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The map label for this gene is glmM

Identifier: 116494522

GI number: 116494522

Start: 1003608

End: 1004972

Strand: Direct

Name: glmM

Synonym: LSEI_1018

Alternate gene names: 116494522

Gene position: 1003608-1004972 (Clockwise)

Preceding gene: 116494521

Following gene: 116494523

Centisome position: 34.66

GC content: 47.25

Gene sequence:

>1365_bases
ATGACAAAGTATTTTGGTACTGATGGCGTTCGTGGCATTGCAAACAAGGAACTAAGTCCGGAAATGGCTTTCCGGCTAGG
GCGGACAGGCGGCTATGTTTTGACGCAGCACAAAGAAGATGCGAGTCGACGCCCATTGGTTTTGGTTGCTCGCGATACAC
GAATCTCAGGGCAGATGTTGGCTGATGCTTTAATTGCTGGCTTGCTTTCTGTTGGGATTGAAGTGCTGGATTTAGGCGTG
ATCACAACGCCTGCTGTTGCTTATTTAATCAAGATTCAAGGCGCCGATGCTGGTATCCAGATTTCGGCGTCGCATAATCC
GGTTGCCGATAATGGCATCAAGTTCTTTGGAGCGGACGGCTACAAATTGTCTGACGATACTGAAGAAGAAATTGAAGCCT
TACTGGATGCACCAGAAGACAAACTTCCACGGCCAGCTGCTGAAGGATTAGGTACAGTAGACGATTATCCTGAAGGCGCA
CTCAAGTACACCCAATTTCTTGAGCAAACCTTGGCAGATGATCTGAGTGGCATTCATGTGTGCTTGGATGGCGCAAATGG
TGCAACGAGTGGGTTAGTTAGTCGAATTTTTGCTGATCTTGAGACCGATTTTGATACAATGGCAATCAGTCCAGATGGGC
TTAATATCAATGCTAACGTTGGTTCAACGCATCCGCAGGCGTTATCGAAATTTGTCGTCGAAAAAGGTGCTGATGTTGGC
CTCGCGTTTGACGGTGACGGTGATCGCTGTATCGCAGTTGATGAACAAGGCAATATCGTTGATGGCGACAAGATTATGTT
CATTCTCGGTAGTTATATGAAGTCACAGGGCCGGCTGAAGCAGGATACTGTCGTCACCACTGTTATGAGTAATCTTGGGT
TATATAAGGCATTAGAAGCGAATGGCATGAAGTCCGTGCAAACGGCCGTCGGTGATCGCCACGTTGTCGAGGCCATGCGC
AAAGATGGCTATAATATTGGCGGCGAACAGTCTGGCCACGTCATTTTGTTTGATTATCACAATACCGGGGATGGCATGCT
AACAGGCATTCACTTGTTAAATGTCATGAAGAAAACCGGCAAGAAGTTGTCTGAATTAGCCGCACCTGTTCAAGACTATC
CGCAGAAATTGGTTAATGTAAAAGTTGCGGACAAGGAAAATTGGCAAGCTTATCCAGAAATCCAAAGTGCCATTGATACC
GTCGAAAAAGAAATGGCCGGTGATGGCCGTGTTCTGGTTCGCCCTTCAGGCACTGAACCTTTGTTGCGGGTCATGGCCGA
AGCCAAAACCGAAGATTTGGTTTCCCGTTATGTGGATCAAATCGTGGATGTGGTGAAGCAAGAAATGGGCAGCAAGGAAG
ATTAG

Upstream 100 bases:

>100_bases
TTCGAGTTCGAGTGCCGCAAGCACCTCGAGTGCCAGTGAATCAGACTCAAGTACATCAACAAGCGACAATAATGGCTGAA
AGAAATGAGGAAGAATTAAG

Downstream 100 bases:

>100_bases
CTGCTGTCTTTATCAAAAATTTAAACTTTATTTTAACCGAGTTGTCACGGGTCTCATCGACAACTCGGTTTTTTTGTCTG
GTGATAGCATTCGCAATTGG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTKYFGTDGVRGIANKELSPEMAFRLGRTGGYVLTQHKEDASRRPLVLVARDTRISGQMLADALIAGLLSVGIEVLDLGV
ITTPAVAYLIKIQGADAGIQISASHNPVADNGIKFFGADGYKLSDDTEEEIEALLDAPEDKLPRPAAEGLGTVDDYPEGA
LKYTQFLEQTLADDLSGIHVCLDGANGATSGLVSRIFADLETDFDTMAISPDGLNINANVGSTHPQALSKFVVEKGADVG
LAFDGDGDRCIAVDEQGNIVDGDKIMFILGSYMKSQGRLKQDTVVTTVMSNLGLYKALEANGMKSVQTAVGDRHVVEAMR
KDGYNIGGEQSGHVILFDYHNTGDGMLTGIHLLNVMKKTGKKLSELAAPVQDYPQKLVNVKVADKENWQAYPEIQSAIDT
VEKEMAGDGRVLVRPSGTEPLLRVMAEAKTEDLVSRYVDQIVDVVKQEMGSKED

Sequences:

>Translated_454_residues
MTKYFGTDGVRGIANKELSPEMAFRLGRTGGYVLTQHKEDASRRPLVLVARDTRISGQMLADALIAGLLSVGIEVLDLGV
ITTPAVAYLIKIQGADAGIQISASHNPVADNGIKFFGADGYKLSDDTEEEIEALLDAPEDKLPRPAAEGLGTVDDYPEGA
LKYTQFLEQTLADDLSGIHVCLDGANGATSGLVSRIFADLETDFDTMAISPDGLNINANVGSTHPQALSKFVVEKGADVG
LAFDGDGDRCIAVDEQGNIVDGDKIMFILGSYMKSQGRLKQDTVVTTVMSNLGLYKALEANGMKSVQTAVGDRHVVEAMR
KDGYNIGGEQSGHVILFDYHNTGDGMLTGIHLLNVMKKTGKKLSELAAPVQDYPQKLVNVKVADKENWQAYPEIQSAIDT
VEKEMAGDGRVLVRPSGTEPLLRVMAEAKTEDLVSRYVDQIVDVVKQEMGSKED
>Mature_453_residues
TKYFGTDGVRGIANKELSPEMAFRLGRTGGYVLTQHKEDASRRPLVLVARDTRISGQMLADALIAGLLSVGIEVLDLGVI
TTPAVAYLIKIQGADAGIQISASHNPVADNGIKFFGADGYKLSDDTEEEIEALLDAPEDKLPRPAAEGLGTVDDYPEGAL
KYTQFLEQTLADDLSGIHVCLDGANGATSGLVSRIFADLETDFDTMAISPDGLNINANVGSTHPQALSKFVVEKGADVGL
AFDGDGDRCIAVDEQGNIVDGDKIMFILGSYMKSQGRLKQDTVVTTVMSNLGLYKALEANGMKSVQTAVGDRHVVEAMRK
DGYNIGGEQSGHVILFDYHNTGDGMLTGIHLLNVMKKTGKKLSELAAPVQDYPQKLVNVKVADKENWQAYPEIQSAIDTV
EKEMAGDGRVLVRPSGTEPLLRVMAEAKTEDLVSRYVDQIVDVVKQEMGSKED

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=448, Percent_Identity=42.4107142857143, Blast_Score=314, Evalue=7e-87,
Organism=Escherichia coli, GI1788361, Length=456, Percent_Identity=26.5350877192982, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_LACC3 (Q03AF8)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806256.1
- ProteinModelPortal:   Q03AF8
- STRING:   Q03AF8
- GeneID:   4421679
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1018
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   SAVMIHE
- PhylomeDB:   Q03AF8
- ProtClustDB:   PRK14316
- BioCyc:   LCAS321967:LSEI_1018-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48796; Mature: 48665

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYFGTDGVRGIANKELSPEMAFRLGRTGGYVLTQHKEDASRRPLVLVARDTRISGQML
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCHHHH
ADALIAGLLSVGIEVLDLGVITTPAVAYLIKIQGADAGIQISASHNPVADNGIKFFGADG
HHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCC
YKLSDDTEEEIEALLDAPEDKLPRPAAEGLGTVDDYPEGALKYTQFLEQTLADDLSGIHV
CCCCCCCHHHHHHHHCCCHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
CLDGANGATSGLVSRIFADLETDFDTMAISPDGLNINANVGSTHPQALSKFVVEKGADVG
EEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCCEE
LAFDGDGDRCIAVDEQGNIVDGDKIMFILGSYMKSQGRLKQDTVVTTVMSNLGLYKALEA
EEECCCCCEEEEECCCCCEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHC
NGMKSVQTAVGDRHVVEAMRKDGYNIGGEQSGHVILFDYHNTGDGMLTGIHLLNVMKKTG
CCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
KKLSELAAPVQDYPQKLVNVKVADKENWQAYPEIQSAIDTVEKEMAGDGRVLVRPSGTEP
HHHHHHHCCHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHH
LLRVMAEAKTEDLVSRYVDQIVDVVKQEMGSKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKYFGTDGVRGIANKELSPEMAFRLGRTGGYVLTQHKEDASRRPLVLVARDTRISGQML
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCHHHH
ADALIAGLLSVGIEVLDLGVITTPAVAYLIKIQGADAGIQISASHNPVADNGIKFFGADG
HHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCC
YKLSDDTEEEIEALLDAPEDKLPRPAAEGLGTVDDYPEGALKYTQFLEQTLADDLSGIHV
CCCCCCCHHHHHHHHCCCHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
CLDGANGATSGLVSRIFADLETDFDTMAISPDGLNINANVGSTHPQALSKFVVEKGADVG
EEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCCEE
LAFDGDGDRCIAVDEQGNIVDGDKIMFILGSYMKSQGRLKQDTVVTTVMSNLGLYKALEA
EEECCCCCEEEEECCCCCEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHC
NGMKSVQTAVGDRHVVEAMRKDGYNIGGEQSGHVILFDYHNTGDGMLTGIHLLNVMKKTG
CCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
KKLSELAAPVQDYPQKLVNVKVADKENWQAYPEIQSAIDTVEKEMAGDGRVLVRPSGTEP
HHHHHHHCCHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHH
LLRVMAEAKTEDLVSRYVDQIVDVVKQEMGSKED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA