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The map label for this gene is ccpA [H]

Identifier: 116494353

GI number: 116494353

Start: 804301

End: 805302

Strand: Direct

Name: ccpA [H]

Synonym: LSEI_0809

Alternate gene names: 116494353

Gene position: 804301-805302 (Clockwise)

Preceding gene: 116494351

Following gene: 116494355

Centisome position: 27.78

GC content: 46.21

Gene sequence:

>1002_bases
TTGGAAAAGCAAACAATTACAATTTATGATGTCGCACGCGAAGCTAATGTCTCAATGGCGACAGTGTCTCGAGTCGTTAA
TGGTAACCCAAATGTGAAACCAGCTACTCGCAAGAAGGTTTTGGAAGTGATCGAACGGCTTGATTATCGGCCGAATGCAG
TTGCTCGTGGTCTGGCAAGCAAGAAGACGACAACTGTCGGGGTAATTATCCCAGATGTCACGAACATGTTCTTCTCAAGC
TTGGCACGGGGGATTGATGATGTTGCCACGATGTACAAGTACAATATCATCTTGGCGAACTCTGATGAAAACAATCAAAA
AGAAGTCACGGTGTTAAACACATTGTTGGCTAAACAAGTGGATGGTTTGATTTTCATGGGCCATGAATTGACTGACTCAA
TTCGTGCTGAATTCTCACGCAGTAAGACCCCTGTTGTGCTTGCTGGCTCAATCGATCCTGACGAACAGGTTGGCAGTGTC
AACATCGATTACGTGGCTGCTGTCGAAGAAGCCACGCGTCAGTTATTGGAAAGCGGCAACAAGCGGGTTGCTCTGGCGAC
CGGTTCATTGACGCATCCGATCAATGGGCAGTTCCGGCTCAAGGGTTACAAACAGGCTCTGGAAAAGGCCGGTGTTGCTT
ATGACGAAAGCCTGATTTTTGAAAATGAGCCAAGCTACCAAGCTGGTTTAGCCTTGTTTGATAAGTTGCAGAAAGTTGGG
GCAACGGCGGTTATTGCAGGTGATGACGAGTTAGCAGTTGGCCTTTTGGATGGCGCAATTGATAAGGGCGTTAAGGTGCC
GGACGACTTTGAAATTATCACCAGCAATAACACCAAACTGACGGAAATGACTCGACCACAACTTACTTCGATTGATCAGC
CATTGTATGATATTGGTGCGGTTGCTATGCGCTTGCTGACCAAGATGATGAATAAAGAAGAGATCGAGGAAAAGACCGTT
ATGCTTGGCTTCGATATTTTGAAGCGTGGTTCAACGAAATAA

Upstream 100 bases:

>100_bases
AAATTCAGTAAAACGCTTGCATTGCTATTTCTATTCTGTTACTTTGGAATGTAAATAGAACTTCGTGATTTCATCTTTTC
ACGACTAAGGAGAAAATCAA

Downstream 100 bases:

>100_bases
TGCCAGCTTTTGTGAGCTGCTTAGCAGACATGTAAAGTCATTAGGGCAAAGAAAAAGGCTTCCAAGCAAATTACTTGGAG
GCCTTTTTTCTTTGCGTTGA

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVIERLDYRPNAVARGLASKKTTTVGVIIPDVTNMFFSS
LARGIDDVATMYKYNIILANSDENNQKEVTVLNTLLAKQVDGLIFMGHELTDSIRAEFSRSKTPVVLAGSIDPDEQVGSV
NIDYVAAVEEATRQLLESGNKRVALATGSLTHPINGQFRLKGYKQALEKAGVAYDESLIFENEPSYQAGLALFDKLQKVG
ATAVIAGDDELAVGLLDGAIDKGVKVPDDFEIITSNNTKLTEMTRPQLTSIDQPLYDIGAVAMRLLTKMMNKEEIEEKTV
MLGFDILKRGSTK

Sequences:

>Translated_333_residues
MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVIERLDYRPNAVARGLASKKTTTVGVIIPDVTNMFFSS
LARGIDDVATMYKYNIILANSDENNQKEVTVLNTLLAKQVDGLIFMGHELTDSIRAEFSRSKTPVVLAGSIDPDEQVGSV
NIDYVAAVEEATRQLLESGNKRVALATGSLTHPINGQFRLKGYKQALEKAGVAYDESLIFENEPSYQAGLALFDKLQKVG
ATAVIAGDDELAVGLLDGAIDKGVKVPDDFEIITSNNTKLTEMTRPQLTSIDQPLYDIGAVAMRLLTKMMNKEEIEEKTV
MLGFDILKRGSTK
>Mature_333_residues
MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVIERLDYRPNAVARGLASKKTTTVGVIIPDVTNMFFSS
LARGIDDVATMYKYNIILANSDENNQKEVTVLNTLLAKQVDGLIFMGHELTDSIRAEFSRSKTPVVLAGSIDPDEQVGSV
NIDYVAAVEEATRQLLESGNKRVALATGSLTHPINGQFRLKGYKQALEKAGVAYDESLIFENEPSYQAGLALFDKLQKVG
ATAVIAGDDELAVGLLDGAIDKGVKVPDDFEIITSNNTKLTEMTRPQLTSIDQPLYDIGAVAMRLLTKMMNKEEIEEKTV
MLGFDILKRGSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=33.434650455927, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1788474, Length=303, Percent_Identity=33.003300330033, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=29.8780487804878, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789202, Length=328, Percent_Identity=29.8780487804878, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787948, Length=339, Percent_Identity=30.6784660766962, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=28.6195286195286, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=28.7974683544304, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI48994940, Length=335, Percent_Identity=28.0597014925373, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790715, Length=335, Percent_Identity=26.2686567164179, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786540, Length=336, Percent_Identity=25, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787906, Length=261, Percent_Identity=25.6704980842912, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786268, Length=304, Percent_Identity=25.3289473684211, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789456, Length=296, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36403; Mature: 36403

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVIERLDYRPNAVARGLAS
CCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCC
KKTTTVGVIIPDVTNMFFSSLARGIDDVATMYKYNIILANSDENNQKEVTVLNTLLAKQV
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHH
DGLIFMGHELTDSIRAEFSRSKTPVVLAGSIDPDEQVGSVNIDYVAAVEEATRQLLESGN
CCEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
KRVALATGSLTHPINGQFRLKGYKQALEKAGVAYDESLIFENEPSYQAGLALFDKLQKVG
CEEEEEECCCCCCCCCEEEECHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCC
ATAVIAGDDELAVGLLDGAIDKGVKVPDDFEIITSNNTKLTEMTRPQLTSIDQPLYDIGA
CEEEEECCCCEEEEHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCHHHHCCCCHHHHHH
VAMRLLTKMMNKEEIEEKTVMLGFDILKRGSTK
HHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVIERLDYRPNAVARGLAS
CCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCC
KKTTTVGVIIPDVTNMFFSSLARGIDDVATMYKYNIILANSDENNQKEVTVLNTLLAKQV
CCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHH
DGLIFMGHELTDSIRAEFSRSKTPVVLAGSIDPDEQVGSVNIDYVAAVEEATRQLLESGN
CCEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
KRVALATGSLTHPINGQFRLKGYKQALEKAGVAYDESLIFENEPSYQAGLALFDKLQKVG
CEEEEEECCCCCCCCCEEEECHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHCC
ATAVIAGDDELAVGLLDGAIDKGVKVPDDFEIITSNNTKLTEMTRPQLTSIDQPLYDIGA
CEEEEECCCCEEEEHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCHHHHCCCCHHHHHH
VAMRLLTKMMNKEEIEEKTVMLGFDILKRGSTK
HHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]