Click here to switch to the map view.

The map label for this gene is yfnA [H]

Identifier: 116494004

GI number: 116494004

Start: 445799

End: 447154

Strand: Direct

Name: yfnA [H]

Synonym: LSEI_0441

Alternate gene names: 116494004

Gene position: 445799-447154 (Clockwise)

Preceding gene: 116494003

Following gene: 116494006

Centisome position: 15.4

GC content: 50.96

Gene sequence:

>1356_bases
ATGCAAAAACGTAAAAAATTAACCTTACTCGAGGTATTCGGTCTCTCGATAGCCATGGTTGCCCCAACTGGCGCCATGTC
CTTCAACACGGCAAGTGCCGCCGCCAATGCGGGCATCAATATGCCCATTGCTTTCTTGCTTGGTGGGATCGGCGTGTTAT
TCGTCGCGATTTCTTTTGTCGAACTTGGCAAGCGCATTCCCGGTGATGGGTCAGCCTATGCTTATAATGCCAAAGCGCTT
GGCGAAAAGGCGGGCTTCATTTCCGGCTGGCTGCTCGTGTTGACGTACGTGACCTTTGTTCTCAGTTCGGGCGCCATTGT
CGGCAATTTTGCTGACGTGTTTTTAAGTCATTTTGGTATTCATTTACCAGTCAACTTGTACAACATCATTGTGCTGCTGC
TTGGCGGCTGGCTTAGCCATAAAGGCATCGAATTCTCGACAAGGCTAACGCTGGTGCTTGAGCTGTTGGCGGTTTTGGTG
CTGAGTGTCCTGACTGTCGTGATCATTTTCTCAGGTGGTCGCAGCGGCAATTCAGTTCAGCCGTTTATTCCACAACCGCA
TATGGCGACCGGCCTGGGGATGGGCATGGTATTTGCTTTGATGTCTTTTGCCGGCTTTGAAGGCTCGGCGACGATTGCGC
CACGGGCCACCCATCCGCGCAAGGCGATTAGTATTGCTTTGCTGGGTGCCGTTAGCTTTGCAGCAATTTTCTACTTTCTT
GTCAGTTACGCCGAAGTCATCGGTTTTGGTTCCGCCCACATCGGCGATCTTGCGAAAAGTACCGCGCCAATGAACTTTCT
TGCGACCCATTATCTAGGCACGAACGCCGCAATTTTCATGGACTTTGCGGCGATGGTTAGTTATTTTGCCTGCTACTTCG
GTGCGCTCAATGCCGGCGCTTTCATGCTGGAAGCTTTAGGCAAAAGTGGCTATCTGCATCCTTGGCTGGCAGAACTATCA
GGTGACAAGCAGACCCCGACGCACGCGCTGGATGGCATCACTGGCTTAGCGTTAATCGTTTATGCGATTTTTGCAATCGG
CTTAGGTGTGAGCGCGAGCGACATGTACAACTGGTTCGGAACGATTGGCATGCTCGGCTTGCTAACGGTTTACGTGCTGG
TCAACATTGGCGCCATTGTCTACTTCCGCAAAGACAAGGGGCGATCAATGTTTAAACATGTGTTGGCACCAGTCATCGGC
ATTCTCGTGCTCATTTACCCAATTTACACCAGTCTTTGGCCGATTCCGGCATTCCCGATGAACACCTTCCCATACATCGC
GATCATCTGGTTCCTGATCGGTCTATGGGTCGCAACCAAGCGGCGCAATGTTGAAACGAGTTTAGAAGATTTTTAA

Upstream 100 bases:

>100_bases
CACAAGTGCGATGGCCGTTCTTTGGCCATTGTGTTTGTGGTCCTTATGTGGAGGTTTCTGGGCTGGAGAACGCGTTTAAA
GAGGAGTTCCTTCACTAATC

Downstream 100 bases:

>100_bases
AGTTATGACCCAAAAAAGCTCACCATTTTTGATGGTGGGCTTTTTGATTGGACGTAGGTTGCGACTATCGGTCGGTCGCT
ACAACTTGCGAATGTCTAAT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQKRKKLTLLEVFGLSIAMVAPTGAMSFNTASAAANAGINMPIAFLLGGIGVLFVAISFVELGKRIPGDGSAYAYNAKAL
GEKAGFISGWLLVLTYVTFVLSSGAIVGNFADVFLSHFGIHLPVNLYNIIVLLLGGWLSHKGIEFSTRLTLVLELLAVLV
LSVLTVVIIFSGGRSGNSVQPFIPQPHMATGLGMGMVFALMSFAGFEGSATIAPRATHPRKAISIALLGAVSFAAIFYFL
VSYAEVIGFGSAHIGDLAKSTAPMNFLATHYLGTNAAIFMDFAAMVSYFACYFGALNAGAFMLEALGKSGYLHPWLAELS
GDKQTPTHALDGITGLALIVYAIFAIGLGVSASDMYNWFGTIGMLGLLTVYVLVNIGAIVYFRKDKGRSMFKHVLAPVIG
ILVLIYPIYTSLWPIPAFPMNTFPYIAIIWFLIGLWVATKRRNVETSLEDF

Sequences:

>Translated_451_residues
MQKRKKLTLLEVFGLSIAMVAPTGAMSFNTASAAANAGINMPIAFLLGGIGVLFVAISFVELGKRIPGDGSAYAYNAKAL
GEKAGFISGWLLVLTYVTFVLSSGAIVGNFADVFLSHFGIHLPVNLYNIIVLLLGGWLSHKGIEFSTRLTLVLELLAVLV
LSVLTVVIIFSGGRSGNSVQPFIPQPHMATGLGMGMVFALMSFAGFEGSATIAPRATHPRKAISIALLGAVSFAAIFYFL
VSYAEVIGFGSAHIGDLAKSTAPMNFLATHYLGTNAAIFMDFAAMVSYFACYFGALNAGAFMLEALGKSGYLHPWLAELS
GDKQTPTHALDGITGLALIVYAIFAIGLGVSASDMYNWFGTIGMLGLLTVYVLVNIGAIVYFRKDKGRSMFKHVLAPVIG
ILVLIYPIYTSLWPIPAFPMNTFPYIAIIWFLIGLWVATKRRNVETSLEDF
>Mature_451_residues
MQKRKKLTLLEVFGLSIAMVAPTGAMSFNTASAAANAGINMPIAFLLGGIGVLFVAISFVELGKRIPGDGSAYAYNAKAL
GEKAGFISGWLLVLTYVTFVLSSGAIVGNFADVFLSHFGIHLPVNLYNIIVLLLGGWLSHKGIEFSTRLTLVLELLAVLV
LSVLTVVIIFSGGRSGNSVQPFIPQPHMATGLGMGMVFALMSFAGFEGSATIAPRATHPRKAISIALLGAVSFAAIFYFL
VSYAEVIGFGSAHIGDLAKSTAPMNFLATHYLGTNAAIFMDFAAMVSYFACYFGALNAGAFMLEALGKSGYLHPWLAELS
GDKQTPTHALDGITGLALIVYAIFAIGLGVSASDMYNWFGTIGMLGLLTVYVLVNIGAIVYFRKDKGRSMFKHVLAPVIG
ILVLIYPIYTSLWPIPAFPMNTFPYIAIIWFLIGLWVATKRRNVETSLEDF

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=427, Percent_Identity=22.4824355971897, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082023, Length=431, Percent_Identity=23.6658932714617, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666159, Length=316, Percent_Identity=25.9493670886076, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512776, Length=316, Percent_Identity=25.9493670886076, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668806, Length=404, Percent_Identity=23.7623762376238, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356285, Length=404, Percent_Identity=23.7623762376238, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24668802, Length=404, Percent_Identity=23.7623762376238, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48264; Mature: 48264

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRKKLTLLEVFGLSIAMVAPTGAMSFNTASAAANAGINMPIAFLLGGIGVLFVAISFV
CCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ELGKRIPGDGSAYAYNAKALGEKAGFISGWLLVLTYVTFVLSSGAIVGNFADVFLSHFGI
HHHCCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
HLPVNLYNIIVLLLGGWLSHKGIEFSTRLTLVLELLAVLVLSVLTVVIIFSGGRSGNSVQ
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PFIPQPHMATGLGMGMVFALMSFAGFEGSATIAPRATHPRKAISIALLGAVSFAAIFYFL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSYAEVIGFGSAHIGDLAKSTAPMNFLATHYLGTNAAIFMDFAAMVSYFACYFGALNAGA
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FMLEALGKSGYLHPWLAELSGDKQTPTHALDGITGLALIVYAIFAIGLGVSASDMYNWFG
HHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TIGMLGLLTVYVLVNIGAIVYFRKDKGRSMFKHVLAPVIGILVLIYPIYTSLWPIPAFPM
HHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NTFPYIAIIWFLIGLWVATKRRNVETSLEDF
CCCHHHHHHHHHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure
MQKRKKLTLLEVFGLSIAMVAPTGAMSFNTASAAANAGINMPIAFLLGGIGVLFVAISFV
CCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ELGKRIPGDGSAYAYNAKALGEKAGFISGWLLVLTYVTFVLSSGAIVGNFADVFLSHFGI
HHHCCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
HLPVNLYNIIVLLLGGWLSHKGIEFSTRLTLVLELLAVLVLSVLTVVIIFSGGRSGNSVQ
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PFIPQPHMATGLGMGMVFALMSFAGFEGSATIAPRATHPRKAISIALLGAVSFAAIFYFL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
VSYAEVIGFGSAHIGDLAKSTAPMNFLATHYLGTNAAIFMDFAAMVSYFACYFGALNAGA
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FMLEALGKSGYLHPWLAELSGDKQTPTHALDGITGLALIVYAIFAIGLGVSASDMYNWFG
HHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TIGMLGLLTVYVLVNIGAIVYFRKDKGRSMFKHVLAPVIGILVLIYPIYTSLWPIPAFPM
HHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NTFPYIAIIWFLIGLWVATKRRNVETSLEDF
CCCHHHHHHHHHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]