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The map label for this gene is pgi

Identifier: 116494625

GI number: 116494625

Start: 1112373

End: 1113713

Strand: Direct

Name: pgi

Synonym: LSEI_1126

Alternate gene names: 116494625

Gene position: 1112373-1113713 (Clockwise)

Preceding gene: 116494624

Following gene: 116494634

Centisome position: 38.42

GC content: 48.25

Gene sequence:

>1341_bases
ATGTCGTACATCAAATTTGATTCATCTAAGCTGGACAAGTTCGTTCATGCCAATGAACTTGAACAGATGCAGCCGTTAGT
GACTGCAGCTGACAAGGAATTGCGTGAAGGAACAGGTGCTGGTAAGGATTTCCGCGGCTTTATCGATTTGCCAGTCAACT
ATGACAAGGACGAATTTGCCCGGATTAAGGCAGCAGCCAAGAAAGTTCAAGGCAATTCTCAAGTCTTTGTTGCGATTGGG
ATTGGCGGTTCTTATTTAGGCGCACGGATGGCGGTTGATTTTCTTTCCCAGACTTTCCGTAACCTTGACCCTGATCTGAA
GTTCCCAGAAGTTTATTTTGCTGGTAACTCAATCTCTGGTACTTATCTGGCGGACTTGCTTGACATTATTGGCGACCGTG
ATTTCTCGATCAACGTGATCAGTAAGTCTGGTACCACGACTGAACCTTCAATTGCATTCCGTGTTCTGAAGGCAAAGTTG
ATCGAAAAGTATGGCAAAGATGGCGCAAAGGAACGGATTTATGCGACAACTGATCGTGCCAAGGGTGCTTTGAAGCAAGA
AGCAGACGCAGAAGGCTACGAAGAATTCGTTGTTCCTGATGATGTCGGCGGTCGGTTCTCTGTGATGTCCGCTGTTGGTC
TGTTGCCAATCGCTGTTGCAGGCGGTGACATTGACGAAATGATGCGTGGTCTCGGTGATGGTCGTAAGGCATACGCTTCA
GCTGATTTGAAGGAAAACGAAGCTTATCAGTACGCCGCATTGCGGAACATTTTGTATCGCAAGGGCTATACCACTGAATT
GCTGGAAAACTACGAACCAACGTTGCAATACCTTGGTGAATGGTGGAAGCAATTGATGGGTGAATCTGAAGGTAAGGACC
AGAAGGGGATCTATCCTTCAAGTGCCAACTTCAGTACTGACCTGCACAGTCTTGGCCAATACATTCAGGAAGGTCTGCGC
AACCTGATGGAAACCGTTGTCTGGGTTGAAGAACCAAACCGCGACCTAACCATTCCTGAAGATGCTAACAACCTTGACGG
CCTTGGCTACTTGGCTGGCAAGAAGATGTCCTTCGTTAACCGCAAGGCCTATGAAGGGGTTGTTCTCGCCCACACCGATG
GCGGCGTGCCAGTTATGACCGTCTCCATTCCAAAGCAGGATGCCTACACCTTAGGCTATCTGATCTATTTCTTCGAAGCT
GCCGTTTCAATCTCCGGCTACCTGAACGGGATCAACCCATTCAACCAGCCAGGTGTTGAAGCCTACAAGAAGAACATGTT
CGCATTGCTCGGCCGTCCGGGTTATGAGGATATGACCAAGGAATTGAACGCACGGCTTTAA

Upstream 100 bases:

>100_bases
TGAGTTATTTCGAATTAATAATTGACTTGACGTTTTTTATGAAACCACTCTCATATCGACTTTTGACAGTTACTTATGTA
TTTAGAGGAGGAAGCACACG

Downstream 100 bases:

>100_bases
TAGCGTGGGTTTGAGGTCGTTTGGATAGGAAAAAATGAGAGCCTCAAAATTGTGTTGTAAATGTTCGTGACTGAATTTTG
ACTGAATAGCCAAAAGGGTC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSYIKFDSSKLDKFVHANELEQMQPLVTAADKELREGTGAGKDFRGFIDLPVNYDKDEFARIKAAAKKVQGNSQVFVAIG
IGGSYLGARMAVDFLSQTFRNLDPDLKFPEVYFAGNSISGTYLADLLDIIGDRDFSINVISKSGTTTEPSIAFRVLKAKL
IEKYGKDGAKERIYATTDRAKGALKQEADAEGYEEFVVPDDVGGRFSVMSAVGLLPIAVAGGDIDEMMRGLGDGRKAYAS
ADLKENEAYQYAALRNILYRKGYTTELLENYEPTLQYLGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQEGLR
NLMETVVWVEEPNRDLTIPEDANNLDGLGYLAGKKMSFVNRKAYEGVVLAHTDGGVPVMTVSIPKQDAYTLGYLIYFFEA
AVSISGYLNGINPFNQPGVEAYKKNMFALLGRPGYEDMTKELNARL

Sequences:

>Translated_446_residues
MSYIKFDSSKLDKFVHANELEQMQPLVTAADKELREGTGAGKDFRGFIDLPVNYDKDEFARIKAAAKKVQGNSQVFVAIG
IGGSYLGARMAVDFLSQTFRNLDPDLKFPEVYFAGNSISGTYLADLLDIIGDRDFSINVISKSGTTTEPSIAFRVLKAKL
IEKYGKDGAKERIYATTDRAKGALKQEADAEGYEEFVVPDDVGGRFSVMSAVGLLPIAVAGGDIDEMMRGLGDGRKAYAS
ADLKENEAYQYAALRNILYRKGYTTELLENYEPTLQYLGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQEGLR
NLMETVVWVEEPNRDLTIPEDANNLDGLGYLAGKKMSFVNRKAYEGVVLAHTDGGVPVMTVSIPKQDAYTLGYLIYFFEA
AVSISGYLNGINPFNQPGVEAYKKNMFALLGRPGYEDMTKELNARL
>Mature_445_residues
SYIKFDSSKLDKFVHANELEQMQPLVTAADKELREGTGAGKDFRGFIDLPVNYDKDEFARIKAAAKKVQGNSQVFVAIGI
GGSYLGARMAVDFLSQTFRNLDPDLKFPEVYFAGNSISGTYLADLLDIIGDRDFSINVISKSGTTTEPSIAFRVLKAKLI
EKYGKDGAKERIYATTDRAKGALKQEADAEGYEEFVVPDDVGGRFSVMSAVGLLPIAVAGGDIDEMMRGLGDGRKAYASA
DLKENEAYQYAALRNILYRKGYTTELLENYEPTLQYLGEWWKQLMGESEGKDQKGIYPSSANFSTDLHSLGQYIQEGLRN
LMETVVWVEEPNRDLTIPEDANNLDGLGYLAGKKMSFVNRKAYEGVVLAHTDGGVPVMTVSIPKQDAYTLGYLIYFFEAA
VSISGYLNGINPFNQPGVEAYKKNMFALLGRPGYEDMTKELNARL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_LACC3 (Q03A55)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806359.1
- ProteinModelPortal:   Q03A55
- SMR:   Q03A55
- STRING:   Q03A55
- GeneID:   4419660
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1126
- eggNOG:   COG0166
- HOGENOM:   HBG615843
- OMA:   YVNDRAY
- ProtClustDB:   PRK14097
- BioCyc:   LCAS321967:LSEI_1126-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 49323; Mature: 49192

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 288-288 ACT_SITE 309-309 ACT_SITE 423-423

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYIKFDSSKLDKFVHANELEQMQPLVTAADKELREGTGAGKDFRGFIDLPVNYDKDEFA
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHH
RIKAAAKKVQGNSQVFVAIGIGGSYLGARMAVDFLSQTFRNLDPDLKFPEVYFAGNSISG
HHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCH
TYLADLLDIIGDRDFSINVISKSGTTTEPSIAFRVLKAKLIEKYGKDGAKERIYATTDRA
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHH
KGALKQEADAEGYEEFVVPDDVGGRFSVMSAVGLLPIAVAGGDIDEMMRGLGDGRKAYAS
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHCCCCCHHHHC
ADLKENEAYQYAALRNILYRKGYTTELLENYEPTLQYLGEWWKQLMGESEGKDQKGIYPS
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SANFSTDLHSLGQYIQEGLRNLMETVVWVEEPNRDLTIPEDANNLDGLGYLAGKKMSFVN
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCHHCCCHHHHHH
RKAYEGVVLAHTDGGVPVMTVSIPKQDAYTLGYLIYFFEAAVSISGYLNGINPFNQPGVE
HHHHCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AYKKNMFALLGRPGYEDMTKELNARL
HHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SYIKFDSSKLDKFVHANELEQMQPLVTAADKELREGTGAGKDFRGFIDLPVNYDKDEFA
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHH
RIKAAAKKVQGNSQVFVAIGIGGSYLGARMAVDFLSQTFRNLDPDLKFPEVYFAGNSISG
HHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCH
TYLADLLDIIGDRDFSINVISKSGTTTEPSIAFRVLKAKLIEKYGKDGAKERIYATTDRA
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHH
KGALKQEADAEGYEEFVVPDDVGGRFSVMSAVGLLPIAVAGGDIDEMMRGLGDGRKAYAS
HHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHCCCCCHHHHC
ADLKENEAYQYAALRNILYRKGYTTELLENYEPTLQYLGEWWKQLMGESEGKDQKGIYPS
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SANFSTDLHSLGQYIQEGLRNLMETVVWVEEPNRDLTIPEDANNLDGLGYLAGKKMSFVN
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCHHCCCHHHHHH
RKAYEGVVLAHTDGGVPVMTVSIPKQDAYTLGYLIYFFEAAVSISGYLNGINPFNQPGVE
HHHHCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AYKKNMFALLGRPGYEDMTKELNARL
HHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA