGTGTTGCGGGTTTACCTGCGCGAAGGTTTGTCAGAACTCATC
CGAGTTTCAGTCCTGACGATCATCTCTGTCATCGGCTTAACCGCTATGGCAGGTGCAGTTGGGGGCGGCGGCCTTGGGAA
TCTGGCGATCGCGGTCGGTTACCAACGTTACCAATACGACGTCATCATCGTTTCCTTAGTCTTTATTCTGGCGATCGTTT
TCTTGGTACAATTTATCGGTGACTTCTTCGCACGAAAAACCCATCATTAA

Upstream 100 bases:

>100_bases
GTTCTTTCCGGTGACCATGATGAAGTTGAATCCGGAATCGCGTATTTGAAACAGCAGGATGTCAAGATTGAAGACATTCT
TAAGAAGGAGGCCTAGACAG

Downstream 100 bases:

>100_bases
ATTTAAAACTCGTTTTGTAAGCAGAACTCGTGATAGCGTTCTGCTTTTTTTTGAACGCGTTTGCCGCTGTTCTTTTTATG
ACGTAGAATGGCGATATAAC

Product: ABC-type metal ion transport system, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MGQFFTKYFPNVVPIWSGDGGVTQAINETLYMTVLTAVVAGILGIVIGILLVLTDEDGLLANQPFYFILDKLVNIFRAVP
FIILLAIMTPVTRAIVGTGIGPTAALVPLIAGTTPFYARQVQNALLTVDPGVIEAAEAMGVSPPGIVLRVYLREGLSELI
RVSVLTIISVIGLTAMAGAVGGGGLGNLAIAVGYQRYQYDVIIVSLVFILAIVFLVQFIGDFFARKTHH

Sequences:

>Translated_229_residues
MGQFFTKYFPNVVPIWSGDGGVTQAINETLYMTVLTAVVAGILGIVIGILLVLTDEDGLLANQPFYFILDKLVNIFRAVP
FIILLAIMTPVTRAIVGTGIGPTAALVPLIAGTTPFYARQVQNALLTVDPGVIEAAEAMGVSPPGIVLRVYLREGLSELI
RVSVLTIISVIGLTAMAGAVGGGGLGNLAIAVGYQRYQYDVIIVSLVFILAIVFLVQFIGDFFARKTHH
>Mature_228_residues
GQFFTKYFPNVVPIWSGDGGVTQAINETLYMTVLTAVVAGILGIVIGILLVLTDEDGLLANQPFYFILDKLVNIFRAVPF
IILLAIMTPVTRAIVGTGIGPTAALVPLIAGTTPFYARQVQNALLTVDPGVIEAAEAMGVSPPGIVLRVYLREGLSELIR
VSVLTIISVIGLTAMAGAVGGGGLGNLAIAVGYQRYQYDVIIVSLVFILAIVFLVQFIGDFFARKTHH

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=202, Percent_Identity=44.5544554455446, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24348; Mature: 24217

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50928 ABC_TM1 ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQFFTKYFPNVVPIWSGDGGVTQAINETLYMTVLTAVVAGILGIVIGILLVLTDEDGLL
CCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ANQPFYFILDKLVNIFRAVPFIILLAIMTPVTRAIVGTGIGPTAALVPLIAGTTPFYARQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
VQNALLTVDPGVIEAAEAMGVSPPGIVLRVYLREGLSELIRVSVLTIISVIGLTAMAGAV
HHHHHEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GGGGLGNLAIAVGYQRYQYDVIIVSLVFILAIVFLVQFIGDFFARKTHH
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GQFFTKYFPNVVPIWSGDGGVTQAINETLYMTVLTAVVAGILGIVIGILLVLTDEDGLL
CCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ANQPFYFILDKLVNIFRAVPFIILLAIMTPVTRAIVGTGIGPTAALVPLIAGTTPFYARQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
VQNALLTVDPGVIEAAEAMGVSPPGIVLRVYLREGLSELIRVSVLTIISVIGLTAMAGAV
HHHHHEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GGGGLGNLAIAVGYQRYQYDVIIVSLVFILAIVFLVQFIGDFFARKTHH
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]