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The map label for this gene is secA

Identifier: 116494436

GI number: 116494436

Start: 906567

End: 908930

Strand: Direct

Name: secA

Synonym: LSEI_0929

Alternate gene names: 116494436

Gene position: 906567-908930 (Clockwise)

Preceding gene: 116494435

Following gene: 116494437

Centisome position: 31.31

GC content: 46.87

Gene sequence:

>2364_bases
ATGGCCAATATTCTTAGAAAATGGGTCGAAAGCGATAAGCGAGAAATCGCGCGCCTAGGCAAAATTGCTGATAAGGTTCA
GCAATATGAAGATGAGTATGCAGCATTATCTGATGAACAATTAAAAGCAAACACACCAAAATTAAAAGATCGTCTCGCAG
CTGGTGCTACCCTTGATGACATTCTGCCAGAAGCCTTTGCGACTGCGCGGGAAGGTGCCAAGCGTGTTTTAGGTCTATTC
CCGTTCCGAGTCCAAATTATTGGCGGGATTGTGTTGCATGAAGGCAACATTGCGGAGATGAAGACCGGTGAAGGGAAAAC
TTTAACCGCAACCATGCCTGTTTATTTGAACGCACTCACTGGTAAAGGTGTGCATGTTGTCACGGTCAATGAGTACCTGT
CAACCCGTGATGCCACGGAAATGGGCGAGCTATACAACTGGCTTGGCTTGAGCGTAGGGTTAAACCTCAATTCCAAGAAC
AGTGATGAAAAACGAGAAGCTTATAATTGCGACATTACCTATTCCACGAACAGTGAACTCGGGTTTGACTATCTGCGTGA
CAACATGGTTGTTTACAAAGAGCAGATGGTTCAGCGGCCACTGAATTTTGCAATCGTCGATGAAGTTGACTCTATTTTGA
TTGATGAGGCGCGAACCCCATTGATCATTTCTGGCGGCGCAGAAAAAACAACCGGTCTCTACATTCGTGCCGATCGGTTT
GTCAAGACGCTAAAAGCGGAGACCGATTACAAGATCGACTGGCCAACGAAGACAATCTCGTTAACTGAAAGCGGCATCCG
GAAGGCTGAAAAGAATTTCGGACTGGATAATCTGTATGACACCGAAAATACGGCCTTAACGCATCATATTGATCAGGCCT
TGCGGGCTAATTACATCATGCTCAAGGATATCGATTACATGGTTTCCGATGGTGAAGTCCTCATTGTTGATCAGTTTACT
GGCCGAGCAATGGAAGGTCGCCGATATTCTGACGGCTTGCATCAGGCGATTGAAGCCAAAGAAGGCGTCCAAATTCAGGA
CGAAAATAAGACGATGGCTAACATCACTTATCAAAACTTCTTCCGGATGTACACCAAGTTGGCTGGGATGACTGGGACCG
CAAAGACCGAGCAAGAAGAATTCCGAGAAATTTATAACATGGAAGTCATCTCTGTTCCGACCAACAAGCCAGTTATCCGG
GTTGACTCCCCCGACGTGCTGTACCCGACGTTAGATGCTAAGTTCAACGCGGTTGTTGAAGACATCAAAGCGCGTCATGA
AAAAGGCCAGCCGATGCTGATTGGGACGGTTGCGATTGAATCGAGTGAACGGCTTAGTAAGCAACTTGATGAAGCCAAGA
TTCCACATACCGTTTTGAACGCGAAGAATCACTTTAAAGAAGCAGAAATCATTATGAATGCTGGCCAACGCGGCGCTGTG
ACGATTGCGACGAACATGGCTGGGCGTGGTACGGATATCAAACTTGGACCTGGTGTCACCGAACTTGGCGGTTTGGCAGT
TATCGGGACGGAACGCCATGAAAGCCGTCGAATTGATAATCAGTTGCGAGGCCGTTCAGGGCGTCAAGGCGATCCAGGTT
CTACACAGTTTTACCTGAGCCTTGAAGATGATCTGATGAAACGCTTTGGTTCTGATCGAATTAAAGCTATGTTGGATCGC
TTTAAGGTGGCGGATGATGATCAGGTGATTCAAAGTCGGATGATTTCACGGCAGGTGGAGTCAGCCCAGAAACGGGTCGA
AGGGAATAACTACGACACGCGGAAGAATACGCTGCAATATGATGATGTGATGCGTGAACAACGCGAGGTCATTTACAAGC
AGCGGCAGCAAGTCATCAATGAACAGGAAACGTTGAAGCCTGTCTTGATGGCTATGATCAATCGAACAATTACACGGATT
GTTCAGACTCATACCCAAGGAGATCAGAAGGACTGGAATCTTGATGCCTTGTACGCTTGGGTCACTGCCAACATGATTGA
TCCTGAGAAATTCAAACGCAGCCAGTTAGATGGCAAGTCGCAAGACGAGTTGATCGGGTTACTGGCCGAGATGGCGGAAA
CCAACTTCCAGCAAAAGAATAAGCAGCTGGGCGATGACGCGCAGATGCTTGAATTCGAAAAAGTTGTTATTTTGCGCGTG
GTTGATTCTGCTTGGACCGATCATATTGATGCGATGGATCAGTTGCGGCAGTCGATCGGATTGCGCGGTTATGGTCAAAT
GAATCCGCTAGTCGAATATCAAGAAGAAGGCTACCGGATGTTTGAAGAAATGATTGCATCAATTGATGATGATGTGACTC
GGCTGTTCATGAAAGCTGAAATCCGACAAAATATTCGCCGTTAA

Upstream 100 bases:

>100_bases
AGATCTTTGTACTGCTCGGTTTTCAATACCCAATGAAAATGTTAAGATACTATAGATATACTGTCAGTTTAATGAAGTTT
CGACAGAGAGGAATCCATTC

Downstream 100 bases:

>100_bases
TAACGGCTTAGCGCCCCGGCACCGCGGCTAAAGCTTGCGGTACTGGGGTGTTTTGAAGCAGTCGCCGACGCACATAGTCA
TGCTACAATAACGCAACTAT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MANILRKWVESDKREIARLGKIADKVQQYEDEYAALSDEQLKANTPKLKDRLAAGATLDDILPEAFATAREGAKRVLGLF
PFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKN
SDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
VKTLKAETDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIMLKDIDYMVSDGEVLIVDQFT
GRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIR
VDSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIPHTVLNAKNHFKEAEIIMNAGQRGAV
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKRFGSDRIKAMLDR
FKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEQETLKPVLMAMINRTITRI
VQTHTQGDQKDWNLDALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNKQLGDDAQMLEFEKVVILRV
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEIRQNIRR

Sequences:

>Translated_787_residues
MANILRKWVESDKREIARLGKIADKVQQYEDEYAALSDEQLKANTPKLKDRLAAGATLDDILPEAFATAREGAKRVLGLF
PFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKN
SDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
VKTLKAETDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIMLKDIDYMVSDGEVLIVDQFT
GRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIR
VDSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIPHTVLNAKNHFKEAEIIMNAGQRGAV
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKRFGSDRIKAMLDR
FKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEQETLKPVLMAMINRTITRI
VQTHTQGDQKDWNLDALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNKQLGDDAQMLEFEKVVILRV
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEIRQNIRR
>Mature_786_residues
ANILRKWVESDKREIARLGKIADKVQQYEDEYAALSDEQLKANTPKLKDRLAAGATLDDILPEAFATAREGAKRVLGLFP
FRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKNS
DEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRFV
KTLKAETDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIMLKDIDYMVSDGEVLIVDQFTG
RAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIRV
DSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIPHTVLNAKNHFKEAEIIMNAGQRGAVT
IATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKRFGSDRIKAMLDRF
KVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEQETLKPVLMAMINRTITRIV
QTHTQGDQKDWNLDALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNKQLGDDAQMLEFEKVVILRVV
DSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEIRQNIRR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=828, Percent_Identity=46.8599033816425, Blast_Score=717, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_LACC3 (Q03AP4)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806170.1
- ProteinModelPortal:   Q03AP4
- SMR:   Q03AP4
- STRING:   Q03AP4
- GeneID:   4419326
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_0929
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12906
- BioCyc:   LCAS321967:LSEI_0929-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 89369; Mature: 89237

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILRKWVESDKREIARLGKIADKVQQYEDEYAALSDEQLKANTPKLKDRLAAGATLDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHCCCCHHH
ILPEAFATAREGAKRVLGLFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALT
HHHHHHHHHHHHHHHHHHHCHHHHHHHCEEEEECCCCCEEECCCCCEEEEECCEEEEEEC
GKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKNSDEKREAYNCDITYSTNSEL
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCEEEECCCCCC
GFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
CHHHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHH
VKTLKAETDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIM
HHHHHCCCCCEEECCCCEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEE
LKDIDYMVSDGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNF
EECCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEHHHHHHH
FRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVE
HHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEECCCCEEECCCCHHHHHHHH
DIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIPHTVLNAKNHFKEAEIIMNAGQRGAV
HHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCEE
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLS
EEEECCCCCCCCEEECCCCHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEE
LEDDLMKRFGSDRIKAMLDRFKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQY
EHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DDVMREQREVIYKQRQQVINEQETLKPVLMAMINRTITRIVQTHTQGDQKDWNLDALYAW
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEHH
VTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNKQLGDDAQMLEFEKVVILRV
HHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IRQNIRR
HHHHHCC
>Mature Secondary Structure 
ANILRKWVESDKREIARLGKIADKVQQYEDEYAALSDEQLKANTPKLKDRLAAGATLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHCCCCHHH
ILPEAFATAREGAKRVLGLFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALT
HHHHHHHHHHHHHHHHHHHCHHHHHHHCEEEEECCCCCEEECCCCCEEEEECCEEEEEEC
GKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNSKNSDEKREAYNCDITYSTNSEL
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCEEEECCCCCC
GFDYLRDNMVVYKEQMVQRPLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYIRADRF
CHHHHHCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHH
VKTLKAETDYKIDWPTKTISLTESGIRKAEKNFGLDNLYDTENTALTHHIDQALRANYIM
HHHHHCCCCCEEECCCCEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEE
LKDIDYMVSDGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNF
EECCCEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEHHHHHHH
FRMYTKLAGMTGTAKTEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVE
HHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEECCCCEEECCCCHHHHHHHH
DIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIPHTVLNAKNHFKEAEIIMNAGQRGAV
HHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCEE
TIATNMAGRGTDIKLGPGVTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLS
EEEECCCCCCCCEEECCCCHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEE
LEDDLMKRFGSDRIKAMLDRFKVADDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQY
EHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DDVMREQREVIYKQRQQVINEQETLKPVLMAMINRTITRIVQTHTQGDQKDWNLDALYAW
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEHH
VTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNKQLGDDAQMLEFEKVVILRV
HHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IRQNIRR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA