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The map label for this gene is yycF [H]

Identifier: 116494457

GI number: 116494457

Start: 929474

End: 930121

Strand: Direct

Name: yycF [H]

Synonym: LSEI_0950

Alternate gene names: 116494457

Gene position: 929474-930121 (Clockwise)

Preceding gene: 116494456

Following gene: 116494458

Centisome position: 32.1

GC content: 48.92

Gene sequence:

>648_bases
ATGAACTATTTAATCGTTGAAGATGAACCGGCATTAGGCGAGACACTGCGCGCCTATTTGGCCAAAGACGGTCAGGCCGT
GCTAGCGACCTCGTTAGCGCAAGCCAATGAACGAGTCGCGCAGATTTCGCCCGATGTCATCATTTTAGATCTGAGCATGC
CCGATGGTGACGGCTTGACTTGGTTAGCGCAATGGCGGAAGCATTTGACTGCTAGGGTGATTGTTTTGACGGCTAATGAC
GAGGAGCTAACGATGCTAAAAGGACTCCGACTTGCTGATGATTACGTGGTAAAACCGGTTAGTTTACGTGTTTTAAAGGC
TCGCATTGCTAAACAGCTGCCGATGACAGTGCAACAATTTGGGGCGGTTAGCCTGAATTTAGCCACTGGTCAAGTGACGA
AAAATGAGACAGCGGTTGTGCTAACGGCGGCCGAGTATCGTTTGCTGGCCTATTTTTTTGCCAACCCCAATCAAATTTTG
GCAAGAGATCAGTTGCTAGCAGCCTTGTGGGACACGCGTGAGCAGTTTGTGGCGGATAATACTTTAACCGTGACCATCAA
ACGTCTGCGGGAAAAGCTTGAGGATGATCCGGCACATACGACCTTAATTCGGACTGTGCGGGGAATGGGGTATTTTATTG
ATGGTTAA

Upstream 100 bases:

>100_bases
TAAAAGCGATTGTTCAAGGTCCTTTAAAAAACGTTGTCATCCCCACAGCCATGTTTCTCCGGTATACTTTAATCAAGGTA
ATGATACGGGGGGTGGCATG

Downstream 100 bases:

>100_bases
GCATGATTATTGGGCTATGCCGGAAACCAAAAGTGTGCTGAGATTGACAGTGTGGTTGATAGTTATTTTGTGGGCCGCTT
TACTCACGGTGATGGTGCTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYLIVEDEPALGETLRAYLAKDGQAVLATSLAQANERVAQISPDVIILDLSMPDGDGLTWLAQWRKHLTARVIVLTAND
EELTMLKGLRLADDYVVKPVSLRVLKARIAKQLPMTVQQFGAVSLNLATGQVTKNETAVVLTAAEYRLLAYFFANPNQIL
ARDQLLAALWDTREQFVADNTLTVTIKRLREKLEDDPAHTTLIRTVRGMGYFIDG

Sequences:

>Translated_215_residues
MNYLIVEDEPALGETLRAYLAKDGQAVLATSLAQANERVAQISPDVIILDLSMPDGDGLTWLAQWRKHLTARVIVLTAND
EELTMLKGLRLADDYVVKPVSLRVLKARIAKQLPMTVQQFGAVSLNLATGQVTKNETAVVLTAAEYRLLAYFFANPNQIL
ARDQLLAALWDTREQFVADNTLTVTIKRLREKLEDDPAHTTLIRTVRGMGYFIDG
>Mature_215_residues
MNYLIVEDEPALGETLRAYLAKDGQAVLATSLAQANERVAQISPDVIILDLSMPDGDGLTWLAQWRKHLTARVIVLTAND
EELTMLKGLRLADDYVVKPVSLRVLKARIAKQLPMTVQQFGAVSLNLATGQVTKNETAVVLTAAEYRLLAYFFANPNQIL
ARDQLLAALWDTREQFVADNTLTVTIKRLREKLEDDPAHTTLIRTVRGMGYFIDG

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.0909090909091, Blast_Score=116, Evalue=9e-28,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=36.8181818181818, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=218, Percent_Identity=38.0733944954128, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=34.2105263157895, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.920704845815, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=34.2222222222222, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=29.5652173913043, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=34.375, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=30.3418803418803, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=32.7272727272727, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=28.6995515695067, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 23922; Mature: 23922

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLIVEDEPALGETLRAYLAKDGQAVLATSLAQANERVAQISPDVIILDLSMPDGDGLT
CCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
WLAQWRKHLTARVIVLTANDEELTMLKGLRLADDYVVKPVSLRVLKARIAKQLPMTVQQF
HHHHHHHCCEEEEEEEEECCCHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCHHHHHC
GAVSLNLATGQVTKNETAVVLTAAEYRLLAYFFANPNQILARDQLLAALWDTREQFVADN
CCEEEEEEECCEECCCEEEEEEEHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
TLTVTIKRLREKLEDDPAHTTLIRTVRGMGYFIDG
CCEEEHHHHHHHHCCCCHHHHHHHHHHHCCEEECC
>Mature Secondary Structure
MNYLIVEDEPALGETLRAYLAKDGQAVLATSLAQANERVAQISPDVIILDLSMPDGDGLT
CCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
WLAQWRKHLTARVIVLTANDEELTMLKGLRLADDYVVKPVSLRVLKARIAKQLPMTVQQF
HHHHHHHCCEEEEEEEEECCCHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHCCHHHHHC
GAVSLNLATGQVTKNETAVVLTAAEYRLLAYFFANPNQILARDQLLAALWDTREQFVADN
CCEEEEEEECCEECCCEEEEEEEHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
TLTVTIKRLREKLEDDPAHTTLIRTVRGMGYFIDG
CCEEEHHHHHHHHCCCCHHHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]